EP1590263B1 - Einstückiger doppelkammerbehälter - Google Patents

Einstückiger doppelkammerbehälter Download PDF

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Publication number
EP1590263B1
EP1590263B1 EP03815692A EP03815692A EP1590263B1 EP 1590263 B1 EP1590263 B1 EP 1590263B1 EP 03815692 A EP03815692 A EP 03815692A EP 03815692 A EP03815692 A EP 03815692A EP 1590263 B1 EP1590263 B1 EP 1590263B1
Authority
EP
European Patent Office
Prior art keywords
container
ampule
auxiliary receptacle
closure
closure device
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
EP03815692A
Other languages
German (de)
English (en)
French (fr)
Other versions
EP1590263A1 (de
Inventor
Bernd Hansen
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Individual
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Publication of EP1590263A1 publication Critical patent/EP1590263A1/de
Application granted granted Critical
Publication of EP1590263B1 publication Critical patent/EP1590263B1/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

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Classifications

    • BPERFORMING OPERATIONS; TRANSPORTING
    • B65CONVEYING; PACKING; STORING; HANDLING THIN OR FILAMENTARY MATERIAL
    • B65DCONTAINERS FOR STORAGE OR TRANSPORT OF ARTICLES OR MATERIALS, e.g. BAGS, BARRELS, BOTTLES, BOXES, CANS, CARTONS, CRATES, DRUMS, JARS, TANKS, HOPPERS, FORWARDING CONTAINERS; ACCESSORIES, CLOSURES, OR FITTINGS THEREFOR; PACKAGING ELEMENTS; PACKAGES
    • B65D25/00Details of other kinds or types of rigid or semi-rigid containers
    • B65D25/02Internal fittings
    • B65D25/04Partitions
    • B65D25/08Partitions with provisions for removing or destroying, e.g. to facilitate mixing of contents
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B65CONVEYING; PACKING; STORING; HANDLING THIN OR FILAMENTARY MATERIAL
    • B65DCONTAINERS FOR STORAGE OR TRANSPORT OF ARTICLES OR MATERIALS, e.g. BAGS, BARRELS, BOTTLES, BOXES, CANS, CARTONS, CRATES, DRUMS, JARS, TANKS, HOPPERS, FORWARDING CONTAINERS; ACCESSORIES, CLOSURES, OR FITTINGS THEREFOR; PACKAGING ELEMENTS; PACKAGES
    • B65D81/00Containers, packaging elements, or packages, for contents presenting particular transport or storage problems, or adapted to be used for non-packaging purposes after removal of contents
    • B65D81/32Containers, packaging elements, or packages, for contents presenting particular transport or storage problems, or adapted to be used for non-packaging purposes after removal of contents for packaging two or more different materials which must be maintained separate prior to use in admixture
    • B65D81/3205Separate rigid or semi-rigid containers joined to each other at their external surfaces
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61JCONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
    • A61J1/00Containers specially adapted for medical or pharmaceutical purposes
    • A61J1/05Containers specially adapted for medical or pharmaceutical purposes for collecting, storing or administering blood, plasma or medical fluids ; Infusion or perfusion containers
    • A61J1/06Ampoules or carpules
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B65CONVEYING; PACKING; STORING; HANDLING THIN OR FILAMENTARY MATERIAL
    • B65DCONTAINERS FOR STORAGE OR TRANSPORT OF ARTICLES OR MATERIALS, e.g. BAGS, BARRELS, BOTTLES, BOXES, CANS, CARTONS, CRATES, DRUMS, JARS, TANKS, HOPPERS, FORWARDING CONTAINERS; ACCESSORIES, CLOSURES, OR FITTINGS THEREFOR; PACKAGING ELEMENTS; PACKAGES
    • B65D1/00Containers having bodies formed in one piece, e.g. by casting metallic material, by moulding plastics, by blowing vitreous material, by throwing ceramic material, by moulding pulped fibrous material, by deep-drawing operations performed on sheet material
    • B65D1/09Ampoules
    • B65D1/095Ampoules made of flexible material
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B65CONVEYING; PACKING; STORING; HANDLING THIN OR FILAMENTARY MATERIAL
    • B65DCONTAINERS FOR STORAGE OR TRANSPORT OF ARTICLES OR MATERIALS, e.g. BAGS, BARRELS, BOTTLES, BOXES, CANS, CARTONS, CRATES, DRUMS, JARS, TANKS, HOPPERS, FORWARDING CONTAINERS; ACCESSORIES, CLOSURES, OR FITTINGS THEREFOR; PACKAGING ELEMENTS; PACKAGES
    • B65D81/00Containers, packaging elements, or packages, for contents presenting particular transport or storage problems, or adapted to be used for non-packaging purposes after removal of contents
    • B65D81/32Containers, packaging elements, or packages, for contents presenting particular transport or storage problems, or adapted to be used for non-packaging purposes after removal of contents for packaging two or more different materials which must be maintained separate prior to use in admixture
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B65CONVEYING; PACKING; STORING; HANDLING THIN OR FILAMENTARY MATERIAL
    • B65DCONTAINERS FOR STORAGE OR TRANSPORT OF ARTICLES OR MATERIALS, e.g. BAGS, BARRELS, BOTTLES, BOXES, CANS, CARTONS, CRATES, DRUMS, JARS, TANKS, HOPPERS, FORWARDING CONTAINERS; ACCESSORIES, CLOSURES, OR FITTINGS THEREFOR; PACKAGING ELEMENTS; PACKAGES
    • B65D81/00Containers, packaging elements, or packages, for contents presenting particular transport or storage problems, or adapted to be used for non-packaging purposes after removal of contents
    • B65D81/32Containers, packaging elements, or packages, for contents presenting particular transport or storage problems, or adapted to be used for non-packaging purposes after removal of contents for packaging two or more different materials which must be maintained separate prior to use in admixture
    • B65D81/3277Ampoules
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61JCONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
    • A61J1/00Containers specially adapted for medical or pharmaceutical purposes
    • A61J1/14Details; Accessories therefor
    • A61J1/20Arrangements for transferring or mixing fluids, e.g. from vial to syringe
    • A61J1/2003Accessories used in combination with means for transfer or mixing of fluids, e.g. for activating fluid flow, separating fluids, filtering fluid or venting
    • A61J1/202Separating means
    • A61J1/2027Separating means having frangible parts
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61JCONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
    • A61J1/00Containers specially adapted for medical or pharmaceutical purposes
    • A61J1/14Details; Accessories therefor
    • A61J1/20Arrangements for transferring or mixing fluids, e.g. from vial to syringe
    • A61J1/2093Containers having several compartments for products to be mixed
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10STECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S206/00Special receptacle or package
    • Y10S206/82Separable, striplike plural articles
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10STECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S215/00Bottles and jars
    • Y10S215/08Mixing

Definitions

  • the invention relates to a container having an opening for dispensing contained in the container flowable or pourable materials and with a closure device closing the opening, which is removable to release the opening according to the feature configuration of claim 1.
  • Containers of this type which are filled with ingredients to be dispensed, are known in various forms and for different uses of the dispensed ingredients. For example, they may be ampule-type containers containing pharmaceuticals to be dispensed from the container for injection, infusion, or the like.
  • the respective removal opening is for both the ampoule and for the auxiliary container in a neck part, which is not part of the extension, and the neck parts are inclined towards each other with a predetermined removal angle, so that at a fluid removal from the container product, the fluid delivery outside of the same common place.
  • a mixture of the container contents outside of the container can be carried out with essentially only one actuating step.
  • the mixing of the fluid contents outside of the container product leads to an impairment of the sterility of the respective fluid, which was still guaranteed before delivery within the container.
  • simultaneous manual operation of the ampule and the auxiliary container it is difficult to provide uniform fluid or media delivery, thus compromising the result of mixing outside of the container product.
  • the two chambers of a dual-chamber container in particular a dual-chamber ampoule, by two juxtaposed and releasably interconnected ampoules with substantially the same Structure and formed with a jointly removable closure as a closure device for both ampoules.
  • the one ampoule has a neck forming the filling and / or removal opening with a conical outer lateral surface tapering towards the free end of the neck, and the other ampoule has a neck forming the filling and / or removal opening with an inner cone corresponding to the one Outer cone of the other ampoule is formed and tapers towards the interior of the ampoule.
  • a type of coupling sleeve is obtained for the formation of a sealed passage between the two ampoules. Furthermore, in turn, on the side facing away from the common closure device to the two ampoules joins a common extension with corresponding predetermined breaking points for the separation of the two ampoules from each other, wherein the extension serves as a grip surface and offers an opportunity for labeling the container product corresponding identification, for example, in the form of a label to install.
  • This known, closest solution thus has a common closure device for both ampoules and said common extension in the form of the handle surface ends in the region of the neck portion of each ampoule, so that the closure device is not part of this extension.
  • the invention has the object to provide a container which is improved over the known solutions and in particular allows a simplified storage and handling.
  • the proposed releasable connection between the container and the auxiliary container containing the additive simplifies the storage, because both means, although they are separated from each other, form a storage unit.
  • the handling required for the delivery of the substance is particularly simplified because the addition of the additive to the container contents is particularly simple and convenient in the way that the auxiliary container with its outlet device with the opening of the container can be coupled.
  • the unit of container and auxiliary receptacle attached to its opening may be shaken to effect, for example, a required mixing of the two agents or, if the additive is a pourable agent of particular particle size, for example in the form of a single large particle, such as a tablet to effect passage through the passageway between the auxiliary container and the container.
  • the container is advantageously after in the art as bottelpack ® - System produced by known methods. This method enables automated molding (blowing or vacuum forming), filling and sealing of containers in an economical manner.
  • the container with its closure device and the auxiliary container with its closure made of plastic as a one-piece body are formed on the weak points that form predetermined breaking points at which the closure device of the container and the Auxiliary container for removal from the container can be separated. In the simplest way can thereby both open the container and remove the auxiliary container to handle this separately.
  • a weak point is also formed on the outlet of the auxiliary container, which forms a predetermined breaking point for the separation of the closure of the auxiliary container for the release of the outlet device.
  • the container is a type of ampoule, the opening of which is provided on a neck portion projecting coaxially with the ampoule main axis
  • the body forming the unit of container and auxiliary container may be formed so as to extend in the direction of the neck area of the ampoule the ampoule main axis extending extension is extended, at which the closure device of the container, the auxiliary container and the weak points forming the predetermined breaking points are formed.
  • This extension of the body may be formed in adjacent to the closure device of the container and to the closure of the auxiliary container portions in the form of flat plates, so that grip surfaces are formed by means of which the closure device and the auxiliary container can be easily separated by means of the predetermined breaking points of the container.
  • the invention is illustrated by the example of an ampoule-like container, which is made in one piece according to the known in the art bottelpack ® system made of thermoplastic polymeric material.
  • this method of manufacturing and filling containers at least one tube of plasticized plastic material is extruded into an open mold.
  • the course of closing lower Moldings are performed on the hose welding operations to form the container bottom.
  • the hose, or in the formation of a plurality of containers, the hoses, is or are cut above the mold to form a respective filling opening by means of a separating element.
  • the mold is then moved with the unit having the open fill opening or open fill openings to a fill position in which the container (s), after being inflated by blown air or vacuum forming the container mold, is provided with the contents. Then, a head welding operation is performed on the top of the container or containers, thereby making the closure of the filled unit.
  • Fig. 1 shows a unit manufactured according to the bottelpack ® system with a one-piece body designated as a whole by 1, at which the filled, ampoule-like container 3 forms the lower body end portion.
  • the container 3 has a to the ampoule main axis 5 coaxially upwardly projecting neck portion 7 with the container opening 8.
  • neck portion 7 he stretches in the direction of the main vial axis 5, a body extension 9 upwards, on which, as in Fig. 1 is shown, a closure of the opening 8 of the container forming closure device 11 and an auxiliary container 13 are formed as integral parts of the body extension 9.
  • weak points 21 are formed, which form predetermined breaking points for the separation of the components and the case taking place taking off the closure device 11 of the container opening 8.
  • FIGS. 2 and 3 show the body extension 9 subregions in the form of flat plates 15, 17 and 19. These form gripping surfaces, with the aid of which the components forming the body extension 9 can be removed from the break-off points of the ampule-type container 3 are.
  • Fig. 2 shows the operating state in which the auxiliary container 13 is removed from the rest of the unit.
  • Fig. 3 shows a next operating state in use, in which by means of the gripping surfaces 17 and 19 of the closure 23 of the auxiliary container 13 is removed by disconnecting at a respective predetermined breaking point to expose the outlet means 25 of the auxiliary container 13.
  • Fig. 3 in that, with the aid of the gripping surface 15, the closure device 11 is separated from the neck region 7 of the container 3, in order to release its opening 8.
  • Fig. 4 shows the following in use stage, in which the auxiliary container 13 is brought with the additive contained therein in the form of a tablet 27 to the opening 8 of the container 3 to pour the tablet 27 via the outlet means 25 and the opening 8 in the container 3 ,
  • the outlet means 25 forms on the auxiliary container 13 to the neck portion 7 of the container 3 suitable, attachable to the neck portion 7 coupling sleeve 29, by means of which a sealed-to-outside passage between the auxiliary container 13 and the interior of the container 3 can be formed.
  • the thus formed, reclosed unit can now be shaken to dissolve the input into the container 3 tablet 27 in the desired manner and to mix the so introduced into the container 3 additive with the rest of the container contents.
  • Fig. 6 shows that after removing the auxiliary container 13 provided with the additive content of the container 3 can be output via the now exposed opening 8.
  • auxiliary container 13 which is to be added to the contents of the container 3. It can also be seen that for the container 3 and the auxiliary container 13 other container shapes As shown in the drawing, can be provided and that instead of the aforementioned bottelpack ® system other manufacturing methods for forming the container and auxiliary container unit can be applied.

Landscapes

  • Engineering & Computer Science (AREA)
  • Mechanical Engineering (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Hematology (AREA)
  • Ceramic Engineering (AREA)
  • Medical Preparation Storing Or Oral Administration Devices (AREA)
  • Package Specialized In Special Use (AREA)
  • Closures For Containers (AREA)
  • Packages (AREA)
EP03815692A 2003-02-05 2003-11-13 Einstückiger doppelkammerbehälter Expired - Lifetime EP1590263B1 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
DE10304500 2003-02-05
DE2003104500 DE10304500A1 (de) 2003-02-05 2003-02-05 Behälter
PCT/EP2003/012677 WO2004069686A1 (de) 2003-02-05 2003-11-13 Einstrückiger doppelkammerbehälter

Publications (2)

Publication Number Publication Date
EP1590263A1 EP1590263A1 (de) 2005-11-02
EP1590263B1 true EP1590263B1 (de) 2013-02-20

Family

ID=32747552

Family Applications (1)

Application Number Title Priority Date Filing Date
EP03815692A Expired - Lifetime EP1590263B1 (de) 2003-02-05 2003-11-13 Einstückiger doppelkammerbehälter

Country Status (15)

Country Link
US (1) US7537131B2 (ja)
EP (1) EP1590263B1 (ja)
JP (1) JP4343849B2 (ja)
KR (1) KR20050099988A (ja)
CN (1) CN100423998C (ja)
AU (1) AU2003303858B2 (ja)
BR (1) BR0318089B1 (ja)
CA (1) CA2513800C (ja)
DE (1) DE10304500A1 (ja)
ES (1) ES2400463T3 (ja)
HK (1) HK1087676A1 (ja)
MX (1) MXPA05008376A (ja)
PL (1) PL202756B1 (ja)
PT (1) PT1590263E (ja)
WO (1) WO2004069686A1 (ja)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NZ577236A (en) * 2006-12-15 2012-01-12 Romuald Yip Watering can to receive two liquids in separate chambers, each with an aperture and volume graduations, the smaller volume mixes into the larger volume, the mixture pours out of a spout
CN101663206B (zh) * 2007-04-27 2011-05-11 大和制罐株式会社 聚酯树脂制带有待破裂部的容器及其制造方法
US8464918B1 (en) * 2010-01-29 2013-06-18 Unicep Packaging, Inc. Child resistant closure for unit-dose packaging
JP5916067B2 (ja) * 2011-10-28 2016-05-11 株式会社大塚製薬工場 プラスチックアンプル
DE102012007165B4 (de) 2012-04-07 2017-06-14 Manfred Völker Saures Dialysekonzentrat
IT202100004871A1 (it) * 2021-03-02 2022-09-02 Brev Angela Srl Contenitore realizzato tramite un sistema per la formatura e relativo metodo di produzione

Family Cites Families (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3809289A (en) * 1971-12-20 1974-05-07 Automatic Liquid Packaging Mixing containers
DE2638561A1 (de) * 1976-08-26 1978-03-02 Hago Chemie Gmbh & Co Vorrichtung zur getrennten aufbewahrung und anschliessenden vermischung fliessfaehiger und/oder loeslicher stoffe
US4266681A (en) * 1977-02-28 1981-05-12 Oceanography International Corporation Multiple breakpoint resealable ampoule
DE3833036C2 (de) * 1988-09-29 1998-03-19 Bernd Hansen Doppelkammerbehälter
US4964539A (en) 1989-04-06 1990-10-23 Seaquist Closures Multiple chamber dispensing container and closure system
DE4011671C2 (de) * 1990-04-11 1994-04-28 Glyco Metall Werke Regelbare Flügelzellenpumpe
US5114011A (en) * 1990-08-31 1992-05-19 Robbins Edward S Iii Container assemblies with additive cups
DE4405965C2 (de) * 1994-02-24 1997-08-07 Bernd Hansen Infusionsbehälter mit zwei Anschlüssen
US5965164A (en) * 1994-10-28 1999-10-12 Fuisz Technologies Ltd. Recipient-dosage delivery system
US5826737A (en) * 1996-02-20 1998-10-27 Colgate-Palmolive Company Thermoformed reclosable container
US5897009A (en) * 1996-10-18 1999-04-27 Wheaton Usa, Inc. One-piece container closure assemblies
US6022134A (en) * 1996-10-25 2000-02-08 Rxi Plastics, Inc. Mixing and dispensing container
DE19706932A1 (de) * 1997-02-20 1998-08-27 Dentaco Gmbh Mehrkammer-Ampulle für portionierte Flüssigkeiten
US6263923B1 (en) * 1999-05-28 2001-07-24 James A. Castillo Device for maintaining separate ingredients in liquid food products
DE19958920C2 (de) * 1999-12-07 2003-03-20 Automation Industrielle Sa Zweikammerbehälter
US6247617B1 (en) * 1999-12-13 2001-06-19 Richard Allen Clyde Single use container for dispensing separately housed sterile compositions

Also Published As

Publication number Publication date
HK1087676A1 (en) 2006-10-20
PL202756B1 (pl) 2009-07-31
CA2513800C (en) 2010-04-20
PT1590263E (pt) 2013-04-02
MXPA05008376A (es) 2005-11-04
JP4343849B2 (ja) 2009-10-14
ES2400463T3 (es) 2013-04-10
BR0318089A (pt) 2005-12-20
JP2006513933A (ja) 2006-04-27
PL376643A1 (pl) 2006-01-09
AU2003303858A1 (en) 2004-08-30
WO2004069686A1 (de) 2004-08-19
KR20050099988A (ko) 2005-10-17
CN100423998C (zh) 2008-10-08
DE10304500A1 (de) 2004-08-26
US7537131B2 (en) 2009-05-26
BR0318089B1 (pt) 2014-12-30
AU2003303858B2 (en) 2009-12-10
CA2513800A1 (en) 2004-08-19
CN1745023A (zh) 2006-03-08
US20060144853A1 (en) 2006-07-06
EP1590263A1 (de) 2005-11-02

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