NO20021784L - Anvendelse av dipyridamol eller mopidamol for fremstilling av et medikament for behandling og forebygging av fibrin-avhengigmikrosirkulasjonsforstyrrelser - Google Patents
Anvendelse av dipyridamol eller mopidamol for fremstilling av et medikament for behandling og forebygging av fibrin-avhengigmikrosirkulasjonsforstyrrelserInfo
- Publication number
- NO20021784L NO20021784L NO20021784A NO20021784A NO20021784L NO 20021784 L NO20021784 L NO 20021784L NO 20021784 A NO20021784 A NO 20021784A NO 20021784 A NO20021784 A NO 20021784A NO 20021784 L NO20021784 L NO 20021784L
- Authority
- NO
- Norway
- Prior art keywords
- mopidamole
- dipyridamole
- fibrin
- medicament
- prevention
- Prior art date
Links
- 102000009123 Fibrin Human genes 0.000 title 1
- 108010073385 Fibrin Proteins 0.000 title 1
- BWGVNKXGVNDBDI-UHFFFAOYSA-N Fibrin monomer Chemical compound CNC(=O)CNC(=O)CN BWGVNKXGVNDBDI-UHFFFAOYSA-N 0.000 title 1
- 230000001419 dependent effect Effects 0.000 title 1
- IZEKFCXSFNUWAM-UHFFFAOYSA-N dipyridamole Chemical compound C=12N=C(N(CCO)CCO)N=C(N3CCCCC3)C2=NC(N(CCO)CCO)=NC=1N1CCCCC1 IZEKFCXSFNUWAM-UHFFFAOYSA-N 0.000 title 1
- 229960002768 dipyridamole Drugs 0.000 title 1
- 239000003814 drug Substances 0.000 title 1
- 229950003499 fibrin Drugs 0.000 title 1
- 238000004519 manufacturing process Methods 0.000 title 1
- 230000002265 prevention Effects 0.000 title 1
Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
-
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- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
- A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
-
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- A61K31/33—Heterocyclic compounds
- A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
- A61K31/365—Lactones
- A61K31/366—Lactones having six-membered rings, e.g. delta-lactones
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- A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
- A61K31/401—Proline; Derivatives thereof, e.g. captopril
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- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/47—Quinolines; Isoquinolines
- A61K31/4738—Quinolines; Isoquinolines ortho- or peri-condensed with heterocyclic ring systems
- A61K31/4743—Quinolines; Isoquinolines ortho- or peri-condensed with heterocyclic ring systems condensed with ring systems having sulfur as a ring hetero atom
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- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/715—Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
- A61K31/726—Glycosaminoglycans, i.e. mucopolysaccharides
- A61K31/727—Heparin; Heparan
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Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Epidemiology (AREA)
- Diabetes (AREA)
- Heart & Thoracic Surgery (AREA)
- Cardiology (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Dermatology (AREA)
- Hematology (AREA)
- Urology & Nephrology (AREA)
- Immunology (AREA)
- Obesity (AREA)
- Molecular Biology (AREA)
- Vascular Medicine (AREA)
- Ophthalmology & Optometry (AREA)
- Psychiatry (AREA)
- Emergency Medicine (AREA)
- Endocrinology (AREA)
- Pain & Pain Management (AREA)
- Rheumatology (AREA)
- Hospice & Palliative Care (AREA)
- Gastroenterology & Hepatology (AREA)
- Toxicology (AREA)
- Transplantation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
EP99121121A EP1093814A1 (en) | 1999-10-22 | 1999-10-22 | Use of dipyridamole or mopidamol in the manufacture of a medicament for the treatment and prevention of fibrin-dependent microcirculation disorders |
PCT/EP2000/010123 WO2001030353A1 (en) | 1999-10-22 | 2000-10-14 | Use of dipyridamole or mopidamol in the manufacture of a medicament for the treatment and prevention of fibrin-dependent microcirculation disorders |
Publications (2)
Publication Number | Publication Date |
---|---|
NO20021784D0 NO20021784D0 (no) | 2002-04-16 |
NO20021784L true NO20021784L (no) | 2002-04-16 |
Family
ID=8239263
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
NO20021784A NO20021784L (no) | 1999-10-22 | 2002-04-16 | Anvendelse av dipyridamol eller mopidamol for fremstilling av et medikament for behandling og forebygging av fibrin-avhengigmikrosirkulasjonsforstyrrelser |
Country Status (27)
Country | Link |
---|---|
US (2) | US20030149058A1 (no) |
EP (2) | EP1093814A1 (no) |
JP (1) | JP2003512431A (no) |
KR (1) | KR20020040901A (no) |
CN (2) | CN1823780A (no) |
AR (1) | AR026197A1 (no) |
AU (1) | AU784124B2 (no) |
BG (1) | BG106609A (no) |
BR (1) | BR0014946A (no) |
CA (1) | CA2387486C (no) |
CZ (1) | CZ20021487A3 (no) |
EA (1) | EA200200448A1 (no) |
EE (1) | EE200200214A (no) |
HK (1) | HK1048597A1 (no) |
HR (1) | HRP20020342A2 (no) |
HU (1) | HUP0203249A3 (no) |
IL (1) | IL148974A0 (no) |
MX (1) | MXPA02003901A (no) |
NO (1) | NO20021784L (no) |
NZ (1) | NZ518525A (no) |
PE (1) | PE20010747A1 (no) |
PL (1) | PL354591A1 (no) |
SK (1) | SK7112002A3 (no) |
TR (1) | TR200201089T2 (no) |
WO (1) | WO2001030353A1 (no) |
YU (1) | YU30002A (no) |
ZA (1) | ZA200203156B (no) |
Families Citing this family (22)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP1093814A1 (en) * | 1999-10-22 | 2001-04-25 | Boehringer Ingelheim Pharma KG | Use of dipyridamole or mopidamol in the manufacture of a medicament for the treatment and prevention of fibrin-dependent microcirculation disorders |
US7064130B2 (en) * | 2001-04-20 | 2006-06-20 | Boehringer Ingelheim Pharma Gmbh & Co. Kg | Use of radical-scavenging compounds for treatment and prevention of NO-dependent microcirculation disorders |
DE10119680A1 (de) * | 2001-04-20 | 2002-11-14 | Boehringer Ingelheim Pharma | Verwendung von Radikalfänger-Verbindungen zur Behandlung und Verhinderung von no-abhängigen Störungen der Mikrozirkulation |
US7253155B2 (en) | 2001-10-05 | 2007-08-07 | Combinatorx, Inc. | Combinations for the treatment of immunoinflammatory disorders |
MY131170A (en) | 2002-03-28 | 2007-07-31 | Nissan Chemical Ind Ltd | Therapeutic agent for glomerular disease |
DE10335027A1 (de) * | 2003-07-31 | 2005-02-17 | Boehringer Ingelheim Pharma Gmbh & Co. Kg | Verwendung von Angiotensin II Rezeptor Antagonisten |
WO2004069254A2 (en) * | 2003-02-07 | 2004-08-19 | Boehringer Ingelheim International Gmbh | Use of dipyridamole or mopidamole for treatment and prevention of mmp-9-dependent disorders |
DE10306179A1 (de) * | 2003-02-13 | 2004-08-26 | Boehringer Ingelheim Pharma Gmbh & Co. Kg | Verwendung von Dipyridamol in Kombination mit Acetylsalicylsäure und einem Angiotensin II-Antagonisten zur Schlaganfall-Prophylaxe |
EP1622621A2 (en) * | 2003-04-24 | 2006-02-08 | Boehringer Ingelheim International GmbH | Use of dipyridamole or mopidamole for treatment and prevention of thrombo-embolic diseases and disorders caused by excessive formation of thrombin and/or by elevated expression of thrombin receptors |
JP2005060359A (ja) * | 2003-08-13 | 2005-03-10 | Boehringer Ingelheim Pharma Gmbh & Co Kg | 血管系病態の治療及び予防のためのジピリダモール、アセチルサリチル酸及びアンギオテンシンii拮抗薬の使用 |
TW200517114A (en) * | 2003-10-15 | 2005-06-01 | Combinatorx Inc | Methods and reagents for the treatment of immunoinflammatory disorders |
KR20070026577A (ko) | 2004-05-13 | 2007-03-08 | 베링거 인겔하임 인터내셔날 게엠베하 | 혈소판 억제제 저항성 치료를 위한 디피리다몰의 용도 |
ATE493973T1 (de) | 2004-06-04 | 2011-01-15 | Teva Pharma | Irbesartan enthaltende pharmazeutische zusammensetzung |
EP1820506B1 (en) * | 2006-02-09 | 2008-03-26 | Teva Pharmaceutical Industries Ltd. | Dipyridamole extended-release formulations and process for preparing same |
WO2008060934A2 (en) * | 2006-11-14 | 2008-05-22 | Acusphere, Inc. | Formulations of tetrahydropyridine antiplatelet agents for parenteral or oral administration |
EP3607941A1 (en) * | 2013-04-30 | 2020-02-12 | Otitopic Inc. | Dry powder formulations and methods of use |
TW201503900A (zh) * | 2013-07-29 | 2015-02-01 | ren-zheng Lin | 增強治療急性中風之抗血小板藥物之遞送方法及其組合物 |
CN115282152A (zh) * | 2015-01-28 | 2022-11-04 | 瑞采生技有限公司 | 用于增强PPARγ表现及核转位之化合物及其医疗用途 |
KR101736832B1 (ko) | 2017-02-28 | 2017-05-17 | 초당약품공업 주식회사 | 디피리다몰을 유효 성분으로 함유하는 신장 질환 치료용 의약 조성물 |
CN114432451B (zh) * | 2018-12-21 | 2024-02-09 | 广州市妇女儿童医疗中心 | 胃肠道疾病的免疫机制及治疗药物 |
CN111346228B (zh) * | 2018-12-21 | 2022-01-14 | 广州市妇女儿童医疗中心 | 胃肠道疾病的免疫机制及治疗药物 |
CN118477044A (zh) * | 2023-02-13 | 2024-08-13 | 智泽童康(广州)生物科技有限公司 | 一种双嘧达莫的矫味组合物、干混悬剂及其应用 |
Family Cites Families (29)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3031450A (en) * | 1959-04-30 | 1962-04-24 | Thomae Gmbh Dr K | Substituted pyrimido-[5, 4-d]-pyrimidines |
DE2735830A1 (de) * | 1977-08-09 | 1979-03-01 | Thomae Gmbh Dr K | Antithrombotische arzneimittelkombination und verfahren zu ihrer herstellung |
DE3000979A1 (de) * | 1980-01-12 | 1981-07-23 | Dr. Karl Thomae Gmbh, 7950 Biberach | Neue dipyridamol-retardformen und verfahren zu ihrer herstellung |
DE3124090A1 (de) * | 1981-06-19 | 1983-01-05 | Dr. Karl Thomae Gmbh, 7950 Biberach | Neue orale dipyridamolformen |
DE3237575A1 (de) * | 1982-10-09 | 1984-04-12 | Dr. Karl Thomae Gmbh, 7950 Biberach | Neue orale mopidamolformen |
JPS6153271A (ja) * | 1984-08-24 | 1986-03-17 | Kaken Pharmaceut Co Ltd | ローダニン誘導体 |
ATE50497T1 (de) * | 1984-07-21 | 1990-03-15 | Hoechst Ag | Kombinationspraeparat aus pyrimido-pyrimidinen und o-acetylsalicylsaeure bzw. deren pharmakologisch vertraeglichen salzen und dessen verwendung. |
DE3627423A1 (de) * | 1986-08-13 | 1988-02-18 | Thomae Gmbh Dr K | Arzneimittel enthaltend dipyridamol oder mopidamol und o-acetylsalicylsaeure bzw. deren physiologisch vertraegliche salze, verfahren zu ihrer herstellung und ihre verwendung zur bekaempfung der thrombusbildung |
US5242921A (en) * | 1988-04-27 | 1993-09-07 | Yale University | Compositions and methods for treating cutaneous hyperproliferative disorders |
SU1685450A1 (ru) * | 1989-03-10 | 1991-10-23 | Московский медицинский стоматологический институт им.Н.А.Семашко | Способ лечени скаленус-синдрома при шейном остеохондрозе |
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CN1111985A (zh) * | 1994-05-06 | 1995-11-22 | 王志刚 | 阿司匹林与潘生丁复方多层片的制备方法 |
US5498613A (en) * | 1994-06-07 | 1996-03-12 | The University Of Southern California | Dipyridamole and analogs thereof in preventing adhesion formation |
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AU779991B2 (en) * | 1999-08-10 | 2005-02-24 | Board Of Regents, The University Of Texas System | Method for increasing optic nerve, choroidal and retinal blood flow to facilitate the preservation of sight |
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DE10011482B4 (de) * | 2000-03-09 | 2004-06-09 | Fresenius Hemocare Gmbh | Verfahren zum Herstellen eines Adsorbens zum Absenken der Konzentration von Fibrinogen und/oder Fibrin, Adsorbens und Verwendung des Adsorbens zur Herstellung eines Adsorbers |
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WO2004069254A2 (en) * | 2003-02-07 | 2004-08-19 | Boehringer Ingelheim International Gmbh | Use of dipyridamole or mopidamole for treatment and prevention of mmp-9-dependent disorders |
EP1622621A2 (en) * | 2003-04-24 | 2006-02-08 | Boehringer Ingelheim International GmbH | Use of dipyridamole or mopidamole for treatment and prevention of thrombo-embolic diseases and disorders caused by excessive formation of thrombin and/or by elevated expression of thrombin receptors |
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1999
- 1999-10-22 EP EP99121121A patent/EP1093814A1/en not_active Withdrawn
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2000
- 2000-10-14 CZ CZ20021487A patent/CZ20021487A3/cs unknown
- 2000-10-14 JP JP2001532773A patent/JP2003512431A/ja active Pending
- 2000-10-14 BR BR0014946-2A patent/BR0014946A/pt not_active Expired - Fee Related
- 2000-10-14 PL PL00354591A patent/PL354591A1/xx not_active Application Discontinuation
- 2000-10-14 KR KR1020027005042A patent/KR20020040901A/ko not_active Application Discontinuation
- 2000-10-14 EP EP00974393A patent/EP1225900A1/en not_active Withdrawn
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- 2000-10-14 HU HU0203249A patent/HUP0203249A3/hu unknown
- 2000-10-14 CN CNA2005101362547A patent/CN1823780A/zh active Pending
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2002
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2003
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2007
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