PE20010747A1 - Uso de dipiridamol o mopidamol para el tratamiento y prevencion de trastornos de la microcirculacion dependientes de fibrina - Google Patents

Uso de dipiridamol o mopidamol para el tratamiento y prevencion de trastornos de la microcirculacion dependientes de fibrina

Info

Publication number
PE20010747A1
PE20010747A1 PE2000001127A PE0011272000A PE20010747A1 PE 20010747 A1 PE20010747 A1 PE 20010747A1 PE 2000001127 A PE2000001127 A PE 2000001127A PE 0011272000 A PE0011272000 A PE 0011272000A PE 20010747 A1 PE20010747 A1 PE 20010747A1
Authority
PE
Peru
Prior art keywords
disorders
dipyridamol
mopidamol
fibrin
treatment
Prior art date
Application number
PE2000001127A
Other languages
English (en)
Inventor
Wolfgang Eisert
Original Assignee
Boehringer Ingelheim Pharma
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Boehringer Ingelheim Pharma filed Critical Boehringer Ingelheim Pharma
Publication of PE20010747A1 publication Critical patent/PE20010747A1/es

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    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
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    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61K31/33—Heterocyclic compounds
    • A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/365—Lactones
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    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • A61K31/401—Proline; Derivatives thereof, e.g. captopril
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    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47—Quinolines; Isoquinolines
    • A61K31/4738—Quinolines; Isoquinolines ortho- or peri-condensed with heterocyclic ring systems
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  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

SE REFIERE AL USO DE PIRIMIDO-PIRIMIDINA TAL COMO DIPIRIDAMOL, MOPIDAMOL EN COMBINACION CON UNO O MAS AGENTES ANTITROMBOTICOS, UN INHIBIDOR DE ECA, ANTAGONISTAS DE ANGIOTENSINA II, ANTAGONISTAS DE CALCIO; PARA LA FABRICACION DE UNA PREPARACION FARMACEUTICA PARA EL TRATAMIENTO DE TRASTORNOS DE MICROCIRCULACION DEPENDIENTES DE FIBRINA O TRASTORNOS EN LOS CUALES ESTAN IMPLICADOS TALES TRASTORNOS DE LA MICROCIRCULACION COMO ANGIOPATIA DIABETICA, REACCIONES INFLAMATORIAS, ENFERMEDAD DE CROHN, ENFERMEDADES AUTOINMUNES, HEPATITIS, CIRROSIS, ESCLEROSIS MULTIPLE, ENFERMEDAD DE RAYNAUD, ENFERMEDADES TUMORALES, NEFROESCLEROSIS, SINDROME HEMOLITICO UREMICO, HIPERTENSION ARTERIAL, DEMENCIA VASCULAR, ENFERMEDAD DE ALZHEIMER, DEMENCIA VASCULAR, TROMBOSIS CENTRAL VENOSA DEL OJO, ENFERMEDADES CARDIACAS ISQUEMICAS O CORONARIAS
PE2000001127A 1999-10-22 2000-10-20 Uso de dipiridamol o mopidamol para el tratamiento y prevencion de trastornos de la microcirculacion dependientes de fibrina PE20010747A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
EP99121121A EP1093814A1 (en) 1999-10-22 1999-10-22 Use of dipyridamole or mopidamol in the manufacture of a medicament for the treatment and prevention of fibrin-dependent microcirculation disorders

Publications (1)

Publication Number Publication Date
PE20010747A1 true PE20010747A1 (es) 2001-07-24

Family

ID=8239263

Family Applications (1)

Application Number Title Priority Date Filing Date
PE2000001127A PE20010747A1 (es) 1999-10-22 2000-10-20 Uso de dipiridamol o mopidamol para el tratamiento y prevencion de trastornos de la microcirculacion dependientes de fibrina

Country Status (27)

Country Link
US (2) US20030149058A1 (es)
EP (2) EP1093814A1 (es)
JP (1) JP2003512431A (es)
KR (1) KR20020040901A (es)
CN (2) CN1823780A (es)
AR (1) AR026197A1 (es)
AU (1) AU784124B2 (es)
BG (1) BG106609A (es)
BR (1) BR0014946A (es)
CA (1) CA2387486C (es)
CZ (1) CZ20021487A3 (es)
EA (1) EA200200448A1 (es)
EE (1) EE200200214A (es)
HK (1) HK1048597A1 (es)
HR (1) HRP20020342A2 (es)
HU (1) HUP0203249A3 (es)
IL (1) IL148974A0 (es)
MX (1) MXPA02003901A (es)
NO (1) NO20021784L (es)
NZ (1) NZ518525A (es)
PE (1) PE20010747A1 (es)
PL (1) PL354591A1 (es)
SK (1) SK7112002A3 (es)
TR (1) TR200201089T2 (es)
WO (1) WO2001030353A1 (es)
YU (1) YU30002A (es)
ZA (1) ZA200203156B (es)

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EP1093814A1 (en) * 1999-10-22 2001-04-25 Boehringer Ingelheim Pharma KG Use of dipyridamole or mopidamol in the manufacture of a medicament for the treatment and prevention of fibrin-dependent microcirculation disorders
US7064130B2 (en) * 2001-04-20 2006-06-20 Boehringer Ingelheim Pharma Gmbh & Co. Kg Use of radical-scavenging compounds for treatment and prevention of NO-dependent microcirculation disorders
DE10119680A1 (de) * 2001-04-20 2002-11-14 Boehringer Ingelheim Pharma Verwendung von Radikalfänger-Verbindungen zur Behandlung und Verhinderung von no-abhängigen Störungen der Mikrozirkulation
RU2322984C2 (ru) 2001-10-05 2008-04-27 Комбинаторкс, Инкорпорейтед Комбинации для лечения иммуновоспалительных расстройств
MY131170A (en) * 2002-03-28 2007-07-31 Nissan Chemical Ind Ltd Therapeutic agent for glomerular disease
DE10335027A1 (de) * 2003-07-31 2005-02-17 Boehringer Ingelheim Pharma Gmbh & Co. Kg Verwendung von Angiotensin II Rezeptor Antagonisten
CA2515266A1 (en) * 2003-02-07 2004-08-19 Boehringer Ingelheim International Gmbh Use of dipyridamole or mopidamole for treatment and prevention of mmp-9-dependent disorders
DE10306179A1 (de) * 2003-02-13 2004-08-26 Boehringer Ingelheim Pharma Gmbh & Co. Kg Verwendung von Dipyridamol in Kombination mit Acetylsalicylsäure und einem Angiotensin II-Antagonisten zur Schlaganfall-Prophylaxe
KR20060007034A (ko) * 2003-04-24 2006-01-23 베링거 인겔하임 인터내셔날 게엠베하 혈전색전증 질환 및 트롬빈의 과형성 및/또는 트롬빈수용체의 상승된 발현에 의해 유발된 질환 및 장애를치료하고 예방하기 위한, 디피리다몰 또는 모피다몰의 용도
JP2005060359A (ja) * 2003-08-13 2005-03-10 Boehringer Ingelheim Pharma Gmbh & Co Kg 血管系病態の治療及び予防のためのジピリダモール、アセチルサリチル酸及びアンギオテンシンｉｉ拮抗薬の使用
TW200517114A (en) * 2003-10-15 2005-06-01 Combinatorx Inc Methods and reagents for the treatment of immunoinflammatory disorders
RU2006143838A (ru) 2004-05-13 2008-06-20 БЕРИНГЕР ИНГЕЛЬХАЙМ ИНТЕРНАЦИОНАЛЬ ГмбХ (DE) Применение дипиридамола для лечения устойчивости к ингибиторам тромбоцитов
JP4880591B2 (ja) 2004-06-04 2012-02-22 テバ ファーマシューティカル インダストリーズ リミティド イルベサルタンを含む医薬組成物
ATE390138T1 (de) * 2006-02-09 2008-04-15 Teva Pharma Dipyridamol enthaltende zusammensetzungen mit verlängerter freisetzung und verfahren zu deren herstellung
US20100062066A1 (en) * 2006-11-14 2010-03-11 Acusphere, Inc Formulations of Tetrahydropyridine Antiplatelet Agents for Parenteral or Oral Administration
EP2991634A1 (en) 2013-04-30 2016-03-09 Otitopic Inc. Dry powder formulations and methods of use
TW201503900A (zh) * 2013-07-29 2015-02-01 ren-zheng Lin 增強治療急性中風之抗血小板藥物之遞送方法及其組合物
AU2016212527B2 (en) * 2015-01-28 2019-03-07 Realinn Life Science Limited Compounds for enhancing PPARgamma expression and nuclear translocation and therapeutic use thereof
KR101736832B1 (ko) 2017-02-28 2017-05-17 초당약품공업 주식회사 디피리다몰을 유효 성분으로 함유하는 신장 질환 치료용 의약 조성물
CN114432451B (zh) * 2018-12-21 2024-02-09 广州市妇女儿童医疗中心 胃肠道疾病的免疫机制及治疗药物
CN111346228B (zh) * 2018-12-21 2022-01-14 广州市妇女儿童医疗中心 胃肠道疾病的免疫机制及治疗药物

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CZ20021487A3 (cs) 2002-10-16
NZ518525A (en) 2004-04-30
HK1048597A1 (zh) 2003-04-11
IL148974A0 (en) 2002-11-10
CN100411620C (zh) 2008-08-20
AU1272101A (en) 2001-05-08
CA2387486C (en) 2009-07-21
EA200200448A1 (ru) 2002-10-31
NO20021784D0 (no) 2002-04-16
HUP0203249A3 (en) 2004-12-28
JP2003512431A (ja) 2003-04-02
EP1225900A1 (en) 2002-07-31
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TR200201089T2 (tr) 2002-09-23
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HUP0203249A2 (hu) 2003-01-28
BR0014946A (pt) 2002-06-18
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AU784124B2 (en) 2006-02-09
US20030149058A1 (en) 2003-08-07
BG106609A (bg) 2003-02-28
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