EE9800378A - Alküülaminobensotiasooli ja -bensoksasooli derivaadid - Google Patents

Alküülaminobensotiasooli ja -bensoksasooli derivaadid

Info

Publication number
EE9800378A
EE9800378A EE9800378A EE9800378A EE9800378A EE 9800378 A EE9800378 A EE 9800378A EE 9800378 A EE9800378 A EE 9800378A EE 9800378 A EE9800378 A EE 9800378A EE 9800378 A EE9800378 A EE 9800378A
Authority
EE
Estonia
Prior art keywords
alkylaminobenzothiazole
benzoxazole derivatives
benzoxazole
derivatives
Prior art date
Application number
EE9800378A
Other languages
English (en)
Other versions
EE03563B1 (et
Inventor
Edmond Josephine Kennis Ludo
Carolus Mertens Josephus
Maria Aloysius Pieters Serge
Original Assignee
Janssen Pharmaceutica N.V.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Janssen Pharmaceutica N.V. filed Critical Janssen Pharmaceutica N.V.
Publication of EE9800378A publication Critical patent/EE9800378A/et
Publication of EE03563B1 publication Critical patent/EE03563B1/et

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D263/00—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings
    • C07D263/52—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings condensed with carbocyclic rings or ring systems
    • C07D263/54—Benzoxazoles; Hydrogenated benzoxazoles
    • C07D263/58—Benzoxazoles; Hydrogenated benzoxazoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached in position 2
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/42—Oxazoles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
    • C07B59/00—Introduction of isotopes of elements into organic compounds ; Labelled organic compounds per se
    • C07B59/002—Heterocyclic compounds
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
    • C07D277/60—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings condensed with carbocyclic rings or ring systems
    • C07D277/62—Benzothiazoles
    • C07D277/68—Benzothiazoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached in position 2
    • C07D277/82—Nitrogen atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Psychiatry (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Thiazole And Isothizaole Compounds (AREA)
EE9800378A 1996-05-10 1997-05-02 Alküülaminobensotiasooli ja -bensoksasooli derivaadid EE03563B1 (et)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP96201282 1996-05-10
PCT/EP1997/002505 WO1997043271A1 (en) 1996-05-10 1997-05-02 Alkylaminobenzothiazole and -benzoxazole derivatives

Publications (2)

Publication Number Publication Date
EE9800378A true EE9800378A (et) 1999-04-15
EE03563B1 EE03563B1 (et) 2001-12-17

Family

ID=8223970

Family Applications (1)

Application Number Title Priority Date Filing Date
EE9800378A EE03563B1 (et) 1996-05-10 1997-05-02 Alküülaminobensotiasooli ja -bensoksasooli derivaadid

Country Status (29)

Country Link
US (2) US6103725A (et)
EP (2) EP0912533B1 (et)
JP (1) JP3237759B2 (et)
KR (1) KR100330699B1 (et)
CN (1) CN1074766C (et)
AR (1) AR007079A1 (et)
AT (2) ATE350373T1 (et)
AU (1) AU710175B2 (et)
BG (1) BG64097B1 (et)
BR (1) BR9709065A (et)
CA (1) CA2253453C (et)
CZ (1) CZ295639B6 (et)
DE (2) DE69730962T2 (et)
EA (1) EA001360B1 (et)
EE (1) EE03563B1 (et)
ES (2) ES2230605T3 (et)
HK (2) HK1018457A1 (et)
HU (1) HUP9902993A3 (et)
ID (1) ID16889A (et)
IL (1) IL126968A0 (et)
MY (1) MY117852A (et)
NO (1) NO311027B1 (et)
NZ (1) NZ332309A (et)
PL (1) PL190721B1 (et)
SK (1) SK282919B6 (et)
TR (1) TR199802253T2 (et)
TW (1) TW593290B (et)
WO (1) WO1997043271A1 (et)
ZA (1) ZA974053B (et)

Families Citing this family (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT1293804B1 (it) 1997-08-01 1999-03-10 Recordati Chem Pharm Diarilalchilpiperazine attive sulle basse vie urinarie
US6281216B1 (en) * 1998-02-09 2001-08-28 Duphar International Research B.V. 2-aminoquinoline derivatives having d4-agonistic activity
EP0982030A3 (en) 1998-08-17 2000-05-10 Pfizer Products Inc. 2,7-substituted octahydro-pyrrolo 1,2-a]pyrazine derivatives as 5ht 1a ligands
AU6280199A (en) * 1998-09-30 2000-04-17 Neurogen Corporation 2-piperazino alkylamino benzoazole derivatives: dopamine receptor subtype specific ligands
US6284759B1 (en) * 1998-09-30 2001-09-04 Neurogen Corporation 2-piperazinoalkylaminobenzo-azole derivatives: dopamine receptor subtype specific ligands
US6107313A (en) * 1998-10-02 2000-08-22 Combichem, Inc. Dopamine receptor antagonists
WO2001000604A1 (en) * 1999-06-30 2001-01-04 Santen Pharmaceutical Co., Ltd. Brain sigma-1 receptor-binding ligand
DE60128211T2 (de) 2000-03-31 2008-01-10 Ortho-Mcneil Pharmaceutical, Inc. Phenyl-substituierte imidazopyridine
WO2001074810A2 (en) * 2000-03-31 2001-10-11 Ortho Mcneil Pharmaceutical, Inc. Method for using 2-aryloxyalkylaminobenzoxazoles and 2-aryloxyalkylaminobenzothiazoles as h3 antagonists
GB0203299D0 (en) * 2002-02-12 2002-03-27 Glaxo Group Ltd Novel compounds
BR0314059A (pt) * 2002-09-06 2005-07-05 Janssen Pharmaceutica Nv Compostos heterocìclicos
US8257680B1 (en) 2004-02-24 2012-09-04 The General Hospital Corporation Catalytic radiofluorination
US9017724B2 (en) 2004-02-24 2015-04-28 The General Hospital Corporation Catalytic radiofluorination
CA2552356C (en) * 2004-02-24 2013-11-19 The General Hospital Corporation Catalytic radiofluorination
FR2877005A1 (fr) * 2004-10-22 2006-04-28 Bioprojet Soc Civ Ile Nouveaux derives d'arylpiperazine
US7731940B2 (en) 2006-01-25 2010-06-08 The Regents Of The University Of California Compositions and methods related to serotonin 5-HT1A receptors
CA2718035C (en) 2008-03-21 2017-10-24 The General Hospital Corporation Inositol derivatives for the detection and treatment of alzheimer' s disease and related disorders
WO2018039512A1 (en) * 2016-08-26 2018-03-01 Bristol-Myers Squibb Company Inhibitors of indoleamine 2,3-dioxygenase and methods of their use
PT109740B (pt) * 2016-11-14 2020-07-30 Hovione Farmaciencia Sa Processo para a preparação de brometo de umeclidínio
KR20210091865A (ko) * 2020-01-14 2021-07-23 서울대학교산학협력단 혈관생성 저해 효과를 가지는 n-페닐벤조티아졸-2-아민 화합물 및 그를 포함하는 약제학적 조성물

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0187162B1 (en) * 1984-05-22 1989-11-02 Sumitomo Chemical Company, Limited Novel radioactive iodospiroperidol and process for its preparation
DE3874187T2 (de) * 1987-04-08 1993-04-08 Salutar Inc Nachweis fuer amyloidose und alzheimer'sche krankheit sowie reagens hierfuer.
US4929618A (en) * 1988-03-25 1990-05-29 Ube Industries, Ltd. Piperdine and piperazine derivatives, and antihistaminic pharmaceutical compositions containing the same
FR2656609B1 (fr) * 1989-12-28 1992-03-27 Synthelabo Derives de 2-aminopyrimidine-4-carboxamide, leur preparation et leur application en therapeutique.
US5731438A (en) * 1996-08-01 1998-03-24 Isis Pharmaceuticals, Inc. N-(aminoalkyl)-and/or N-(amidoalkyl)-dinitrogen heterocycles

Also Published As

Publication number Publication date
CZ295639B6 (cs) 2005-09-14
NO985227D0 (no) 1998-11-09
CN1218461A (zh) 1999-06-02
MY117852A (en) 2004-08-30
HUP9902993A2 (hu) 2000-05-28
BG64097B1 (bg) 2003-12-31
US6224849B1 (en) 2001-05-01
EP1325917A1 (en) 2003-07-09
HK1057044A1 (en) 2004-03-12
CA2253453C (en) 2007-01-16
ID16889A (id) 1997-11-20
PL329849A1 (en) 1999-04-12
NZ332309A (en) 1999-08-30
KR100330699B1 (ko) 2002-08-27
HUP9902993A3 (en) 2002-01-28
DE69737217T2 (de) 2007-11-08
IL126968A0 (en) 1999-09-22
TW593290B (en) 2004-06-21
EE03563B1 (et) 2001-12-17
EP0912533A1 (en) 1999-05-06
DE69730962D1 (de) 2004-11-04
NO311027B1 (no) 2001-10-01
EP0912533B1 (en) 2004-09-29
SK282919B6 (sk) 2003-01-09
PL190721B1 (pl) 2005-12-30
DE69730962T2 (de) 2006-03-30
EP1325917B1 (en) 2007-01-03
ES2279923T3 (es) 2007-09-01
KR20000005227A (ko) 2000-01-25
AU2956097A (en) 1997-12-05
CA2253453A1 (en) 1997-11-20
JP2000503667A (ja) 2000-03-28
EA199801000A1 (ru) 1999-04-29
DE69737217D1 (de) 2007-02-15
AU710175B2 (en) 1999-09-16
AR007079A1 (es) 1999-10-13
US6103725A (en) 2000-08-15
ATE277917T1 (de) 2004-10-15
TR199802253T2 (xx) 1999-02-22
EA001360B1 (ru) 2001-02-26
BG102819A (en) 1999-08-31
SK153298A3 (en) 1999-03-12
CZ355398A3 (cs) 1999-02-17
BR9709065A (pt) 1999-08-03
NO985227L (no) 1999-01-11
JP3237759B2 (ja) 2001-12-10
WO1997043271A1 (en) 1997-11-20
ATE350373T1 (de) 2007-01-15
ES2230605T3 (es) 2005-05-01
CN1074766C (zh) 2001-11-14
HK1018457A1 (en) 1999-12-24
ZA974053B (en) 1998-11-09

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Legal Events

Date Code Title Description
KB4A Valid patent at the end of a year

Effective date: 20021231

KB4A Valid patent at the end of a year

Effective date: 20031231

KB4A Valid patent at the end of a year

Effective date: 20041231

KB4A Valid patent at the end of a year

Effective date: 20051231

KB4A Valid patent at the end of a year

Effective date: 20061231

KB4A Valid patent at the end of a year

Effective date: 20071231

KB4A Valid patent at the end of a year

Effective date: 20081231

MM4A Lapsed by not paying the annual fees

Effective date: 20090502