EG25884A - Glycopeptide deriveatives as antibiotic - Google Patents

Glycopeptide deriveatives as antibiotic

Info

Publication number
EG25884A
EG25884A EG54495A EG54495A EG25884A EG 25884 A EG25884 A EG 25884A EG 54495 A EG54495 A EG 54495A EG 54495 A EG54495 A EG 54495A EG 25884 A EG25884 A EG 25884A
Authority
EG
Egypt
Prior art keywords
antibiotic
deriveatives
glycopeptide
mixed
components
Prior art date
Application number
EG54495A
Other languages
English (en)
Inventor
Robin D G Cooper
Bret Eugene Huff
Thalia I Nicas
John Thomas Quatroche
Michael J Rodriguez
Nancy J Snyder
Michael Alexander Staszak
Richard C Thompson
Stephen C Wilkie
Mark James Zweifel
Original Assignee
Lilly Co Eli
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Lilly Co Eli filed Critical Lilly Co Eli
Application granted granted Critical
Publication of EG25884A publication Critical patent/EG25884A/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/50—Cyclic peptides containing at least one abnormal peptide link
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K9/00—Peptides having up to 20 amino acids, containing saccharide radicals and having a fully defined sequence; Derivatives thereof
    • C07K9/006—Peptides having up to 20 amino acids, containing saccharide radicals and having a fully defined sequence; Derivatives thereof the peptide sequence being part of a ring structure
    • C07K9/008—Peptides having up to 20 amino acids, containing saccharide radicals and having a fully defined sequence; Derivatives thereof the peptide sequence being part of a ring structure directly attached to a hetero atom of the saccharide radical, e.g. actaplanin, avoparcin, ristomycin, vancomycin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K9/00—Peptides having up to 20 amino acids, containing saccharide radicals and having a fully defined sequence; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Oncology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Communicable Diseases (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Immunology (AREA)
  • Epidemiology (AREA)
  • Peptides Or Proteins (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Compounds Of Unknown Constitution (AREA)
  • Indole Compounds (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Saccharide Compounds (AREA)
EG54495A 1994-01-28 1995-07-06 Glycopeptide deriveatives as antibiotic EG25884A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US18939394A 1994-01-28 1994-01-28
US35641394A 1994-12-15 1994-12-15

Publications (1)

Publication Number Publication Date
EG25884A true EG25884A (en) 2012-09-24

Family

ID=26885101

Family Applications (1)

Application Number Title Priority Date Filing Date
EG54495A EG25884A (en) 1994-01-28 1995-07-06 Glycopeptide deriveatives as antibiotic

Country Status (30)

Country Link
US (1) US5843889A (sl)
EP (3) EP1031576B1 (sl)
JP (1) JP3756539B2 (sl)
KR (1) KR100388867B1 (sl)
CN (1) CN1071334C (sl)
AT (3) ATE248856T1 (sl)
AU (1) AU703106B2 (sl)
BR (1) BR9500365A (sl)
CA (3) CA2546625C (sl)
CO (1) CO4600679A1 (sl)
CZ (2) CZ292895B6 (sl)
DE (3) DE69532013T2 (sl)
DK (3) DK1016670T3 (sl)
EG (1) EG25884A (sl)
ES (3) ES2204444T3 (sl)
FI (3) FI117095B (sl)
HU (1) HU225164B1 (sl)
IL (1) IL112457A (sl)
MY (1) MY128335A (sl)
NO (1) NO323103B1 (sl)
NZ (1) NZ270387A (sl)
PE (1) PE40996A1 (sl)
PL (1) PL180961B1 (sl)
PT (3) PT1016670E (sl)
RU (1) RU2145609C1 (sl)
SG (1) SG52719A1 (sl)
SI (2) SI0667353T1 (sl)
TW (1) TW457248B (sl)
UA (1) UA43323C2 (sl)
YU (1) YU4995A (sl)

Families Citing this family (51)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5840684A (en) * 1994-01-28 1998-11-24 Eli Lilly And Company Glycopeptide antibiotic derivatives
US5919756A (en) * 1996-06-28 1999-07-06 Eli Lilly And Company Amides
US5952466A (en) * 1997-11-12 1999-09-14 Eli Lilly And Company Reductive alkylation of glycopeptide antibiotics
US5939382A (en) * 1996-11-21 1999-08-17 Eli Lilly And Company Reducing agent for reductive alkylation of glycopeptide antibiotics
ID18900A (id) * 1996-11-21 1998-05-20 Lilly Co Eli Alkilasi menurun dari gliko peptida anti biotik
US5977063A (en) * 1997-05-20 1999-11-02 Eli Lilly And Company Alkylated hexapeptides
US5952310A (en) * 1997-05-20 1999-09-14 Eli Lilly And Company Glycopeptide hexapeptides
US5919771A (en) * 1997-05-20 1999-07-06 Eli Lilly And Company Urea and thiourea derivatives of glycopeptides
US5994297A (en) * 1997-08-22 1999-11-30 Eli Lilly And Company Therapy for Staphylococcus aureus
US6518242B1 (en) 1998-02-20 2003-02-11 Theravance, Inc. Derivatives of glycopeptide antibacterial agents
JP4307723B2 (ja) 1998-05-01 2009-08-05 イーライ リリー アンド カンパニー Ｎ１−修飾グリコペプチド
WO2000004044A1 (en) * 1998-07-14 2000-01-27 Princeton University Glycopeptide antibiotics, combinatorial libraries of glycopeptide antibiotics and methods of producing same
US6710168B1 (en) 1999-05-19 2004-03-23 The Trustees Of The University Of Princeton Glycopeptide antibiotics, combinatorial libraries of glycopeptide antibiotics and methods of producing same
WO2000039156A1 (en) * 1998-12-23 2000-07-06 Advanced Medicine, Inc. Glycopeptide derivatives and pharmaceutical compositions containing the same
WO2001081373A2 (en) * 2000-04-25 2001-11-01 Merck & Co., Inc. Glycopeptide antibacterial compounds and methods of using same
AU2001259306A1 (en) 2000-05-02 2001-11-12 Advanced Medicine, Inc. Pharmaceutical compositions containing a glycopeptide antibiotic and a cyclodextrin
AU2001259298A1 (en) 2000-05-02 2001-11-12 Advanced Medicine, Inc. Polyacid glycopeptide derivatives
EP1276759B1 (en) * 2000-05-02 2008-07-30 Theravance, Inc. Reductive alkylation process on glycopeptides
WO2001098327A2 (en) 2000-06-22 2001-12-27 Theravance, Inc. Glycopeptide carboxy-saccharide derivatives
UA75083C2 (uk) 2000-06-22 2006-03-15 Тераванс, Інк. Похідні глікопептидфосфонатів
WO2001098329A1 (en) 2000-06-22 2001-12-27 Theravance, Inc. Polyhydroxy glycopeptide derivatives
US6872804B2 (en) 2000-06-22 2005-03-29 Theravance, Inc. Glycopeptide disulfide and thioester derivatives
TWI275594B (en) 2001-08-24 2007-03-11 Theravance Inc Process for preparing vancomycin phosphonate derivatives
TWI312785B (en) 2001-08-24 2009-08-01 Theravance Inc Process for preparing vancomycin derivatives
TWI233932B (en) * 2001-08-24 2005-06-11 Theravance Inc Process for purifying glycopeptide phosphonate derivatives
CA2497159A1 (en) * 2002-08-30 2004-03-11 K.U. Leuven Research And Development Glycopeptide antibiotic and semisynthetic derivatives thereof and their use as antiviral agents
EP1624858B1 (en) 2003-04-09 2018-06-06 Rutgers, the State University of New Jersey Novel encochleation methods
WO2004110473A1 (en) 2003-05-27 2004-12-23 Theravance, Inc. Use of a polyene macrolide antifungal agent in combination with a glycopeptide antibacterial agent
EP1654036B1 (en) 2003-07-22 2007-12-26 Theravance, Inc. Use of an echinocandin antifungal agent in combination with a glycopeptide antibacterial agent
CA2588285A1 (en) 2004-11-29 2006-06-01 National University Corporation Nagoya University Glycopeptide antibiotic monomer derivatives
US7632918B2 (en) 2005-02-28 2009-12-15 Novartis Vaccines And Diagnostics, Inc. Semi-synthetic glycopeptides with antibiotic activity
BRPI0612326A2 (pt) 2005-04-01 2010-11-03 Buckeye Technologies Inc material não tecido, painel do material não tecido, construção isolante térmica, laminado atenuador de som, painel do laminado atenuador, pacote para um objeto, processo para a produção de um material não tecido, processo para prover atenuação de som ou isolamento térmico, artigo isolante térmico moldado, artigo isolante de veìculo, artigo isolante atenuador de som, artigo moldado, estrutura não tecida, processo para a produção de uma estrutura não tecida, e veìculo motorizado
CA2623198C (en) 2005-09-22 2014-08-05 Medivas, Llc Bis-(a-amino)-diol-diester-containing poly(ester amide) and poly(ester urethane) compositions and methods of use
CA2623239C (en) 2005-09-22 2016-07-12 Medivas, Llc Solid polymer delivery compositions and methods for use thereof
TW200808818A (en) 2006-05-26 2008-02-16 Shionogi & Co Glycopeptide antibiotic derivatives
CN101959900A (zh) 2007-12-26 2011-01-26 盐野义制药株式会社 糖肽类抗生素糖基化衍生物
US8841440B2 (en) 2008-04-01 2014-09-23 Cornell University Organo-soluble chitosan salts and chitosan-derived biomaterials prepared thereof
CN101343313B (zh) * 2008-09-03 2011-11-16 南京农业大学 一种葡萄糖二肽类化合物及其制备方法和用途
CA2834788C (en) 2011-05-05 2020-11-17 Coordinated Program Development, Llc Cochleate compositions and methods of making and using same
CN104418941B (zh) * 2013-08-19 2017-11-07 爱斯医药科技(南京)有限公司 万古霉素衍生物、制备方法及其应用
CA2925005A1 (en) 2013-09-23 2015-03-26 Jawaharlal Nehru Centre for Advanced Scientific Research (JNCASR) Vancomycin-sugar conjugates and uses thereof
JP6712991B2 (ja) * 2014-07-17 2020-06-24 ザ メディシンズ カンパニー 高純度のオリタバンシン及びその製造方法
NZ731955A (en) 2014-11-06 2023-07-28 Xellia Pharmaceuticals Aps Glycopeptide compositions
CA2972276A1 (en) * 2014-12-25 2016-06-30 Jawaharlal Nehru Centre for Advanced Scientific Research (JNCASR) Glycopeptides and uses thereof
CN106188243B (zh) * 2015-05-05 2020-06-26 博瑞生物医药（苏州）股份有限公司 一种奥利万星的制备方法
CN106467570B (zh) * 2015-08-14 2020-04-07 正大天晴药业集团股份有限公司 糖肽类抗生素的还原烷基化方法
CN107434823B (zh) * 2016-05-26 2021-11-16 江苏恒瑞医药股份有限公司 一种奥利万星中间体a82846b的纯化方法
CN108409837B (zh) * 2018-03-06 2021-09-24 上海来益生物药物研究开发中心有限责任公司 一组具有抗耐药性细菌活性的糖肽类化合物、其制备方法和应用
CN109053864B (zh) * 2018-07-10 2021-08-24 丽珠集团新北江制药股份有限公司 一种制备奥利万星的方法
CN109053865B (zh) * 2018-07-20 2021-04-13 丽珠集团新北江制药股份有限公司 一种羧基保护制备奥利万星的方法
US20230218644A1 (en) 2020-04-16 2023-07-13 Som Innovation Biotech, S.A. Compounds for use in the treatment of viral infections by respiratory syndrome-related coronavirus

Family Cites Families (22)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3067099A (en) * 1955-09-16 1962-12-04 Lilly Co Eli Vancomycin and method for its preparation
US3338786A (en) * 1966-07-29 1967-08-29 American Cyanamid Co Antibiotic av290 and production thereof
US4552886A (en) * 1982-06-07 1985-11-12 Eli Lilly And Company Fungicidal pyridylmethyl-amines
IT1173329B (it) * 1984-02-21 1987-06-24 Lepetit Spa Procedimento per la trasformazione quantitativa di teicoplanina a2 fattore 1 in teicoplanina a2 fattore 3
GB8415093D0 (en) * 1984-06-13 1984-07-18 Lepetit Spa Antibiotic l 17392
US4698327A (en) * 1985-04-25 1987-10-06 Eli Lilly And Company Novel glycopeptide derivatives
IL78597A0 (en) * 1985-04-25 1986-08-31 Lilly Co Eli Novel glycopeptide derivatives
US4643987A (en) * 1985-08-14 1987-02-17 Eli Lilly And Company Modified glycopeptides
US4639433A (en) * 1985-08-14 1987-01-27 Eli Lilly And Company Glycopeptide derivatives
US4946941A (en) * 1986-01-24 1990-08-07 Shionogi & Co., Ltd. Novel glycopeptide antibiotics
EG18377A (en) * 1986-09-19 1993-04-30 Lilly Co Eli Process for preparing glycopeptide antibiotics
GB8701872D0 (en) * 1987-01-28 1987-03-04 Lepetit Spa N15-alkyl & n15,n15-dialkyl derivatives
US5071749A (en) * 1987-04-16 1991-12-10 Shionogi & Co., Ltd. Glycopetide antibiotic pa-45052-b
GB8726859D0 (en) * 1987-11-17 1987-12-23 Lepetit Spa 22-dechlorotei-coplanins
DK203089A (da) * 1988-04-28 1989-10-29 Beecham Group Plc Metaboliter
CA1339808C (en) * 1988-10-19 1998-04-07 Manuel Debono Glycopeptide antibiotics
US5194424A (en) * 1988-12-27 1993-03-16 Gruppo Lepetit Spa C63 -amide derivatives of 34-de(acetylglucosaminyl)-34-deoxy-teicoplanin and their use as medicaments against bacteria resistant to glycopeptide antibiotics
US5185320A (en) * 1989-04-03 1993-02-09 Gruppo Lepetit S.P.A. O56 -alkyl derivatives of aglycone and pseudo aglycones of teicoplanin
DE69001241T2 (de) * 1989-12-11 1993-07-22 De Beers Ind Diamond Schleifprodukte.
IL96603A (en) * 1989-12-13 1998-02-08 Lilly Co Eli Antibacterial glycopeptide derivativesProcess for their preparation and pharmaceutical preparations containing the same
US5187082A (en) * 1990-08-16 1993-02-16 Eli Lilly And Company Process for producing A83850 antibiotics
RU2125058C1 (ru) * 1991-07-29 1999-01-20 Группо Лепетит С.П.А. Производное антибиотика а 40926, способы его получения, фармацевтическая композиция

Also Published As

Publication number Publication date
SI1016670T1 (sl) 2004-02-29
EP1031576B1 (en) 2004-05-06
ATE248856T1 (de) 2003-09-15
DE69533004T2 (de) 2005-04-07
JPH07258289A (ja) 1995-10-09
PL306976A1 (en) 1995-08-07
CZ292895B6 (cs) 2003-12-17
IL112457A (en) 2004-06-20
SI0667353T1 (sl) 2004-04-30
PT667353E (pt) 2004-03-31
NO950298D0 (no) 1995-01-26
HU9500230D0 (en) 1995-03-28
NO323103B1 (no) 2007-01-02
PE40996A1 (es) 1996-10-14
FI117095B (fi) 2006-06-15
CZ292921B6 (cs) 2004-01-14
JP3756539B2 (ja) 2006-03-15
DE69531709T2 (de) 2004-07-15
CA2546625A1 (en) 1995-07-29
ES2204444T3 (es) 2004-05-01
FI117096B (fi) 2006-06-15
DE69532013D1 (de) 2003-12-04
DK1031576T3 (da) 2004-08-16
NZ270387A (en) 1996-11-26
TW457248B (en) 2001-10-01
RU95101039A (ru) 1996-10-27
DK1016670T3 (da) 2004-01-05
YU4995A (sh) 1998-07-10
KR950032274A (ko) 1995-12-20
CA2141106C (en) 2007-01-23
CA2546910A1 (en) 1995-07-29
KR100388867B1 (ko) 2003-10-08
BR9500365A (pt) 1995-10-17
DK0667353T3 (da) 2004-03-22
US5843889A (en) 1998-12-01
ATE266042T1 (de) 2004-05-15
EP0667353A1 (en) 1995-08-16
EP0667353B1 (en) 2003-10-29
ES2220335T3 (es) 2004-12-16
UA43323C2 (uk) 2001-12-17
FI117097B (fi) 2006-06-15
AU1138995A (en) 1995-08-10
CN1119649A (zh) 1996-04-03
FI20050513A (fi) 2005-05-13
ES2210274T3 (es) 2004-07-01
CA2141106A1 (en) 1995-07-29
EP1016670B1 (en) 2003-09-03
SG52719A1 (en) 1998-09-28
DE69532013T2 (de) 2004-07-08
CA2546910C (en) 2010-09-14
ATE253077T1 (de) 2003-11-15
DE69531709D1 (de) 2003-10-09
PT1016670E (pt) 2003-12-31
NO950298L (no) 1995-07-31
EP1016670A1 (en) 2000-07-05
HU225164B1 (en) 2006-07-28
EP1031576A2 (en) 2000-08-30
DE69533004D1 (de) 2004-06-09
IL112457A0 (en) 1995-03-30
EP1031576A3 (en) 2000-12-27
HUT68715A (en) 1995-07-28
MY128335A (en) 2007-01-31
CZ18495A3 (en) 1995-08-16
CA2546625C (en) 2008-09-09
PL180961B1 (pl) 2001-05-31
RU2145609C1 (ru) 2000-02-20
FI950374A (fi) 1995-07-29
FI950374A0 (fi) 1995-01-27
CN1071334C (zh) 2001-09-19
AU703106B2 (en) 1999-03-18
FI20050512A (fi) 2005-05-13
CO4600679A1 (es) 1998-05-08
PT1031576E (pt) 2004-08-31

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