EP1412261B1 - Bouchon de fermeture destine a des flacons de perfusion ou de transfusion - Google Patents

Bouchon de fermeture destine a des flacons de perfusion ou de transfusion Download PDF

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Publication number
EP1412261B1
EP1412261B1 EP02754832A EP02754832A EP1412261B1 EP 1412261 B1 EP1412261 B1 EP 1412261B1 EP 02754832 A EP02754832 A EP 02754832A EP 02754832 A EP02754832 A EP 02754832A EP 1412261 B1 EP1412261 B1 EP 1412261B1
Authority
EP
European Patent Office
Prior art keywords
closure cap
closure
overcap
latching
cap according
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
EP02754832A
Other languages
German (de)
English (en)
Other versions
EP1412261A1 (fr
Inventor
Albert Louis Victor Jozef Claessens
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Helvoet Pharma NV
Datwyler Pharma Packaging Belgium NV
Original Assignee
Helvoet Pharma NV
Helvoet Pharma Belgium NV
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Helvoet Pharma NV, Helvoet Pharma Belgium NV filed Critical Helvoet Pharma NV
Publication of EP1412261A1 publication Critical patent/EP1412261A1/fr
Application granted granted Critical
Publication of EP1412261B1 publication Critical patent/EP1412261B1/fr
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

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Classifications

    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B65—CONVEYING; PACKING; STORING; HANDLING THIN OR FILAMENTARY MATERIAL
    • B65D—CONTAINERS FOR STORAGE OR TRANSPORT OF ARTICLES OR MATERIALS, e.g. BAGS, BARRELS, BOTTLES, BOXES, CANS, CARTONS, CRATES, DRUMS, JARS, TANKS, HOPPERS, FORWARDING CONTAINERS; ACCESSORIES, CLOSURES, OR FITTINGS THEREFOR; PACKAGING ELEMENTS; PACKAGES
    • B65D51/00—Closures not otherwise provided for
    • B65D51/18—Arrangements of closures with protective outer cap-like covers or of two or more co-operating closures
    • B65D51/20—Caps, lids, or covers co-operating with an inner closure arranged to be opened by piercing, cutting, or tearing
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61J—CONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
    • A61J1/00—Containers specially adapted for medical or pharmaceutical purposes
    • A61J1/14—Details; Accessories therefor
    • A61J1/1412—Containers with closing means, e.g. caps
    • A61J1/1418—Threaded type
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61J—CONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
    • A61J1/00—Containers specially adapted for medical or pharmaceutical purposes
    • A61J1/14—Details; Accessories therefor
    • A61J1/1412—Containers with closing means, e.g. caps
    • A61J1/1425—Snap-fit type
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61J—CONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
    • A61J1/00—Containers specially adapted for medical or pharmaceutical purposes
    • A61J1/14—Details; Accessories therefor
    • A61J1/18—Arrangements for indicating condition of container contents, e.g. sterile condition
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B65—CONVEYING; PACKING; STORING; HANDLING THIN OR FILAMENTARY MATERIAL
    • B65D—CONTAINERS FOR STORAGE OR TRANSPORT OF ARTICLES OR MATERIALS, e.g. BAGS, BARRELS, BOTTLES, BOXES, CANS, CARTONS, CRATES, DRUMS, JARS, TANKS, HOPPERS, FORWARDING CONTAINERS; ACCESSORIES, CLOSURES, OR FITTINGS THEREFOR; PACKAGING ELEMENTS; PACKAGES
    • B65D51/00—Closures not otherwise provided for
    • B65D51/002—Closures to be pierced by an extracting-device for the contents and fixed on the container by separate retaining means
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61J—CONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
    • A61J1/00—Containers specially adapted for medical or pharmaceutical purposes
    • A61J1/14—Details; Accessories therefor
    • A61J1/1406—Septums, pierceable membranes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61J—CONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
    • A61J1/00—Containers specially adapted for medical or pharmaceutical purposes
    • A61J1/14—Details; Accessories therefor
    • A61J1/1468—Containers characterised by specific material properties
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B65—CONVEYING; PACKING; STORING; HANDLING THIN OR FILAMENTARY MATERIAL
    • B65D—CONTAINERS FOR STORAGE OR TRANSPORT OF ARTICLES OR MATERIALS, e.g. BAGS, BARRELS, BOTTLES, BOXES, CANS, CARTONS, CRATES, DRUMS, JARS, TANKS, HOPPERS, FORWARDING CONTAINERS; ACCESSORIES, CLOSURES, OR FITTINGS THEREFOR; PACKAGING ELEMENTS; PACKAGES
    • B65D2251/00—Details relating to container closures
    • B65D2251/0003—Two or more closures
    • B65D2251/0006—Upper closure
    • B65D2251/0015—Upper closure of the 41-type
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B65—CONVEYING; PACKING; STORING; HANDLING THIN OR FILAMENTARY MATERIAL
    • B65D—CONTAINERS FOR STORAGE OR TRANSPORT OF ARTICLES OR MATERIALS, e.g. BAGS, BARRELS, BOTTLES, BOXES, CANS, CARTONS, CRATES, DRUMS, JARS, TANKS, HOPPERS, FORWARDING CONTAINERS; ACCESSORIES, CLOSURES, OR FITTINGS THEREFOR; PACKAGING ELEMENTS; PACKAGES
    • B65D2251/00—Details relating to container closures
    • B65D2251/0003—Two or more closures
    • B65D2251/0068—Lower closure
    • B65D2251/009—Lower closure of the 51-type

Definitions

  • the invention relates to a closure cap according to the features of the preamble of claim 1.
  • the invention has the object to form a generic closure with respect to the acquisition of a pre-allocation advantageous as treatment-accessible mounting unit.
  • a generic closure increased use value is achieved: This is due to the creation of a assembly unit, both in terms of the cohesion of the closure forming parts as well as in terms of a defined, variable Vorrast. This provides area clearance for measures to sterilize the closure.
  • the overflowing displacement of the overcap to the rest of the stroke leads to a defined form-fitting mounting of the cap on the bottle neck.
  • the seal member is in mechanically sufficient strength associated with its carrier, namely the cap, respectively caught on it. Again, the outer, free-presenting areas are best accessible for the mentioned treatment. This also applies to the underside of the overarching overcap.
  • the distance defining, reversible detent position has as it were a threshold, which releases the further assembly stroke of the overcap only when the intercepting undergrip of the cap has taken place on the bottleneck. It builds up an abutment. It lowers the wall, as already indicated, like a locking bar on the anchoring zone of the cap.
  • closure cap and the sealing member are made in two-component injection molding.
  • the adhesive power to be obtained therefrom or adjusted was found to be sufficient; In any case, the usual mechanical stresses, eg. In the context of the above-mentioned sterilization, transport, the passage of the filling paths, the migration in sorting lines, etc. are not sufficient to reach.
  • the assignment can also be such that a loosening is intentionally opened, for example, in order to separate in terms of type.
  • the closure cap is injection molded over the relatively soft, preformed sealing member. That leads to an effect of even independent significance: It comes namely because the seal member is due to shrinkage under elastic bias against the cap.
  • the closure cap associated with a closure cap blanket, has a latching configuration for reversible latching with the latching nose of the overcap.
  • the formation of the Rastausformung, associated with the cap cover creates with respect to the preassembled unit a maximum surface free space for sterilization. Specifically, the Rastausformung is arranged in a cross section below the cap cover, ie close to the ceiling.
  • the overcap has an overcap cover over the piercing area.
  • the accessibility of the piercing region required by use results from simple means in that a tear-off tab extending to the outer edge of the overcap blanket is formed in the overcap blanket by a weakening line.
  • the peripheral gripping approach here usually has a separation point, advantageously forming the access for the interior of the unit located in Vorrast.
  • two diametrically opposed, each up to a central region of the cap cover reaching tear-off tabs are formed.
  • a tear-open tab is assigned in each case to a piercing region which peripherally surrounds the closure cap blanket.
  • the piercing areas are as it were arranged island-like distributed in the ceiling field. It is further provided that the overcap is secured against rotation on the closure cap.
  • the rotational securing is achieved by vertical ribs formed on the inside of the cylinder wall of the overcap, which engage in corresponding vertical grooves of the closure cap.
  • the vertical grooves are the indicated specifications.
  • the relevant embodiment is characterized in that a vertical groove on the cap is mitge strict by the separation region between two circular segment-like Untergreifzept. Further, an advantageous embodiment is that the vertical groove continues up to the top of the cap cover, leaving a residue of the wall of the cap. The residue is due to a weak frustoconical transition of the wall of the cap to the cap cover.
  • an advantageous variant of the subject invention is finally that the sealing element ends at a radial distance to the inside of the annular wall of the closure cap.
  • a peripheral, circumferential annular gap can be easily taken into account in terms of manufacturing technology.
  • the local non-contact assignment to the inside is applicable if the described clamping voltage in this area should not be used and the minimization of the mutual adhesive surfaces is wanted.
  • the radial distance extending to the top of the closure cap can be used to pry out the sealing part for sorted separation.
  • the sealing part can be levered out of the shell like an oyster.
  • the illustrated, non-metallic closure V consists of a nestable Doppelkappe with a captured captive seal part. 1
  • the sealing member 1 is made of thermoplastic rubber (TPE) and is basically disc-shaped. Its edge 2 is thickening going against a bottleneck 3.
  • TPE thermoplastic rubber
  • a usable as an infusion or transfusion bottle 4 is made of glass.
  • the free end of the bottle neck 3 widens radially outward into a bead 5. It provides an undercut flank 6. This serves for an undercut under the actual closure cap 7 of the closure V.
  • the overcap covering it (7) bears the reference numeral 8.
  • the widened by the bead 5 end face 9 is designed rotationally symmetrical sloping roof-like.
  • the longer flank of the sloping roof slopes outwards.
  • the gable is rounded convex with connection to the mouth 10 of the neck 3 of a shorter, steeper sloping flank.
  • the mouth 10 facing the underside of the sealing part 1 is recessed planar.
  • the recess bears the reference numeral 11.
  • existing cap 7 is like the material-same overcap 8 pot-shaped shape.
  • the former sets this Sealing part 1 on the outside surrounding shell part, consisting of a substantially flat in the center cap cover 12.
  • The goes into an annular wall 13 on.
  • Ceiling 12 and ring wall 13 connect at an angle of more than 90 ° to each other; based on the corner as apex, this angle includes about 110 °.
  • the approach is denoted by a and the part by b. They are of equal leg length.
  • the annular wall 13 continues towards its free, lower end in Untergreifzept 14.
  • the circumferential direction of the cap 7 following, it is a wreath circular segment-like design, ausfedercopyer single tongues with excellent restoring force.
  • the curve also has a stabilizing effect.
  • the sub-gripping means is concretely an integrally formed, flaschenhals press exposed Rastwulst 15. These Rastwülste 15 snap anchoring under the undercut edge 6 of the bottle neck 3.
  • the edge courses of the parts 6 and 15 are coordinated. They extend approximately at an angle of about 40 ° outwards rising to a horizontal.
  • the individual gripping tongues 14 freely intersecting separation areas are realized as longitudinal slots 16 of the annular wall 13.
  • the slot bottom 16 of the longitudinal slots 16 terminates approximately at the same level as the exposed ridge of the end face 9 of the bottle neck 3.
  • the cap blanket 12 leaves pierceable areas.
  • the corresponding piercing region 17 lies in the center of the closure V, this in the form of a circular hole 18 whose radius point intersects the longitudinal center axis xx of the basically rotationally symmetrical closure V.
  • the central piercing area is embodied in the version shown in FIG. 9. Otherwise, the structure is identical to the basic version, starting with Fig.1.
  • the reference numbers are applied analogously, this partly without textile repetitions.
  • the basic version as clearly shown in FIG. 6, provides for two such piercing regions 17 in the closure cap 12.
  • the sealing member 1 protrudes with a cavity-filling portion of rubber-like substance in the respective, the piercing region 17 circumscribing hole 18th
  • the hole 18 can also be locked by a corresponding filling projection from the bottom or inside of the ceiling 19 of the overcap 8 cavity-filling protrudes into the opening or the hole 18.
  • the sealing part 1 does not have the disk-like packing 20 arranged on its outside.
  • the sealing part 1 is caught on the closure cap 7, the sealing part 1 being exposed to the outside of the closure cap 7 in the circumference of the piercing region 17.
  • Exposed means or includes, leaving a practicable pierceability, so that a top remaining remaining cuticle functionally still under this term to understand.
  • Cap 7 and sealing part 1 are produced in a two-component injection molding process.
  • the prefabricated, relatively softer injection molded part seal 1 is introduced with shaping in the injection / mold and molded with the relatively harder, the cap 7 resulting material. It In this case comes to the mentioned catching of the parts 1, 7 together, wherein the adhesion of the masses to each other can be adjusted so that the seal member 1 without sticking to the self-supporting hard body, ie cap 7, can be solved.
  • This docking position is defined by a first, reversible detent position with an axial distance y between the inside of the top 19 of the overcap 8 and the top of the closure cap 12 having the piercing region or portions 17.
  • This first reversible detent position is shown in the drawing I indicated.
  • Such a compiled unit 1/7/8 is immune to common mechanical loads, ie this preassembled unit can be promoted, sort, but above all, if necessary, perform the usual sterilization process.
  • the parts 7 and 8 are not yet nested and also left on the left in the area of the cap blanket 12 openings 21 under tear-off tabs 22 the space at a distance y reach.
  • the defined by locking distance y leaves recognizable the lower lugs 14 free-standing and fully capable of springing.
  • the shutter V is placed on the bottle neck 3.
  • the compensating lower engagement tongues 14 overflow the larger-diameter bulge 5 of the bottle neck 3, until finally the locking bulges 15 undercut the undercut surface 6.
  • the latching force holding the parts 7 and 8 at a distance y is set up with regard to an insurmountable threshold in such a way that the overcap 8 on the jacket wall of the closure cap 7 always comes after the described anchoring for further overflowing.
  • the procedure is such that the closure cap 7 has a detent formation 23.
  • This is preferably located as a circumferential groove on the outside of the annular wall 13, and lying near the cap cover 12, more precisely by below a occupied by the ceiling 12 cross-sectional plane of the closure V.
  • the corresponding counter-locking means provides a detent 24 on the inside of a cylinder wall 25 of the cup-shaped overcap. 8
  • the outside of the annular wall 13 and the inside of the cylinder wall 25 are roughened from the slot bottom 16 'of the longitudinal slots 16 to the locking lug 24 out. It is an ordered, form-fitting roughness in the form of a horizontally oriented tooth structure. Specifically, the structural details in such a way that the cap 7 in the circumferential direction of the circular segment-like sub-tabs 14 has outside Rastausformungen 27 in the form of depressions. In the grip on the inside of the cylinder wall 25 formed locking projections 28 in the form of ribs. The washboard-like contour can be seen in detail in the drawings.
  • the latching projections 28 have a lower radially oriented standing height than the latching noses 24.
  • the desired separation crack is favored by a weakening line 29. It is a top-side, notch-like trench guide, the trench bottom can be a fraction of a material bridge. In the area of the peripheral openings 21, even this area is broken through, so that the scribing can be facilitated.
  • the cantilever need not go beyond the general diameter of the overcap 8, if, as shown, in this end region, the shell wall of the same is flattened.
  • the corresponding fillet bears the reference numeral 30.
  • the overcap 8 is kept secured against rotation on the cap 7, which naturally does not require such a measure at a centrally located piercing portion 17 of the closure V and diametrically continuous tear tab 22.
  • the rotation lock is achieved by a on the cylinder wall 25 of the overcap 8 on the inside formed vertical rib 31.
  • two, diametrically formed opposite each other, axially oriented vertical ribs 31 are integrally formed.
  • the spatial assignment of the holes 18 to the locking engagement spaces is such that the desired full coverage of the holes 18 is given by the pull tabs 32 catching them.
  • the correct plug alignment can be practically felt by a slight rotational movement of the overcap 8 to the cap 7 out.
  • the unused lock-in rooms 16/32 can be locked on the input side. In the case of a centrally located hole 19, however, such a provision is not necessary.
  • Fig. 14 shows a specification in that the injection is made via one of two special holes 34 close to the edge, the other acting as a vent.
  • the holes 34 placed in a diametrical one of the cap cover 12 have only a fraction of the clear diameter of the holes 20 forming the packing 20. The ratio is 1: 6.
  • the holes 18 and 34 are each circular. They can be cylindrical, frustoconical or undercut.
  • the further variant of the closure V shown in FIG. 15 corresponds structurally to the basic version described in detail.
  • the reference numbers are applied analogously, in part without textual repetitions of the version readable to the basic version.
  • the deviating embodiment consists in that the substantially disc-shaped sealing element 1 now ends peripherally at a radial distance z from the inside of the annular wall 13 of the closure cap 7.
  • the substantially cylindrical edge 35 of the sealing element 1 is contact-free in front of the inside 36 of the annular wall 13 circumscribing it.
  • the fully circumferential annular gap formed in this way bears the reference numeral 37.
  • the annular gap 37 is only rudimentary. It extends only over a fraction of the shell-forming, vertical length of the annular wall 13, namely until shortly after the longitudinal slot base 16 'going.
  • annular gap 37 tapers towards the ceiling side gap reason.
  • This gap bottom is proportionately provided by the other, designated b part of the cap 7.
  • the slot bottom is recognizable realized as a non-contact zone between the sealing part 1 and the annular wall 13 and ceiling 12.
  • the annular gap 37 can be used in the sense that it forms a clamping-tension lock between the sealing part 1 and the closure cap 7.
  • the annular gap 37 is dimensioned in the radial direction so that it does not become clogged after the described shrinkage process. This leaves an access for the attachment of a lifting tool, for example, in the sense of a desired sorted separation of the closure V forming parts.
  • the means are applied as explained above. If, in a modification of the described piercing region, the hole 18 is not occupied by a filling body 20 of the sealing part 1, it is possible in return to proceed from the overcap blanket 19 or, as shown, from the underside of the tear-off tab 22 that occupies the hole.
  • a projection may of course be cylindrical or frusto-conical. In the latter case, then the hole 18 is designed adapted, so funnel-shaped. In the back of the projection provided by the overcap 8, this can have a dent from the top.

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  • Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Mechanical Engineering (AREA)
  • Closures For Containers (AREA)
  • Medical Preparation Storing Or Oral Administration Devices (AREA)
  • Infusion, Injection, And Reservoir Apparatuses (AREA)

Claims (17)

  1. Capuchon de fermeture (V) pour flacons de perfusion ou de transfusion, comportant une partie d'étanchéité (1) en caoutchouc adaptée sur le col de flacon (3), le capuchon de fermeture (7) étant configuré en une pièce de saisie par le dessous, soutenant un bourrelet (5), sur le col de flacon (3) et un capot (8) étant prévu pour l'attache par complémentarité de forme du capuchon de fermeture (7) sur le col de flacon (3), dans lequel, par ailleurs, la partie d'étanchéité (1) est capturée sur le capuchon de fermeture (7), est libre vers l'extérieur du capuchon de fermeture (7) dans une zone de perforation et le capot (8) surmontant également la zone de perforation (17) dans une première position d'encliquetage (I) réversible à une distance axiale (y) par rapport à la zone de perforation (17) peut être fixé sur le capuchon de fermeture (7) et dans lequel, par ailleurs, le capuchon de fermeture (7) présente, dans le sens périphérique, des languettes de saisie par le dessous (14) en forme de segments de cercle, munies d'un bourrelet d'encliquetage (15) et constituant la saisie par le dessous, et la paroi cylindrique (25) du capot (8) présentant un ergot d'encliquetage (24) pour la saisie d'encliquetage par le dessus du capuchon de fermeture (7) sur son extrémité inférieure libre, caractérisé en ce que les languettes de saisie par le dessous (14) présentent des creux d'encliquetage (27) côté extérieur pour un encliquetage avec le capot (8).
  2. Capuchon de fermeture selon la revendication 1, caractérisé en ce que le capuchon de fermeture (7) et la partie d'étanchéité (1) sont fabriqués avec un procédé d'injection à deux composants.
  3. Capuchon de fermeture selon la revendication 1 ou 2, caractérisé en ce que la partie d'étanchéité (1) est sous serrage élastique contre le capuchon de fermeture (7).
  4. Capuchon de fermeture selon l'une quelconque des revendications 1 à 3, caractérisé en ce que des parties d'encliquetage en saillie (28) sont formées sur la paroi cylindrique (25) du capot (8).
  5. Capuchon de fermeture selon la revendication 4, caractérisé en ce que l'ergot d'encliquetage (24) de la paroi cylindrique (25) dépasse des parties d'encliquetage en saillie (28).
  6. Capuchon de fermeture selon l'une quelconque des revendications 1 à 5, caractérisé en ce que le capuchon de fermeture (7), affecté à un recouvrement (12) du capuchon de fermeture, présente un creux d'encliquetage (23) pour l'encliquetage réversible avec l'ergot d'encliquetage (24) du capot (8).
  7. Capuchon de fermeture selon la revendication 6, caractérisé en ce que le creux d'encliquetage (23) est disposé dans une section transversale sous le recouvrement (12) du capuchon de fermeture.
  8. Capuchon de fermeture selon l'une quelconque des revendications 1 à 7, caractérisé en ce que le capot (8) présente un recouvrement (19) du capot surmontant aussi la zone de perforation (17).
  9. Capuchon de fermeture selon l'une quelconque des revendications 1 à 8, caractérisé en ce que, dans le recouvrement (19) du capot, un amincissement (29) forme une éclisse de déchirure (22) s'étendant jusqu'au bord extérieur du recouvrement (19) du capot.
  10. Capuchon de fermeture selon la revendication 9, caractérisé en ce qu'il y a deux éclisses de déchirure (22) diamétralement opposées, arrivant chacune jusqu'à une zone centrale du recouvrement (19) du capot.
  11. Capuchon de fermeture selon l'une quelconque des revendications 9 ou 10, caractérisé en ce qu'une éclisse de déchirure (22) est dans chaque cas affectée à une zone de perforation (17) entourée, à la périphérie, par le recouvrement (12) du capuchon de fermeture.
  12. Capuchon de fermeture selon l'une quelconque des revendications 1 à 11, caractérisé en ce que le capot (8) du capuchon de fermeture (7) est bloqué en rotation.
  13. Capuchon de fermeture selon la revendication 12, caractérisé en ce que la sécurité anti-rotation est obtenue par des nervures verticales (31) formées sur le côté intérieur de la paroi cylindrique (25) du capot (8) qui s'engagent dans les rainures verticales (32) correspondantes du capuchon de fermeture (7).
  14. Capuchon de fermeture selon la revendication 13, caractérisé en ce qu'une rainure verticale (32) est formée en même temps sur le capuchon de fermeture (7) par la zone de séparation entre deux languettes de saisie par le dessous (14) en forme de segments de cercle.
  15. Capuchon de fermeture selon l'une quelconque des revendications 13 ou 14, caractérisé en ce que la rainure verticale (32) se poursuit jusqu'au côté supérieur du recouvrement (12) du capuchon de fermeture, en laissant une partie restante (33) de la paroi annulaire (13) du capuchon de fermeture (7).
  16. Capuchon de fermeture selon l'une quelconque des revendications 1 à 15, caractérisé par un passage faiblement tronconique entre la paroi du capuchon de fermeture (7) et le recouvrement (12) du capuchon de fermeture.
  17. Capuchon de fermeture selon l'une quelconque des revendications 1 à 16, caractérisé en ce que l'élément d'étanchéité (1) se termine à une distance radiale (z) par rapport au côté intérieur (36) de la paroi annulaire (13) du capuchon de fermeture (7).
EP02754832A 2001-08-03 2002-07-05 Bouchon de fermeture destine a des flacons de perfusion ou de transfusion Expired - Lifetime EP1412261B1 (fr)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
DE10138191 2001-08-03
DE2001138191 DE10138191B4 (de) 2001-08-03 2001-08-03 Verschluss für Infusions- oder Transfusionsflaschen
PCT/EP2002/007452 WO2003013972A1 (fr) 2001-08-03 2002-07-05 Bouchon de fermeture destine a des flacons de perfusion ou de transfusion

Publications (2)

Publication Number Publication Date
EP1412261A1 EP1412261A1 (fr) 2004-04-28
EP1412261B1 true EP1412261B1 (fr) 2006-06-21

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US (1) US20040217082A1 (fr)
EP (1) EP1412261B1 (fr)
JP (1) JP2004536686A (fr)
CN (1) CN1274561C (fr)
DE (2) DE10138191B4 (fr)
WO (1) WO2003013972A1 (fr)

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WO2008046419A1 (fr) * 2006-10-18 2008-04-24 Pbi-Dansensor A/S Dispositif destiné à être utilisé pour tester l'imperméabilité de contenants
GB0701326D0 (en) 2007-01-24 2007-03-07 Obrist Closures Switzerland A perforable closure
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DE102008060995A1 (de) * 2008-12-09 2010-06-10 West Pharmaceutical Services Deutschland Gmbh & Co. Kg Verschluss für ein Medikamentenbehältnis
US8295015B2 (en) * 2009-02-06 2012-10-23 Tdk Corporation Magnetoresistive element, thin film magnetic head, magnetic head slider, head gimbal assembly, head arm assembly and magnetic disk device
DE202010012728U1 (de) * 2010-09-22 2011-11-29 Deutsche Gesellschaft für Humanplasma mbH Blutplasmasammelflasche
JP5594888B2 (ja) * 2010-10-27 2014-09-24 内外化成株式会社 医療用キャップ及びその製造方法
DE102011002189A1 (de) * 2011-04-20 2012-10-25 Helvoet Pharma Belgium N.V. Verschlusskappe
JP5896632B2 (ja) * 2011-07-05 2016-03-30 三笠産業株式会社 医療用キャップの製造方法
FR2986782B1 (fr) * 2012-02-13 2014-03-07 Raymond A & Cie Dispositif de verrouillage de bouchon sur recipient a collerette, recipient a collerette obture par bouchon pourvu d'un tel dispositif de verrouillage
CN103057829B (zh) * 2013-01-31 2014-11-05 浙江凌大包装有限公司 一种酒瓶的密封装置
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CN109911422B (zh) * 2019-04-02 2023-01-17 沁馨园(广州)生物科技有限公司 一种二元包装喷雾瓶
CN113905709A (zh) * 2019-05-03 2022-01-07 詹森生物科技公司 低温小瓶和小瓶组件
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Also Published As

Publication number Publication date
JP2004536686A (ja) 2004-12-09
CN1274561C (zh) 2006-09-13
US20040217082A1 (en) 2004-11-04
DE10138191A1 (de) 2003-02-27
CN1538925A (zh) 2004-10-20
DE50207315D1 (de) 2006-08-03
WO2003013972A1 (fr) 2003-02-20
DE10138191B4 (de) 2004-02-26
EP1412261A1 (fr) 2004-04-28

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