EE03613B1 - Omeprasooli naatriumisool,selle valmistamise protsess,seda sisaldav ravimkoostis ja selle kasutamine seedetrakti häirete ravimiseks - Google Patents

Omeprasooli naatriumisool,selle valmistamise protsess,seda sisaldav ravimkoostis ja selle kasutamine seedetrakti häirete ravimiseks

Info

Publication number
EE03613B1
EE03613B1 EEP199900593A EEP9900593A EE03613B1 EE 03613 B1 EE03613 B1 EE 03613B1 EE P199900593 A EEP199900593 A EE P199900593A EE P9900593 A EEP9900593 A EE P9900593A EE 03613 B1 EE03613 B1 EE 03613B1
Authority
EE
Estonia
Prior art keywords
preparation
treatment
pharmaceutical composition
composition containing
gastrointestinal disorders
Prior art date
Application number
EEP199900593A
Other languages
English (en)
Estonian (et)
Inventor
Gustavsson Anders
Kjellbom Kristina
Ymn Ingvar
Original Assignee
Astra Aktiebolag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Astra Aktiebolag filed Critical Astra Aktiebolag
Publication of EE9900593A publication Critical patent/EE9900593A/xx
Publication of EE03613B1 publication Critical patent/EE03613B1/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
EEP199900593A 1997-06-27 1998-06-11 Omeprasooli naatriumisool,selle valmistamise protsess,seda sisaldav ravimkoostis ja selle kasutamine seedetrakti häirete ravimiseks EE03613B1 (et)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
SE9702483A SE510643C2 (sv) 1997-06-27 1997-06-27 Termodynamiskt stabil omeprazol natrium form B
PCT/SE1998/001124 WO1999000380A1 (en) 1997-06-27 1998-06-11 Omeprazole sodium salt

Publications (2)

Publication Number Publication Date
EE9900593A EE9900593A (et) 2000-08-15
EE03613B1 true EE03613B1 (et) 2002-02-15

Family

ID=20407555

Family Applications (1)

Application Number Title Priority Date Filing Date
EEP199900593A EE03613B1 (et) 1997-06-27 1998-06-11 Omeprasooli naatriumisool,selle valmistamise protsess,seda sisaldav ravimkoostis ja selle kasutamine seedetrakti häirete ravimiseks

Country Status (35)

Country Link
US (1) US6207188B1 (ar)
EP (2) EP0991641B1 (ar)
JP (1) JP3377218B2 (ar)
KR (1) KR100580987B1 (ar)
CN (1) CN1134432C (ar)
AR (1) AR013350A1 (ar)
AT (1) ATE233756T1 (ar)
AU (1) AU750239B2 (ar)
BR (1) BR9810483A (ar)
CA (1) CA2294614C (ar)
CZ (1) CZ296723B6 (ar)
DE (1) DE69811892T2 (ar)
DK (1) DK0991641T3 (ar)
EE (1) EE03613B1 (ar)
EG (1) EG24224A (ar)
ES (1) ES2191944T3 (ar)
HK (1) HK1026699A1 (ar)
HU (1) HU227976B1 (ar)
ID (1) ID24829A (ar)
IL (2) IL133559A0 (ar)
IS (1) IS1946B (ar)
MY (1) MY127871A (ar)
NO (1) NO318245B1 (ar)
NZ (1) NZ501929A (ar)
PL (1) PL190869B1 (ar)
PT (1) PT991641E (ar)
RU (1) RU2186778C2 (ar)
SA (1) SA98190410B1 (ar)
SE (1) SE510643C2 (ar)
SK (1) SK283958B6 (ar)
TR (1) TR199903270T2 (ar)
TW (1) TW483758B (ar)
UA (1) UA58556C2 (ar)
WO (1) WO1999000380A1 (ar)
ZA (1) ZA985317B (ar)

Families Citing this family (39)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5840737A (en) 1996-01-04 1998-11-24 The Curators Of The University Of Missouri Omeprazole solution and method for using same
US6489346B1 (en) 1996-01-04 2002-12-03 The Curators Of The University Of Missouri Substituted benzimidazole dosage forms and method of using same
DK0909323T3 (da) 1996-01-04 2007-05-21 Novartis Vaccines & Diagnostic Helicobacter pylori-bakterioferritin
SE510643C2 (sv) 1997-06-27 1999-06-14 Astra Ab Termodynamiskt stabil omeprazol natrium form B
SE9900274D0 (sv) * 1999-01-28 1999-01-28 Astra Ab New compound
IL145220A0 (en) * 1999-05-20 2002-06-30 Par Pharmaceutical Inc Stabilized composition based on pyridinyl-sulfinyl-benzimidazoles and process
SE9903831D0 (sv) 1999-10-22 1999-10-22 Astra Ab Formulation of substituted benzimidazoles
SE0000774D0 (sv) 2000-03-08 2000-03-08 Astrazeneca Ab New formulation
SE0000773D0 (sv) * 2000-03-08 2000-03-08 Astrazeneca Ab New formulation
US20030212274A1 (en) * 2000-05-15 2003-11-13 Bakthavathsalan Vijayaraghavan Novel amorphous form of omeprazole salts
CA2775616C (en) 2000-08-04 2013-09-17 Takeda Pharmaceutical Company Limited Salts of benzimidazole compound and application thereof
AU2001278755A1 (en) * 2000-08-18 2002-03-04 Takeda Chemical Industries Ltd. Injections
US8206741B2 (en) 2001-06-01 2012-06-26 Pozen Inc. Pharmaceutical compositions for the coordinated delivery of NSAIDs
WO2002098352A2 (en) 2001-06-01 2002-12-12 Pozen Inc. PHARMACEUTICAL COMPOSITIONS FOR THE COORDINATED DELIVERY OF NSAIDs
KR100433735B1 (ko) * 2001-06-27 2004-06-04 주식회사 씨트리 결정형 ⅰ을 갖는 란소프라졸의 제조방법
SE0102993D0 (sv) 2001-09-07 2001-09-07 Astrazeneca Ab New self emulsifying drug delivery system
EA200500673A1 (ru) * 2002-10-22 2005-12-29 Рэнбакси Лабораториз Лимитед Аморфная форма соли эзомепразола, способ ее получения и фармацевтическая композиция на её основе
CN1842525A (zh) 2003-05-05 2006-10-04 兰贝克赛实验室有限公司 苯并咪唑衍生物的钡盐
US8993599B2 (en) 2003-07-18 2015-03-31 Santarus, Inc. Pharmaceutical formulations useful for inhibiting acid secretion and methods for making and using them
US8906940B2 (en) 2004-05-25 2014-12-09 Santarus, Inc. Pharmaceutical formulations useful for inhibiting acid secretion and methods for making and using them
FR2871800B1 (fr) * 2004-06-17 2006-08-25 Sidem Pharma Sa Sa Sel de sodium monohydrate du s-tenatoprazole et application en therapeutique
WO2006001753A1 (en) * 2004-06-24 2006-01-05 Astrazeneca Ab New process for the preparation of crystal modifications for use in the preparation of esomeprazole sodium salt
US20060160783A1 (en) * 2004-12-30 2006-07-20 Transform Pharmaceuticals, Inc. Novel omeprazole forms and related methods
EP1907375B1 (en) * 2005-06-08 2013-07-24 LEK Pharmaceuticals d.d. Crystalline solvate of omeprazole sodium
CA2736547C (en) 2008-09-09 2016-11-01 Pozen Inc. Method for delivering a pharmaceutical composition to patient in need thereof
CN101412710B (zh) * 2008-12-16 2010-04-21 海南百那医药发展有限公司 一种奥美拉唑钠化合物及其制法
EA021112B1 (ru) * 2009-06-25 2015-04-30 Поузен Инк. Способ лечения боли и/или воспаления у пациента, нуждающегося в аспириновой терапии
AU2010263304A1 (en) 2009-06-25 2012-02-02 Astrazeneca Ab Method for treating a patient at risk for developing an NSAID-associated ulcer
CN102351846B (zh) * 2011-09-07 2012-08-22 周晓东 一种新的奥美拉唑钠化合物及其药物组合物
CN102319223B (zh) * 2011-09-21 2013-06-19 石药集团欧意药业有限公司 一种埃索美拉唑冻干制剂及其制备方法
CN102512380B (zh) * 2011-12-20 2013-04-17 海南锦瑞制药股份有限公司 一种以奥美拉唑钠为活性成分的冻干粉针剂及其制备方法
MX2014007935A (es) 2011-12-28 2014-11-14 Pozen Inc Composiciones y metodos mejorados para el suministro de omeprazol y de acido acetilsalicilico.
CN102827147B (zh) * 2012-09-13 2013-08-07 山东罗欣药业股份有限公司 一种奥美拉唑钠晶体化合物及含有该晶体化合物的药物组合物
CN102871973A (zh) * 2012-10-16 2013-01-16 浙江亚太药业股份有限公司 一种奥美拉唑钠冻干制剂及其制备方法
CN103012371B (zh) * 2013-01-05 2014-02-12 宁辉 奥美拉唑钠结晶化合物、其制备方法及其药物组合物
CN103570687B (zh) * 2013-11-15 2015-01-07 悦康药业集团有限公司 一种奥美拉唑钠晶体化合物
CN104788426B (zh) * 2015-04-02 2015-12-30 天津大学 一种奥美拉唑钠半水合物及其制备方法
WO2024075017A1 (en) 2022-10-04 2024-04-11 Zabirnyk Arsenii Inhibition of aortic valve calcification
CN116041325A (zh) * 2022-12-09 2023-05-02 山东北大高科华泰制药有限公司 稳定化质子泵抑制剂的方法

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2719916C2 (de) * 1977-05-04 1987-03-19 Kali-Chemie Pharma Gmbh, 3000 Hannover Verfahren zur Herstellung von 2,9-Dioxatricyclo[4,3,1,0↑3↑↑,↑↑7↑]decanen
SE7804231L (sv) 1978-04-14 1979-10-15 Haessle Ab Magsyrasekretionsmedel
SE8301182D0 (sv) * 1983-03-04 1983-03-04 Haessle Ab Novel compounds
GB2189698A (en) 1986-04-30 1987-11-04 Haessle Ab Coated omeprazole tablets
ES2023778A6 (es) * 1990-12-12 1992-02-01 Genesis Para La Investigacion Procedimiento para preparar sales alcalinas del omeprazol
SE9301830D0 (sv) * 1993-05-28 1993-05-28 Ab Astra New compounds
WO1995032957A1 (en) * 1994-05-27 1995-12-07 Astra Aktiebolag Novel ethoxycarbonyloxymethyl derivatives of substituted benzimidazoles
EP0723436B1 (en) 1994-07-08 2001-09-26 AstraZeneca AB Multiple unit tableted dosage form i
SE504459C2 (sv) * 1994-07-15 1997-02-17 Astra Ab Förfarande för framställning av substituerade sulfoxider
CN1042423C (zh) * 1995-05-25 1999-03-10 常州市第四制药厂 奥美拉唑盐水合物及其制备方法
WO1998040377A1 (en) * 1997-03-07 1998-09-17 A/S Gea Farmaceutisk Fabrik Process for the preparation of 2-[[(2-pyridinyl)methyl]sulfinyl]-1h-benzimidazoles and novel compounds of use for such purpose
EP0968205A1 (en) * 1997-03-07 2000-01-05 A/S GEA Farmaceutisk Fabrik Process for the preparation of 2- (2-pyridinyl)methyl]sulfinyl]-1h-benzimidazoles and novel compounds of use for such purpose
SE510643C2 (sv) 1997-06-27 1999-06-14 Astra Ab Termodynamiskt stabil omeprazol natrium form B

Also Published As

Publication number Publication date
EP0991641B1 (en) 2003-03-05
IS5314A (is) 1999-12-21
JP2001508805A (ja) 2001-07-03
WO1999000380A1 (en) 1999-01-07
ZA985317B (en) 1999-01-11
SE9702483L (sv) 1998-12-28
EP1186602A2 (en) 2002-03-13
IS1946B (is) 2004-10-13
SE9702483D0 (sv) 1997-06-27
SA98190410B1 (ar) 2006-06-10
PL190869B1 (pl) 2006-02-28
NZ501929A (en) 2001-06-29
DK0991641T3 (da) 2003-05-19
KR20010014165A (ko) 2001-02-26
DE69811892D1 (de) 2003-04-10
CA2294614C (en) 2002-01-08
CA2294614A1 (en) 1999-01-07
IL133559A (en) 2006-04-10
UA58556C2 (uk) 2003-08-15
AR013350A1 (es) 2000-12-27
AU750239B2 (en) 2002-07-11
HUP0003017A3 (en) 2002-01-28
CZ296723B6 (cs) 2006-05-17
HU227976B1 (en) 2012-07-30
EG24224A (en) 2008-11-10
ID24829A (id) 2000-08-24
HUP0003017A2 (hu) 2001-06-28
BR9810483A (pt) 2000-09-12
DE69811892T2 (de) 2004-03-04
SK172999A3 (en) 2000-07-11
TW483758B (en) 2002-04-21
PT991641E (pt) 2003-06-30
AU8135398A (en) 1999-01-19
NO996440D0 (no) 1999-12-23
JP3377218B2 (ja) 2003-02-17
KR100580987B1 (ko) 2006-05-17
RU2186778C2 (ru) 2002-08-10
US6207188B1 (en) 2001-03-27
HK1026699A1 (en) 2000-12-22
EP0991641A1 (en) 2000-04-12
CN1134432C (zh) 2004-01-14
ES2191944T3 (es) 2003-09-16
TR199903270T2 (xx) 2000-07-21
IL133559A0 (en) 2001-04-30
SE510643C2 (sv) 1999-06-14
SK283958B6 (sk) 2004-06-08
NO318245B1 (no) 2005-02-21
EP1186602A3 (en) 2002-03-27
ATE233756T1 (de) 2003-03-15
NO996440L (no) 2000-02-08
PL337735A1 (en) 2000-08-28
MY127871A (en) 2006-12-29
CZ469999A3 (cs) 2000-08-16
CN1261362A (zh) 2000-07-26
EE9900593A (et) 2000-08-15

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