EE05274B1 - Androgeensed 7-asendatud 11-halogenosteroidid ja neid sisaldavad farmatseutilised kompositsioonid - Google Patents
Androgeensed 7-asendatud 11-halogenosteroidid ja neid sisaldavad farmatseutilised kompositsioonidInfo
- Publication number
- EE05274B1 EE05274B1 EEP200300346A EEP200300346A EE05274B1 EE 05274 B1 EE05274 B1 EE 05274B1 EE P200300346 A EEP200300346 A EE P200300346A EE P200300346 A EEP200300346 A EE P200300346A EE 05274 B1 EE05274 B1 EE 05274B1
- Authority
- EE
- Estonia
- Prior art keywords
- androgenic
- substituted
- pharmaceutical compositions
- compositions containing
- halo steroids
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J1/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, not substituted in position 17 beta by a carbon atom, e.g. estrane, androstane
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J1/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, not substituted in position 17 beta by a carbon atom, e.g. estrane, androstane
- C07J1/0051—Estrane derivatives
- C07J1/0066—Estrane derivatives substituted in position 17 beta not substituted in position 17 alfa
- C07J1/007—Estrane derivatives substituted in position 17 beta not substituted in position 17 alfa the substituent being an OH group free esterified or etherified
- C07J1/0074—Esters
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A61P15/10—Drugs for genital or sexual disorders; Contraceptives for impotence
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A61P15/12—Drugs for genital or sexual disorders; Contraceptives for climacteric disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A61P15/16—Masculine contraceptives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/24—Drugs for disorders of the endocrine system of the sex hormones
- A61P5/26—Androgens
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J1/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, not substituted in position 17 beta by a carbon atom, e.g. estrane, androstane
- C07J1/0003—Androstane derivatives
- C07J1/0018—Androstane derivatives substituted in position 17 beta, not substituted in position 17 alfa
- C07J1/0022—Androstane derivatives substituted in position 17 beta, not substituted in position 17 alfa the substituent being an OH group free esterified or etherified
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J1/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, not substituted in position 17 beta by a carbon atom, e.g. estrane, androstane
- C07J1/0003—Androstane derivatives
- C07J1/0018—Androstane derivatives substituted in position 17 beta, not substituted in position 17 alfa
- C07J1/0022—Androstane derivatives substituted in position 17 beta, not substituted in position 17 alfa the substituent being an OH group free esterified or etherified
- C07J1/0025—Esters
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J1/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, not substituted in position 17 beta by a carbon atom, e.g. estrane, androstane
- C07J1/0051—Estrane derivatives
- C07J1/0066—Estrane derivatives substituted in position 17 beta not substituted in position 17 alfa
- C07J1/007—Estrane derivatives substituted in position 17 beta not substituted in position 17 alfa the substituent being an OH group free esterified or etherified
Landscapes
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- General Chemical & Material Sciences (AREA)
- Endocrinology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Engineering & Computer Science (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Public Health (AREA)
- Reproductive Health (AREA)
- Diabetes (AREA)
- Gynecology & Obstetrics (AREA)
- Steroid Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE10104327A DE10104327A1 (de) | 2001-01-24 | 2001-01-24 | 11beta-Halogensteroide, deren Herstellung und Verwendung zur Herstellung von Arzneimitteln sowie 11beta-Halogensteroide enthaltende pharmazeutische Präparate |
| PCT/EP2002/000722 WO2002059139A1 (en) | 2001-01-24 | 2002-01-24 | Androgenic 7-substituted 11-halogen steroids |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| EE200300346A EE200300346A (et) | 2003-12-15 |
| EE05274B1 true EE05274B1 (et) | 2010-02-15 |
Family
ID=7672351
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| EEP200300346A EE05274B1 (et) | 2001-01-24 | 2002-01-24 | Androgeensed 7-asendatud 11-halogenosteroidid ja neid sisaldavad farmatseutilised kompositsioonid |
Country Status (35)
| Country | Link |
|---|---|
| US (1) | US7361645B2 (da) |
| EP (1) | EP1353938B1 (da) |
| JP (1) | JP4339591B2 (da) |
| KR (1) | KR100728088B1 (da) |
| CN (1) | CN1234721C (da) |
| AR (1) | AR053299A1 (da) |
| AT (1) | ATE386045T1 (da) |
| AU (1) | AU2002238516B2 (da) |
| BG (1) | BG66133B1 (da) |
| BR (1) | BR0206653A (da) |
| CA (1) | CA2434187C (da) |
| CY (1) | CY1110377T1 (da) |
| CZ (1) | CZ303553B6 (da) |
| DE (2) | DE10104327A1 (da) |
| DK (1) | DK1353938T3 (da) |
| EA (1) | EA006674B1 (da) |
| EE (1) | EE05274B1 (da) |
| ES (1) | ES2300431T3 (da) |
| HK (1) | HK1064678A1 (da) |
| HR (1) | HRP20030661B1 (da) |
| HU (1) | HUP0303020A3 (da) |
| IL (2) | IL156807A0 (da) |
| MX (1) | MXPA03006578A (da) |
| NO (1) | NO325754B1 (da) |
| NZ (1) | NZ527041A (da) |
| PE (1) | PE20020848A1 (da) |
| PL (1) | PL207582B1 (da) |
| PT (1) | PT1353938E (da) |
| RS (1) | RS50740B (da) |
| SK (1) | SK287444B6 (da) |
| TW (1) | TWI333494B (da) |
| UA (1) | UA75907C2 (da) |
| UY (1) | UY27133A1 (da) |
| WO (1) | WO2002059139A1 (da) |
| ZA (1) | ZA200306537B (da) |
Families Citing this family (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE10234525A1 (de) * | 2002-07-25 | 2004-02-05 | Schering Ag | Zusammensetzung, enthaltend ein androgenes 11ß-Halogensteroid und ein Gestagen sowie männliches Kontrazeptivum auf Basis dieser Zusammensetzung |
| DE10233723A1 (de) | 2002-07-24 | 2004-02-12 | Schering Ag | Mikrobiologische Verfahren zur Herstellung von 7α-substituierten 11α-Hydroxysteroiden, daraus herstellbare 7α,17α-substituierte 11β-Halogensteroide, deren Herstellungsverfahren und Verwendung sowie pharmazeutische Präparate, die diese Verbindungen enthalten, sowie daraus herstellbare 7α-substituierte Estra-1,3,5(10)-triene |
| MXPA05001024A (es) * | 2002-07-24 | 2005-05-16 | Schering Ag | Metodo microbiologico para la produccion de 11 alfa-hdiroxiesteroides sustituidos en la posicion 7 alfa. |
| JP2006502997A (ja) * | 2002-07-25 | 2006-01-26 | シエーリング アクチエンゲゼルシャフト | アンドロゲン１１β‐ハロゲンステロイドおよびゲスタゲンを含有する組成物ならびにこの組成物に基づく男性用避妊薬 |
| JO2492B1 (en) * | 2003-04-28 | 2009-10-05 | شيرينج ايه جي | A pharmaceutical formula in the form of aqueous gel for the skin use of its active ingredients |
| US7879357B2 (en) * | 2003-04-28 | 2011-02-01 | Bayer Schering Pharma Ag | Pharmaceutical composition in the form of a hydrogel for transdermal administration of active ingredients |
| CN106188202B (zh) * | 2014-10-08 | 2017-10-24 | 常州大学 | 副产3，17‑二醇物含量大幅降低的合成睾酮方法 |
| TWI530504B (zh) * | 2014-12-01 | 2016-04-21 | 臺灣永光化學工業股份有限公司 | 烷基酸睾酮化合物之合成方法 |
| US20220411460A1 (en) * | 2021-06-29 | 2022-12-29 | Board Of Regents, The University Of Texas System | Modified glucocorticoids |
Family Cites Families (17)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB863661A (en) | 1958-06-06 | 1961-03-22 | Upjohn Co | Improvements in or relating to steroids and the manufacture thereof |
| CH380118A (de) * | 1959-06-17 | 1964-07-31 | Ciba Geigy | Neue Halogenandrostenverbindungen und Verfahren zu deren Herstellung |
| FR1489519A (fr) | 1965-08-16 | 1967-07-21 | Glaxo Lab Ltd | Procédé de préparation de nouveaux 19-nor-stéroïdes et produits obtenus |
| GB1159434A (en) * | 1965-08-16 | 1969-07-23 | Glaxo Lab Ltd | 11beta&;-Fluoro-19-nor-Steroids |
| US3665021A (en) | 1966-07-29 | 1972-05-23 | Glaxo Lab Ltd | 9alpha-unsubstituted-11beta-chloro-l9 nos-steroids |
| GB1260463A (en) | 1968-01-29 | 1972-01-19 | Glaxo Lab Ltd | 11beta-BROMO-19-NOR-STEROIDS |
| DE2410443A1 (de) * | 1974-03-01 | 1975-09-11 | Schering Ag | 11beta-fluor-androstene |
| DE2410442A1 (de) | 1974-03-01 | 1975-09-11 | Schering Ag | Verfahren zur herstellung von 11-fluorandrostenen |
| DE3214690A1 (de) * | 1982-04-16 | 1983-10-27 | Schering AG, 1000 Berlin und 4709 Bergkamen | 11ss-chlor-(delta)(pfeil hoch)1(pfeil hoch)(pfeil hoch)5(pfeil hoch)-steroide, verfahren zu ihrer herstellung und diese enthaltende pharmazeutische praeparate |
| GB8721384D0 (en) * | 1987-09-11 | 1987-10-21 | Erba Farmitalia | 17-substituted andro-sta-1 4-dien-3-one derivatives |
| US5342834A (en) * | 1989-04-07 | 1994-08-30 | The Population Council, Inc. | Method for androgen supplementation |
| US6767902B2 (en) * | 1997-09-17 | 2004-07-27 | The Population Council, Inc. | Androgen as a male contraceptive and non-contraceptive androgen replacement |
| US20020012694A1 (en) * | 1997-09-17 | 2002-01-31 | Alfred J. Moo-Young | Transdermal administration of ment |
| US5952319A (en) * | 1997-11-26 | 1999-09-14 | Research Triangle Institute | Androgenic steroid compounds and a method of making and using the same |
| JP4749550B2 (ja) * | 1999-03-08 | 2011-08-17 | ナームローゼ・フエンノートチヤツプ・オルガノン | アンドロゲンとしての１４β，１７α−ヒドロキシメチルアンドロスタン誘導体 |
| US6756366B1 (en) * | 1999-04-06 | 2004-06-29 | Akzo Nobel N.V. | Orally active androgens |
| DE19959696A1 (de) * | 1999-12-08 | 2001-06-21 | Jenapharm Gmbh | Ungesättigte 14,15-Cyclopropano-Androstane, Verfahren zu ihrer Herstellung und diese Verbindungen enthaltende pharmazeutische Zusammensetzungen |
-
2001
- 2001-01-24 DE DE10104327A patent/DE10104327A1/de not_active Ceased
-
2002
- 2002-01-24 PL PL361730A patent/PL207582B1/pl not_active IP Right Cessation
- 2002-01-24 WO PCT/EP2002/000722 patent/WO2002059139A1/en active IP Right Grant
- 2002-01-24 AU AU2002238516A patent/AU2002238516B2/en not_active Ceased
- 2002-01-24 AR ARP020100238A patent/AR053299A1/es active IP Right Grant
- 2002-01-24 EE EEP200300346A patent/EE05274B1/xx not_active IP Right Cessation
- 2002-01-24 SK SK954-2003A patent/SK287444B6/sk not_active IP Right Cessation
- 2002-01-24 DK DK02704667T patent/DK1353938T3/da active
- 2002-01-24 CZ CZ20032006A patent/CZ303553B6/cs not_active IP Right Cessation
- 2002-01-24 RS YUP-594/03A patent/RS50740B/sr unknown
- 2002-01-24 HU HU0303020A patent/HUP0303020A3/hu unknown
- 2002-01-24 EA EA200300756A patent/EA006674B1/ru not_active IP Right Cessation
- 2002-01-24 DE DE60224982T patent/DE60224982T2/de not_active Expired - Lifetime
- 2002-01-24 PE PE2002000053A patent/PE20020848A1/es not_active Application Discontinuation
- 2002-01-24 UA UA2003087912A patent/UA75907C2/uk unknown
- 2002-01-24 EP EP02704667A patent/EP1353938B1/en not_active Expired - Lifetime
- 2002-01-24 BR BR0206653-0A patent/BR0206653A/pt not_active IP Right Cessation
- 2002-01-24 TW TW091101142A patent/TWI333494B/zh not_active IP Right Cessation
- 2002-01-24 MX MXPA03006578A patent/MXPA03006578A/es active IP Right Grant
- 2002-01-24 AT AT02704667T patent/ATE386045T1/de active
- 2002-01-24 KR KR1020037009732A patent/KR100728088B1/ko not_active IP Right Cessation
- 2002-01-24 PT PT02704667T patent/PT1353938E/pt unknown
- 2002-01-24 CN CNB028040686A patent/CN1234721C/zh not_active Expired - Fee Related
- 2002-01-24 JP JP2002559441A patent/JP4339591B2/ja not_active Expired - Fee Related
- 2002-01-24 US US10/467,352 patent/US7361645B2/en not_active Expired - Fee Related
- 2002-01-24 UY UY27133A patent/UY27133A1/es not_active Application Discontinuation
- 2002-01-24 ES ES02704667T patent/ES2300431T3/es not_active Expired - Lifetime
- 2002-01-24 CA CA002434187A patent/CA2434187C/en not_active Expired - Fee Related
- 2002-01-24 NZ NZ527041A patent/NZ527041A/en not_active IP Right Cessation
- 2002-01-24 IL IL15680702A patent/IL156807A0/xx active IP Right Grant
-
2003
- 2003-07-07 IL IL156807A patent/IL156807A/en not_active IP Right Cessation
- 2003-07-23 NO NO20033321A patent/NO325754B1/no not_active IP Right Cessation
- 2003-07-23 BG BG108023A patent/BG66133B1/bg unknown
- 2003-08-20 HR HR20030661A patent/HRP20030661B1/xx not_active IP Right Cessation
- 2003-08-21 ZA ZA200306537A patent/ZA200306537B/en unknown
-
2004
- 2004-09-28 HK HK04107492A patent/HK1064678A1/xx not_active IP Right Cessation
-
2008
- 2008-05-13 CY CY20081100508T patent/CY1110377T1/el unknown
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| KB4A | Valid patent at the end of a year |
Effective date: 20101231 |
|
| MM4A | Lapsed by not paying the annual fees |
Effective date: 20140124 |