EP0350772A1 - Ampoule en matière synthétique - Google Patents
Ampoule en matière synthétique Download PDFInfo
- Publication number
- EP0350772A1 EP0350772A1 EP89112236A EP89112236A EP0350772A1 EP 0350772 A1 EP0350772 A1 EP 0350772A1 EP 89112236 A EP89112236 A EP 89112236A EP 89112236 A EP89112236 A EP 89112236A EP 0350772 A1 EP0350772 A1 EP 0350772A1
- Authority
- EP
- European Patent Office
- Prior art keywords
- ampoule
- constriction
- head
- diameter
- adjoining
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Ceased
Links
Images
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61J—CONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
- A61J1/00—Containers specially adapted for medical or pharmaceutical purposes
- A61J1/05—Containers specially adapted for medical or pharmaceutical purposes for collecting, storing or administering blood, plasma or medical fluids ; Infusion or perfusion containers
- A61J1/06—Ampoules or carpules
- A61J1/067—Flexible ampoules, the contents of which are expelled by squeezing
Definitions
- the invention relates to an ampoule made of plastic with a molded ampoule head which can be separated from the ampoule body without tools and which is produced in the blowing process and filled in the blowing device and sealed by welding its head. is preferably greater than 5 mm.
- the invention is therefore based on the object of creating an ampoule of the type mentioned at the outset, which makes it possible to realize larger opening diameters than hitherto. This object is achieved by an ampoule with the features of claim 1.
- the former no longer needs to be rotated around the longitudinal axis of the ampoule body. Rather, it is sufficient to tilt the ampoule head to the side.
- the wall is basically torn off due to the constriction.
- the force required for tilting the ampoule head can also be applied well with a relatively large opening diameter, especially since one is not limited to grasping the ampoule head with two fingers. You can also load it with the palm of your hand, for example.
- a clean edge is obtained. This may be due to the fact that the zone of reduced wall thickness is very narrow.
- sections according to claim 4 adjoin the constriction on both sides.
- the ampoule head preferably has the features of claims 5 and 8 to 10.
- An ampoule 1 made of plastic aseptically manufactured in the blowing process and yet filled in the blowing device and sealed by welding in the area of its head has a cylindrical ampoule body 2 which is closed at one end by a base 3.
- the ampoule body could also have a different cross-sectional shape, for example an elliptical shape. Its other end is formed by an also cylindrical, but reduced in diameter end portion 2 ', the wall thickness of which is equal to that of the rest of the ampoule body 2. Its outer diameter is only 50% of the outer diameter of the remaining part of the ampoule body 2.
- the transition to the end section 2 ' is, as shown in FIGS. 1 and 2, conical.
- the ampoule head 5 connects at the end section 2 'of the ampoule body 2 at the end section 2 'of the ampoule body 2 at the end section 2 'of the ampoule body 2 is followed by a constriction 4, to which in turn the ampoule head 5 connects.
- the latter has the same outer diameter as the end section 2 'and is closed at the end facing away from the ampoule body 2 by a spherical shell-shaped material section.
- the ampoule head 5 deviates from the cylindrical shape only to the extent that two troughs 6 of the same mirror-inverted design are provided at an axial distance from the constriction 4 for the engagement of the fingers that grip the ampoule head 5.
- the troughs 6 have the shape of channels running transversely to the longitudinal direction of the ampoule 1.
- the axial length of the ampoule head 5 is about two to three times as large as its outer diameter.
- the constriction 4 as shown in FIGS. 1 and 2, has the shape of an annular groove with a wedge-shaped cross-sectional profile, as a result of which the base of the constriction 4 has an extremely small axial extent. Only in the area of this reason is the thickness of the wall reduced to a small value, namely to about 0.2-0.4 mm.
- the two flanks of the constriction 4 enclose an angle of 45 °.
- the angle between the flank on the side of the ampoule head 5 and a radial plane is 15 °, which results in a value of 30 ° for the angle between the other flank and the radial plane.
- the inner diameter at the base of the constriction 4 is approximately 8 mm in the exemplary embodiment, which is why the torque that would be required to separate the ampoule head 5 from the ampoule body 2 by turning can no longer be applied by hand. Values larger than 0.8 mm can also be selected.
- the ampoule head 5 is tilted to the side.
- the ampoule head 5 can be grasped with the fingers. But it is also sufficient to push it aside, for example with the ball of your hand.
- the axial length of the ampoule head 5 is completely sufficient to be able to apply the required force.
- the tilting of the ampoule head 5, which is favored by the wedge shape of the cross-sectional profile of the constriction 4, has the consequence that plastic is torn off in the region of the bottom of the constriction 4, which defines the desired separation point becomes. This tearing off is possible since the zone of reduced wall thickness has a very small axial extent without fringe-like material parts being formed along the edge of the opening which is present after the ampoule head 5 has been separated.
- the ampoule 1 can be produced and the contents introduced by one of the known methods.
Landscapes
- Health & Medical Sciences (AREA)
- Hematology (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Medical Preparation Storing Or Oral Administration Devices (AREA)
- Containers Having Bodies Formed In One Piece (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DE19883823428 DE3823428A1 (de) | 1988-07-11 | 1988-07-11 | Ampulle aus kunststoff |
DE3823428 | 1988-07-11 |
Publications (1)
Publication Number | Publication Date |
---|---|
EP0350772A1 true EP0350772A1 (fr) | 1990-01-17 |
Family
ID=6358409
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
EP89112236A Ceased EP0350772A1 (fr) | 1988-07-11 | 1989-07-05 | Ampoule en matière synthétique |
Country Status (3)
Country | Link |
---|---|
EP (1) | EP0350772A1 (fr) |
JP (1) | JP2825533B2 (fr) |
DE (1) | DE3823428A1 (fr) |
Cited By (9)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5046627A (en) * | 1989-05-24 | 1991-09-10 | Bernd Hansen | Ampule |
DE4408394A1 (de) * | 1994-03-12 | 1995-09-21 | Bernd Hansen | Verpackungsmittel für Medizinprodukte, wie Kontaktlinsen, insbesondere Einwegkontaktlinsen |
EP0706406A1 (fr) * | 1993-07-02 | 1996-04-17 | Barry Farris | Procede et dispositif de remplissage de seringues sans aiguille |
WO1998025829A1 (fr) * | 1996-12-09 | 1998-06-18 | Bausch & Lomb Incorporated | Contenant flexible jetable apres emploi |
WO2000020055A1 (fr) | 1998-10-01 | 2000-04-13 | Barry Farris | Systeme de transfert, sans aiguille, d'un liquide d'un contenant a une seringue sans contamination par l'air ambient |
US6296150B1 (en) | 1999-02-25 | 2001-10-02 | Barry Farris | Medicinal dosing apparatus and method |
US6918418B1 (en) | 2000-03-13 | 2005-07-19 | Barry Farris | Method and apparatus for the storage and transfer of a lyophilisate |
EP3219305A1 (fr) | 2016-03-16 | 2017-09-20 | Apostolos Georgopoulos | Formule de fosfomycine destinee a l'administration parenterale |
EP4268805A1 (fr) | 2022-04-29 | 2023-11-01 | Apostolos Georgopoulos | Formulation de fosfomycine destinée à l'administration par voie parentérale et procédé de production |
Families Citing this family (9)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DK0730858T3 (da) | 1995-03-09 | 1999-09-27 | Hansen Bernd | Flaske af plast og fremgangsmåde til dens fremstilling |
DE19522451C2 (de) * | 1995-06-21 | 1997-11-06 | Bernd Hansen | Vorrichtung zur Abgabe eines fließfähigen Stoffes aus einem Behälter |
DE19801320B4 (de) * | 1998-01-16 | 2004-08-26 | Schott Glas | Befüllter und verschlossener Kunststoffbehälter und Verfahren zu seiner Herstellung |
DE102005038619A1 (de) | 2005-08-16 | 2007-02-22 | Pari GmbH Spezialisten für effektive Inhalation | Inhalationstherapievorrichtung mit einer Ampulle für die Bevorratung eines zu vernebelnden Medikaments |
JP4726593B2 (ja) * | 2005-09-28 | 2011-07-20 | 株式会社吉野工業所 | 自立袋 |
DE102007056462B4 (de) | 2007-11-23 | 2011-10-27 | Pari Pharma Gmbh | Einwegampulle für eine Vorrichtung zur Erzeugung von Aerosolen |
JP5452882B2 (ja) * | 2008-04-30 | 2014-03-26 | 株式会社吉野工業所 | 樹脂製アンプル |
KR100932773B1 (ko) * | 2009-08-17 | 2009-12-21 | 피앤비팩(주) | 플라스틱 앰플 어셈블리 |
JP5897375B2 (ja) * | 2012-03-30 | 2016-03-30 | 株式会社吉野工業所 | 合成樹脂製アンプル容器 |
Citations (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CH528413A (de) * | 1970-08-18 | 1972-09-30 | Hartmann Emil | Kunststoffbehälter mit Abdrehverschluss |
DE2140650A1 (de) * | 1971-08-13 | 1973-02-22 | Pmd Entwicklungswerk | Kunststoffbehaelter |
US3749271A (en) * | 1971-06-22 | 1973-07-31 | Becton Dickinson Co | Resealable ampoule closure |
FR2257500A1 (fr) * | 1974-01-10 | 1975-08-08 | Akerlund & Rausing Ab | |
DE3244403A1 (de) * | 1982-12-01 | 1984-06-07 | Hansen, Gerhard, 7166 Sulzbach-Laufen | Behaelter aus einem elastischen kunststoff |
DE8808881U1 (de) * | 1988-07-11 | 1988-08-25 | Hansen, Bernd, Dipl.-Ing., 7166 Sulzbach-Laufen | Ampulle aus Kunststoff |
Family Cites Families (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE1921395U (de) * | 1965-04-17 | 1965-08-12 | Schwarzkopf Fa Hans | Abdrehverschluss fuer plastikflaschen. |
JPS5211904B2 (fr) * | 1973-09-28 | 1977-04-02 | ||
GB1444848A (en) * | 1974-08-29 | 1976-08-04 | Barnes Hind Diagnostics Inc | Plastics containers |
-
1988
- 1988-07-11 DE DE19883823428 patent/DE3823428A1/de active Granted
-
1989
- 1989-07-05 EP EP89112236A patent/EP0350772A1/fr not_active Ceased
- 1989-07-11 JP JP18011089A patent/JP2825533B2/ja not_active Expired - Lifetime
Patent Citations (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CH528413A (de) * | 1970-08-18 | 1972-09-30 | Hartmann Emil | Kunststoffbehälter mit Abdrehverschluss |
US3749271A (en) * | 1971-06-22 | 1973-07-31 | Becton Dickinson Co | Resealable ampoule closure |
DE2140650A1 (de) * | 1971-08-13 | 1973-02-22 | Pmd Entwicklungswerk | Kunststoffbehaelter |
FR2257500A1 (fr) * | 1974-01-10 | 1975-08-08 | Akerlund & Rausing Ab | |
DE3244403A1 (de) * | 1982-12-01 | 1984-06-07 | Hansen, Gerhard, 7166 Sulzbach-Laufen | Behaelter aus einem elastischen kunststoff |
DE8808881U1 (de) * | 1988-07-11 | 1988-08-25 | Hansen, Bernd, Dipl.-Ing., 7166 Sulzbach-Laufen | Ampulle aus Kunststoff |
Cited By (21)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5046627A (en) * | 1989-05-24 | 1991-09-10 | Bernd Hansen | Ampule |
US6673050B1 (en) | 1993-07-02 | 2004-01-06 | Barry Farris | Method and apparatus for loading syringes without the need for hypodermic needles |
US6045538A (en) * | 1993-07-02 | 2000-04-04 | Farris; Barry | Method and apparatus for loading syringes without the need for hypodermic needles |
EP0706406A1 (fr) * | 1993-07-02 | 1996-04-17 | Barry Farris | Procede et dispositif de remplissage de seringues sans aiguille |
EP0706406A4 (fr) * | 1993-07-02 | 1997-01-08 | Barry Farris | Procede et dispositif de remplissage de seringues sans aiguille |
AU692819B2 (en) * | 1994-03-12 | 1998-06-18 | Bernd Hansen | Package for medicinal products |
DE4408394A1 (de) * | 1994-03-12 | 1995-09-21 | Bernd Hansen | Verpackungsmittel für Medizinprodukte, wie Kontaktlinsen, insbesondere Einwegkontaktlinsen |
DE4408394C2 (de) * | 1994-03-12 | 1999-06-24 | Bernd Hansen | Verpackungsmittel für Kontaktlinsen, insbesondere Einwegkontaktlinsen |
EP0676333A1 (fr) * | 1994-03-12 | 1995-10-11 | Hansen, Bernd, Dipl.-Ing. | Moyens d'emballage pour produits médicaux, tels que des lentilles de contact, en particulier des lentilles souples de contact |
WO1998025829A1 (fr) * | 1996-12-09 | 1998-06-18 | Bausch & Lomb Incorporated | Contenant flexible jetable apres emploi |
US6241124B1 (en) | 1996-12-09 | 2001-06-05 | Bausch & Lomb Incorporated | Single-use container |
WO2000020055A1 (fr) | 1998-10-01 | 2000-04-13 | Barry Farris | Systeme de transfert, sans aiguille, d'un liquide d'un contenant a une seringue sans contamination par l'air ambient |
US6308747B1 (en) | 1998-10-01 | 2001-10-30 | Barry Farris | Needleless method and apparatus for transferring liquid from a container to an injecting device without ambient air contamination |
US6585134B2 (en) | 1998-10-01 | 2003-07-01 | Barry Farris | Needleless method and apparatus for transferring liquid from a container to an injecting device without ambient air contamination |
US6547099B1 (en) | 1999-02-25 | 2003-04-15 | Barry Farris | Medicinal dosing apparatus and method |
US6296150B1 (en) | 1999-02-25 | 2001-10-02 | Barry Farris | Medicinal dosing apparatus and method |
US6918418B1 (en) | 2000-03-13 | 2005-07-19 | Barry Farris | Method and apparatus for the storage and transfer of a lyophilisate |
EP3219305A1 (fr) | 2016-03-16 | 2017-09-20 | Apostolos Georgopoulos | Formule de fosfomycine destinee a l'administration parenterale |
WO2017158099A1 (fr) | 2016-03-16 | 2017-09-21 | Apostolos Georgopoulos | Formulations de fosfomycine pour une administration parentérale |
EP3603618A1 (fr) | 2016-03-16 | 2020-02-05 | Apostolos Georgopoulos | Formule de fosfomycine destinée à l'administration parenterale |
EP4268805A1 (fr) | 2022-04-29 | 2023-11-01 | Apostolos Georgopoulos | Formulation de fosfomycine destinée à l'administration par voie parentérale et procédé de production |
Also Published As
Publication number | Publication date |
---|---|
DE3823428A1 (de) | 1990-01-18 |
JPH0265863A (ja) | 1990-03-06 |
JP2825533B2 (ja) | 1998-11-18 |
DE3823428C2 (fr) | 1990-11-22 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
PUAI | Public reference made under article 153(3) epc to a published international application that has entered the european phase |
Free format text: ORIGINAL CODE: 0009012 |
|
17P | Request for examination filed |
Effective date: 19890705 |
|
AK | Designated contracting states |
Kind code of ref document: A1 Designated state(s): DE FR GB IT |
|
17Q | First examination report despatched |
Effective date: 19900821 |
|
STAA | Information on the status of an ep patent application or granted ep patent |
Free format text: STATUS: THE APPLICATION HAS BEEN REFUSED |
|
18R | Application refused |
Effective date: 19920602 |
|
APAF | Appeal reference modified |
Free format text: ORIGINAL CODE: EPIDOSCREFNE |