EP0146063B1 - Blisterpackungen fuer teilbare Tabletten - Google Patents

Blisterpackungen fuer teilbare Tabletten Download PDF

Info

Publication number
EP0146063B1
EP0146063B1 EP84114625A EP84114625A EP0146063B1 EP 0146063 B1 EP0146063 B1 EP 0146063B1 EP 84114625 A EP84114625 A EP 84114625A EP 84114625 A EP84114625 A EP 84114625A EP 0146063 B1 EP0146063 B1 EP 0146063B1
Authority
EP
European Patent Office
Prior art keywords
package
cover
tablets
depression
film
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
EP84114625A
Other languages
German (de)
English (en)
French (fr)
Other versions
EP0146063A3 (en
EP0146063A2 (de
Inventor
Dieter Perthes
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Hoechst AG
Original Assignee
Hoechst AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoechst AG filed Critical Hoechst AG
Priority to AT84114625T priority Critical patent/ATE40333T1/de
Publication of EP0146063A2 publication Critical patent/EP0146063A2/de
Publication of EP0146063A3 publication Critical patent/EP0146063A3/de
Application granted granted Critical
Publication of EP0146063B1 publication Critical patent/EP0146063B1/de
Expired legal-status Critical Current

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Classifications

    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B65—CONVEYING; PACKING; STORING; HANDLING THIN OR FILAMENTARY MATERIAL
    • B65D—CONTAINERS FOR STORAGE OR TRANSPORT OF ARTICLES OR MATERIALS, e.g. BAGS, BARRELS, BOTTLES, BOXES, CANS, CARTONS, CRATES, DRUMS, JARS, TANKS, HOPPERS, FORWARDING CONTAINERS; ACCESSORIES, CLOSURES, OR FITTINGS THEREFOR; PACKAGING ELEMENTS; PACKAGES
    • B65D75/00—Packages comprising articles or materials partially or wholly enclosed in strips, sheets, blanks, tubes, or webs of flexible sheet material, e.g. in folded wrappers
    • B65D75/28—Articles or materials wholly enclosed in composite wrappers, i.e. wrappers formed by associating or interconnecting two or more sheets or blanks
    • B65D75/30—Articles or materials enclosed between two opposed sheets or blanks having their margins united, e.g. by pressure-sensitive adhesive, crimping, heat-sealing, or welding
    • B65D75/32—Articles or materials enclosed between two opposed sheets or blanks having their margins united, e.g. by pressure-sensitive adhesive, crimping, heat-sealing, or welding one or both sheets or blanks being recessed to accommodate contents
    • B65D75/325—Articles or materials enclosed between two opposed sheets or blanks having their margins united, e.g. by pressure-sensitive adhesive, crimping, heat-sealing, or welding one or both sheets or blanks being recessed to accommodate contents one sheet being recessed, and the other being a flat not- rigid sheet, e.g. puncturable or peelable foil
    • B65D75/327—Articles or materials enclosed between two opposed sheets or blanks having their margins united, e.g. by pressure-sensitive adhesive, crimping, heat-sealing, or welding one or both sheets or blanks being recessed to accommodate contents one sheet being recessed, and the other being a flat not- rigid sheet, e.g. puncturable or peelable foil and forming several compartments
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B65—CONVEYING; PACKING; STORING; HANDLING THIN OR FILAMENTARY MATERIAL
    • B65D—CONTAINERS FOR STORAGE OR TRANSPORT OF ARTICLES OR MATERIALS, e.g. BAGS, BARRELS, BOTTLES, BOXES, CANS, CARTONS, CRATES, DRUMS, JARS, TANKS, HOPPERS, FORWARDING CONTAINERS; ACCESSORIES, CLOSURES, OR FITTINGS THEREFOR; PACKAGING ELEMENTS; PACKAGES
    • B65D75/00—Packages comprising articles or materials partially or wholly enclosed in strips, sheets, blanks, tubes, or webs of flexible sheet material, e.g. in folded wrappers
    • B65D75/28—Articles or materials wholly enclosed in composite wrappers, i.e. wrappers formed by associating or interconnecting two or more sheets or blanks
    • B65D75/30—Articles or materials enclosed between two opposed sheets or blanks having their margins united, e.g. by pressure-sensitive adhesive, crimping, heat-sealing, or welding
    • B65D75/32—Articles or materials enclosed between two opposed sheets or blanks having their margins united, e.g. by pressure-sensitive adhesive, crimping, heat-sealing, or welding one or both sheets or blanks being recessed to accommodate contents
    • B65D75/36—Articles or materials enclosed between two opposed sheets or blanks having their margins united, e.g. by pressure-sensitive adhesive, crimping, heat-sealing, or welding one or both sheets or blanks being recessed to accommodate contents one sheet or blank being recessed and the other formed of relatively stiff flat sheet material, e.g. blister packages, the recess or recesses being preformed

Definitions

  • So-called blister packs have become established for solid pharmaceutical preparations, in which the tablets or capsules lie individually in depressions in a film, the depressions are covered with a further film and the tablets or capsules can be removed individually by pushing through the sealing film.
  • Divisible tablets have also found favor, in which the dosage of the drug can be reduced in a targeted manner by means of a notch or the like. If such divisible tablets are placed in blister packs, the problem arises of where the tablet residues should be kept safely if only a partial dose is taken. Placing the rest of the tablet back in the recess of the packaging film is unsatisfactory since the medication is not protected against falling out or contamination. Sealing with an adhesive strip is possible, but quite cumbersome, since the push-through film must first be spread over the depression again to prevent contact with the adhesive as far as possible. This procedure is not practical for elderly or disabled patients.
  • EP-A-0 084 119 shows a tablet pack in which the tablets lie in recesses in a film, the latches which are formed by the film and which are assigned to each recess are locked in place.
  • DE-A-1 486 408 discloses a similar pack, but only one cover with a plurality of latching elements corresponding to the number of depressions is provided.
  • the invention on the other hand, relates to a blister pack of the type mentioned at the beginning for divisible tablets, which is characterized in that an open recess can be reclosed with a lid. Preferred embodiments of this invention are explained in more detail below.
  • the cover is tapered conically or wedge-shaped, so that it adheres securely due to friction and / or deformation of the recess to be closed.
  • one or both of the surfaces that come into contact during the closing can improve the closing by roughening or attaching knobs, wavy lines or the like.
  • the cover and recess are connected according to the tongue-and-groove principle, with a double bead, for example, being arranged around the recess, which results in the groove into which a single bead on the cover engages as a spring.
  • These connecting elements, tongue and groove can be applied as separate elements to the blister strips and cover and glued or welded to them.
  • they are particularly advantageously worked out of the strip and lid material itself, for example by embossing or particularly advantageously by deep drawing.
  • the connecting elements between the lid and the recess are advantageously designed around the entire recess, since this ensures an airtight and watertight seal.
  • the locking elements connecting the tongue and groove can - like the parts of a push-button - be configured on the outside in a bead-like manner and have a corresponding recess (groove) on the inside.
  • the lid is firmly connected to the blister strip. This prevents the lid from being lost.
  • the connection between the blister strips and the cover can be made by one or more bands or strips, whereby the blister strips, cover and connecting element expediently consist of one piece, for example segments between the blister strips and cover are punched out, so that a more or less wide strip (or several strips) remains as a connecting element.
  • the lid is connected to the blister strip in an articulated manner, for example by a fold, so that when it rotates about this joint or in the fold, the lid comes over the depression to be closed and can be easily fixed by pressing.
  • a tab on the lid which facilitates opening.
  • This tab can also be used to fix the cover, for example by pulling it through a loop or attaching it to the strip according to the tongue and groove or push button principle.
  • the well to be closed can be filled with a tablet; however, a separate depression can also be provided as a residual tablet storage.
  • a strip with 11 wells would only be filled with 10 tablets, whereby a well at the end of the blister strip expediently remains free, to which the lid then adjoins.
  • this recess - or advantageously only its closure that is preferably the tongue or groove - can also be designed such that the joint or fold facing long side is more or less pointed. Accordingly, the "tip" of the lid points towards the tab.
  • This configuration has the advantage that when the tab is tightened, the closed memory or its closure is easier to open - initially at the "tip", which makes jerky opening easier to avoid.
  • the depressions in the blister strip are designed so that these oblong tablets are on edge.
  • Figure 1 shows a top view of the end piece of a blister strip (1), the terminal recess (2) of which has not been closed from the beginning, while the remaining recesses (3) were originally all sealed with the cover film (4), but the cover film of the last one (4) is subtracted.
  • An annular double bead (5) is arranged around the recess (2); The bead (6) engages in the groove formed in this way when the cover (7) is rotated around the fold (8).
  • the tab (9) makes it easier to open the closed tablet store.
  • (10) represents a multiply divisible tablet with notches (11).
  • (12) is a perforation line which facilitates the strip-wise removal of the cover film (4) if a depression originally filled with a tablet is to serve as residual storage.
  • the perforation line (12) can also pass through both foils, ie base foil and cover foil (4) (not shown in the figures), and then enables the packaged tablets or capsules to be “separated”.
  • FIG. 2 shows a cross section through the blister pack according to FIG. 1.

Landscapes

  • Composite Materials (AREA)
  • Engineering & Computer Science (AREA)
  • Mechanical Engineering (AREA)
  • Chemical & Material Sciences (AREA)
  • Packages (AREA)
  • Medical Preparation Storing Or Oral Administration Devices (AREA)
  • Medicinal Preparation (AREA)
  • Basic Packing Technique (AREA)
  • Medicines Containing Plant Substances (AREA)
  • Silver Salt Photography Or Processing Solution Therefor (AREA)
  • External Artificial Organs (AREA)
  • Control And Other Processes For Unpacking Of Materials (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
EP84114625A 1983-12-08 1984-12-01 Blisterpackungen fuer teilbare Tabletten Expired EP0146063B1 (de)

Priority Applications (1)

Application Number Priority Date Filing Date Title
AT84114625T ATE40333T1 (de) 1983-12-08 1984-12-01 Blisterpackungen fuer teilbare tabletten.

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE3344393 1983-12-08
DE19833344393 DE3344393A1 (de) 1983-12-08 1983-12-08 Blisterpackungen fuer teilbare tabletten

Publications (3)

Publication Number Publication Date
EP0146063A2 EP0146063A2 (de) 1985-06-26
EP0146063A3 EP0146063A3 (en) 1986-10-22
EP0146063B1 true EP0146063B1 (de) 1989-01-25

Family

ID=6216363

Family Applications (1)

Application Number Title Priority Date Filing Date
EP84114625A Expired EP0146063B1 (de) 1983-12-08 1984-12-01 Blisterpackungen fuer teilbare Tabletten

Country Status (19)

Country Link
EP (1) EP0146063B1 (fi)
JP (1) JPS60158058A (fi)
KR (1) KR850004238A (fi)
AT (1) ATE40333T1 (fi)
AU (1) AU575099B2 (fi)
CA (1) CA1246501A (fi)
DE (2) DE3344393A1 (fi)
DK (1) DK161588C (fi)
ES (1) ES293458Y (fi)
FI (1) FI80655C (fi)
GR (1) GR81201B (fi)
HU (1) HU189951B (fi)
IE (1) IE56216B1 (fi)
IL (1) IL73758A (fi)
MX (1) MX162000A (fi)
NO (1) NO162505C (fi)
NZ (1) NZ210453A (fi)
PT (1) PT79624B (fi)
ZA (1) ZA849538B (fi)

Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0148118A2 (en) * 1983-12-09 1985-07-10 Sandoz Ag Package
GB2222566A (en) * 1988-09-12 1990-03-14 Ici Plc A tablet blister pack and dispenser device
EP1006054A1 (fr) 1998-12-01 2000-06-07 Aventis Pharma S.A. Emballage du type "blister"
US6345717B1 (en) 1995-12-07 2002-02-12 Smithkline Beecham Plc Reinforced blister pack

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE29804383U1 (de) 1998-03-12 1998-05-14 Klocke Verpackungs-Service GmbH, 76356 Weingarten Verpackung, insbesondere für Produkte in Tablettenform
WO2015114749A1 (ja) * 2014-01-29 2015-08-06 株式会社モリモト医薬 服用物収容セル、ストリップ包装体、及び、服用物収容セルの製造方法

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0148118A2 (en) * 1983-12-09 1985-07-10 Sandoz Ag Package

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1099499A (en) * 1964-11-26 1968-01-17 Aspro Nicholas Ltd Improvements relating to the packaging of tablets
DE1486408A1 (de) * 1965-08-30 1969-04-17 Hoefliger & Karg Aufreisspackung
CH559127A5 (fi) * 1972-12-22 1975-02-28 Artusi A B
DE2714877A1 (de) * 1977-04-02 1978-10-12 Uhlmann Maschf Josef Durchdrueckpackung fuer kleinteile, insbesondere tabletten oder dergleichen
DE2917108A1 (de) * 1979-04-27 1980-11-06 Helmut Zanker Verpackung fuer arzneimittel
DE3201244A1 (de) * 1982-01-16 1983-07-28 pfm Plastik für die Medizin GmbH, 5000 Köln "medikamentenspender"

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0148118A2 (en) * 1983-12-09 1985-07-10 Sandoz Ag Package

Cited By (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0148118A2 (en) * 1983-12-09 1985-07-10 Sandoz Ag Package
EP0148118A3 (en) * 1983-12-09 1986-10-29 Sandoz Ag Package
GB2222566A (en) * 1988-09-12 1990-03-14 Ici Plc A tablet blister pack and dispenser device
US5110007A (en) * 1988-09-12 1992-05-05 Imperial Chemical Industries Plc Dispenser
GB2222566B (en) * 1988-09-12 1993-04-14 Ici Plc Blister packs and methods of loading such packs
US6345717B1 (en) 1995-12-07 2002-02-12 Smithkline Beecham Plc Reinforced blister pack
EP1006054A1 (fr) 1998-12-01 2000-06-07 Aventis Pharma S.A. Emballage du type "blister"

Also Published As

Publication number Publication date
FI80655C (fi) 1990-07-10
FI844798A0 (fi) 1984-12-05
PT79624A (de) 1985-01-01
AU3642484A (en) 1985-06-13
IE56216B1 (en) 1991-05-22
ZA849538B (en) 1985-07-31
FI844798L (fi) 1985-06-09
DK588184A (da) 1985-06-09
FI80655B (fi) 1990-03-30
MX162000A (es) 1991-03-19
EP0146063A3 (en) 1986-10-22
NZ210453A (en) 1988-07-28
DK588184D0 (da) 1984-12-07
CA1246501A (en) 1988-12-13
EP0146063A2 (de) 1985-06-26
ES293458Y (es) 1987-04-16
DK161588B (da) 1991-07-22
NO844912L (no) 1985-06-10
HU189951B (en) 1986-08-28
IE843144L (en) 1985-06-08
DE3476373D1 (en) 1989-03-02
IL73758A0 (en) 1985-03-31
HUT37096A (en) 1985-11-28
JPS60158058A (ja) 1985-08-19
ES293458U (es) 1986-08-01
NO162505C (no) 1990-01-10
PT79624B (de) 1986-10-20
DE3344393A1 (de) 1985-06-20
DK161588C (da) 1992-01-06
AU575099B2 (en) 1988-07-21
NO162505B (no) 1989-10-02
GR81201B (en) 1985-04-03
IL73758A (en) 1988-09-30
KR850004238A (ko) 1985-07-11
ATE40333T1 (de) 1989-02-15

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