US20100072104A1 - Blister packaging and method for the temporary storage of products - Google Patents

Blister packaging and method for the temporary storage of products Download PDF

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Publication number
US20100072104A1
US20100072104A1 US12/523,985 US52398508A US2010072104A1 US 20100072104 A1 US20100072104 A1 US 20100072104A1 US 52398508 A US52398508 A US 52398508A US 2010072104 A1 US2010072104 A1 US 2010072104A1
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United States
Prior art keywords
film
layer
blister packaging
receiving compartments
perforated sections
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
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US12/523,985
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English (en)
Inventor
Edwin Kohl
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Individual
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Individual
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Publication of US20100072104A1 publication Critical patent/US20100072104A1/en
Abandoned legal-status Critical Current

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Classifications

    • BPERFORMING OPERATIONS; TRANSPORTING
    • B65CONVEYING; PACKING; STORING; HANDLING THIN OR FILAMENTARY MATERIAL
    • B65DCONTAINERS FOR STORAGE OR TRANSPORT OF ARTICLES OR MATERIALS, e.g. BAGS, BARRELS, BOTTLES, BOXES, CANS, CARTONS, CRATES, DRUMS, JARS, TANKS, HOPPERS, FORWARDING CONTAINERS; ACCESSORIES, CLOSURES, OR FITTINGS THEREFOR; PACKAGING ELEMENTS; PACKAGES
    • B65D75/00Packages comprising articles or materials partially or wholly enclosed in strips, sheets, blanks, tubes, or webs of flexible sheet material, e.g. in folded wrappers
    • B65D75/28Articles or materials wholly enclosed in composite wrappers, i.e. wrappers formed by associating or interconnecting two or more sheets or blanks
    • B65D75/30Articles or materials enclosed between two opposed sheets or blanks having their margins united, e.g. by pressure-sensitive adhesive, crimping, heat-sealing, or welding
    • B65D75/32Articles or materials enclosed between two opposed sheets or blanks having their margins united, e.g. by pressure-sensitive adhesive, crimping, heat-sealing, or welding one or both sheets or blanks being recessed to accommodate contents
    • B65D75/36Articles or materials enclosed between two opposed sheets or blanks having their margins united, e.g. by pressure-sensitive adhesive, crimping, heat-sealing, or welding one or both sheets or blanks being recessed to accommodate contents one sheet or blank being recessed and the other formed of relatively stiff flat sheet material, e.g. blister packages, the recess or recesses being preformed
    • B65D75/367Articles or materials enclosed between two opposed sheets or blanks having their margins united, e.g. by pressure-sensitive adhesive, crimping, heat-sealing, or welding one or both sheets or blanks being recessed to accommodate contents one sheet or blank being recessed and the other formed of relatively stiff flat sheet material, e.g. blister packages, the recess or recesses being preformed and forming several compartments
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B65CONVEYING; PACKING; STORING; HANDLING THIN OR FILAMENTARY MATERIAL
    • B65BMACHINES, APPARATUS OR DEVICES FOR, OR METHODS OF, PACKAGING ARTICLES OR MATERIALS; UNPACKING
    • B65B61/00Auxiliary devices, not otherwise provided for, for operating on sheets, blanks, webs, binding material, containers or packages
    • B65B61/02Auxiliary devices, not otherwise provided for, for operating on sheets, blanks, webs, binding material, containers or packages for perforating, scoring, slitting, or applying code or date marks on material prior to packaging
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B65CONVEYING; PACKING; STORING; HANDLING THIN OR FILAMENTARY MATERIAL
    • B65DCONTAINERS FOR STORAGE OR TRANSPORT OF ARTICLES OR MATERIALS, e.g. BAGS, BARRELS, BOTTLES, BOXES, CANS, CARTONS, CRATES, DRUMS, JARS, TANKS, HOPPERS, FORWARDING CONTAINERS; ACCESSORIES, CLOSURES, OR FITTINGS THEREFOR; PACKAGING ELEMENTS; PACKAGES
    • B65D2575/00Packages comprising articles or materials partially or wholly enclosed in strips, sheets, blanks, tubes or webs of flexible sheet material, e.g. in folded wrappers
    • B65D2575/28Articles or materials wholly enclosed in composite wrappers, i.e. wrappers formed by association or interconnecting two or more sheets or blanks
    • B65D2575/30Articles or materials enclosed between two opposed sheets or blanks having their margins united, e.g. by pressure-sensitive adhesive, crimping, heat-sealing, or welding
    • B65D2575/36One sheet or blank being recessed and the other formed or relatively stiff flat sheet material, e.g. blister packages
    • B65D2575/361Details
    • B65D2575/362Details with special means for gaining access to the contents
    • B65D2575/367Details with special means for gaining access to the contents through a preformed opening in the flat sheet, e.g. the opening being defined by weakened lines

Definitions

  • the invention relates to a blister packaging for the temporary storage of products, in particular medicaments, and also to an accompanying method for the temporary storage of such products in a blister packaging.
  • a blister packaging for the weekly medicament requirements of a patient who is supposed to take the medicaments in a sequence organised according to date, day of the week and time of day (morning, midday and evening and/or night) is known from DE 10 2004 034 024 A2.
  • the receiving compartments in the blister packaging for receiving the respective medicaments are arranged in the form of a matrix and have seven “Day” columns with at least three “Time-of-day” compartments in each case, which are occluded, as a whole, by a continuous blister-pack film.
  • Located on the blister packaging is a cover in the form of cardboard, which contains, in a manner specific to the individual patient, the combination in the individual “Time-of-day” compartments and also prescription information relating to the respective medicaments.
  • such packaging units constitute an aid to, on the one hand, not forgetting to take important medicaments and, on the other hand, also reliably keeping track of which medicaments have already been taken, in order to avoid over-medication which may, under certain circumstances, be harmful.
  • An installation for provisioning such packaging units with the desired combination of medicaments is known from DE 10 2004 020 510 A1 and also from WO 2005 102 841 A1.
  • an individually assigned distributing station is provided, which conveys the respective medicaments, by means of plungers which are associated, spatially, with the receiving compartments in the packaging unit, out of a passing packaging in the form of a strip-type blister pack and into the corresponding receiving compartments in the packaging unit. It is thus possible to safely and reliably fill packaging units which are specific to individual patients with a selection from several hundred medicaments in a fully automatic manner.
  • the strip-type blister packs Since the medicaments processed by the packaging installation are prescribed in very different quantities, relatively long “dwell times” in the passing packagings, i.e. the strip-type blister packs, can occur in the case of those medicaments that are rarely prescribed. In order to prevent the medicaments from becoming unusable because of the penetration of moisture or the like, the strip-type blister pack must therefore have satisfactory sealing of the receiving space for the medicament, particularly against water vapour. Sealing of this kind can be achieved, for example, by means of an aluminium film with a minimum thickness of 0.002 mm.
  • the packaging installation is to be capable of processing medicaments of the most diverse sizes and shapes.
  • U.S. Pat. No. 7,093,716 describes a child-proof blister packaging for medicaments which has a number of receiving compartments, each occluded by a film which has three layers.
  • the outermost layer of film is constructed from cardboard material and has tear-open sections which are formed by perforated lines and which are difficult for small children to open.
  • a blister packaging for the temporary storage of products, in particular medicaments which has a number of receiving compartments, which are occluded by a film in each case, for at least one product unit in each case, which film is formed by a first and a second layer of film, wherein perforated sections constructed in the second layer of film, which form a defined tear-open line in the film when a mechanical force is exerted on said film via the product unit, are associated with the receiving compartments in each case.
  • the first layer of film which preferably consists of a material which is impermeable to air and water vapour, such as aluminium or plastic for example, permits secure sealing of the medicaments, even in the case of long dwell times.
  • the second layer of film which preferably consists of a mechanically stiff material, such as paper or cardboard for example, prevents unintended tearing-open of the first layer of film, so that the latter can be of comparatively thin construction.
  • the perforated sections in the second layer of film facilitate the, preferably mechanical, removal of the medicaments from the strip-type blister pack.
  • the first and second layers of film are preferably bonded to one another, so that tearing-off of the aluminium film in the course of the expelling operation, and therefore the possibility of remnants of film falling into the “Week” blister pack, is avoided.
  • the first layer of film which preferably consists of a material which is impermeable to air and water vapour, such as aluminium or plastic for example, occludes the receiving compartments, for example, and the second layer of film is constructed on the first layer of film.
  • the perforation is preferably adapted to the shape and/or size of the product unit which is received in the receiving compartment.
  • the first layer of film may have, for example, a thickness of 0.002 mm to 0.05 mm
  • the second layer of film may have a thickness of 0.05 to 0.5 mm.
  • the depth of the perforation preferably corresponds to the thickness of the second layer of film.
  • the second layer of film may have a machine-readable identifier on its outer side for product identification.
  • the outer side of the second layer of film is preferably provided with a dark surface. This dark surface also facilitates the applying of the perforation in the second layer of film by means of a controlled laser beam which removes said second layer of film (which consists of paper material, for example) by thermal action, while the first layer of film (which consists of aluminium, for example) is not damaged by the laser beam.
  • the blister packaging may preferably be constructed as an endless strip-type blister pack.
  • the invention also proposes a method for the temporary storage of products, in particular medicaments, in a number of receiving compartments in a blister packaging which are occluded by a film in each case, which film is formed by a first and a second layer of film, said method comprising the following steps: the mechanical filling of the receiving compartments with at least one product unit in each case; the occluding of the receiving compartments by means of the film; the providing of the second layer of film with perforated sections in the region of the receiving compartments, which perforated sections form a defined tearing-open line in the film when a mechanical force is exerted upon said film via the product unit; and the mechanical removal of the products from the receiving compartments as a result of the exerting of a mechanical force on the film via the product unit ( 30 ), said film tearing open along the perforated sections.
  • the method step for forming the perforated sections in the second layer of film is preferably performed by means of a laser beam.
  • the method step for mechanically removing the products from the receiving compartments may advantageously be performed by means of cyclically controlled plungers associated with each of said receiving compartments.
  • the method step for forming the perforated sections in the second layer of film may preferably be carried out, for example, prior to the method step for mechanically filling the receiving compartments with the products, in order to permit the most efficient possible course of development of the method.
  • the manufacture of the perforated sections by means of a laser beam can be adjusted to different sizes and shapes of medicament in a flexible manner, so that, with the method according to the invention, a number of different medicaments can be packed away, one after another, in respective endless strip-type blister packs for temporary storage.
  • FIG. 1 shows a diagrammatic side view of a strip-type blister pack.
  • FIG. 2 shows an enlarged diagrammatic side view of one exemplified embodiment of the blister packaging according to the invention.
  • FIG. 3 shows a top view of the film side of a first exemplified embodiment of the blister packaging according to the invention.
  • FIG. 4 shows a top view of the film side of a second exemplified embodiment of the blister packaging according to the invention.
  • FIG. 5 is a flow chart for explaining the method steps in one exemplified embodiment of the method according to the invention.
  • FIG. 1 shows a diagrammatic side view of a strip-type blister pack for the temporary storage of products, in particular medicaments.
  • the product units are individually poured, preferably mechanically, into the blister packaging which is constructed as a strip-type blister pack 20 .
  • One full strip-type blister pack at a time of each sort of medicament is made available to the “Week” blister pack provisioning installation as a product stock. Since the medicaments processed by the provisioning installation are used up in very different quantities, comparatively long storage periods in the strip-type blister packs can occur.
  • an individually assigned distributing station which conveys the respective medicaments out of the endless strip-type blister pack and into the corresponding receiving compartments in the packaging unit, for example by means of plungers which are associated spatially with the receiving compartments in the strip-type blister pack. It is thus possible to safely and reliably fill “Week” blister packs which are specific to individual patients with a selection from several hundred medicaments in a fully automatic manner.
  • the critical working step in this process is the “repackaging” of the product units from the strip-type blister pack into the “Week” blister pack.
  • the blister packaging 20 has an occluding film 25 consisting of a first layer of film 24 and a second layer of film 26 , said second layer of film 26 being provided with perforated sections 28 which facilitate removal of the product units from the strip-type blister pack which serves as the passing packaging, and prevent the tearing-off of the aluminium film in the course of the expelling operation.
  • FIG. 2 A first exemplified embodiment of the blister packaging according to the invention is represented in FIG. 2 .
  • the first layer of film 24 which preferably consists of a material which is impermeable to air and water vapour, such as aluminium or plastic for example, occludes the respective receiving compartments 21 for the product units 30 (represented in broken lines) and permits secure sealing of the medicaments, even in the case of fairly long storage periods.
  • the second layer of film 26 which preferably consists of a mechanically stiff material such as paper or cardboard for example, prevents unintended tearing-open of the first layer of film in the event of mechanical deformations, for instance when the strip-type blister pack is wound onto and off from the appertaining stock roll, so that the first layer of film 24 itself may be of comparatively thin construction, which aids the product removing operation.
  • the perforated section 28 in the second layer of film 26 which section is associated with the respective receiving compartments, facilitates the, preferably mechanical, removal of the medicament units.
  • the second layer of film prevents the flap which is formed from the first layer of film and is thrust open, from being torn off.
  • the first and second layers of film are bonded to one another, so that the aluminium film does not tear off in the course of the expelling operation and no remnants of film fall into the “Week” blister pack.
  • the perforated section 28 is preferably adapted to the shape and/or size of the product unit received in the receiving compartment.
  • Two exemplified embodiments of different shapes for the perforation 28 are represented in FIGS. 3 and 4 .
  • the perforated section 28 may consist of a single continuous U-shaped line, as shown in FIG. 3 , or of two separate, mutually complementary perforated sections, as shown in FIG. 4 .
  • Various arrangements of perforations can be conceived of within the scope of the present invention, depending upon the shape of the medicaments.
  • the first layer of film may have, for example, a thickness of 0.002 mm to 0.05 mm
  • the second layer of film may have a thickness of 0.05 mm to 0.5 mm.
  • the depth of the perforation preferably corresponds to the thickness of the second layer of film, but may also have a lesser depth, so that the second layer of film 26 is not completely severed.
  • the second layer of film 26 may have a machine-readable identifier 32 on its outer side for product identification.
  • the perforation 28 is applied to the outer layer of film 26 , preferably by means of a controlled laser beam which removes said second, outer layer of film 26 (which consists of paper material for example) by thermal action, while the first layer of film 24 (which consists of aluminium for example) is not damaged by the laser beam.
  • this layer preferably has a dark surface.
  • step S 4 of the method the receiving compartments 21 in the strip-type blister pack 20 are filled with the product units 30 in a per se known manner, preferably mechanically.
  • the blister-pack compartments 21 are occluded and thereby sealed in a manner impermeable to air and water vapour, likewise in a per se known manner, by the application, for example the welding-on or sealing-on, of the blister film 25 .
  • the action of a force is finally exerted on the occluding film 25 by the product units 30 themselves by means of the plungers described above, so that said film tears open in a defined manner along the perforated sections 28 in the upper layer of film 26 , and the product units 30 can thus be removed from the receiving compartments 21 reliably and without delay and repackaged into the “Week” blister packs or the like.
  • the forming of the perforated sections by means of a laser beam can be adjusted to different sizes and shapes of medicament in a flexible manner, so that the invention allows the intermediate storage of a number of different medicaments in strip-type blister packs in successive working steps on the same installation.
  • the invention thus permits the secure temporary storage of products, in particular medicaments, even over fairly long periods of time, and also a reliable, preferably mechanical, removal and repackaging of the products in another packaging unit, such as a “Week” blister pack for instance.

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  • Engineering & Computer Science (AREA)
  • Mechanical Engineering (AREA)
  • Chemical & Material Sciences (AREA)
  • Composite Materials (AREA)
  • Packages (AREA)
  • Medical Preparation Storing Or Oral Administration Devices (AREA)
  • Auxiliary Devices For And Details Of Packaging Control (AREA)
US12/523,985 2007-01-22 2008-01-17 Blister packaging and method for the temporary storage of products Abandoned US20100072104A1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP07100898.1 2007-01-22
EP07100898A EP1947027B1 (de) 2007-01-22 2007-01-22 Blisterpackung und Verfahren zur vorübergehenden Lagerung von Produkten
PCT/EP2008/050505 WO2008090079A1 (de) 2007-01-22 2008-01-17 Blisterpackung und verfahren zur vorübergehenden lagerung von produkten

Publications (1)

Publication Number Publication Date
US20100072104A1 true US20100072104A1 (en) 2010-03-25

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US12/523,985 Abandoned US20100072104A1 (en) 2007-01-22 2008-01-17 Blister packaging and method for the temporary storage of products

Country Status (7)

Country Link
US (1) US20100072104A1 (es)
EP (1) EP1947027B1 (es)
JP (1) JP2010516572A (es)
AT (1) ATE461876T1 (es)
DE (1) DE502007003215D1 (es)
ES (1) ES2340958T3 (es)
WO (1) WO2008090079A1 (es)

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US20120048760A1 (en) * 2010-06-30 2012-03-01 Petra Gerda Karey Oral care package
US20120111746A1 (en) * 2009-07-14 2012-05-10 Hitoshi Tanbo Cigarette package
WO2013130605A1 (en) * 2012-02-27 2013-09-06 Frito-Lay North America, Inc. Biodegradable package with sealant layer
US9040120B2 (en) 2011-08-05 2015-05-26 Frito-Lay North America, Inc. Inorganic nanocoating primed organic film
US9090021B2 (en) 2012-08-02 2015-07-28 Frito-Lay North America, Inc. Ultrasonic sealing of packages
US9138378B2 (en) * 2011-07-06 2015-09-22 Sonoco Development, Inc. Blister package and method of forming same
US9149980B2 (en) 2012-08-02 2015-10-06 Frito-Lay North America, Inc. Ultrasonic sealing of packages
US9150119B2 (en) 2013-03-15 2015-10-06 Aesynt Incorporated Apparatuses, systems, and methods for anticipating and delivering medications from a central pharmacy to a patient using a track based transport system
US9162421B2 (en) 2012-04-25 2015-10-20 Frito-Lay North America, Inc. Film with compostable heat seal layer
US9267011B2 (en) 2012-03-20 2016-02-23 Frito-Lay North America, Inc. Composition and method for making a cavitated bio-based film
US9284104B2 (en) 2012-06-23 2016-03-15 Frito-Lay North America, Inc. Deposition of ultra-thin inorganic oxide coatings on packaging
US9511945B2 (en) 2012-10-12 2016-12-06 Aesynt Incorporated Apparatuses, systems, and methods for transporting medications from a central pharmacy to a patient in a healthcare facility
US20170107048A1 (en) * 2015-10-14 2017-04-20 Empire Technology Development Llc Fruit in a bubble wrap mat
US10450126B2 (en) 2011-07-06 2019-10-22 Sonoco Development, Inc. Die-cut patterns for blister package
US20230068772A1 (en) * 2020-01-17 2023-03-02 Sacmi Imola S.C. Method for the production and filling of containers designed to contain food
US20230312208A1 (en) * 2022-03-31 2023-10-05 Huhtamaki Flexible Packaging Germany Gmbh & Co. Kg Push-through cover foil with a plurality of non-intersecting material weakenings and push-through pack with such a cover foil

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JP2011050697A (ja) * 2009-09-04 2011-03-17 Daido Kako Kk 薬剤収納容器
FR2970645B1 (fr) * 2011-01-21 2014-03-28 Ethilog Systeme automatise de dose unitaire pour la delivrance nominative de medicaments
JPWO2014129623A1 (ja) * 2013-02-25 2017-02-02 アステラス製薬株式会社 Ptp包装体及びptp包装体の製造方法

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ES2340958T3 (es) 2010-06-11
EP1947027A1 (de) 2008-07-23
ATE461876T1 (de) 2010-04-15
JP2010516572A (ja) 2010-05-20
DE502007003215D1 (de) 2010-05-06
EP1947027B1 (de) 2010-03-24
WO2008090079A1 (de) 2008-07-31

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