EP1095002A4 - Procede de production de vitamines - Google Patents
Procede de production de vitaminesInfo
- Publication number
- EP1095002A4 EP1095002A4 EP99932295A EP99932295A EP1095002A4 EP 1095002 A4 EP1095002 A4 EP 1095002A4 EP 99932295 A EP99932295 A EP 99932295A EP 99932295 A EP99932295 A EP 99932295A EP 1095002 A4 EP1095002 A4 EP 1095002A4
- Authority
- EP
- European Patent Office
- Prior art keywords
- geranylgeraniol
- microorganism
- farnesol
- vitamin production
- phosphate
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Withdrawn
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P7/00—Preparation of oxygen-containing organic compounds
- C12P7/02—Preparation of oxygen-containing organic compounds containing a hydroxy group
- C12P7/04—Preparation of oxygen-containing organic compounds containing a hydroxy group acyclic
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C403/00—Derivatives of cyclohexane or of a cyclohexene or of cyclohexadiene, having a side-chain containing an acyclic unsaturated part of at least four carbon atoms, this part being directly attached to the cyclohexane or cyclohexene or cyclohexadiene rings, e.g. vitamin A, beta-carotene, beta-ionone
- C07C403/06—Derivatives of cyclohexane or of a cyclohexene or of cyclohexadiene, having a side-chain containing an acyclic unsaturated part of at least four carbon atoms, this part being directly attached to the cyclohexane or cyclohexene or cyclohexadiene rings, e.g. vitamin A, beta-carotene, beta-ionone having side-chains substituted by singly-bound oxygen atoms
- C07C403/08—Derivatives of cyclohexane or of a cyclohexene or of cyclohexadiene, having a side-chain containing an acyclic unsaturated part of at least four carbon atoms, this part being directly attached to the cyclohexane or cyclohexene or cyclohexadiene rings, e.g. vitamin A, beta-carotene, beta-ionone having side-chains substituted by singly-bound oxygen atoms by hydroxy groups
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C403/00—Derivatives of cyclohexane or of a cyclohexene or of cyclohexadiene, having a side-chain containing an acyclic unsaturated part of at least four carbon atoms, this part being directly attached to the cyclohexane or cyclohexene or cyclohexadiene rings, e.g. vitamin A, beta-carotene, beta-ionone
- C07C403/24—Derivatives of cyclohexane or of a cyclohexene or of cyclohexadiene, having a side-chain containing an acyclic unsaturated part of at least four carbon atoms, this part being directly attached to the cyclohexane or cyclohexene or cyclohexadiene rings, e.g. vitamin A, beta-carotene, beta-ionone having side-chains substituted by six-membered non-aromatic rings, e.g. beta-carotene
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
- C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
- C07D311/04—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring
- C07D311/58—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring other than with oxygen or sulphur atoms in position 2 or 4
- C07D311/70—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring other than with oxygen or sulphur atoms in position 2 or 4 with two hydrocarbon radicals attached in position 2 and elements other than carbon and hydrogen in position 6
- C07D311/72—3,4-Dihydro derivatives having in position 2 at least one methyl radical and in position 6 one oxygen atom, e.g. tocopherols
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/0004—Oxidoreductases (1.)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/10—Transferases (2.)
- C12N9/1085—Transferases (2.) transferring alkyl or aryl groups other than methyl groups (2.5)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P17/00—Preparation of heterocyclic carbon compounds with only O, N, S, Se or Te as ring hetero atoms
- C12P17/02—Oxygen as only ring hetero atoms
- C12P17/06—Oxygen as only ring hetero atoms containing a six-membered hetero ring, e.g. fluorescein
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P23/00—Preparation of compounds containing a cyclohexene ring having an unsaturated side chain containing at least ten carbon atoms bound by conjugated double bonds, e.g. carotenes
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P9/00—Preparation of organic compounds containing a metal or atom other than H, N, C, O, S or halogen
-
- H—ELECTRICITY
- H01—ELECTRIC ELEMENTS
- H01Q—ANTENNAS, i.e. RADIO AERIALS
- H01Q1/00—Details of, or arrangements associated with, antennas
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C2601/00—Systems containing only non-condensed rings
- C07C2601/12—Systems containing only non-condensed rings with a six-membered ring
- C07C2601/16—Systems containing only non-condensed rings with a six-membered ring the ring being unsaturated
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Health & Medical Sciences (AREA)
- Biochemistry (AREA)
- General Engineering & Computer Science (AREA)
- Microbiology (AREA)
- Biotechnology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Molecular Biology (AREA)
- Biomedical Technology (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Pyrane Compounds (AREA)
Priority Applications (4)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
EP08003596A EP1947189B1 (fr) | 1998-07-06 | 1999-07-06 | Procede de production de vitamines |
EP10180179.3A EP2305825B1 (fr) | 1998-07-06 | 1999-07-06 | Procédé pour la production de vitamines |
EP09004155A EP2100963B1 (fr) | 1998-07-06 | 1999-07-06 | Procede de production de vitamines |
DK08003596.7T DK1947189T3 (da) | 1998-07-06 | 1999-07-06 | Fremgangsmåde til vitaminfremstilling |
Applications Claiming Priority (7)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US9196498P | 1998-07-06 | 1998-07-06 | |
US9198398P | 1998-07-06 | 1998-07-06 | |
US9195198P | 1998-07-06 | 1998-07-06 | |
US91983P | 1998-07-06 | ||
US91951P | 1998-07-06 | ||
US91964P | 1998-07-06 | ||
PCT/US1999/015264 WO2000001650A1 (fr) | 1998-07-06 | 1999-07-06 | Procede de production de vitamines |
Related Child Applications (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
EP10180179.3A Division EP2305825B1 (fr) | 1998-07-06 | 1999-07-06 | Procédé pour la production de vitamines |
EP08003596A Division EP1947189B1 (fr) | 1998-07-06 | 1999-07-06 | Procede de production de vitamines |
Publications (2)
Publication Number | Publication Date |
---|---|
EP1095002A1 EP1095002A1 (fr) | 2001-05-02 |
EP1095002A4 true EP1095002A4 (fr) | 2005-08-03 |
Family
ID=27377004
Family Applications (3)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
EP09004155A Expired - Lifetime EP2100963B1 (fr) | 1998-07-06 | 1999-07-06 | Procede de production de vitamines |
EP08003596A Expired - Lifetime EP1947189B1 (fr) | 1998-07-06 | 1999-07-06 | Procede de production de vitamines |
EP99932295A Withdrawn EP1095002A4 (fr) | 1998-07-06 | 1999-07-06 | Procede de production de vitamines |
Family Applications Before (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
EP09004155A Expired - Lifetime EP2100963B1 (fr) | 1998-07-06 | 1999-07-06 | Procede de production de vitamines |
EP08003596A Expired - Lifetime EP1947189B1 (fr) | 1998-07-06 | 1999-07-06 | Procede de production de vitamines |
Country Status (11)
Country | Link |
---|---|
EP (3) | EP2100963B1 (fr) |
JP (1) | JP4579415B2 (fr) |
CN (1) | CN1330621A (fr) |
AT (2) | ATE490332T1 (fr) |
AU (1) | AU4863099A (fr) |
CA (2) | CA2331343C (fr) |
DE (1) | DE69943009D1 (fr) |
DK (3) | DK2100963T3 (fr) |
ES (2) | ES2379212T3 (fr) |
MX (2) | MX276941B (fr) |
WO (1) | WO2000001650A1 (fr) |
Families Citing this family (64)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP2305825B1 (fr) | 1998-07-06 | 2015-01-14 | DCV Inc. doing business as Bio-Technical Resourses | Procédé pour la production de vitamines |
ATE358723T1 (de) * | 1999-04-15 | 2007-04-15 | Calgene Llc | Nukleinsäuresequenzen für proteine die an der isoprenoid-synthese beteiligt sind |
WO2001064943A1 (fr) * | 2000-03-02 | 2001-09-07 | Center For Advanced Science And Technology Incubation, Ltd. | Procede de criblage de substance a inhibition specifique de la voie non mevalonate |
US6872815B1 (en) | 2000-10-14 | 2005-03-29 | Calgene Llc | Nucleic acid sequences to proteins involved in tocopherol synthesis |
EP2281890A1 (fr) | 2000-07-31 | 2011-02-09 | Danisco US Inc. | Manipulation de gènes des voies du mévalonate et de l'isoprénoïde pour créer de nouveaux traits dans des organismes transgéniques |
US6841717B2 (en) | 2000-08-07 | 2005-01-11 | Monsanto Technology, L.L.C. | Methyl-D-erythritol phosphate pathway genes |
JP4013535B2 (ja) | 2000-12-28 | 2007-11-28 | トヨタ自動車株式会社 | 微生物によるプレニルアルコールの高生産方法 |
WO2002053747A1 (fr) * | 2000-12-28 | 2002-07-11 | Toyota Jidosha Kabushiki Kaisha | Procede de production d'alcool de prenyl |
JP3838033B2 (ja) * | 2000-12-28 | 2006-10-25 | トヨタ自動車株式会社 | プレニルアルコールの製造方法 |
JP3894119B2 (ja) | 2000-12-28 | 2007-03-14 | トヨタ自動車株式会社 | プレニルアルコールの製造方法 |
JP2003088368A (ja) * | 2001-09-18 | 2003-03-25 | Toyota Motor Corp | プレニルアルコールの製造方法 |
JP2002253284A (ja) | 2000-12-28 | 2002-09-10 | Toyota Motor Corp | 微生物によるゲラニルゲラニオール及びその類縁化合物の製造方法 |
US7161061B2 (en) | 2001-05-09 | 2007-01-09 | Monsanto Technology Llc | Metabolite transporters |
EP1392106B1 (fr) | 2001-05-09 | 2008-12-31 | Monsanto Technology LLC | Genes tyra et utilisations associees |
EP1392824B1 (fr) * | 2001-06-06 | 2008-08-20 | DSM IP Assets B.V. | Production amelioree d'isoprenoides |
AU2002329759A1 (en) | 2001-08-17 | 2003-03-03 | Monsanto Technology Llc | Methyltransferase genes and uses thereof |
WO2003034812A2 (fr) | 2001-10-25 | 2003-05-01 | Monsanto Technology Llc | Methyltransferases aromatiques et utilisations associees |
US7172886B2 (en) | 2001-12-06 | 2007-02-06 | The Regents Of The University Of California | Biosynthesis of isopentenyl pyrophosphate |
US7192751B2 (en) | 2001-12-06 | 2007-03-20 | The Regents Of The University Of California | Biosynthesis of amorpha-4,11-diene |
CA2478957C (fr) | 2002-03-19 | 2013-07-02 | Monsanto Technology, Llc | Acides nucleiques et polypeptides se rapportant a l'enzyme homogentisate prenyl transferase ("hpt"), et utilisations correspondantes |
CA2487144C (fr) * | 2002-06-21 | 2012-06-12 | Dsm Ip Assets B.V. | Augmentation de la production de carotenoides par l'inhibition de la biosynthese du squalene |
BR0313270A (pt) | 2002-08-05 | 2005-08-02 | Monsanto Technology Llc | Genes relacionados com a biosìntese de tocoferol e usos dos mesmos |
DE60320812D1 (en) | 2002-09-27 | 2008-06-19 | Dsm Ip Assets Bv | Squalene synthase (sqs) gen |
MXPA06013502A (es) | 2004-05-21 | 2007-03-01 | Univ California | Metodo para mejorar la produccion de compuestos isoprenoides. |
CA2574593C (fr) | 2004-07-27 | 2016-07-05 | The Regents Of The University Of California | Cellules hotes genetiquement modifiees et utilisation de celles-ci pour produire des composes isoprenoides |
EP2371967B1 (fr) | 2005-03-18 | 2015-06-03 | DSM IP Assets B.V. | Production de caroténoïdes dans des levures oléagineuses et des champignons |
JP4824985B2 (ja) * | 2005-10-13 | 2011-11-30 | 株式会社Adeka | ファルネシル二リン酸の製造方法 |
US8691555B2 (en) | 2006-09-28 | 2014-04-08 | Dsm Ip Assests B.V. | Production of carotenoids in oleaginous yeast and fungi |
KR101523255B1 (ko) | 2007-06-01 | 2015-05-29 | 솔라짐, 인코포레이티드 | 미생물에서 오일의 생성 |
MX302107B (es) | 2007-09-20 | 2012-08-08 | Amyris Biotechnologies Inc | Produccion de isoprenoides. |
JP5174430B2 (ja) * | 2007-11-06 | 2013-04-03 | 花王株式会社 | 2−フェニルエチルアルコールの製造方法 |
ZA201102109B (en) * | 2008-09-15 | 2013-10-30 | Goodyear Tire & Rubber | Conversion of prenyl derivatives to isoprene |
KR101888973B1 (ko) * | 2008-11-28 | 2018-08-16 | 테라비아 홀딩스 인코포레이티드 | 종속영양성 미생물에서 맞춤 오일의 생성 |
MX352746B (es) | 2010-05-28 | 2017-12-06 | Terravia Holdings Inc | Aceites específicos producidos a partir de microorganismos heterótrofos recombinantes. |
BR112012030836B8 (pt) | 2010-06-02 | 2024-02-06 | Evolva Nutrition Inc | Hospedeiro recombinante que compreende genes recombinantes para produção de esteviol ou glicosídeo de esteviol, método para produzir esteviol, glicosídeo de esteviol ou composição de glicosídeo de esteviol e método para sintetizar esteviol ou glicosídeo de esteviol |
CN108823254A (zh) | 2010-11-03 | 2018-11-16 | 柯碧恩生物技术公司 | 具有降低倾点的微生物油、从其中产生的介电流体、以及相关方法 |
AU2012212079B2 (en) | 2011-02-02 | 2016-07-28 | Corbion Biotech, Inc. | Tailored oils produced from recombinant oleaginous microorganisms |
AU2012253803A1 (en) | 2011-05-06 | 2013-12-05 | Terravia Holdings, Inc. | Genetically engineered microorganisms that metabolize xylose |
AU2012253564A1 (en) * | 2011-05-09 | 2013-10-31 | Amyris, Inc. | Production of acetyl-coenzyme A derived compounds |
WO2013022989A2 (fr) | 2011-08-08 | 2013-02-14 | Evolva Sa | Production par recombinaison de glycosides de stéviol |
US8945908B2 (en) | 2012-04-18 | 2015-02-03 | Solazyme, Inc. | Tailored oils |
MY190346A (en) | 2013-02-06 | 2022-04-15 | Evolva Sa | Methods for improved production of rebaudioside d and rebaudioside m |
BR112015019160A2 (pt) | 2013-02-11 | 2017-08-22 | Dalgaard Mikkelsen Michael | Produção de glicosídeos de esteviol em hospedeiros recombinantes |
WO2014176515A2 (fr) | 2013-04-26 | 2014-10-30 | Solazyme, Inc. | Huiles à teneur faible en acides gras polyinsaturés et leurs utilisations |
CN105829521A (zh) | 2013-10-04 | 2016-08-03 | 索拉兹米公司 | 定制油 |
WO2016007862A2 (fr) | 2014-07-10 | 2016-01-14 | Solazyme, Inc. | Nouveaux gènes de la cétoacyl-acp-synthase et leurs utilisations |
SG10201901007PA (en) | 2014-08-11 | 2019-03-28 | Evolva Sa | Production of steviol glycosides in recombinant hosts |
WO2016038095A2 (fr) | 2014-09-09 | 2016-03-17 | Evolva Sa | Production de glycosides de stéviol dans des hôtes de recombinaison |
CN108337892B (zh) | 2015-01-30 | 2022-06-24 | 埃沃尔瓦公司 | 在重组宿主中生产甜菊醇糖苷 |
EP3862426A3 (fr) | 2015-03-16 | 2021-11-17 | DSM IP Assets B.V. | Glycosyltransférases udp |
US10837041B2 (en) | 2015-08-07 | 2020-11-17 | Evolva Sa | Production of steviol glycosides in recombinant hosts |
CN105153102A (zh) * | 2015-09-30 | 2015-12-16 | 宜春大海龟生命科学有限公司 | 以混合生育酚为原料制备α-生育酚的方法 |
CN109195457A (zh) | 2016-04-13 | 2019-01-11 | 埃沃尔瓦公司 | 在重组宿主中产生甜菊醇糖苷 |
US10815514B2 (en) | 2016-05-16 | 2020-10-27 | Evolva Sa | Production of steviol glycosides in recombinant hosts |
CN110100006A (zh) | 2016-11-07 | 2019-08-06 | 埃沃尔瓦公司 | 重组宿主中甜菊糖苷的生产 |
EP3720944A1 (fr) | 2017-12-07 | 2020-10-14 | Zymergen Inc. | Voies de biosynthèse manipulées pour la production de (6e)-8-hydroxygéraniol par fermentation |
CN111868047A (zh) | 2017-12-21 | 2020-10-30 | 齐默尔根公司 | 荆芥内半缩醛氧化还原酶、荆芥内半缩醛合酶和能够产生荆芥内酯的微生物 |
CN109609579B (zh) * | 2018-12-31 | 2022-04-05 | 陕西师范大学 | 一种产β-胡萝卜素的基因工程菌及其构建方法 |
CN109884216A (zh) * | 2019-04-10 | 2019-06-14 | 西南医科大学 | 一种高效液相色谱测定载药胶束中法尼醛含量的方法 |
CN110903190B (zh) * | 2019-12-09 | 2022-07-12 | 万华化学集团股份有限公司 | 一种维生素a及维生素a酯的制备方法 |
CN110950791B (zh) * | 2019-12-09 | 2021-12-14 | 万华化学集团股份有限公司 | 一种维生素a及维生素a酯制备方法 |
JP2023506144A (ja) * | 2019-12-23 | 2023-02-15 | ディーエスエム アイピー アセッツ ビー.ブイ. | 脱水素化方法 |
CN113621631A (zh) * | 2021-08-11 | 2021-11-09 | 昆明理工大学 | 一种甲羟戊酸激酶基因rkmk及其应用 |
CN113969288A (zh) * | 2021-10-29 | 2022-01-25 | 湖北冠众通科技有限公司 | 一种高产法尼醇基因工程菌及其构建方法与应用 |
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JP3151371B2 (ja) * | 1995-03-10 | 2001-04-03 | 麒麟麦酒株式会社 | カロチノイド生産量の増量に有用なdna鎖 |
CA2192253A1 (fr) | 1995-12-07 | 1997-06-08 | Susan Ferro-Novick | Proteines de geranylgeranyl-diphosphate-synthase, molecules d'acide nucleique; leurs utilisations |
ES2229288T3 (es) * | 1995-12-22 | 2005-04-16 | Dsm Ip Assets B.V. | Metodos mejorados para transformar cepas de phaffia, cepas de phaffia transformadas asi obtenidas y dna recombinante en dichos metodos. |
US5744341A (en) * | 1996-03-29 | 1998-04-28 | University Of Maryland College Park | Genes of carotenoid biosynthesis and metabolism and a system for screening for such genes |
EP0955363A3 (fr) * | 1998-05-06 | 2004-01-28 | F. Hoffmann-La Roche Ag | Séquences d'ADN codant pour des enzymes impliqués dans la production des isoprénoides |
-
1999
- 1999-07-06 WO PCT/US1999/015264 patent/WO2000001650A1/fr active Application Filing
- 1999-07-06 MX MXPA04002408 patent/MX276941B/es unknown
- 1999-07-06 CA CA2331343A patent/CA2331343C/fr not_active Expired - Lifetime
- 1999-07-06 JP JP2000558056A patent/JP4579415B2/ja not_active Expired - Lifetime
- 1999-07-06 DE DE69943009T patent/DE69943009D1/de not_active Expired - Lifetime
- 1999-07-06 DK DK09004155.9T patent/DK2100963T3/da active
- 1999-07-06 EP EP09004155A patent/EP2100963B1/fr not_active Expired - Lifetime
- 1999-07-06 AU AU48630/99A patent/AU4863099A/en not_active Abandoned
- 1999-07-06 DK DK08003596.7T patent/DK1947189T3/da active
- 1999-07-06 CN CN99810559A patent/CN1330621A/zh active Pending
- 1999-07-06 EP EP08003596A patent/EP1947189B1/fr not_active Expired - Lifetime
- 1999-07-06 MX MXPA01000216 patent/MX219130B/es unknown
- 1999-07-06 EP EP99932295A patent/EP1095002A4/fr not_active Withdrawn
- 1999-07-06 CA CA2831321A patent/CA2831321C/fr not_active Expired - Lifetime
- 1999-07-06 AT AT08003596T patent/ATE490332T1/de not_active IP Right Cessation
- 1999-07-06 ES ES09004155T patent/ES2379212T3/es not_active Expired - Lifetime
- 1999-07-06 AT AT09004155T patent/ATE537265T1/de active
- 1999-07-06 ES ES10180179.3T patent/ES2534937T3/es not_active Expired - Lifetime
- 1999-07-06 DK DK10180179T patent/DK2305825T3/en active
Patent Citations (2)
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DE2404621A1 (de) * | 1974-01-29 | 1975-08-07 | Teijin Ltd | Verfahren zur herstellung von verbindungen, die einen chromanring enthalten |
GB1479272A (en) * | 1974-12-23 | 1977-07-13 | Kuraray Co | Process for preparing a stereospecific farnesol |
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Title |
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CHAMBON C ET AL: "ISOLATION AND PROPERTIES OF YEAST MUTANTS AFFECTED IN FARNESYL DIPHOSPHATE SYNTHETASE", CURRENT GENETICS, NEW YORK, NY, US, vol. 18, 1990, pages 41 - 46, XP002909498, ISSN: 0172-8083 * |
Also Published As
Publication number | Publication date |
---|---|
CA2831321C (fr) | 2018-05-15 |
DK1947189T3 (da) | 2011-03-14 |
ATE490332T1 (de) | 2010-12-15 |
WO2000001650A1 (fr) | 2000-01-13 |
ES2379212T3 (es) | 2012-04-23 |
EP1095002A1 (fr) | 2001-05-02 |
MX276941B (es) | 2010-06-28 |
EP2100963B1 (fr) | 2011-12-14 |
CN1330621A (zh) | 2002-01-09 |
EP1947189A3 (fr) | 2008-10-08 |
ES2534937T3 (es) | 2015-04-30 |
JP2002519049A (ja) | 2002-07-02 |
MX219130B (es) | 2004-02-10 |
JP4579415B2 (ja) | 2010-11-10 |
ATE537265T1 (de) | 2011-12-15 |
DK2305825T3 (en) | 2015-03-02 |
EP2100963A1 (fr) | 2009-09-16 |
CA2831321A1 (fr) | 2000-01-13 |
AU4863099A (en) | 2000-01-24 |
EP1947189B1 (fr) | 2010-12-01 |
CA2331343A1 (fr) | 2000-01-13 |
EP1947189A2 (fr) | 2008-07-23 |
DE69943009D1 (de) | 2011-01-13 |
MXPA01000216A (es) | 2002-10-17 |
CA2331343C (fr) | 2014-01-14 |
DK2100963T3 (da) | 2012-04-02 |
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