EG23203A - Technical process for the manufacture of tropenol. - Google Patents
Technical process for the manufacture of tropenol.Info
- Publication number
- EG23203A EG23203A EG2002060738A EG2002060738A EG23203A EG 23203 A EG23203 A EG 23203A EG 2002060738 A EG2002060738 A EG 2002060738A EG 2002060738 A EG2002060738 A EG 2002060738A EG 23203 A EG23203 A EG 23203A
- Authority
- EG
- Egypt
- Prior art keywords
- tropenol
- manufacture
- technical process
- technical
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D451/00—Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof
- C07D451/02—Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof containing not further condensed 8-azabicyclo [3.2.1] octane or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane; Cyclic acetals thereof
- C07D451/04—Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof containing not further condensed 8-azabicyclo [3.2.1] octane or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane; Cyclic acetals thereof with hetero atoms directly attached in position 3 of the 8-azabicyclo [3.2.1] octane or in position 7 of the 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring system
- C07D451/06—Oxygen atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/08—Bronchodilators
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D451/00—Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof
- C07D451/02—Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof containing not further condensed 8-azabicyclo [3.2.1] octane or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane; Cyclic acetals thereof
- C07D451/04—Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof containing not further condensed 8-azabicyclo [3.2.1] octane or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane; Cyclic acetals thereof with hetero atoms directly attached in position 3 of the 8-azabicyclo [3.2.1] octane or in position 7 of the 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring system
- C07D451/06—Oxygen atoms
- C07D451/10—Oxygen atoms acylated by aliphatic or araliphatic carboxylic acids, e.g. atropine, scopolamine
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Life Sciences & Earth Sciences (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Engineering & Computer Science (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Biomedical Technology (AREA)
- Neurosurgery (AREA)
- Neurology (AREA)
- Pulmonology (AREA)
- Pain & Pain Management (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Lock And Its Accessories (AREA)
- Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Catalysts (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DE10131200 | 2001-06-28 |
Publications (1)
Publication Number | Publication Date |
---|---|
EG23203A true EG23203A (en) | 2004-07-31 |
Family
ID=7689774
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
EG2002060738A EG23203A (en) | 2001-06-28 | 2002-06-26 | Technical process for the manufacture of tropenol. |
Country Status (41)
Country | Link |
---|---|
US (1) | US6610849B2 (bs) |
EP (3) | EP1475379B1 (bs) |
JP (2) | JP4485192B2 (bs) |
KR (3) | KR100886342B1 (bs) |
CN (2) | CN1982309B (bs) |
AR (1) | AR039056A1 (bs) |
AT (3) | ATE359285T1 (bs) |
AU (2) | AU2002257820B2 (bs) |
BG (2) | BG66398B1 (bs) |
BR (1) | BR0210664B1 (bs) |
CA (1) | CA2451573C (bs) |
CO (1) | CO5650166A2 (bs) |
CY (1) | CY1107681T1 (bs) |
CZ (1) | CZ296187B6 (bs) |
DE (2) | DE50209948D1 (bs) |
DK (3) | DK1808435T3 (bs) |
EA (2) | EA009808B1 (bs) |
EC (1) | ECSP034927A (bs) |
EE (1) | EE05403B1 (bs) |
EG (1) | EG23203A (bs) |
ES (3) | ES2242022T3 (bs) |
HK (2) | HK1068613A1 (bs) |
HR (2) | HRP20031085B1 (bs) |
HU (2) | HU230379B1 (bs) |
IL (2) | IL159239A0 (bs) |
ME (1) | MEP42608A (bs) |
MX (1) | MXPA03011516A (bs) |
MY (1) | MY122932A (bs) |
NO (1) | NO328154B1 (bs) |
NZ (2) | NZ541395A (bs) |
PE (1) | PE20030123A1 (bs) |
PL (1) | PL209520B1 (bs) |
PT (2) | PT1404673E (bs) |
RS (1) | RS50436B (bs) |
SA (1) | SA02230194B1 (bs) |
SI (2) | SI1404673T1 (bs) |
SK (1) | SK288022B6 (bs) |
TW (1) | TW574220B (bs) |
UA (2) | UA76761C2 (bs) |
WO (1) | WO2003002562A1 (bs) |
ZA (1) | ZA200308895B (bs) |
Families Citing this family (12)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE10141377A1 (de) | 2001-08-23 | 2003-03-13 | Boehringer Ingelheim Pharma | Aufstreuverfahren zur Herstellung von Pulverformulierungen |
US6747153B2 (en) * | 2002-05-31 | 2004-06-08 | Boehringer Ingelheim Pharma Gmbh & Co. Kg | Industrial process for preparing tropenol |
US20090162562A1 (en) * | 2007-12-24 | 2009-06-25 | Bangalore Aswatha Nagaraj | Methods for Applying Thermal Barrier Coating Systems |
WO2009087419A1 (en) * | 2008-01-10 | 2009-07-16 | Generics [Uk] Limited | Novel process for the preparation of scopine esters |
WO2011015884A1 (en) | 2009-08-07 | 2011-02-10 | Generics [Uk] Limited | Process to prepare scopine esters |
AU2010280497B2 (en) | 2009-08-07 | 2015-10-22 | Generics [Uk] Limited | Anhydrate of tiotropium bromide |
CN102351856B (zh) * | 2011-08-24 | 2013-05-01 | 商丘市韶华药业有限公司 | 一种α-托品醇的纯化方法 |
ITRM20110508A1 (it) | 2011-09-27 | 2013-03-28 | Lusochimica Spa | Processo per la preparazione degli esteri della scopina. |
RS55996B1 (sr) * | 2011-12-22 | 2017-09-29 | Cerbios-Pharma S A | Kontinuirani postupak za alkilaciju cikličnih tercijarnih amina |
CN113292574B (zh) * | 2020-02-21 | 2022-05-03 | 四川大学 | 一类手性多环的托品烷化合物及其制备方法和用途 |
CN111269226B (zh) * | 2020-04-13 | 2021-09-21 | 石家庄四药有限公司 | 异丙托溴铵的合成方法 |
CN113264929B (zh) * | 2021-05-02 | 2023-10-10 | 润生药业有限公司 | 一种噻托溴铵的制备方法 |
Family Cites Families (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE3931041C2 (de) * | 1989-09-16 | 2000-04-06 | Boehringer Ingelheim Kg | Ester von Thienylcarbonsäuren mit Aminoalkoholen, ihre Quaternierungsprodukte, Verfahren zu ihrer Herstellung und diese enthaltende Arzneimittel |
WO1995028401A1 (en) * | 1994-04-19 | 1995-10-26 | Neurosearch A/S | Tropane-2-aldoxine derivatives as neurotransmitter reuptake inhibitors |
DE19515625C2 (de) * | 1995-04-28 | 1998-02-19 | Boehringer Ingelheim Kg | Verfahren zur Herstellung von enantiomerenreinen Tropasäureestern |
-
2002
- 2002-06-03 US US10/160,702 patent/US6610849B2/en not_active Expired - Lifetime
- 2002-06-08 KR KR1020087014692A patent/KR100886342B1/ko active IP Right Grant
- 2002-06-08 PT PT02727610T patent/PT1404673E/pt unknown
- 2002-06-08 CN CN2006101604057A patent/CN1982309B/zh not_active Expired - Lifetime
- 2002-06-08 RS YUP-1011/03A patent/RS50436B/sr unknown
- 2002-06-08 CA CA2451573A patent/CA2451573C/en not_active Expired - Fee Related
- 2002-06-08 PL PL366942A patent/PL209520B1/pl unknown
- 2002-06-08 EA EA200501081A patent/EA009808B1/ru not_active IP Right Cessation
- 2002-06-08 EP EP04018550A patent/EP1475379B1/de not_active Revoked
- 2002-06-08 ME MEP-426/08A patent/MEP42608A/bs unknown
- 2002-06-08 EP EP02727610A patent/EP1404673B1/de not_active Expired - Lifetime
- 2002-06-08 KR KR1020037017010A patent/KR100866272B1/ko active IP Right Grant
- 2002-06-08 JP JP2003508943A patent/JP4485192B2/ja not_active Expired - Lifetime
- 2002-06-08 AT AT04018550T patent/ATE359285T1/de active
- 2002-06-08 ES ES02727610T patent/ES2242022T3/es not_active Expired - Lifetime
- 2002-06-08 SK SK66-2004A patent/SK288022B6/sk not_active IP Right Cessation
- 2002-06-08 CN CNB028128672A patent/CN1288154C/zh not_active Expired - Lifetime
- 2002-06-08 EE EEP200400045A patent/EE05403B1/xx not_active IP Right Cessation
- 2002-06-08 NZ NZ541395A patent/NZ541395A/en not_active IP Right Cessation
- 2002-06-08 SI SI200230153T patent/SI1404673T1/xx unknown
- 2002-06-08 AT AT07101821T patent/ATE527257T1/de active
- 2002-06-08 CZ CZ20040149A patent/CZ296187B6/cs not_active IP Right Cessation
- 2002-06-08 NZ NZ530770A patent/NZ530770A/en not_active IP Right Cessation
- 2002-06-08 DK DK07101821.2T patent/DK1808435T3/da active
- 2002-06-08 EA EA200301292A patent/EA006393B1/ru not_active IP Right Cessation
- 2002-06-08 AT AT02727610T patent/ATE294801T1/de active
- 2002-06-08 DK DK04018550T patent/DK1475379T3/da active
- 2002-06-08 ES ES07101821T patent/ES2374981T3/es not_active Expired - Lifetime
- 2002-06-08 BR BRPI0210664-7B1A patent/BR0210664B1/pt active IP Right Grant
- 2002-06-08 MX MXPA03011516A patent/MXPA03011516A/es active IP Right Grant
- 2002-06-08 DE DE50209948T patent/DE50209948D1/de not_active Expired - Lifetime
- 2002-06-08 SI SI200230540T patent/SI1475379T1/sl unknown
- 2002-06-08 IL IL15923902A patent/IL159239A0/xx unknown
- 2002-06-08 WO PCT/EP2002/006290 patent/WO2003002562A1/de active Application Filing
- 2002-06-08 DE DE50203015T patent/DE50203015D1/de not_active Expired - Lifetime
- 2002-06-08 HU HU1400554A patent/HU230379B1/hu unknown
- 2002-06-08 EP EP07101821A patent/EP1808435B1/de not_active Expired - Lifetime
- 2002-06-08 AU AU2002257820A patent/AU2002257820B2/en not_active Expired
- 2002-06-08 ES ES04018550T patent/ES2285318T3/es not_active Expired - Lifetime
- 2002-06-08 DK DK02727610T patent/DK1404673T3/da active
- 2002-06-08 PT PT04018550T patent/PT1475379E/pt unknown
- 2002-06-08 HU HU0400332A patent/HU230036B1/hu unknown
- 2002-06-25 PE PE2002000553A patent/PE20030123A1/es not_active Application Discontinuation
- 2002-06-26 EG EG2002060738A patent/EG23203A/xx active
- 2002-06-26 MY MYPI20022420A patent/MY122932A/en unknown
- 2002-06-26 TW TW91114026A patent/TW574220B/zh not_active IP Right Cessation
- 2002-06-28 AR ARP020102453A patent/AR039056A1/es active Pending
- 2002-07-10 SA SA2230194A patent/SA02230194B1/ar unknown
- 2002-08-06 UA UA2004010605A patent/UA76761C2/uk unknown
-
2003
- 2003-03-28 KR KR10-2003-0019708A patent/KR100530661B1/ko not_active IP Right Cessation
- 2003-11-14 ZA ZA200308895A patent/ZA200308895B/en unknown
- 2003-12-08 IL IL159239A patent/IL159239A/en active IP Right Grant
- 2003-12-17 BG BG108462A patent/BG66398B1/bg active Active
- 2003-12-17 NO NO20035633A patent/NO328154B1/no not_active IP Right Cessation
- 2003-12-23 CO CO03112174A patent/CO5650166A2/es active IP Right Grant
- 2003-12-24 HR HR20031085A patent/HRP20031085B1/xx not_active IP Right Cessation
- 2003-12-24 EC EC2003004927A patent/ECSP034927A/es unknown
-
2005
- 2005-01-29 HK HK05100781A patent/HK1068613A1/xx not_active IP Right Cessation
-
2006
- 2006-03-09 UA UAA200602562A patent/UA86031C2/ru unknown
-
2007
- 2007-06-21 CY CY20071100822T patent/CY1107681T1/el unknown
- 2007-10-31 HK HK07111732.3A patent/HK1103404A1/xx not_active IP Right Cessation
-
2008
- 2008-04-08 AU AU2008201565A patent/AU2008201565B2/en not_active Expired
-
2009
- 2009-02-23 HR HR20090110A patent/HRP20090110A2/xx not_active Application Discontinuation
- 2009-10-13 JP JP2009236400A patent/JP2010043116A/ja active Pending
-
2013
- 2013-05-07 BG BG10111461A patent/BG111461A/en active Pending
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