EP1572270A1 - Dispositif d'injection pourvu d'une protection d'aiguille - Google Patents

Dispositif d'injection pourvu d'une protection d'aiguille

Info

Publication number
EP1572270A1
EP1572270A1 EP03770836A EP03770836A EP1572270A1 EP 1572270 A1 EP1572270 A1 EP 1572270A1 EP 03770836 A EP03770836 A EP 03770836A EP 03770836 A EP03770836 A EP 03770836A EP 1572270 A1 EP1572270 A1 EP 1572270A1
Authority
EP
European Patent Office
Prior art keywords
sliding sleeve
needle
needle guard
housing
sleeve
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
EP03770836A
Other languages
German (de)
English (en)
Inventor
Edgar Hommann
Benjamin Scherer
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Tecpharma Licensing AG
Original Assignee
Tecpharma Licensing AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Tecpharma Licensing AG filed Critical Tecpharma Licensing AG
Publication of EP1572270A1 publication Critical patent/EP1572270A1/fr
Withdrawn legal-status Critical Current

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178Syringes
    • A61M5/31Details
    • A61M5/32Needles; Details of needles pertaining to their connection with syringe or hub; Accessories for bringing the needle into, or holding the needle on, the body; Devices for protection of needles
    • A61M5/3205Apparatus for removing or disposing of used needles or syringes, e.g. containers; Means for protection against accidental injuries from used needles
    • A61M5/321Means for protection against accidental injuries by used needles
    • A61M5/3243Means for protection against accidental injuries by used needles being axially-extensible, e.g. protective sleeves coaxially slidable on the syringe barrel
    • A61M5/326Fully automatic sleeve extension, i.e. in which triggering of the sleeve does not require a deliberate action by the user
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178Syringes
    • A61M5/20Automatic syringes, e.g. with automatically actuated piston rod, with automatic needle injection, filling automatically
    • A61M5/2033Spring-loaded one-shot injectors with or without automatic needle insertion
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178Syringes
    • A61M5/20Automatic syringes, e.g. with automatically actuated piston rod, with automatic needle injection, filling automatically
    • A61M2005/206With automatic needle insertion
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178Syringes
    • A61M5/20Automatic syringes, e.g. with automatically actuated piston rod, with automatic needle injection, filling automatically
    • A61M2005/2073Automatic syringes, e.g. with automatically actuated piston rod, with automatic needle injection, filling automatically preventing premature release, e.g. by making use of a safety lock
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178Syringes
    • A61M5/31Details
    • A61M5/32Needles; Details of needles pertaining to their connection with syringe or hub; Accessories for bringing the needle into, or holding the needle on, the body; Devices for protection of needles
    • A61M5/3205Apparatus for removing or disposing of used needles or syringes, e.g. containers; Means for protection against accidental injuries from used needles
    • A61M5/321Means for protection against accidental injuries by used needles
    • A61M5/3243Means for protection against accidental injuries by used needles being axially-extensible, e.g. protective sleeves coaxially slidable on the syringe barrel
    • A61M5/3245Constructional features thereof, e.g. to improve manipulation or functioning
    • A61M2005/3247Means to impede repositioning of protection sleeve from needle covering to needle uncovering position
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178Syringes
    • A61M5/31Details
    • A61M5/32Needles; Details of needles pertaining to their connection with syringe or hub; Accessories for bringing the needle into, or holding the needle on, the body; Devices for protection of needles
    • A61M5/3202Devices for protection of the needle before use, e.g. caps

Definitions

  • the application relates to a device for injecting an active substance, with an injection needle, a housing, a container for the active substance and a syringe plunger which is displaceable in the container for the purpose of dispensing the active substance and with a needle guard which can be displaced relative to the housing.
  • a needle guard of the type mentioned is known in many designs, both in connection with manually operated syringes and in so-called auto-injectors.
  • Document W09714455 describes an auto-injector with a needle-protecting sleeve which can be moved in a housing and which rests on the patient's skin during the injection and is biased by a spring such that the needle-protecting sleeve pushes forward relative to the auto-injector when it is pulled back and covers the injection needle , Effective locking means between the needle protection and the housing ensure that the needle protection sleeve cannot be pushed back again and thus there can be no unwanted injury from the injection needle. Means to release the lock are not disclosed in this document.
  • the needle guard remains in a position which is essentially constant relative to the housing, and in the process a spring element is tensioned, which pushes the needle guard into a position surrounding the needle after removal of the injection needle from the skin.
  • a special embodiment of the invention is characterized in that the container is accommodated in a sliding sleeve which is displaced in the housing from a retracted position into an advanced position during skin penetration, that the needle guard is automatically locked in its advanced position by locking means, which locking means are arranged and designed such that they act between the needle guard and the sliding sleeve when the needle guard and the sliding sleeve are in their advanced position and that there are means for releasing the locking means which take effect when the sliding sleeve is at least approximately in their retracted position.
  • the needle guard is therefore not locked against the housing as in many known devices of this type, but the sliding sleeve and the means for releasing the locking only become effective when the sliding sleeve is at least approximately in its retracted position. This has the considerable advantage that the injection needle is already back in the housing when the lock is released. This ensures that the injection needle cannot be touched unintentionally in any operating state of the auto-injector.
  • the locking means have at least one essentially axially aligned spring tongue which is arranged on the sliding sleeve and which in its relaxed state forms an axial stop with a region of the needle guard and the means for releasing the locking have one in the housing arranged, inwardly projecting projection, which presses the spring tongue radially inward in the retracted position of the sliding sleeve, such that the part of the sliding sleeve containing the spring tongue can move into the area of the needle guard.
  • a spring element which urges the needle guard into its advanced position and which is tensioned by the sliding sleeve when it moves into its advanced position.
  • Another embodiment of the invention provides that there are entraining means which cause the needle guard to be taken along by the sliding sleeve when it is moved from its advanced position into the retracted position. This eliminates the need to manually push the needle guard back into the housing after unlocking. If, in addition, a return spring element is provided, which applies a restoring force to the sliding sleeve in the direction of its retracted position, both the sliding sleeve and the needle guard automatically assume the retracted starting position when the driving force ceases.
  • FIG. 1 shows a longitudinal section through an exemplary embodiment of an auto-injector according to the invention in the charged state
  • FIG. 2 shows a longitudinal section through the same auto-injector after inserting the injection needle and pouring out the medicament, the cutting plane being offset by 90 ° with respect to that of FIG. 1,
  • FIG. 3 shows a longitudinal section through the same auto-injector after pulling out the injection needle, cut in the same plane as the illustration according to FIG. 1, and
  • the auto-injector consists of two main components, namely the reservoir part, shown on the left in the figures, which holds a filled syringe 50 and the power pack, shown on the right in the figures, in which the parts which are used for automatically inserting and dispensing the syringe are accommodated are.
  • the two main components are detachably connected to one another by a bayonet-like connection between a housing 16 and a power sleeve 1.
  • the side of the auto-injector on which the injection needle 37 is located is referred to as the front.
  • FIG. 1 shows the ready-to-use auto injector.
  • the parts for driving the auto injector are accommodated in the grip sleeve 14, at the rear end of which a display window 51 connects.
  • the display window 51 is, for example, made of transparent or translucent material, so that the display 12 slidably received in the display window 51 can be observed from the outside.
  • the display 12 allows the user to visually track the process of dispensing the medication.
  • the actuating head 13 is arranged, which is provided on its rear face with a cover plate 15.
  • the power sleeve 1 is received within the grip sleeve 14.
  • the power sleeve 1 is connected to a grid sleeve 8 by means of a snap connection.
  • the grid sleeve 8 receives a spring sleeve 10 slidably on the inside.
  • the spring sleeve 10 is coupled to the display 12 at the rear by a snap connection.
  • the transmission part 5 is slidably mounted in the power sleeve 1.
  • the transfer part 5 has the task of actuating the piston rod 52 of the syringe 50 in order to pour out the contents of the syringe, as will be described in more detail later.
  • a spring 9 is accommodated in the tensioned state within the spring sleeve 10, which is supported on the spring sleeve 10 at the front and presses against the grid sleeve 8 at the rear.
  • a second spring 11 is also located in the tensioned state on the outside of the spring sleeve 10 and is supported at the front on the transmission part 5 and presses against the spring sleeve 10 at the rear.
  • a part referred to as the piston guide 4 rests with its front, sleeve-shaped, slotted end 4 ′ on the collar of the syringe 50 and extends through the transmission part 5, the spring sleeve 10 and the grid sleeve 8 into the area of the actuating head 13.
  • the piston guide 4 is biased forward by a spring 7 which is supported on the grid sleeve 8 at the rear. At its rear end, the piston guide 4 is held in the position shown in FIG. 1 by two locking cams 31 formed on the grid sleeve 8 and engaging in a groove 32 formed on the rear end of the piston guide 4.
  • Locking elements for example balls 6 (only visible in FIG. 2), which are received in radial openings 33 of the piston guide 4 and engage in recesses 34 in the transmission part 5, ensure in this operating position that the transmission part 5 and the piston guide 4 only move together can.
  • balls 6 instead of balls 6, other bodies can also be used as locking elements, for example bolts.
  • the syringe 50 is accommodated in the housing 16, which can be connected to the power sleeve 1 as described.
  • a sliding sleeve 21 accommodates the syringe 50 with the interposition of a needle holder 22 (FIG. 2).
  • the needle holder 22 prevents the injection needle 37 from being pulled off the syringe as long as the latter is in the auto-injector.
  • the needle holder 22 lies against a support ring 24 connected to the sliding sleeve 21 at the front.
  • the sliding sleeve 21 is displaceable within the housing 16 and is forced into the operating position shown in FIG. 1 by a spring 20.
  • the spring 20 which is in its only slightly pretensioned state in the operating position according to FIG. 1, is supported at the front on a circumferential, inner shoulder 39 of the housing 16 and at the rear on an outwardly projecting rim of the sliding sleeve 21.
  • a sleeve-shaped needle guard 17 is slidable within the housing 16.
  • the needle guard 17 is closed at the front by a snap cover 23, which leaves a passage for the injection needle 37 and has an inwardly facing flange 35 at its rear end.
  • a spring 18 is supported at the front on the snap cover 23 and at the back on a driving ring 19, which in turn is supported on the flange 35 in the operating position according to FIG. 1. Consequently, the spring 18 has no effect in the operating position according to FIG. 1, in which it is only slightly pretensioned, because its remaining pretensioning force is absorbed by the needle guard 17.
  • the auto-injector must be unlocked before the injection can be triggered.
  • the actuating head 13 is moved backwards. At the front edge of the actuating head 13, an area of the display window 51 is cleared, on the inside of which a conspicuously colored warning sleeve 53 is visible, which clearly indicates that the auto-injector is now unlocked and ready for injection.
  • tongues 36 which are integrally formed on the cover plate 15 of the actuating head 13, move over the latching cams 31 formed on the grid sleeve.
  • the tongues 36 and the latching cams 31 are shaped in such a way that the tongues 36 yield radially resiliently while sliding over the ends of the locking cams 31, which hold the piston guide 4 by engaging in the grooves 32 mentioned.
  • the tongues 36 formed on the actuating head 13 stand like wedges between the locking cams 31.
  • the auto-injector is now ready for injection and is placed on the patient's skin at the desired location with the snap cover 23. Since the needle guard 17 has an axial play in the housing 16, it pushes backwards when it is placed on the skin until the flange 35 abuts the shoulder 39. The patient holds the auto-injector firmly on the grip sleeve 14 and moves the actuating head 13 forward, that is, in the direction towards his body. During this release movement, the tongues 36 penetrate between the locking cams 31 and spread them apart radially, as a result of which the piston guide 4 is released and pushed forward by the force of the spring 7. The piercing movement is also supported by the force of the springs 9 and 11, which act on the transmission part 5.
  • a spring system is formed, consisting of the springs 7, 9 and 11 with a relatively high initial force, which contributes to the injection needle being reliably advanced to the full penetration depth .
  • the force of the springs is transmitted via the sleeve-shaped front end 4 'of the piston guide 4 to the collar of the syringe 50 and pushes it together with the sliding sleeve 21 in which it is received in front, so that the injection needle 37 is advanced and penetrates the patient's skin.
  • the front end of the sliding sleeve 21 moves into the needle guard 17, the spring tongues 38 provided on it driving the driving ring 19 and thus tensioning the spring 18.
  • the sliding sleeve 21 also compresses the spring 20.
  • the penetration stroke is limited by the shoulder 40 of the piston guide 4 resting on an inner shoulder 41 of the power sleeve 1.
  • the openings 33 in the piston guide 4, which receive the balls 6, are aligned with recesses 42, which are provided in the power sleeve 1, the balls 6 can deflect outwards and the coupling between the piston guide 4 and the transmission part 5 is canceled.
  • the piston guide 4 is now locked against the power sleeve 1, so that the force of the spring 20 is absorbed by the power sleeve and does not counteract the force of the spring 7.
  • FIG. 2 shows the operating position of the auto-injector just described, in which the medicament has been completely poured out, as can be seen in the figure on the basis of the position of the piston rod of the syringe 50.
  • the user can clearly recognize this operating position on the basis of the position of the display 12 in the display window 51.
  • the reference number 57 denotes the body tissue of the patient in which the injection needle 37 is still inserted.
  • the user can now withdraw the auto-injector, which changes into the operating position shown in FIG. 3.
  • the spring 18, which was pretensioned during the puncturing process as described, ensures that the needle guard 17 remains in contact with the patient's skin during the retraction of the auto-injector.
  • the needle guard 17 moves forward relative to the housing 16 and the sliding sleeve 21 until it completely covers the injection needle 37.
  • the spring tongues 38 snap behind the flange 35 of the needle guard 17 and prevent it from being pushed back into the housing 16, as can be clearly seen in FIG. 3. This means that every further wanted injury from the hypodermic needle to be eliminated.
  • Small hooks 58 (FIG.
  • FIG. 4 shows the reservoir part in this operating position, in which the used syringe 50 can now be removed and replaced by a new one.

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Hematology (AREA)
  • Anesthesiology (AREA)
  • Biomedical Technology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Vascular Medicine (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Environmental & Geological Engineering (AREA)
  • Infusion, Injection, And Reservoir Apparatuses (AREA)

Abstract

Selon l'invention, un contenant (50) à principe actif est relié à une aiguille d'injection (37) et logé dans une douille coulissante (21) qui peut être déplacée par une force d'entraînement dans un corps (16). Une protection d'aiguille (17) en forme de manchon peut être déplacée dans ledit corps (16) par la force d'un ressort (18) de telle sorte que, lors du retrait de l'aiguille d'injection (37) d'un tissu corporel, cette protection est déplacée vers l'avant et recouvre axialement l'aiguille d'injection (37). Des moyens de verrouillage (35, 38) empêchent que la protection d'aiguille (17) soit ramenée en arrière manuellement. Ces moyens de verrouillage (35, 38) agissent entre la protection d'aiguille (17) et la douille coulissante (21), le verrouillage étant automatiquement supprimé lorsque la douille coulissante (21) se trouve de nouveau au moins dans une position proche de sa position rétractée.
EP03770836A 2002-11-25 2003-11-17 Dispositif d'injection pourvu d'une protection d'aiguille Withdrawn EP1572270A1 (fr)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
CH19862002 2002-11-25
CH198602 2002-11-25
PCT/CH2003/000757 WO2004047892A1 (fr) 2002-11-25 2003-11-17 Dispositif d'injection pourvu d'une protection d'aiguille

Publications (1)

Publication Number Publication Date
EP1572270A1 true EP1572270A1 (fr) 2005-09-14

Family

ID=32331828

Family Applications (1)

Application Number Title Priority Date Filing Date
EP03770836A Withdrawn EP1572270A1 (fr) 2002-11-25 2003-11-17 Dispositif d'injection pourvu d'une protection d'aiguille

Country Status (6)

Country Link
US (2) US7361160B2 (fr)
EP (1) EP1572270A1 (fr)
JP (1) JP4339260B2 (fr)
CN (1) CN100506305C (fr)
AU (1) AU2003280270B2 (fr)
WO (1) WO2004047892A1 (fr)

Families Citing this family (133)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP3993169B2 (ja) 2002-02-11 2007-10-17 アンタレス・ファーマ・インコーポレーテッド 皮内注射器
EP1572270A1 (fr) * 2002-11-25 2005-09-14 Tecpharma Licensing AG Dispositif d'injection pourvu d'une protection d'aiguille
US20090204076A1 (en) * 2003-02-03 2009-08-13 Barry Peter Liversidge Medical Injector
GB0315600D0 (en) * 2003-07-04 2003-08-13 Owen Mumford Ltd Improvements relating to automatic injection devices
DE10342059B4 (de) * 2003-09-11 2007-03-01 Tecpharma Licensing Ag Verabreichungsvorrichtung mit Einstech- und Ausschütteinrichtung
CH696421A5 (de) 2003-12-18 2007-06-15 Tecpharma Licensing Ag Autoinjektor mit Arretierung des Wirkstoffbehälters.
GB2414775B (en) 2004-05-28 2008-05-21 Cilag Ag Int Releasable coupling and injection device
GB2414402B (en) 2004-05-28 2009-04-22 Cilag Ag Int Injection device
GB2414400B (en) 2004-05-28 2009-01-14 Cilag Ag Int Injection device
GB2414398B (en) * 2004-05-28 2009-04-22 Cilag Ag Int Injection device
GB2414401B (en) * 2004-05-28 2009-06-17 Cilag Ag Int Injection device
GB0414054D0 (en) 2004-06-23 2004-07-28 Owen Mumford Ltd Improvements relating to automatic injection devices
US11590286B2 (en) 2004-11-22 2023-02-28 Kaleo, Inc. Devices, systems and methods for medicament delivery
US7648483B2 (en) 2004-11-22 2010-01-19 Intelliject, Inc. Devices, systems and methods for medicament delivery
US7648482B2 (en) 2004-11-22 2010-01-19 Intelliject, Inc. Devices, systems, and methods for medicament delivery
WO2006057636A1 (fr) 2004-11-22 2006-06-01 Intelliject, Llc Dispositifs, systemes et procedes d'administration de medicaments
US10737028B2 (en) 2004-11-22 2020-08-11 Kaleo, Inc. Devices, systems and methods for medicament delivery
US7947017B2 (en) 2004-11-22 2011-05-24 Intelliject, Inc. Devices, systems and methods for medicament delivery
KR20070117543A (ko) 2005-01-24 2007-12-12 앤태어스 파머, 인코퍼레이티드 프리필 니들 조력 제트 주사기
GB2440039A (en) 2005-02-01 2008-01-16 Intelliject Llc Devices, systems and methods for medicament delivery
GB2424836B (en) 2005-04-06 2010-09-22 Cilag Ag Int Injection device (bayonet cap removal)
GB2425062B (en) 2005-04-06 2010-07-21 Cilag Ag Int Injection device
GB2427826B (en) * 2005-04-06 2010-08-25 Cilag Ag Int Injection device comprising a locking mechanism associated with integrally formed biasing means
US20110098656A1 (en) 2005-09-27 2011-04-28 Burnell Rosie L Auto-injection device with needle protecting cap having outer and inner sleeves
WO2007131013A1 (fr) 2006-05-03 2007-11-15 Antares Pharma, Inc. Injecteur de reconstitution à deux étages
US9144648B2 (en) 2006-05-03 2015-09-29 Antares Pharma, Inc. Injector with adjustable dosing
GB2438591B (en) 2006-06-01 2011-07-13 Cilag Gmbh Int Injection device
JP5535623B2 (ja) * 2006-06-30 2014-07-02 アッヴィ バイオテクノロジー リミテッド 自動注射装置
DK2125084T3 (da) * 2006-12-22 2011-05-16 Novo Nordisk As Afskærmelig nåleanordning med forspændt sikkerhedsskærm
AU2008226638B2 (en) * 2007-03-09 2013-03-28 Eli Lilly And Company Delay mechanism for automatic injection device
DE102007030327A1 (de) * 2007-06-29 2009-01-02 Tecpharma Licensing Ag Injektionsvorrichtung mit einer Feder für eine Nadelschutzhülse
US7713243B2 (en) * 2007-09-25 2010-05-11 Becton, Dickinson And Company Tip shield for needle stick prevention
WO2009114542A1 (fr) 2008-03-10 2009-09-17 Antares Pharma, Inc. Dispositif de sécurité pour injecteur
WO2009114762A1 (fr) 2008-03-13 2009-09-17 Becton, Dickinson And Company Ensemble aiguille de stylo de sécurité comportant un blindage pour des extrémités de patient et de non-patient
WO2009114777A1 (fr) 2008-03-13 2009-09-17 Becton, Dickinson And Company Ensemble aiguille de sécurité
ES2733497T3 (es) 2008-03-13 2019-11-29 Becton Dickinson Co Conjunto de seguridad de aguja de pluma con protección para el extremo opuesto al paciente
MX2010012691A (es) 2008-05-20 2011-03-30 Avant Medical Corp Star Sistema auto-inyector.
US8052645B2 (en) 2008-07-23 2011-11-08 Avant Medical Corp. System and method for an injection using a syringe needle
GB2460398A (en) * 2008-05-20 2009-12-02 Owen Mumford Ltd Auto-injector having a magnetic injection indicator and a needle sheath retainer
US8177749B2 (en) 2008-05-20 2012-05-15 Avant Medical Corp. Cassette for a hidden injection needle
US7811261B2 (en) 2008-06-02 2010-10-12 Sta-Med, Llc Needle cover assembly for a syringe
GB2461085B (en) 2008-06-19 2012-08-29 Cilag Gmbh Int Injection device
WO2010017285A2 (fr) 2008-08-05 2010-02-11 Antares Pharma, Inc. Injecteur à dosage multiple
GB2463034B (en) * 2008-08-28 2012-11-07 Owen Mumford Ltd Autoinjection devices
US9901681B2 (en) * 2008-09-18 2018-02-27 Becton, Dickinson And Company Medical injector with slidable sleeve activation
JP4806818B2 (ja) * 2008-11-17 2011-11-02 クリエートメディック株式会社 トロカール
GB0821492D0 (en) * 2008-11-25 2008-12-31 Team Holdings Uk Ltd Integrated auto-injector cartridge system
GB0823693D0 (en) * 2008-12-31 2009-02-04 Owen Mumford Ltd Autoinjector
US9044553B2 (en) 2009-03-13 2015-06-02 Eli Lilly And Company Apparatus for injecting a pharmaceutical with automatic syringe retraction following injection
KR101597672B1 (ko) 2009-03-20 2016-02-25 앤태어스 파머, 인코퍼레이티드 위험 약제 주사 장치
KR101721906B1 (ko) 2009-04-29 2017-03-31 애브비 바이오테크놀로지 리미티드 자동 주입 장치
ES2680668T3 (es) * 2009-10-16 2018-09-10 Janssen Biotech, Inc. Dispositivo de administración de fármacos activado con la palma de la mano
US9233213B2 (en) 2009-10-16 2016-01-12 Janssen Biotech, Inc. Palm activated drug delivery device
EP2512558A4 (fr) 2009-12-15 2014-08-13 Abbvie Biotechnology Ltd Poussoir de déclenchement amélioré pour dispositif d'injection automatique
UA110026C2 (uk) 2010-03-01 2015-11-10 Пристрій для автоматичного виконання ін'єкції з механізмом затримки, який включає в себе пересувальний елемент подвійного призначення
KR101850687B1 (ko) 2010-04-21 2018-04-20 애브비 바이오테크놀로지 리미티드 치료제의 제어된 전달을 위한 착용형 자동 주사 디바이스
US8162882B2 (en) 2010-06-23 2012-04-24 Sta-Med, Llc Automatic-locking safety needle covers and methods of use and manufacture
JP6165055B2 (ja) * 2010-06-28 2017-07-19 サノフィ−アベンティス・ドイチュラント・ゲゼルシャフト・ミット・ベシュレンクテル・ハフツング 自動注射器
EP2399635A1 (fr) 2010-06-28 2011-12-28 Sanofi-Aventis Deutschland GmbH Auto-injecteur
EP2399629A1 (fr) * 2010-06-28 2011-12-28 Sanofi-Aventis Deutschland GmbH Auto-injecteur
EP2399628A1 (fr) * 2010-06-28 2011-12-28 Sanofi-Aventis Deutschland GmbH Auto-injecteur
RU2573039C2 (ru) 2010-07-02 2016-01-20 Санофи-Авентис Дойчланд Гмбх Защитное устройство для предварительно заполненного шприца и инъекционное устройство
EP2460553A1 (fr) * 2010-12-02 2012-06-06 Debiotech S.A. Dispositif pour l'insertion d'aiguilles
GB201021717D0 (en) * 2010-12-22 2011-02-02 Owen Mumford Ltd Autoinjectors
AU2011354202A1 (en) * 2011-01-04 2013-07-18 Sanofi-Aventis Deutschland Gmbh Safety device for a pre-filled syringe and injection device
JP5864607B2 (ja) * 2011-01-04 2016-02-17 サノフィ−アベンティス・ドイチュラント・ゲゼルシャフト・ミット・ベシュレンクテル・ハフツング プレフィルドシリンジと注射デバイス用の安全デバイス
WO2012093072A1 (fr) * 2011-01-04 2012-07-12 Sanofi-Aventis Deutschland Gmbh Dispositif de sûreté pour une seringue pré-remplie, et dispositif d'injection
EP4245219A3 (fr) 2011-01-24 2023-11-01 AbbVie Biotechnology Ltd. Dispositifs d'injection automatique présentant des surfaces de préhension surmoulées
AU2012210170B2 (en) 2011-01-24 2016-09-29 Elcam Medical Agricultural Cooperative Association Ltd. Injector
PE20141543A1 (es) 2011-01-24 2014-11-23 Abbvie Biotechnology Ltd Extraccion de protectores de aguja desde jeringas y dispositivos de inyeccion automatica
US8939943B2 (en) 2011-01-26 2015-01-27 Kaleo, Inc. Medicament delivery device for administration of opioid antagonists including formulations for naloxone
US9173999B2 (en) 2011-01-26 2015-11-03 Kaleo, Inc. Devices and methods for delivering medicaments from a multi-chamber container
US8627816B2 (en) 2011-02-28 2014-01-14 Intelliject, Inc. Medicament delivery device for administration of opioid antagonists including formulations for naloxone
EP2489390A1 (fr) 2011-02-18 2012-08-22 Sanofi-Aventis Deutschland GmbH Mécanisme d'encliquetage
EP2489382A1 (fr) 2011-02-18 2012-08-22 Sanofi-Aventis Deutschland GmbH Auto-injecteur
EP2489389A1 (fr) 2011-02-18 2012-08-22 Sanofi-Aventis Deutschland GmbH Mécanisme d'encliquetage
EP2489380A1 (fr) 2011-02-18 2012-08-22 Sanofi-Aventis Deutschland GmbH Dispositif d'injection
EP2489387A1 (fr) 2011-02-18 2012-08-22 Sanofi-Aventis Deutschland GmbH Auto-injecteur
EP2489386A1 (fr) 2011-02-18 2012-08-22 Sanofi-Aventis Deutschland GmbH Auto-injecteur
EP2489385A1 (fr) 2011-02-18 2012-08-22 Sanofi-Aventis Deutschland GmbH Auto-injecteur
EP2489381A1 (fr) 2011-02-18 2012-08-22 Sanofi-Aventis Deutschland GmbH Auto-injecteur
EP2489388A1 (fr) 2011-02-18 2012-08-22 Sanofi-Aventis Deutschland GmbH Auto-injecteur
EP2489384A1 (fr) 2011-02-18 2012-08-22 Sanofi-Aventis Deutschland GmbH Auto-injecteur
US9956353B2 (en) * 2011-03-29 2018-05-01 Abbvie Inc. Shroud deployment in automatic injection devices
CA2833748C (fr) 2011-04-20 2019-07-16 Amgen Inc. Appareil auto-injecteur
WO2012166746A1 (fr) 2011-05-31 2012-12-06 Sta-Med, Llc Dispositifs de sécurité de prélèvement de sang et leurs procédés d'utilisation et de fabrication
US9220660B2 (en) 2011-07-15 2015-12-29 Antares Pharma, Inc. Liquid-transfer adapter beveled spike
US8496619B2 (en) 2011-07-15 2013-07-30 Antares Pharma, Inc. Injection device with cammed ram assembly
KR20140050753A (ko) 2011-08-31 2014-04-29 에스에이치엘 그룹 에이비 주사 장치
EP2572741A1 (fr) 2011-09-23 2013-03-27 Sanofi-Aventis Deutschland GmbH Dispositif d'administration de médicament et mécanisme d'actionnement pour un dispositif d'administration de médicament
WO2013130973A1 (fr) 2012-03-02 2013-09-06 Abbvie Inc. Dispositif d'apprentissage d'injection automatique
WO2013134244A2 (fr) 2012-03-06 2013-09-12 Antares Pharma, Inc. Ampoule-seringue à caractéristique de force de rupture
US9950125B2 (en) 2012-04-06 2018-04-24 Antares Pharma, Inc. Needle assisted jet injection administration of testosterone compositions
USD898908S1 (en) 2012-04-20 2020-10-13 Amgen Inc. Pharmaceutical product cassette for an injection device
USD808010S1 (en) 2012-04-20 2018-01-16 Amgen Inc. Injection device
WO2013169804A1 (fr) 2012-05-07 2013-11-14 Antares Pharma, Inc. Dispositif d'injection par jet assisté par une aiguille, présentant une force de déclenchement réduite
WO2014013594A1 (fr) * 2012-07-19 2014-01-23 テルモ株式会社 Instrument d'administration de liquide
JP6046721B2 (ja) * 2012-07-23 2016-12-21 テルモ株式会社 液体投与具
EP2727617A1 (fr) 2012-11-06 2014-05-07 Sanofi-Aventis Deutschland GmbH Auto-injecteur
EP2953672A1 (fr) * 2013-02-08 2015-12-16 Sanofi-Aventis Deutschland GmbH Dispositif de distribution de médicament avec protection d'aiguille
EP4349383A3 (fr) 2013-02-11 2024-06-19 Antares Pharma, Inc. Dispositif d'injection par jet assisté par aiguille ayant une force de déclenchement réduite
WO2014164786A1 (fr) 2013-03-11 2014-10-09 Madsen Patrick Injecteur de dose avec système à pignon
WO2014165136A1 (fr) 2013-03-12 2014-10-09 Antares Pharma, Inc. Seringues pré-remplies à volume constant et leurs trousses
KR20150119092A (ko) 2013-03-14 2015-10-23 일라이 릴리 앤드 캄파니 소형 자동 주사 장치에 적절한 지연 기구
WO2014159018A1 (fr) 2013-03-14 2014-10-02 Eli Lilly And Company Ensemble de déclenchement pour dispositif d'injection automatique
TWI580452B (zh) 2013-03-15 2017-05-01 安美基公司 用於注射器之匣盒、注射器及使用包括自動注射器及匣盒之設備之方法
JP6336564B2 (ja) 2013-03-15 2018-06-06 アムゲン・インコーポレーテッド 薬物カセット、自動注入器、および自動注入器システム
EP2781230B1 (fr) 2013-03-22 2019-08-21 TecPharma Licensing AG Dispositif de distribution de substances avec dispositif de signal
GB2515039B (en) 2013-06-11 2015-05-27 Cilag Gmbh Int Injection Device
GB2515032A (en) 2013-06-11 2014-12-17 Cilag Gmbh Int Guide for an injection device
GB2517896B (en) 2013-06-11 2015-07-08 Cilag Gmbh Int Injection device
GB2515038A (en) 2013-06-11 2014-12-17 Cilag Gmbh Int Injection device
US10994871B2 (en) * 2013-07-03 2021-05-04 Deka Products Limited Partnership Apparatus, system and method for fluid delivery
US11077965B2 (en) * 2013-07-03 2021-08-03 Deka Products Limited Partnership Apparatus, system and method for fluid delivery
US9649452B2 (en) 2013-12-10 2017-05-16 Becton, Dickinson And Company Active safety pen needle assembly
EP2883562B1 (fr) 2013-12-10 2016-08-17 Becton Dickinson and Company Ensemble aiguille de stylo sécurisé passif
JP6296840B2 (ja) * 2014-03-11 2018-03-20 テルモ株式会社 液体投与具
KR101448858B1 (ko) 2014-05-15 2014-10-13 송태섭 주사기용 바늘의 캡핑장치
US9517307B2 (en) 2014-07-18 2016-12-13 Kaleo, Inc. Devices and methods for delivering opioid antagonists including formulations for naloxone
CH710119A2 (de) * 2014-09-03 2016-03-15 Tecpharma Licensing Ag Injektionsvorrichtung mit einer Ablaufsteuerung.
CN104436369A (zh) * 2014-12-30 2015-03-25 江苏华阳电器有限公司 一种注射器隐针机构
CN107835700A (zh) 2015-06-30 2018-03-23 Kaleo公司 用于施用在预填充针筒内的药剂的自动注射器
GB2542202A (en) * 2015-09-14 2017-03-15 Consort Medical Plc Injection device
GB2545266B (en) 2015-12-11 2018-08-08 Oval Medical Tech Limited Autoinjector with retracting needle
JP7014797B2 (ja) 2016-12-23 2022-02-01 カレオ,インコーポレイテッド 乳児及び子供に薬物を送達するための薬物送達装置及び方法
CN106859811B (zh) * 2017-02-06 2018-05-22 浙江大学 电动有针注射器的自动扎针装置
CN110545863B (zh) * 2017-04-25 2021-06-01 群康生技股份有限公司 注射笔
CN107243108B (zh) * 2017-07-03 2024-02-06 玉环天来科技有限公司 上自毁护套机构
CN109317371A (zh) * 2018-12-08 2019-02-12 大连鑫鑫创世科技发展有限公司 一种电脑散热硅脂导热胶的注射装置及方法
US11167087B2 (en) 2019-08-09 2021-11-09 Kaleo, Inc. Devices and methods for delivery of substances within a prefilled syringe
KR102154125B1 (ko) * 2020-03-27 2020-09-09 (주)딥셀라이트 앰플 주사기
CN111939394B (zh) * 2020-08-25 2022-04-08 华中农业大学 一种注射器针头保护装置
EP4208220A1 (fr) * 2020-09-01 2023-07-12 West Pharmaceutical Services, Inc. Dispositif d'injection à multiples étages

Family Cites Families (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3638984C3 (de) * 1986-11-14 1993-11-18 Haselmeier Wilhelm Fa Injektionsgerät
DE3715337C2 (de) * 1986-11-14 1994-04-14 Haselmeier Wilhelm Fa Injektionsgerät
US5271744A (en) * 1991-04-29 1993-12-21 George C. Kramer System and method for rapid vascular drug delivery
US5201708A (en) * 1992-02-03 1993-04-13 Timothy A. Kershenstine Self-locking safety syringe
JP2723048B2 (ja) * 1994-06-24 1998-03-09 株式会社ニッショー 血液吸出器具
US5658259A (en) * 1995-10-19 1997-08-19 Meridian Medical Technologies, Inc. Dental cartridge assembly auto-injector with protective needle cover
US5609577A (en) * 1996-01-29 1997-03-11 Haber; Terry M. Automatically locking hypodermic needle hiding shield for a dose metering syringe
US6171276B1 (en) * 1997-08-06 2001-01-09 Pharmacia & Upjohn Ab Automated delivery device and method for its operation
SE9702872D0 (sv) * 1997-08-06 1997-08-06 Pharmacia & Upjohn Ab Automated delivery device and method for its operation
IE970782A1 (en) * 1997-10-22 1999-05-05 Elan Corp An improved automatic syringe
US7029461B2 (en) * 1999-11-04 2006-04-18 Tyco Healthcare Group Lp Safety shield for medical needles
FR2801795B1 (fr) * 1999-12-07 2002-07-05 Plastef Investissements Dispositif de support de securite pour une seringue et ensemble d'un tel dispositif et d'une seringue
SE515405C2 (sv) * 2000-01-25 2001-07-30 Gudmar Olovson Nålskyddsarrangemang
GB0003790D0 (en) * 2000-02-18 2000-04-05 Astrazeneca Uk Ltd Medical device
US7004929B2 (en) * 2002-03-29 2006-02-28 Mdc Investment Holdings, Inc. Safety pre-filled cartridge injector
EP1572270A1 (fr) * 2002-11-25 2005-09-14 Tecpharma Licensing AG Dispositif d'injection pourvu d'une protection d'aiguille
JP4377880B2 (ja) * 2002-11-25 2009-12-02 テクファーマ・ライセンシング・アクチェンゲゼルシャフト 薬剤を自動的に注射するための装置
US6939330B1 (en) * 2002-12-12 2005-09-06 Medsolve Llc Syringe insertion system
DE10339794A1 (de) * 2003-08-28 2005-04-07 Tecpharma Licensing Ag Verabreichungsvorrichtung mit einer Schutzkappenabziehvorrichtung und einer Nadelschutzhülsenblockiereinrichtung
CH696421A5 (de) * 2003-12-18 2007-06-15 Tecpharma Licensing Ag Autoinjektor mit Arretierung des Wirkstoffbehälters.
US6989001B2 (en) * 2004-05-28 2006-01-24 Huang-Chuan Chen Breakable syringe with a safety sleeve

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
See references of WO2004047892A1 *

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AU2003280270B2 (en) 2008-01-24
WO2004047892A1 (fr) 2004-06-10
US7361160B2 (en) 2008-04-22
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CN100506305C (zh) 2009-07-01
US20080071225A1 (en) 2008-03-20

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