ECSP088220A - Uso de dosis única de moléculas de unión específica cd20 - Google Patents
Uso de dosis única de moléculas de unión específica cd20Info
- Publication number
- ECSP088220A ECSP088220A EC2008008220A ECSP088220A ECSP088220A EC SP088220 A ECSP088220 A EC SP088220A EC 2008008220 A EC2008008220 A EC 2008008220A EC SP088220 A ECSP088220 A EC SP088220A EC SP088220 A ECSP088220 A EC SP088220A
- Authority
- EC
- Ecuador
- Prior art keywords
- single dose
- specific union
- molecules
- union molecules
- specific
- Prior art date
Links
Classifications
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
- C07K16/2887—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against CD20
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/12—Drugs for disorders of the urinary system of the kidneys
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P21/00—Drugs for disorders of the muscular or neuromuscular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
- A61P29/02—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID] without antiinflammatory effect
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
- C07K2317/24—Immunoglobulins specific features characterized by taxonomic origin containing regions, domains or residues from different species, e.g. chimeric, humanized or veneered
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
- C07K2317/52—Constant or Fc region; Isotype
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/60—Immunoglobulins specific features characterized by non-natural combinations of immunoglobulin fragments
- C07K2317/62—Immunoglobulins specific features characterized by non-natural combinations of immunoglobulin fragments comprising only variable region components
- C07K2317/622—Single chain antibody (scFv)
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
- C07K2317/71—Decreased effector function due to an Fc-modification
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
- C07K2317/73—Inducing cell death, e.g. apoptosis, necrosis or inhibition of cell proliferation
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
- C07K2317/73—Inducing cell death, e.g. apoptosis, necrosis or inhibition of cell proliferation
- C07K2317/732—Antibody-dependent cellular cytotoxicity [ADCC]
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
- C07K2317/73—Inducing cell death, e.g. apoptosis, necrosis or inhibition of cell proliferation
- C07K2317/734—Complement-dependent cytotoxicity [CDC]
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Immunology (AREA)
- Epidemiology (AREA)
- Rheumatology (AREA)
- Biophysics (AREA)
- Biochemistry (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Genetics & Genomics (AREA)
- Pain & Pain Management (AREA)
- Neurology (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Physical Education & Sports Medicine (AREA)
- Neurosurgery (AREA)
- Heart & Thoracic Surgery (AREA)
- Oncology (AREA)
- Biomedical Technology (AREA)
- Communicable Diseases (AREA)
- Cardiology (AREA)
- Microbiology (AREA)
- Mycology (AREA)
- Urology & Nephrology (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US70249805P | 2005-07-25 | 2005-07-25 | |
US70287505P | 2005-07-27 | 2005-07-27 |
Publications (1)
Publication Number | Publication Date |
---|---|
ECSP088220A true ECSP088220A (es) | 2008-03-26 |
Family
ID=37683925
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
EC2008008220A ECSP088220A (es) | 2005-07-25 | 2008-02-25 | Uso de dosis única de moléculas de unión específica cd20 |
Country Status (18)
Country | Link |
---|---|
US (1) | US20080213273A1 (de) |
EP (2) | EP2415483A1 (de) |
JP (1) | JP2009502936A (de) |
KR (1) | KR20080047540A (de) |
CN (1) | CN101267836A (de) |
AU (1) | AU2006272597A1 (de) |
BR (1) | BRPI0614183A2 (de) |
CA (1) | CA2616386A1 (de) |
CO (1) | CO6220975A2 (de) |
CR (1) | CR9763A (de) |
EC (1) | ECSP088220A (de) |
IL (1) | IL188762A0 (de) |
NO (1) | NO20080318L (de) |
NZ (1) | NZ565173A (de) |
PE (1) | PE20081653A1 (de) |
RU (2) | RU2421242C2 (de) |
TW (1) | TW200806320A (de) |
WO (1) | WO2007014238A2 (de) |
Families Citing this family (76)
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US20030133939A1 (en) | 2001-01-17 | 2003-07-17 | Genecraft, Inc. | Binding domain-immunoglobulin fusion proteins |
US7829084B2 (en) * | 2001-01-17 | 2010-11-09 | Trubion Pharmaceuticals, Inc. | Binding constructs and methods for use thereof |
US7754208B2 (en) | 2001-01-17 | 2010-07-13 | Trubion Pharmaceuticals, Inc. | Binding domain-immunoglobulin fusion proteins |
NI200800032A (es) | 2005-07-25 | 2009-03-23 | Reducción de célula b utilizando moléculas de unión específicas cd37 y cd20 | |
MX2008015524A (es) | 2006-06-12 | 2009-01-13 | Trubion Pharmaceuticals Inc | Proteinas de union multivalentes monocatenarias con funcion efectora. |
WO2008109503A1 (en) * | 2007-03-02 | 2008-09-12 | Mdrna, Inc. | Nucleic acid compounds for inhibiting ms4a1 gene expression and uses thereof |
GB0707208D0 (en) * | 2007-04-13 | 2007-05-23 | Istituto Superiore Di Sanito | Novel disease treatments |
EP2164871A2 (de) * | 2007-06-12 | 2010-03-24 | Wyeth a Corporation of the State of Delaware | Therapeutische anti-cd20-zusammensetzungen und -verfahren |
GB0718684D0 (en) * | 2007-09-24 | 2007-10-31 | Roche Products Ltd | Treatment method |
EP2077281A1 (de) * | 2008-01-02 | 2009-07-08 | Bergen Teknologioverforing AS | Anti-CD20-Antikörper oder Fragmente davon zur Behandlung von chronischen Ermüdungssyndrom |
EP2096438A1 (de) * | 2008-02-28 | 2009-09-02 | Martin Thurnher | Verfahren zur Prognose des Status von Patienten |
SI2132228T1 (sl) * | 2008-04-11 | 2011-10-28 | Emergent Product Dev Seatle | CD37 imunoterapevtik in kombinacija z njegovim bifunkcionalnim kemoterapevtikom |
TW201014605A (en) | 2008-09-16 | 2010-04-16 | Genentech Inc | Methods for treating progressive multiple sclerosis |
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KR20110139216A (ko) | 2009-03-11 | 2011-12-28 | 와이어쓰 엘엘씨 | 소형 모듈형 면역약제 단백질의 정제 방법 |
WO2011028952A1 (en) | 2009-09-02 | 2011-03-10 | Xencor, Inc. | Compositions and methods for simultaneous bivalent and monovalent co-engagement of antigens |
MX353186B (es) * | 2009-09-03 | 2018-01-05 | Genentech Inc | Metodos para el tratamiento, diagnosis y monitoreo de artritis reumatoide. |
WO2011044205A1 (en) * | 2009-10-07 | 2011-04-14 | Genentech, Inc. | Methods for treating, diagnosing, and monitoring lupus |
WO2012016227A2 (en) | 2010-07-29 | 2012-02-02 | Xencor, Inc. | Antibodies with modified isoelectric points |
US10851178B2 (en) | 2011-10-10 | 2020-12-01 | Xencor, Inc. | Heterodimeric human IgG1 polypeptides with isoelectric point modifications |
EP3620473A1 (de) | 2013-01-14 | 2020-03-11 | Xencor, Inc. | Neuartige heterodimere proteine |
US10487155B2 (en) | 2013-01-14 | 2019-11-26 | Xencor, Inc. | Heterodimeric proteins |
US9701759B2 (en) | 2013-01-14 | 2017-07-11 | Xencor, Inc. | Heterodimeric proteins |
US10131710B2 (en) | 2013-01-14 | 2018-11-20 | Xencor, Inc. | Optimized antibody variable regions |
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US10968276B2 (en) | 2013-03-12 | 2021-04-06 | Xencor, Inc. | Optimized anti-CD3 variable regions |
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EP3223845B1 (de) | 2014-11-26 | 2021-05-19 | Xencor, Inc. | Cheterodimere antikörper zur bindung von cd3 und cd20 |
US10259887B2 (en) | 2014-11-26 | 2019-04-16 | Xencor, Inc. | Heterodimeric antibodies that bind CD3 and tumor antigens |
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KR102616360B1 (ko) * | 2021-11-09 | 2023-12-27 | 재단법인 아산사회복지재단 | 염증성 근육병증 진단용 바이오마커 조성물 |
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-
2006
- 2006-07-25 WO PCT/US2006/028961 patent/WO2007014238A2/en active Application Filing
- 2006-07-25 JP JP2008524092A patent/JP2009502936A/ja active Pending
- 2006-07-25 AU AU2006272597A patent/AU2006272597A1/en not_active Abandoned
- 2006-07-25 EP EP11174173A patent/EP2415483A1/de not_active Withdrawn
- 2006-07-25 RU RU2008106902/15A patent/RU2421242C2/ru not_active IP Right Cessation
- 2006-07-25 US US11/493,241 patent/US20080213273A1/en not_active Abandoned
- 2006-07-25 BR BRPI0614183-8A patent/BRPI0614183A2/pt not_active Application Discontinuation
- 2006-07-25 CN CNA2006800344332A patent/CN101267836A/zh active Pending
- 2006-07-25 KR KR1020087004370A patent/KR20080047540A/ko not_active Application Discontinuation
- 2006-07-25 CA CA002616386A patent/CA2616386A1/en not_active Abandoned
- 2006-07-25 NZ NZ565173A patent/NZ565173A/en not_active IP Right Cessation
- 2006-07-25 EP EP06800341A patent/EP1919505A2/de not_active Withdrawn
- 2006-12-19 PE PE2006001629A patent/PE20081653A1/es not_active Application Discontinuation
- 2006-12-22 TW TW095148644A patent/TW200806320A/zh unknown
-
2008
- 2008-01-14 IL IL188762A patent/IL188762A0/en unknown
- 2008-01-18 NO NO20080318A patent/NO20080318L/no not_active Application Discontinuation
- 2008-01-18 CO CO08004589A patent/CO6220975A2/es not_active Application Discontinuation
- 2008-02-25 EC EC2008008220A patent/ECSP088220A/es unknown
- 2008-02-25 CR CR9763A patent/CR9763A/es not_active Application Discontinuation
-
2011
- 2011-01-11 RU RU2011100143/15A patent/RU2011100143A/ru not_active Application Discontinuation
Also Published As
Publication number | Publication date |
---|---|
EP2415483A1 (de) | 2012-02-08 |
AU2006272597A1 (en) | 2007-02-01 |
TW200806320A (en) | 2008-02-01 |
CO6220975A2 (es) | 2010-11-19 |
WO2007014238A3 (en) | 2007-06-21 |
CR9763A (es) | 2009-01-28 |
EP1919505A2 (de) | 2008-05-14 |
CN101267836A (zh) | 2008-09-17 |
IL188762A0 (en) | 2008-08-07 |
RU2008106902A (ru) | 2009-09-10 |
CA2616386A1 (en) | 2007-02-01 |
KR20080047540A (ko) | 2008-05-29 |
RU2421242C2 (ru) | 2011-06-20 |
NZ565173A (en) | 2012-01-12 |
JP2009502936A (ja) | 2009-01-29 |
US20080213273A1 (en) | 2008-09-04 |
RU2011100143A (ru) | 2012-08-10 |
BRPI0614183A2 (pt) | 2011-03-15 |
NO20080318L (no) | 2008-04-02 |
WO2007014238A8 (en) | 2008-02-21 |
WO2007014238A2 (en) | 2007-02-01 |
PE20081653A1 (es) | 2008-11-04 |
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