EE200700052A - Antikeha he v?i mitme apo-lipoproteiin B fragmendi vastu - Google Patents

Antikeha he v?i mitme apo-lipoproteiin B fragmendi vastu

Info

Publication number
EE200700052A
EE200700052A EEP200700052A EEP200700052A EE200700052A EE 200700052 A EE200700052 A EE 200700052A EE P200700052 A EEP200700052 A EE P200700052A EE P200700052 A EEP200700052 A EE P200700052A EE 200700052 A EE200700052 A EE 200700052A
Authority
EE
Estonia
Prior art keywords
fragments
apo
lipoprotein
antibody against
against several
Prior art date
Application number
EEP200700052A
Other languages
English (en)
Estonian (et)
Inventor
Nilsson Jan
K. Shah Prediman
Original Assignee
Forskarpatent I Syd Ab
Cedars Sinai Medical Center
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from SE0101232A external-priority patent/SE0101232D0/xx
Application filed by Forskarpatent I Syd Ab, Cedars Sinai Medical Center filed Critical Forskarpatent I Syd Ab
Publication of EE200700052A publication Critical patent/EE200700052A/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/1703—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • A61K38/1709—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/06—Antianaemics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/775—Apolipopeptides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Immunology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • Cardiology (AREA)
  • Molecular Biology (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Biophysics (AREA)
  • Vascular Medicine (AREA)
  • Toxicology (AREA)
  • Diabetes (AREA)
  • Epidemiology (AREA)
  • Urology & Nephrology (AREA)
  • Marine Sciences & Fisheries (AREA)
  • Hematology (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicinal Preparation (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Medicines Containing Plant Substances (AREA)
EEP200700052A 2001-04-05 2002-04-05 Antikeha he v?i mitme apo-lipoproteiin B fragmendi vastu EE200700052A (et)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
SE0101232A SE0101232D0 (sv) 2001-04-05 2001-04-05 Peptide-based immunization therapy for treatment of atherosclerosis and development of peptide-based elisa for determination of immune responses against oxidized low density liprotein
SE0103754A SE0103754L (sv) 2001-04-05 2001-11-09 Peptider från apolipoprotein B, användning därav immunisering, diagnosmetod eller terapeutisk behandling av ischemiska kardiovaskulära sjukdomar, samt farmaceutisk komposition och vaccin innehållande sådan peptid
EEP200300487A EE200300487A (et) 2001-04-05 2002-04-05 Peptiid-põhine immunoteraapia ateroskleroosi raviks ja peptiid-põhise määramise arendamine immuunvastuste määramiseks oksüdeeritud madala tihedusega lipoproteiini vastu

Publications (1)

Publication Number Publication Date
EE200700052A true EE200700052A (et) 2008-08-15

Family

ID=26655437

Family Applications (2)

Application Number Title Priority Date Filing Date
EEP200700052A EE200700052A (et) 2001-04-05 2002-04-05 Antikeha he v?i mitme apo-lipoproteiin B fragmendi vastu
EEP200300487A EE200300487A (et) 2001-04-05 2002-04-05 Peptiid-põhine immunoteraapia ateroskleroosi raviks ja peptiid-põhise määramise arendamine immuunvastuste määramiseks oksüdeeritud madala tihedusega lipoproteiini vastu

Family Applications After (1)

Application Number Title Priority Date Filing Date
EEP200300487A EE200300487A (et) 2001-04-05 2002-04-05 Peptiid-põhine immunoteraapia ateroskleroosi raviks ja peptiid-põhise määramise arendamine immuunvastuste määramiseks oksüdeeritud madala tihedusega lipoproteiini vastu

Country Status (18)

Country Link
EP (42) EP2295463A1 (fr)
JP (6) JP2004529143A (fr)
CN (4) CN103122031B (fr)
AT (2) ATE510851T1 (fr)
AU (1) AU2002246484B8 (fr)
BR (1) BR0208685A (fr)
CA (3) CA2827167A1 (fr)
CY (1) CY1108817T1 (fr)
DE (1) DE60230029D1 (fr)
DK (3) DK2006301T3 (fr)
EE (2) EE200700052A (fr)
ES (2) ES2546293T3 (fr)
IL (4) IL158285A0 (fr)
PL (4) PL217858B1 (fr)
PT (1) PT1383526E (fr)
RU (1) RU2296582C2 (fr)
SE (1) SE0103754L (fr)
WO (1) WO2002080954A1 (fr)

Families Citing this family (34)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SE0103754L (sv) * 2001-04-05 2002-10-06 Forskarpatent I Syd Ab Peptider från apolipoprotein B, användning därav immunisering, diagnosmetod eller terapeutisk behandling av ischemiska kardiovaskulära sjukdomar, samt farmaceutisk komposition och vaccin innehållande sådan peptid
US20030105003A1 (en) 2001-04-05 2003-06-05 Jan Nilsson Peptide-based immunization therapy for treatment of atherosclerosis and development of peptide-based assay for determination of immune responses against oxidized low density lipoprotein
KR20040081418A (ko) 2001-09-28 2004-09-21 에스페리온 테라피유틱스 인코포레이티드 약물의 국소투여를 통한 재협착의 예방 및 치료
WO2004030607A2 (fr) * 2002-10-04 2004-04-15 Forskarpatent I Syd Ab Therapie d'immunisation passive a base peptidique pour le traitement de l'atherosclerose
SE0302312D0 (sv) * 2002-10-04 2003-08-27 Forskarpatent I Syd Ab Peptide-based passive immunization therapy for treatment of atherosclerosis
SE0302422D0 (sv) 2003-09-11 2003-09-11 Forskarpatent I Syd Ab Peptide-based immunization therapy for treatment of atherosclerosis
SE0400683D0 (sv) 2004-03-19 2004-03-19 Forskarpatent I Syd Ab Use of modified extracellular matrix proteins in diagnosis and treatment of a atherosclerosis
US8926958B2 (en) 2004-04-06 2015-01-06 Cedars-Sinai Medical Center Prevention and treatment of vascular disease with recombinant adeno-associated virus vectors encoding apolipoprotein A-I and apolipoprotein A-I milano
SI1797893T1 (sl) * 2004-04-15 2010-08-31 Athera Biotechnologies Ab Protitelesa proti fosforilholinskim konjugatom
EP1676602A1 (fr) 2005-01-04 2006-07-05 Institut National De La Sante Et De La Recherche Medicale (Inserm) Administration continue d'épitopes derivés de protéinse présentes dans la plaque atèrosclérotique pour le traitement de l'athérosclérose
GB0517878D0 (en) 2005-09-02 2005-10-12 Bioinvent Int Ab Immunotherapeutic treatment
CA2669863A1 (fr) * 2006-12-22 2008-07-03 Abbott Laboratories Panel de maladies auto-immunes cardiovasculaires et methodes d'utilisation correspondantes
WO2008104194A1 (fr) * 2007-02-28 2008-09-04 Bioinvent International Ab Lipoprotéines de basse densité oxyde et leurs anticorps pour le traitement de plaques d'athérosclérose
KR101473504B1 (ko) 2007-03-15 2014-12-16 노파르티스 아게 유기 화합물 및 그의 용도
JP6039879B2 (ja) * 2007-11-05 2016-12-07 ノルディック・ビオサイエンス・エー／エスＮｏｒｄｉｃ Ｂｉｏｓｃｉｅｎｃｅ Ａ／Ｓ Ｃｖｄリスク評価のための生化学マーカー
US20100041663A1 (en) 2008-07-18 2010-02-18 Novartis Ag Organic Compounds as Smo Inhibitors
KR101506314B1 (ko) * 2008-08-15 2015-04-06 후지쿠라 가세이 가부시키가이샤 동맥경화 진단용 폴리펩티드 마커, 및 상기 마커 등을 이용한 동맥 경화의 검출방법, 및 동맥경화 진단용 키트
AU2010319323B2 (en) * 2009-11-14 2015-01-15 Cardiovax, Llc Immunomodulatory methods and systems for treatment and/or prevention of atherosclerosis
US8506964B2 (en) * 2010-02-05 2013-08-13 Cardiovax, Llc Fusion proteins and related compositions, methods and systems for treatment and/or prevention of atherosclerosis
WO2012024309A2 (fr) 2010-08-18 2012-02-23 Cedars-Sinai Medical Center Inhibition de l'athérosclérose par le biais de la modulation du phénotype des monocytes-macrophages en utilisant le transfert du gène apo a-i milano
RU2013126626A (ru) 2010-11-12 2014-12-20 Седарс-Синаи Медикал Сентер Иммуномодулирующие способы и системы для лечения и/или предотвращения гипертензий
CA2817548A1 (fr) * 2010-11-12 2012-05-18 Cedars-Sinai Medical Center Compositions immunomodulatrices, methodes et systemes comportant des fragments immunogenes de apob100
CN103501806A (zh) * 2010-11-12 2014-01-08 赛达斯西奈医疗中心 用于治疗和/或预防动脉瘤的免疫调节方法和系统
CN103906532B (zh) 2011-08-09 2018-01-26 阿瑟拉生物技术公司 结合磷酰胆碱（pc）和/或pc结合物的抗体
ES2732838T3 (es) 2011-08-09 2019-11-26 Athera Biotechnologies Ab Nuevos anticuerpos frente a fosforilcolina
RU2495048C1 (ru) * 2012-04-18 2013-10-10 Андрей Валентинович Исаев Пептид, обладающий антиатеросклеротическим действием и композиция для профилактики и лечения атеросклероза сосудов
WO2014072916A1 (fr) * 2012-11-06 2014-05-15 Les Hopitaux Universitaires De Geneve Peptides mimétiques
CN103520713B (zh) * 2013-10-16 2015-10-28 西北农林科技大学 一种ApoB100酵母重组疫苗及其制备方法和应用
CN103860470A (zh) * 2014-03-05 2014-06-18 贵州中泰生物科技有限公司 一种口服高密度脂蛋白脂质体的制备方法
CN105315364B (zh) * 2014-06-17 2018-09-18 广州文瑞生物科技有限公司 胶原蛋白vi疫苗预防动脉粥样硬化
EP3297652A4 (fr) 2015-05-19 2019-06-05 La Jolla Institute for Allergy and Immunology Épitopes apob100 humains, méthodes et utilisations pour moduler des réponses inflammatoires et traiter des événements cardiovasculaires défavorables, la maladie cardiovasculaire et l'athérosclérose
US10858422B2 (en) 2016-05-31 2020-12-08 Abcentra, Llc Methods for treating systemic lupus erythematosus with an anti-apolipoprotein B antibody
CN108478817B (zh) * 2018-03-16 2020-10-27 北京大学 一种动脉粥样硬化检测试剂及其制备方法
US11690912B2 (en) 2018-05-29 2023-07-04 Abcentra, Llc Methods for treatment of rheumatoid arthritis and accelerated atherosclerosis with an anti-Apo B100 antibody

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WO2000002920A1 (fr) * 1998-07-13 2000-01-20 University Of Otago Inhibition de la formation de lipoproteines
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DE60045869D1 (de) * 1999-10-26 2011-06-01 Univ California Reagenzien und verfahren für diagnose, 'imaging' und behandlung von atherosklerotischen krankheiten
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SE0000855D0 (sv) * 2000-03-15 2000-03-15 Karolinska Innovations Ab Antigenic composition useful as a vaccine against atherosclerosis
GB0017641D0 (en) * 2000-07-18 2000-09-06 Medigene Oy Peptides and their use
EP1186299A1 (fr) * 2000-09-12 2002-03-13 Universitair Medisch Centrum Utrecht Diagnostic, prévention et/ou traitement d' athérosclérose, infections et perturbations du système immunitaire
WO2002048388A2 (fr) * 2000-10-25 2002-06-20 Vincent Agnello Procede d'inhibition de l'infection au virus de l'hepatite c (vhc) et autres virus de la famille des flaviridae, et a tout autre virus formant dans le sang un complexe avec une lipoproteine de basse densite ou tres basse densite, par empechement de l'entree virale dans une cellule
WO2002042426A2 (fr) * 2000-11-10 2002-05-30 University Of Utah Research Foundation Systeme de transporteur pour apport specifique de genes au niveau de la paroi arterielle
SE0103754L (sv) * 2001-04-05 2002-10-06 Forskarpatent I Syd Ab Peptider från apolipoprotein B, användning därav immunisering, diagnosmetod eller terapeutisk behandling av ischemiska kardiovaskulära sjukdomar, samt farmaceutisk komposition och vaccin innehållande sådan peptid
JP3944083B2 (ja) * 2001-05-15 2007-07-11 株式会社Ｊｉｍｒｏ 高密度リポ蛋白質反応性ペプチド
EP1469887A4 (fr) * 2001-07-20 2006-01-11 Eidgenoess Tech Hochschule Compositions et procedes pour l'utilisation d'agents bioactifs derives d'acides sulfates et sulfones

Also Published As

Publication number Publication date
CN101284874A (zh) 2008-10-15
DK2295464T3 (en) 2015-08-17
JP5270456B2 (ja) 2013-08-21
EP2289919A1 (fr) 2011-03-02
JP2011068654A (ja) 2011-04-07
EP2147929A3 (fr) 2010-04-14
CA2443223A1 (fr) 2002-10-17
EP2006301A1 (fr) 2008-12-24
CN101284874B (zh) 2012-10-03
IL158285A0 (en) 2004-05-12
EP2147930A2 (fr) 2010-01-27
AU2002246484B8 (en) 2007-06-14
CY1108817T1 (el) 2014-04-09
IL158285A (en) 2009-12-24
EP2295464B1 (fr) 2015-06-03
EP2295464A1 (fr) 2011-03-16
EP2147680A2 (fr) 2010-01-27
EP2289925A1 (fr) 2011-03-02
PL215401B1 (pl) 2013-12-31
DK1383526T3 (da) 2009-03-30
EP2147929A2 (fr) 2010-01-27
EP2289932A1 (fr) 2011-03-02
SE0103754D0 (sv) 2001-11-09
JP5300819B2 (ja) 2013-09-25
WO2002080954A1 (fr) 2002-10-17
CN1505525A (zh) 2004-06-16
AU2002246484B2 (en) 2007-04-19
EP2289935A1 (fr) 2011-03-02
EP2305708A1 (fr) 2011-04-06
EP2295457A1 (fr) 2011-03-16
EP2295463A1 (fr) 2011-03-16
PT1383526E (pt) 2009-02-27
CN101486766A (zh) 2009-07-22
EP2289924A1 (fr) 2011-03-02
EP2147928A3 (fr) 2010-04-14
ES2317999T3 (es) 2009-05-01
PL367301A1 (en) 2005-02-21
CA2606839C (fr) 2015-06-09
CN103122031B (zh) 2015-07-22
BR0208685A (pt) 2004-03-30
EP2289933A1 (fr) 2011-03-02
JP2004529143A (ja) 2004-09-24
EP2289926A1 (fr) 2011-03-02
JP2011063598A (ja) 2011-03-31
IL195356A0 (en) 2009-08-03
DE60230029D1 (de) 2009-01-08
EP2289929A1 (fr) 2011-03-02
EP2295460B1 (fr) 2015-06-03
EP1383526A1 (fr) 2004-01-28
ATE415423T1 (de) 2008-12-15
EP2006301B1 (fr) 2011-05-25
EP2305707A1 (fr) 2011-04-06
EP2289918A1 (fr) 2011-03-02
JP5613890B2 (ja) 2014-10-29
EP2289928A1 (fr) 2011-03-02
CA2443223C (fr) 2013-11-26
CN103122031A (zh) 2013-05-29
EP2147680A3 (fr) 2010-04-14
EP2289917A1 (fr) 2011-03-02
EP2147928A2 (fr) 2010-01-27
EP2305706A1 (fr) 2011-04-06
CA2827167A1 (fr) 2002-10-17
EP2289920A1 (fr) 2011-03-02
EP2289912A1 (fr) 2011-03-02
EP2147930A3 (fr) 2010-04-14
EP2289934A1 (fr) 2011-03-02
JP5300820B2 (ja) 2013-09-25
RU2003132443A (ru) 2005-02-27
CN1505525B (zh) 2012-11-07
EP2295461A1 (fr) 2011-03-16
EP2289914A1 (fr) 2011-03-02
JP2008169215A (ja) 2008-07-24
EP2289927A1 (fr) 2011-03-02
EP2295459A1 (fr) 2011-03-16
EP2289916A1 (fr) 2011-03-02
EP2295458A1 (fr) 2011-03-16
EP2289923A1 (fr) 2011-03-02
EP2289921A1 (fr) 2011-03-02
ES2546293T3 (es) 2015-09-22
EP2289931A1 (fr) 2011-03-02
ATE510851T1 (de) 2011-06-15
EP1918300A2 (fr) 2008-05-07
PL400308A1 (pl) 2012-12-17
CA2606839A1 (fr) 2002-10-17
IL188286A0 (en) 2008-03-20
EP1918300A3 (fr) 2009-06-17
EP2289922A1 (fr) 2011-03-02
EE200300487A (et) 2004-02-16
EP2289930A1 (fr) 2011-03-02
EP2295460A1 (fr) 2011-03-16
AU2002246484A1 (en) 2002-10-21
EP2289913A1 (fr) 2011-03-02
DK2006301T3 (da) 2011-09-12
EP1383526B1 (fr) 2008-11-26
EP2295462A1 (fr) 2011-03-16
EP2289934B1 (fr) 2013-11-13
EP2289915A1 (fr) 2011-03-02
SE0103754L (sv) 2002-10-06
JP2009191078A (ja) 2009-08-27
JP2013144687A (ja) 2013-07-25
RU2296582C2 (ru) 2007-04-10
PL217858B1 (pl) 2014-08-29

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