EP0350772A1 - Ampulle aus Kunststoff - Google Patents

Ampulle aus Kunststoff Download PDF

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Publication number
EP0350772A1
EP0350772A1 EP89112236A EP89112236A EP0350772A1 EP 0350772 A1 EP0350772 A1 EP 0350772A1 EP 89112236 A EP89112236 A EP 89112236A EP 89112236 A EP89112236 A EP 89112236A EP 0350772 A1 EP0350772 A1 EP 0350772A1
Authority
EP
European Patent Office
Prior art keywords
ampoule
constriction
head
diameter
adjoining
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
EP89112236A
Other languages
German (de)
English (en)
French (fr)
Inventor
Bernd Dipl.-Ing. Hansen
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Individual
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Publication of EP0350772A1 publication Critical patent/EP0350772A1/de
Ceased legal-status Critical Current

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Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61JCONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
    • A61J1/00Containers specially adapted for medical or pharmaceutical purposes
    • A61J1/05Containers specially adapted for medical or pharmaceutical purposes for collecting, storing or administering blood, plasma or medical fluids ; Infusion or perfusion containers
    • A61J1/06Ampoules or carpules
    • A61J1/067Flexible ampoules, the contents of which are expelled by squeezing

Definitions

  • the invention relates to an ampoule made of plastic with a molded ampoule head which can be separated from the ampoule body without tools and which is produced in the blowing process and filled in the blowing device and sealed by welding its head. is preferably greater than 5 mm.
  • the invention is therefore based on the object of creating an ampoule of the type mentioned at the outset, which makes it possible to realize larger opening diameters than hitherto. This object is achieved by an ampoule with the features of claim 1.
  • the former no longer needs to be rotated around the longitudinal axis of the ampoule body. Rather, it is sufficient to tilt the ampoule head to the side.
  • the wall is basically torn off due to the constriction.
  • the force required for tilting the ampoule head can also be applied well with a relatively large opening diameter, especially since one is not limited to grasping the ampoule head with two fingers. You can also load it with the palm of your hand, for example.
  • a clean edge is obtained. This may be due to the fact that the zone of reduced wall thickness is very narrow.
  • sections according to claim 4 adjoin the constriction on both sides.
  • the ampoule head preferably has the features of claims 5 and 8 to 10.
  • An ampoule 1 made of plastic aseptically manufactured in the blowing process and yet filled in the blowing device and sealed by welding in the area of its head has a cylindrical ampoule body 2 which is closed at one end by a base 3.
  • the ampoule body could also have a different cross-sectional shape, for example an elliptical shape. Its other end is formed by an also cylindrical, but reduced in diameter end portion 2 ', the wall thickness of which is equal to that of the rest of the ampoule body 2. Its outer diameter is only 50% of the outer diameter of the remaining part of the ampoule body 2.
  • the transition to the end section 2 ' is, as shown in FIGS. 1 and 2, conical.
  • the ampoule head 5 connects at the end section 2 'of the ampoule body 2 at the end section 2 'of the ampoule body 2 at the end section 2 'of the ampoule body 2 is followed by a constriction 4, to which in turn the ampoule head 5 connects.
  • the latter has the same outer diameter as the end section 2 'and is closed at the end facing away from the ampoule body 2 by a spherical shell-shaped material section.
  • the ampoule head 5 deviates from the cylindrical shape only to the extent that two troughs 6 of the same mirror-inverted design are provided at an axial distance from the constriction 4 for the engagement of the fingers that grip the ampoule head 5.
  • the troughs 6 have the shape of channels running transversely to the longitudinal direction of the ampoule 1.
  • the axial length of the ampoule head 5 is about two to three times as large as its outer diameter.
  • the constriction 4 as shown in FIGS. 1 and 2, has the shape of an annular groove with a wedge-shaped cross-sectional profile, as a result of which the base of the constriction 4 has an extremely small axial extent. Only in the area of this reason is the thickness of the wall reduced to a small value, namely to about 0.2-0.4 mm.
  • the two flanks of the constriction 4 enclose an angle of 45 °.
  • the angle between the flank on the side of the ampoule head 5 and a radial plane is 15 °, which results in a value of 30 ° for the angle between the other flank and the radial plane.
  • the inner diameter at the base of the constriction 4 is approximately 8 mm in the exemplary embodiment, which is why the torque that would be required to separate the ampoule head 5 from the ampoule body 2 by turning can no longer be applied by hand. Values larger than 0.8 mm can also be selected.
  • the ampoule head 5 is tilted to the side.
  • the ampoule head 5 can be grasped with the fingers. But it is also sufficient to push it aside, for example with the ball of your hand.
  • the axial length of the ampoule head 5 is completely sufficient to be able to apply the required force.
  • the tilting of the ampoule head 5, which is favored by the wedge shape of the cross-sectional profile of the constriction 4, has the consequence that plastic is torn off in the region of the bottom of the constriction 4, which defines the desired separation point becomes. This tearing off is possible since the zone of reduced wall thickness has a very small axial extent without fringe-like material parts being formed along the edge of the opening which is present after the ampoule head 5 has been separated.
  • the ampoule 1 can be produced and the contents introduced by one of the known methods.

Landscapes

  • Health & Medical Sciences (AREA)
  • Hematology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medical Preparation Storing Or Oral Administration Devices (AREA)
  • Containers Having Bodies Formed In One Piece (AREA)
EP89112236A 1988-07-11 1989-07-05 Ampulle aus Kunststoff Ceased EP0350772A1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE3823428 1988-07-11
DE19883823428 DE3823428A1 (de) 1988-07-11 1988-07-11 Ampulle aus kunststoff

Publications (1)

Publication Number Publication Date
EP0350772A1 true EP0350772A1 (de) 1990-01-17

Family

ID=6358409

Family Applications (1)

Application Number Title Priority Date Filing Date
EP89112236A Ceased EP0350772A1 (de) 1988-07-11 1989-07-05 Ampulle aus Kunststoff

Country Status (3)

Country Link
EP (1) EP0350772A1 (enrdf_load_html_response)
JP (1) JP2825533B2 (enrdf_load_html_response)
DE (1) DE3823428A1 (enrdf_load_html_response)

Cited By (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5046627A (en) * 1989-05-24 1991-09-10 Bernd Hansen Ampule
DE4408394A1 (de) * 1994-03-12 1995-09-21 Bernd Hansen Verpackungsmittel für Medizinprodukte, wie Kontaktlinsen, insbesondere Einwegkontaktlinsen
EP0706406A4 (en) * 1993-07-02 1997-01-08 Barry Farris METHOD AND DEVICE FOR FILLING NEEDLESS SPLASH
WO1998025829A1 (en) * 1996-12-09 1998-06-18 Bausch & Lomb Incorporated Single-use flexible container
WO2000020055A1 (en) 1998-10-01 2000-04-13 Barry Farris Needleless system for transferring liquid from a container to a syringe without ambient air contamination
US6296150B1 (en) 1999-02-25 2001-10-02 Barry Farris Medicinal dosing apparatus and method
US6918418B1 (en) 2000-03-13 2005-07-19 Barry Farris Method and apparatus for the storage and transfer of a lyophilisate
EP3219305A1 (de) 2016-03-16 2017-09-20 Apostolos Georgopoulos Fosfomycin-formulierung zur parenteralen verabreichung
EP4268805A1 (de) 2022-04-29 2023-11-01 Apostolos Georgopoulos Fosfomycin-formulierung zur parenteralen verabreichung und herstellungsverfahren

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DK0730858T3 (da) 1995-03-09 1999-09-27 Hansen Bernd Flaske af plast og fremgangsmåde til dens fremstilling
DE19522451C2 (de) * 1995-06-21 1997-11-06 Bernd Hansen Vorrichtung zur Abgabe eines fließfähigen Stoffes aus einem Behälter
DE19801320B4 (de) * 1998-01-16 2004-08-26 Schott Glas Befüllter und verschlossener Kunststoffbehälter und Verfahren zu seiner Herstellung
RU2139821C1 (ru) * 1999-02-12 1999-10-20 Общество с ограниченной ответственностью "Технополис" Ампула
DE102005038619A1 (de) 2005-08-16 2007-02-22 Pari GmbH Spezialisten für effektive Inhalation Inhalationstherapievorrichtung mit einer Ampulle für die Bevorratung eines zu vernebelnden Medikaments
JP4726593B2 (ja) * 2005-09-28 2011-07-20 株式会社吉野工業所 自立袋
DE102007056462B4 (de) 2007-11-23 2011-10-27 Pari Pharma Gmbh Einwegampulle für eine Vorrichtung zur Erzeugung von Aerosolen
JP5452882B2 (ja) * 2008-04-30 2014-03-26 株式会社吉野工業所 樹脂製アンプル
KR100932773B1 (ko) * 2009-08-17 2009-12-21 피앤비팩(주) 플라스틱 앰플 어셈블리
JP5897375B2 (ja) * 2012-03-30 2016-03-30 株式会社吉野工業所 合成樹脂製アンプル容器

Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CH528413A (de) * 1970-08-18 1972-09-30 Hartmann Emil Kunststoffbehälter mit Abdrehverschluss
DE2140650A1 (de) * 1971-08-13 1973-02-22 Pmd Entwicklungswerk Kunststoffbehaelter
US3749271A (en) * 1971-06-22 1973-07-31 Becton Dickinson Co Resealable ampoule closure
FR2257500A1 (enrdf_load_html_response) * 1974-01-10 1975-08-08 Akerlund & Rausing Ab
DE3244403A1 (de) * 1982-12-01 1984-06-07 Hansen, Gerhard, 7166 Sulzbach-Laufen Behaelter aus einem elastischen kunststoff
DE8808881U1 (de) * 1988-07-11 1988-08-25 Hansen, Bernd, Dipl.-Ing., 7166 Sulzbach-Laufen Ampulle aus Kunststoff

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE1921395U (de) * 1965-04-17 1965-08-12 Schwarzkopf Fa Hans Abdrehverschluss fuer plastikflaschen.
JPS5211904B2 (enrdf_load_html_response) * 1973-09-28 1977-04-02
GB1444848A (en) * 1974-08-29 1976-08-04 Barnes Hind Diagnostics Inc Plastics containers

Patent Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CH528413A (de) * 1970-08-18 1972-09-30 Hartmann Emil Kunststoffbehälter mit Abdrehverschluss
US3749271A (en) * 1971-06-22 1973-07-31 Becton Dickinson Co Resealable ampoule closure
DE2140650A1 (de) * 1971-08-13 1973-02-22 Pmd Entwicklungswerk Kunststoffbehaelter
FR2257500A1 (enrdf_load_html_response) * 1974-01-10 1975-08-08 Akerlund & Rausing Ab
DE3244403A1 (de) * 1982-12-01 1984-06-07 Hansen, Gerhard, 7166 Sulzbach-Laufen Behaelter aus einem elastischen kunststoff
DE8808881U1 (de) * 1988-07-11 1988-08-25 Hansen, Bernd, Dipl.-Ing., 7166 Sulzbach-Laufen Ampulle aus Kunststoff

Cited By (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5046627A (en) * 1989-05-24 1991-09-10 Bernd Hansen Ampule
US6045538A (en) * 1993-07-02 2000-04-04 Farris; Barry Method and apparatus for loading syringes without the need for hypodermic needles
US6673050B1 (en) 1993-07-02 2004-01-06 Barry Farris Method and apparatus for loading syringes without the need for hypodermic needles
EP0706406A4 (en) * 1993-07-02 1997-01-08 Barry Farris METHOD AND DEVICE FOR FILLING NEEDLESS SPLASH
DE4408394C2 (de) * 1994-03-12 1999-06-24 Bernd Hansen Verpackungsmittel für Kontaktlinsen, insbesondere Einwegkontaktlinsen
AU692819B2 (en) * 1994-03-12 1998-06-18 Bernd Hansen Package for medicinal products
EP0676333A1 (de) * 1994-03-12 1995-10-11 Hansen, Bernd, Dipl.-Ing. Verpackungsmittel für Medizinprodukte, wie Kontaktlinsen, insbesondere Einwegkontaktlinsen
DE4408394A1 (de) * 1994-03-12 1995-09-21 Bernd Hansen Verpackungsmittel für Medizinprodukte, wie Kontaktlinsen, insbesondere Einwegkontaktlinsen
WO1998025829A1 (en) * 1996-12-09 1998-06-18 Bausch & Lomb Incorporated Single-use flexible container
US6241124B1 (en) 1996-12-09 2001-06-05 Bausch & Lomb Incorporated Single-use container
US6585134B2 (en) 1998-10-01 2003-07-01 Barry Farris Needleless method and apparatus for transferring liquid from a container to an injecting device without ambient air contamination
WO2000020055A1 (en) 1998-10-01 2000-04-13 Barry Farris Needleless system for transferring liquid from a container to a syringe without ambient air contamination
US6308747B1 (en) 1998-10-01 2001-10-30 Barry Farris Needleless method and apparatus for transferring liquid from a container to an injecting device without ambient air contamination
US6296150B1 (en) 1999-02-25 2001-10-02 Barry Farris Medicinal dosing apparatus and method
US6547099B1 (en) 1999-02-25 2003-04-15 Barry Farris Medicinal dosing apparatus and method
US6918418B1 (en) 2000-03-13 2005-07-19 Barry Farris Method and apparatus for the storage and transfer of a lyophilisate
EP3219305A1 (de) 2016-03-16 2017-09-20 Apostolos Georgopoulos Fosfomycin-formulierung zur parenteralen verabreichung
WO2017158099A1 (de) 2016-03-16 2017-09-21 Apostolos Georgopoulos Fosfomycin-formulierung zur parenteralen verabreichung
EP3603618A1 (de) 2016-03-16 2020-02-05 Apostolos Georgopoulos Fosfomycin-formulierung zur parenteralen verabreichung
EP4268805A1 (de) 2022-04-29 2023-11-01 Apostolos Georgopoulos Fosfomycin-formulierung zur parenteralen verabreichung und herstellungsverfahren

Also Published As

Publication number Publication date
JPH0265863A (ja) 1990-03-06
DE3823428C2 (enrdf_load_html_response) 1990-11-22
JP2825533B2 (ja) 1998-11-18
DE3823428A1 (de) 1990-01-18

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