EE200200214A - Dipüridamooli või mopidamooli kasutamine sellise ravimi valmistamiseks, mis on ette nähtud fibriinsõltuvate mikrotsirkulatsiooni häirete ennetamiseksja raviks - Google Patents
Dipüridamooli või mopidamooli kasutamine sellise ravimi valmistamiseks, mis on ette nähtud fibriinsõltuvate mikrotsirkulatsiooni häirete ennetamiseksja raviksInfo
- Publication number
- EE200200214A EE200200214A EEP200200214A EEP200200214A EE200200214A EE 200200214 A EE200200214 A EE 200200214A EE P200200214 A EEP200200214 A EE P200200214A EE P200200214 A EEP200200214 A EE P200200214A EE 200200214 A EE200200214 A EE 200200214A
- Authority
- EE
- Estonia
- Prior art keywords
- mopidamol
- dipyridamole
- medicament
- prevention
- manufacture
- Prior art date
Links
Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
- A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
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- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
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- A—HUMAN NECESSITIES
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- A61K31/33—Heterocyclic compounds
- A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
- A61K31/365—Lactones
- A61K31/366—Lactones having six-membered rings, e.g. delta-lactones
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- A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
- A61K31/401—Proline; Derivatives thereof, e.g. captopril
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- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/47—Quinolines; Isoquinolines
- A61K31/4738—Quinolines; Isoquinolines ortho- or peri-condensed with heterocyclic ring systems
- A61K31/4743—Quinolines; Isoquinolines ortho- or peri-condensed with heterocyclic ring systems condensed with ring systems having sulfur as a ring hetero atom
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- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/715—Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
- A61K31/726—Glycosaminoglycans, i.e. mucopolysaccharides
- A61K31/727—Heparin; Heparan
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- A61P9/14—Vasoprotectives; Antihaemorrhoidals; Drugs for varicose therapy; Capillary stabilisers
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- General Health & Medical Sciences (AREA)
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- Public Health (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
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- General Chemical & Material Sciences (AREA)
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- Neurosurgery (AREA)
- Neurology (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Dermatology (AREA)
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- Immunology (AREA)
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- Vascular Medicine (AREA)
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- Emergency Medicine (AREA)
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- Ophthalmology & Optometry (AREA)
- Hospice & Palliative Care (AREA)
- Psychiatry (AREA)
- Endocrinology (AREA)
- Transplantation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP99121121A EP1093814A1 (en) | 1999-10-22 | 1999-10-22 | Use of dipyridamole or mopidamol in the manufacture of a medicament for the treatment and prevention of fibrin-dependent microcirculation disorders |
| PCT/EP2000/010123 WO2001030353A1 (en) | 1999-10-22 | 2000-10-14 | Use of dipyridamole or mopidamol in the manufacture of a medicament for the treatment and prevention of fibrin-dependent microcirculation disorders |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| EE200200214A true EE200200214A (et) | 2003-06-16 |
Family
ID=8239263
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| EEP200200214A EE200200214A (et) | 1999-10-22 | 2000-10-14 | Dipüridamooli või mopidamooli kasutamine sellise ravimi valmistamiseks, mis on ette nähtud fibriinsõltuvate mikrotsirkulatsiooni häirete ennetamiseksja raviks |
Country Status (27)
| Country | Link |
|---|---|
| US (2) | US20030149058A1 (et) |
| EP (2) | EP1093814A1 (et) |
| JP (1) | JP2003512431A (et) |
| KR (1) | KR20020040901A (et) |
| CN (2) | CN100411620C (et) |
| AR (1) | AR026197A1 (et) |
| AU (1) | AU784124B2 (et) |
| BG (1) | BG106609A (et) |
| BR (1) | BR0014946A (et) |
| CA (1) | CA2387486C (et) |
| CZ (1) | CZ20021487A3 (et) |
| EA (1) | EA200200448A1 (et) |
| EE (1) | EE200200214A (et) |
| HK (1) | HK1048597A1 (et) |
| HR (1) | HRP20020342A2 (et) |
| HU (1) | HUP0203249A3 (et) |
| IL (1) | IL148974A0 (et) |
| MX (1) | MXPA02003901A (et) |
| NO (1) | NO20021784D0 (et) |
| NZ (1) | NZ518525A (et) |
| PE (1) | PE20010747A1 (et) |
| PL (1) | PL354591A1 (et) |
| SK (1) | SK7112002A3 (et) |
| TR (1) | TR200201089T2 (et) |
| WO (1) | WO2001030353A1 (et) |
| YU (1) | YU30002A (et) |
| ZA (1) | ZA200203156B (et) |
Families Citing this family (22)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP1093814A1 (en) * | 1999-10-22 | 2001-04-25 | Boehringer Ingelheim Pharma KG | Use of dipyridamole or mopidamol in the manufacture of a medicament for the treatment and prevention of fibrin-dependent microcirculation disorders |
| US7064130B2 (en) * | 2001-04-20 | 2006-06-20 | Boehringer Ingelheim Pharma Gmbh & Co. Kg | Use of radical-scavenging compounds for treatment and prevention of NO-dependent microcirculation disorders |
| DE10119680A1 (de) * | 2001-04-20 | 2002-11-14 | Boehringer Ingelheim Pharma | Verwendung von Radikalfänger-Verbindungen zur Behandlung und Verhinderung von no-abhängigen Störungen der Mikrozirkulation |
| MXPA04003266A (es) * | 2001-10-05 | 2004-07-08 | Combinatorx Inc | Combinaciones para el tratamiento de desodrdenes inmuno-inflamatorios. |
| MY131170A (en) * | 2002-03-28 | 2007-07-31 | Nissan Chemical Ind Ltd | Therapeutic agent for glomerular disease |
| DE10335027A1 (de) * | 2003-07-31 | 2005-02-17 | Boehringer Ingelheim Pharma Gmbh & Co. Kg | Verwendung von Angiotensin II Rezeptor Antagonisten |
| JP2006516593A (ja) * | 2003-02-07 | 2006-07-06 | ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング | Mmp−9依存性疾患の治療及び予防のためのジピリダモール又はモピダモールの使用 |
| DE10306179A1 (de) * | 2003-02-13 | 2004-08-26 | Boehringer Ingelheim Pharma Gmbh & Co. Kg | Verwendung von Dipyridamol in Kombination mit Acetylsalicylsäure und einem Angiotensin II-Antagonisten zur Schlaganfall-Prophylaxe |
| RU2005136383A (ru) * | 2003-04-24 | 2007-06-10 | БЕРИНГЕР ИНГЕЛЬХАЙМ ИНТЕРНАЦИОНАЛЬ ГмбХ (DE) | Применение дипиридамола или мопидамола для лечения и предупреждения тромбоэмболических заболеваний и нарушений, вызываемыхизбыточным образованием и/или повышенным уровнем экспрессии тромбиновых рецепторов |
| JP2005060359A (ja) * | 2003-08-13 | 2005-03-10 | Boehringer Ingelheim Pharma Gmbh & Co Kg | 血管系病態の治療及び予防のためのジピリダモール、アセチルサリチル酸及びアンギオテンシンii拮抗薬の使用 |
| TW200517114A (en) * | 2003-10-15 | 2005-06-01 | Combinatorx Inc | Methods and reagents for the treatment of immunoinflammatory disorders |
| CN101068570A (zh) | 2004-05-13 | 2007-11-07 | 贝林格尔·英格海姆国际有限公司 | 双嘧达莫治疗血小板抑制剂的抗药性的用途 |
| JP4880591B2 (ja) | 2004-06-04 | 2012-02-22 | テバ ファーマシューティカル インダストリーズ リミティド | イルベサルタンを含む医薬組成物 |
| CN101365453A (zh) * | 2006-02-09 | 2009-02-11 | 特瓦制药工业有限公司 | 双嘧达莫缓释制剂及其制备方法 |
| US20100062066A1 (en) * | 2006-11-14 | 2010-03-11 | Acusphere, Inc | Formulations of Tetrahydropyridine Antiplatelet Agents for Parenteral or Oral Administration |
| CA2910766C (en) * | 2013-04-30 | 2020-12-15 | Otitopic Inc. | Dry powder formulations and methods of use |
| TW201503900A (zh) * | 2013-07-29 | 2015-02-01 | ren-zheng Lin | 增強治療急性中風之抗血小板藥物之遞送方法及其組合物 |
| JP6925272B2 (ja) * | 2015-01-28 | 2021-08-25 | リアルイン ライフ サイエンス リミテッド | PPARγ発現および核転座を促進する化合物およびそれの治療的使用 |
| KR101736832B1 (ko) | 2017-02-28 | 2017-05-17 | 초당약품공업 주식회사 | 디피리다몰을 유효 성분으로 함유하는 신장 질환 치료용 의약 조성물 |
| CN114432451B (zh) * | 2018-12-21 | 2024-02-09 | 广州市妇女儿童医疗中心 | 胃肠道疾病的免疫机制及治疗药物 |
| CN111346228B (zh) * | 2018-12-21 | 2022-01-14 | 广州市妇女儿童医疗中心 | 胃肠道疾病的免疫机制及治疗药物 |
| CN115770219B (zh) * | 2023-02-13 | 2023-06-02 | 智泽童康(广州)生物科技有限公司 | 一种双嘧达莫干混悬剂及其制备方法和应用 |
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| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3031450A (en) * | 1959-04-30 | 1962-04-24 | Thomae Gmbh Dr K | Substituted pyrimido-[5, 4-d]-pyrimidines |
| DE2735830A1 (de) * | 1977-08-09 | 1979-03-01 | Thomae Gmbh Dr K | Antithrombotische arzneimittelkombination und verfahren zu ihrer herstellung |
| DE3000979A1 (de) * | 1980-01-12 | 1981-07-23 | Dr. Karl Thomae Gmbh, 7950 Biberach | Neue dipyridamol-retardformen und verfahren zu ihrer herstellung |
| DE3124090A1 (de) * | 1981-06-19 | 1983-01-05 | Dr. Karl Thomae Gmbh, 7950 Biberach | Neue orale dipyridamolformen |
| DE3237575A1 (de) * | 1982-10-09 | 1984-04-12 | Dr. Karl Thomae Gmbh, 7950 Biberach | Neue orale mopidamolformen |
| JPS6153271A (ja) * | 1984-08-24 | 1986-03-17 | Kaken Pharmaceut Co Ltd | ローダニン誘導体 |
| ATE50497T1 (de) * | 1984-07-21 | 1990-03-15 | Hoechst Ag | Kombinationspraeparat aus pyrimido-pyrimidinen und o-acetylsalicylsaeure bzw. deren pharmakologisch vertraeglichen salzen und dessen verwendung. |
| DE3627423A1 (de) * | 1986-08-13 | 1988-02-18 | Thomae Gmbh Dr K | Arzneimittel enthaltend dipyridamol oder mopidamol und o-acetylsalicylsaeure bzw. deren physiologisch vertraegliche salze, verfahren zu ihrer herstellung und ihre verwendung zur bekaempfung der thrombusbildung |
| US5242921A (en) * | 1988-04-27 | 1993-09-07 | Yale University | Compositions and methods for treating cutaneous hyperproliferative disorders |
| SU1685450A1 (ru) * | 1989-03-10 | 1991-10-23 | Московский медицинский стоматологический институт им.Н.А.Семашко | Способ лечени скаленус-синдрома при шейном остеохондрозе |
| IT1239064B (it) * | 1990-05-14 | 1993-09-20 | Fidia Spa | Uso terapeutico del dipiridamolo |
| US5639482A (en) * | 1993-11-10 | 1997-06-17 | Crary; Ely J. | Composition for control and prevention of diabetic retinopathy |
| CN1111985A (zh) * | 1994-05-06 | 1995-11-22 | 王志刚 | 阿司匹林与潘生丁复方多层片的制备方法 |
| US5498613A (en) * | 1994-06-07 | 1996-03-12 | The University Of Southern California | Dipyridamole and analogs thereof in preventing adhesion formation |
| US5968983A (en) * | 1994-10-05 | 1999-10-19 | Nitrosystems, Inc | Method and formulation for treating vascular disease |
| US5620409A (en) * | 1995-09-15 | 1997-04-15 | The Research Foundation Of State University Of New York | Method for inhibiting clot formation |
| CN1152436A (zh) * | 1995-12-22 | 1997-06-25 | 王介明 | 一种治疗缺血性脑血管病和脑血栓的康复液及其制法 |
| WO1998055142A1 (en) * | 1997-06-05 | 1998-12-10 | Eli Lilly And Company | Methods for treating thrombotic disorders |
| CN1108798C (zh) * | 1999-01-26 | 2003-05-21 | 广东药学院 | 一种治疗、预防血栓形成及中风的复方制剂及其制备方法 |
| CA2378257A1 (en) * | 1999-08-10 | 2001-02-15 | William E. Sponsel | Method for increasing optic nerve, choroidal and retinal blood flow to facilitate the preservation of sight |
| EP1093814A1 (en) * | 1999-10-22 | 2001-04-25 | Boehringer Ingelheim Pharma KG | Use of dipyridamole or mopidamol in the manufacture of a medicament for the treatment and prevention of fibrin-dependent microcirculation disorders |
| DE10011482B4 (de) * | 2000-03-09 | 2004-06-09 | Fresenius Hemocare Gmbh | Verfahren zum Herstellen eines Adsorbens zum Absenken der Konzentration von Fibrinogen und/oder Fibrin, Adsorbens und Verwendung des Adsorbens zur Herstellung eines Adsorbers |
| US6979462B1 (en) * | 2000-10-03 | 2005-12-27 | Mutual Pharmaceutical Co., Inc. | Stabilization of solid drug formulations |
| US7064130B2 (en) * | 2001-04-20 | 2006-06-20 | Boehringer Ingelheim Pharma Gmbh & Co. Kg | Use of radical-scavenging compounds for treatment and prevention of NO-dependent microcirculation disorders |
| US20020187187A1 (en) * | 2001-04-21 | 2002-12-12 | Toshimitsu Ohki | Fast disintegrating meloxicam tablet |
| US7064103B2 (en) * | 2002-01-04 | 2006-06-20 | Becton, Dickinson And Company | Binding protein as biosensors |
| US20030180282A1 (en) * | 2002-03-25 | 2003-09-25 | Victor Serebruany | Method of treatment of thrombotic events |
| JP2006516593A (ja) * | 2003-02-07 | 2006-07-06 | ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング | Mmp−9依存性疾患の治療及び予防のためのジピリダモール又はモピダモールの使用 |
| RU2005136383A (ru) * | 2003-04-24 | 2007-06-10 | БЕРИНГЕР ИНГЕЛЬХАЙМ ИНТЕРНАЦИОНАЛЬ ГмбХ (DE) | Применение дипиридамола или мопидамола для лечения и предупреждения тромбоэмболических заболеваний и нарушений, вызываемыхизбыточным образованием и/или повышенным уровнем экспрессии тромбиновых рецепторов |
-
1999
- 1999-10-22 EP EP99121121A patent/EP1093814A1/en not_active Withdrawn
-
2000
- 2000-10-14 SK SK711-2002A patent/SK7112002A3/sk not_active Application Discontinuation
- 2000-10-14 CA CA002387486A patent/CA2387486C/en not_active Expired - Fee Related
- 2000-10-14 AU AU12721/01A patent/AU784124B2/en not_active Ceased
- 2000-10-14 EA EA200200448A patent/EA200200448A1/ru unknown
- 2000-10-14 JP JP2001532773A patent/JP2003512431A/ja active Pending
- 2000-10-14 PL PL00354591A patent/PL354591A1/xx not_active Application Discontinuation
- 2000-10-14 HU HU0203249A patent/HUP0203249A3/hu unknown
- 2000-10-14 MX MXPA02003901A patent/MXPA02003901A/es unknown
- 2000-10-14 HK HK03100835.6A patent/HK1048597A1/zh unknown
- 2000-10-14 NZ NZ518525A patent/NZ518525A/en unknown
- 2000-10-14 BR BR0014946-2A patent/BR0014946A/pt not_active IP Right Cessation
- 2000-10-14 YU YU30002A patent/YU30002A/sh unknown
- 2000-10-14 HR HR20020342A patent/HRP20020342A2/hr not_active Application Discontinuation
- 2000-10-14 CZ CZ20021487A patent/CZ20021487A3/cs unknown
- 2000-10-14 WO PCT/EP2000/010123 patent/WO2001030353A1/en not_active Ceased
- 2000-10-14 TR TR2002/01089T patent/TR200201089T2/xx unknown
- 2000-10-14 EE EEP200200214A patent/EE200200214A/et unknown
- 2000-10-14 CN CNB008146756A patent/CN100411620C/zh not_active Expired - Fee Related
- 2000-10-14 EP EP00974393A patent/EP1225900A1/en not_active Withdrawn
- 2000-10-14 CN CNA2005101362547A patent/CN1823780A/zh active Pending
- 2000-10-14 IL IL14897400A patent/IL148974A0/xx unknown
- 2000-10-14 KR KR1020027005042A patent/KR20020040901A/ko not_active Ceased
- 2000-10-20 AR ARP000105541A patent/AR026197A1/es unknown
- 2000-10-20 PE PE2000001127A patent/PE20010747A1/es not_active Application Discontinuation
-
2002
- 2002-04-12 BG BG106609A patent/BG106609A/bg unknown
- 2002-04-16 NO NO20021784A patent/NO20021784D0/no not_active Application Discontinuation
- 2002-04-22 ZA ZA200203156A patent/ZA200203156B/xx unknown
-
2003
- 2003-02-27 US US10/376,072 patent/US20030149058A1/en not_active Abandoned
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2007
- 2007-12-18 US US11/958,504 patent/US20080113934A1/en not_active Abandoned
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