EP1523312A1 - Elevation du taux d' heme oxygynase avec des derives de la rheine - Google Patents
Elevation du taux d' heme oxygynase avec des derives de la rheineInfo
- Publication number
- EP1523312A1 EP1523312A1 EP03750824A EP03750824A EP1523312A1 EP 1523312 A1 EP1523312 A1 EP 1523312A1 EP 03750824 A EP03750824 A EP 03750824A EP 03750824 A EP03750824 A EP 03750824A EP 1523312 A1 EP1523312 A1 EP 1523312A1
- Authority
- EP
- European Patent Office
- Prior art keywords
- rhein
- use according
- diacerein
- derivative
- treatment
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Withdrawn
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- A61P37/02—Immunomodulators
- A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P39/00—General protective or antinoxious agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
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- Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Immunology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Epidemiology (AREA)
- Emergency Medicine (AREA)
- Toxicology (AREA)
- Transplantation (AREA)
- Pain & Pain Management (AREA)
- Rheumatology (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR0209340A FR2842738B1 (fr) | 2002-07-23 | 2002-07-23 | Utilisation d'une rheine pour la preparation d'un medicament pour le traitement de l'inflammation chronique, la prevention et le traitement du rejet des transplantations d'organes et de tissus |
| FR0209340 | 2002-07-23 | ||
| PCT/FR2003/002286 WO2004010990A1 (fr) | 2002-07-23 | 2003-07-18 | Elevation du taux d’ heme oxygenase avec des derives de la rheine |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| EP1523312A1 true EP1523312A1 (fr) | 2005-04-20 |
Family
ID=30011416
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| EP03750824A Withdrawn EP1523312A1 (fr) | 2002-07-23 | 2003-07-18 | Elevation du taux d' heme oxygynase avec des derives de la rheine |
Country Status (9)
| Country | Link |
|---|---|
| US (1) | US20060058392A1 (ja) |
| EP (1) | EP1523312A1 (ja) |
| JP (1) | JP2005538098A (ja) |
| AU (1) | AU2003269037A1 (ja) |
| CA (1) | CA2493074A1 (ja) |
| FR (1) | FR2842738B1 (ja) |
| IL (1) | IL166434A0 (ja) |
| MX (1) | MXPA05000904A (ja) |
| WO (1) | WO2004010990A1 (ja) |
Families Citing this family (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| TWI473610B (zh) * | 2008-10-28 | 2015-02-21 | Twi Biotechnology Inc | 包含雙醋瑞因（ｄｉａｃｅｒｅｉｎ）之醫藥組合物 |
| AR078101A1 (es) * | 2009-08-20 | 2011-10-12 | Anchen Lab Inc | Metodos para diagnosticar la diabetes y determinar la eficacia de tratamientos |
| US8652540B2 (en) | 2012-06-04 | 2014-02-18 | Hong Kong Baptist University | Method of using rhein for treating fibrotic conditions and tumors |
| TWI743047B (zh) * | 2015-08-17 | 2021-10-21 | 安成生物科技股份有限公司 | 使用雙醋瑞因或其類似物抑制asc表現、nlrp3表現、以及/或nlrp3發炎體複合物的形成之方法 |
| TW201739448A (zh) * | 2016-05-06 | 2017-11-16 | 安成生物科技股份有限公司 | 用於治療及/或預防血液相關疾病之方法及配方 |
| US10675260B2 (en) * | 2017-01-19 | 2020-06-09 | Twi Biotechnology, Inc. | Methods and pharmaceutical compositions for preventing or treating immunoinflammatory dermal disorders |
Family Cites Families (15)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ZA761627B (en) * | 1976-03-16 | 1978-01-25 | C Friedmann | Improvements in or relating to the treatment of arthritis |
| JPH0374326A (ja) * | 1989-08-17 | 1991-03-28 | Tsumura & Co | ケミルミネッセンス抑制剤 |
| CA2132690A1 (en) * | 1994-09-22 | 1996-03-23 | Dean Willis | Control and modulation of inflammatory response in humans in need of such control and modulation |
| US5652265A (en) * | 1995-03-29 | 1997-07-29 | Wisconsin Alumni Research Foundation | Production of rhein and rhein derivatives |
| IT1283771B1 (it) * | 1996-07-31 | 1998-04-30 | Medidom Lab | Procedimento per la preparazione di derivati della reina |
| JP4049406B2 (ja) * | 1996-10-15 | 2008-02-20 | 正規 小菅 | 津液改善剤及びそれを含有する経口投与用組成物 |
| ATE352556T1 (de) * | 1997-04-11 | 2007-02-15 | Sangstat Medical Corp | Zytomodulierende lipophile peptide zur modulation der immunsystemaktivität und hemmung von entzündungen |
| CN1086289C (zh) * | 1997-09-30 | 2002-06-19 | 中国人民解放军肾脏病研究所 | 大黄酸或大黄酸盐在制备治疗糖尿病肾病药中的用途 |
| DE69941966D1 (de) * | 1998-02-13 | 2010-03-11 | Nutramax Lab Inc | Mittel und Verfahren zum Schutz, zur Behandlung und Reparatur von Bindegewebe |
| WO2000012118A2 (en) * | 1998-08-28 | 2000-03-09 | President And Fellows Of Harvard College | Inhibiting cardiomyocyte death |
| JP2000119182A (ja) * | 1998-10-09 | 2000-04-25 | Nippon Chemiphar Co Ltd | ヘムオキシゲナーゼ誘導促進剤 |
| CA2355066A1 (en) * | 1998-12-17 | 2000-06-22 | Sangstat Medical Corporation | Extending graft survival by heme oxygenase-i expression induced immunomodulation |
| JP3860752B2 (ja) * | 2000-03-17 | 2006-12-20 | 利男 田中 | ヘムオキシゲナーゼ−１の誘導または誘導増強剤 |
| US6610750B1 (en) * | 2000-09-15 | 2003-08-26 | Laboratoires Negma | Treatment of osteoarthritis |
| US20020128317A1 (en) * | 2001-01-23 | 2002-09-12 | Laboratories Negma | Treatment of pathological conditions characterized by an increased IL-1 level |
-
2002
- 2002-07-23 FR FR0209340A patent/FR2842738B1/fr not_active Expired - Fee Related
-
2003
- 2003-07-18 WO PCT/FR2003/002286 patent/WO2004010990A1/fr active Application Filing
- 2003-07-18 AU AU2003269037A patent/AU2003269037A1/en not_active Abandoned
- 2003-07-18 MX MXPA05000904A patent/MXPA05000904A/es not_active Application Discontinuation
- 2003-07-18 EP EP03750824A patent/EP1523312A1/fr not_active Withdrawn
- 2003-07-18 US US10/522,035 patent/US20060058392A1/en not_active Abandoned
- 2003-07-18 CA CA002493074A patent/CA2493074A1/fr not_active Abandoned
- 2003-07-18 JP JP2004523858A patent/JP2005538098A/ja active Pending
-
2005
- 2005-01-20 IL IL16643405A patent/IL166434A0/xx unknown
Non-Patent Citations (5)
| Title |
|---|
| DATABASE CHEMABS CHEMICAL ABSTRACTS SERVICE, COLUMBUS, OHIO, US; Database accession no. 1989:624957 * |
| DATABASE EMBASE [online] ELSEVIER SCIENCE PUBLISHERS, AMSTERDAM, NL; 1989, LU M ET AL: "Biochemical study of Chinese rhubarb. xxx. Immunosuppressive effects of anthraquinone derivatives", Database accession no. EMB-1989263837 * |
| JOURNAL OF CHINA PHARMACEUTICAL UNIVERSITY 1989 CN, vol. 20, no. 4, 1989, pages 223 - 226, ISSN: 1000-5048 * |
| LU MING ET AL.: "Biochemical study of Chinese rhubarb XXX.", ZHONGGUO YAOKE DAYUE XUEBAO, 1989, Ohio * |
| See also references of WO2004010990A1 * |
Also Published As
| Publication number | Publication date |
|---|---|
| AU2003269037A1 (en) | 2004-02-16 |
| IL166434A0 (en) | 2006-01-15 |
| JP2005538098A (ja) | 2005-12-15 |
| MXPA05000904A (es) | 2005-03-23 |
| FR2842738B1 (fr) | 2006-02-10 |
| WO2004010990A1 (fr) | 2004-02-05 |
| US20060058392A1 (en) | 2006-03-16 |
| CA2493074A1 (fr) | 2004-02-05 |
| FR2842738A1 (fr) | 2004-01-30 |
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| RIN1 | Information on inventor provided before grant (corrected) |
Inventor name: FICHEUX, HERVE Inventor name: PROVVEDINI, DIEGO Inventor name: CHARBIT, SUZY Inventor name: SCHUTZE, FRANCOIS |
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| RTI1 | Title (correction) |
Free format text: USE OF A RHEIN FOR TREATING TRANSPLANT REJECTION VIA RISE IN THE RATE OF HEME OXYGENASE |
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