ECSP066458A - 6-[(sustituido)fenil]triazolopirimidinas como agentes anticancer - Google Patents

6-[(sustituido)fenil]triazolopirimidinas como agentes anticancer

Info

Publication number
ECSP066458A
ECSP066458A EC2006006458A ECSP066458A ECSP066458A EC SP066458 A ECSP066458 A EC SP066458A EC 2006006458 A EC2006006458 A EC 2006006458A EC SP066458 A ECSP066458 A EC SP066458A EC SP066458 A ECSP066458 A EC SP066458A
Authority
EC
Ecuador
Prior art keywords
mammal
compounds
pharmaceutically acceptable
treatment
acceptable salts
Prior art date
Application number
EC2006006458A
Other languages
English (en)
Spanish (es)
Inventor
Yanzhong Wu
Nan Zhang
Semiramis Ayral-Kaloustian
Thai Hiep Nguyen
Wei Tong
Original Assignee
Wyeth Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Wyeth Corp filed Critical Wyeth Corp
Publication of ECSP066458A publication Critical patent/ECSP066458A/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/02—Antineoplastic agents specific for leukemia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/04—Antineoplastic agents specific for metastasis

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Oncology (AREA)
  • Hematology (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
EC2006006458A 2003-09-24 2006-03-24 6-[(sustituido)fenil]triazolopirimidinas como agentes anticancer ECSP066458A (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US50554403P 2003-09-24 2003-09-24

Publications (1)

Publication Number Publication Date
ECSP066458A true ECSP066458A (es) 2006-09-18

Family

ID=34393032

Family Applications (1)

Application Number Title Priority Date Filing Date
EC2006006458A ECSP066458A (es) 2003-09-24 2006-03-24 6-[(sustituido)fenil]triazolopirimidinas como agentes anticancer

Country Status (30)

Country Link
US (1) US7507739B2 (enExample)
EP (1) EP1680425B1 (enExample)
JP (1) JP2007506744A (enExample)
KR (1) KR20060098368A (enExample)
CN (1) CN100519559C (enExample)
AR (1) AR045810A1 (enExample)
AU (1) AU2004276240A1 (enExample)
BR (1) BRPI0414700A (enExample)
CA (1) CA2539252A1 (enExample)
CO (1) CO5690598A2 (enExample)
CR (1) CR8288A (enExample)
CY (1) CY1106392T1 (enExample)
DE (1) DE602004004295T8 (enExample)
DK (1) DK1680425T3 (enExample)
EC (1) ECSP066458A (enExample)
ES (1) ES2279452T3 (enExample)
GT (1) GT200400190A (enExample)
IL (1) IL174281A0 (enExample)
MX (1) MXPA06003206A (enExample)
NO (1) NO20061318L (enExample)
PA (1) PA8613301A1 (enExample)
PE (1) PE20050433A1 (enExample)
PL (1) PL1680425T3 (enExample)
PT (1) PT1680425E (enExample)
RU (1) RU2006107579A (enExample)
SA (1) SA04250302A (enExample)
SI (1) SI1680425T1 (enExample)
TW (1) TW200512211A (enExample)
WO (1) WO2005030775A1 (enExample)
ZA (1) ZA200602387B (enExample)

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NZ523807A (en) * 2000-06-30 2004-09-24 Wyeth Corp Substituted-triazolopyrimidines as anticancer agents
ES2279452T3 (es) 2003-09-24 2007-08-16 Wyeth Holdings Corporation 6-((sustituido)fenil)triazolopirimidinas como agentes antineoplasicos.
US7419982B2 (en) * 2003-09-24 2008-09-02 Wyeth Holdings Corporation Crystalline forms of 5-chloro-6-{2,6-difluoro-4-[3-(methylamino)propoxy]phenyl}-N-[(1S)-2,2,2-trifluoro-1-methylethyl][1,2,4]triazolo[1,5-a]pyrimidin-7-amine salts
MY179926A (en) * 2003-12-08 2020-11-19 Wyeth Corp Process for the preparation of tubulin inhibitors
JP2008543838A (ja) * 2005-06-13 2008-12-04 ワイス チューブリンインヒビターおよびその調製のためのプロセス
CN101193884A (zh) 2005-06-13 2008-06-04 惠氏公司 微管蛋白抑制剂和其制备方法
CN101208289A (zh) * 2005-06-27 2008-06-25 巴斯福股份公司 生产取代的苯基丙二酸酯中间体化合物的方法及其在生产5,7-二羟基-6-(2,4,6-三氟苯基)[1,2,4]三唑并[1,5-a]嘧啶中的用途
AU2006329849A1 (en) * 2005-12-16 2007-07-05 Wyeth Lyophilized compositions of a triazolopyrimidine compound
JP2009519954A (ja) * 2005-12-16 2009-05-21 ワイス 抗癌剤として有用な６−［（置換）フェニル］トリアゾロピリミジンの二量体および付加物
CN101600350A (zh) * 2007-01-08 2009-12-09 巴斯夫欧洲公司 唑并嘧啶在防治植物病原性有害真菌中的用途
EP3219207A1 (en) * 2012-09-19 2017-09-20 The Trustees Of The University Of Pennsylvania Heterocyclic compounds and their use for the treatment of neurodegenerative tauopathies
WO2019169111A1 (en) 2018-03-02 2019-09-06 The Trustees Of The University Of Pennsylvania [1,2,4]triazolo[1,5-a]pyrimidine compounds and use in stabilizing microtubules
US20230167121A1 (en) * 2020-04-14 2023-06-01 The Trustees Of The University Of Pennsylvania Substituted {1,2,4,} triazolo{1,5-a} pyrimidine compounds and use in stabilizing microtubules
CN114369098B (zh) * 2022-01-06 2023-03-10 苏州大学 一种三唑并嘧啶醇类化合物及其制备方法和应用
CN118359616A (zh) * 2023-01-19 2024-07-19 中国科学院上海有机化学研究所 一种作为治疗神经系统疾病和肿瘤的多环化合物

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US5593996A (en) * 1991-12-30 1997-01-14 American Cyanamid Company Triazolopyrimidine derivatives
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IL108747A (en) * 1993-03-04 1999-03-12 Shell Int Research Mushroom-killing preparations containing a history of 6 metamorphoses of 5 - 7 Dihalo - 1, 2 - 4 Triazlo [A-1,5] Pyrimidine Certain such new compounds and their preparation
IL108731A (en) * 1993-03-04 1997-03-18 Shell Int Research 6, N-DISUBSTITUTED-£1, 2, 4| TRIAZOLO-£1, 5-a| PYRIMIDINE- 7-AMINE DERIVATIVES, THEIR PREPARATION AND THEIR USE AS FUNGICIDES
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US6559151B2 (en) * 2000-05-08 2003-05-06 Basf Aktiengesellschaft 6-(2-trifluoromethyl-phenyl)-triazolopyrimidines
NZ523807A (en) * 2000-06-30 2004-09-24 Wyeth Corp Substituted-triazolopyrimidines as anticancer agents
SK3522003A3 (en) * 2000-08-25 2003-08-05 Basf Ag Fungicidal formulation
US6459602B1 (en) * 2000-10-26 2002-10-01 O2 Micro International Limited DC-to-DC converter with improved transient response
JP2004513170A (ja) 2000-11-13 2004-04-30 ビーエーエスエフ　アクチェンゲゼルシャフト ７−（ｒ）−アミノトリアゾロピリミジン類、それらの製造及び植物病原性真菌を防除するためのそれらの使用
PT1341794E (pt) 2000-12-06 2004-11-30 Wyeth Corp 6-(trifluorometil-fenil)-triazolopirimidinas fungicidas
DE10063115A1 (de) 2000-12-18 2002-06-27 Bayer Ag Triazolopyrimidine
WO2002067679A1 (en) 2001-02-19 2002-09-06 Basf Aktiengesellschaft Fungicidal mixtures
US7105664B2 (en) 2001-04-11 2006-09-12 Basf Aktiengesellschaft 5-Halogen-6-phenyl-7-fluoroalkylamino-triazolopyrimidines as fungicides
DE10124208A1 (de) * 2001-05-18 2002-11-21 Bayer Ag Verwendung von Triazolopyrimidin-Derivaten als Mikrobizide
EP1412356A1 (en) 2001-07-18 2004-04-28 Basf Aktiengesellschaft Substituted 6-(2-methoxyphenyl)triazolopyrimidines as fungicides
ES2279452T3 (es) 2003-09-24 2007-08-16 Wyeth Holdings Corporation 6-((sustituido)fenil)triazolopirimidinas como agentes antineoplasicos.

Also Published As

Publication number Publication date
DE602004004295D1 (de) 2007-02-22
CN100519559C (zh) 2009-07-29
HK1090374A1 (en) 2006-12-22
SI1680425T1 (sl) 2007-04-30
PT1680425E (pt) 2007-02-28
JP2007506744A (ja) 2007-03-22
PE20050433A1 (es) 2005-07-21
IL174281A0 (en) 2006-08-01
GT200400190A (es) 2005-05-02
PA8613301A1 (es) 2005-11-25
EP1680425B1 (en) 2007-01-10
TW200512211A (en) 2005-04-01
MXPA06003206A (es) 2006-06-23
DK1680425T3 (da) 2007-03-19
US20050090508A1 (en) 2005-04-28
CA2539252A1 (en) 2005-04-07
BRPI0414700A (pt) 2006-11-14
NO20061318L (no) 2006-04-21
DE602004004295T8 (de) 2007-09-20
PL1680425T3 (pl) 2007-05-31
SA04250302A (ar) 2005-12-03
AR045810A1 (es) 2005-11-16
ZA200602387B (en) 2008-11-26
CO5690598A2 (es) 2006-10-31
CR8288A (es) 2006-10-04
US7507739B2 (en) 2009-03-24
DE602004004295T2 (de) 2007-06-06
EP1680425A1 (en) 2006-07-19
AU2004276240A1 (en) 2005-04-07
KR20060098368A (ko) 2006-09-18
RU2006107579A (ru) 2007-10-27
CN1867569A (zh) 2006-11-22
ES2279452T3 (es) 2007-08-16
WO2005030775A1 (en) 2005-04-07
CY1106392T1 (el) 2011-10-12

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