EA201892075A1 - Комбинации ингибиторов lsd1 для применения для лечения солидных опухолей - Google Patents

Комбинации ингибиторов lsd1 для применения для лечения солидных опухолей

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Publication number
EA201892075A1
EA201892075A1 EA201892075A EA201892075A EA201892075A1 EA 201892075 A1 EA201892075 A1 EA 201892075A1 EA 201892075 A EA201892075 A EA 201892075A EA 201892075 A EA201892075 A EA 201892075A EA 201892075 A1 EA201892075 A1 EA 201892075A1
Authority
EA
Eurasian Patent Office
Prior art keywords
treatment
combination
lsd1 inhibitors
solid tumors
combinations
Prior art date
Application number
EA201892075A
Other languages
English (en)
Russian (ru)
Inventor
Марк Демарио
Уильям Пирсолл
Фиона Мэк
Тамара Маэс
Серена Лунарди
Original Assignee
Оризон Дженомикс, С.А.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Оризон Дженомикс, С.А. filed Critical Оризон Дженомикс, С.А.
Publication of EA201892075A1 publication Critical patent/EA201892075A1/ru

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    • A61K31/16—Amides, e.g. hydroxamic acids
    • A61K31/165—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide
    • A61K31/167—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide having the nitrogen of a carboxamide group directly attached to the aromatic ring, e.g. lidocaine, paracetamol
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  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
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  • Engineering & Computer Science (AREA)
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  • Hematology (AREA)
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  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
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EA201892075A 2016-03-15 2017-03-13 Комбинации ингибиторов lsd1 для применения для лечения солидных опухолей EA201892075A1 (ru)

Applications Claiming Priority (2)

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US201662308529P 2016-03-15 2016-03-15
PCT/EP2017/055784 WO2017157825A1 (en) 2016-03-15 2017-03-13 Combinations of lsd1 inhibitors for use in the treatment of solid tumors

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EA201892075A1 true EA201892075A1 (ru) 2019-04-30

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US (2) US10265279B2 (OSRAM)
EP (1) EP3429571B1 (OSRAM)
JP (2) JP7158023B2 (OSRAM)
KR (2) KR102511024B1 (OSRAM)
CN (2) CN120661674A (OSRAM)
AR (1) AR107871A1 (OSRAM)
AU (2) AU2017233898B2 (OSRAM)
CA (1) CA3017411C (OSRAM)
EA (1) EA201892075A1 (OSRAM)
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EP3090998A1 (en) 2015-05-06 2016-11-09 F. Hoffmann-La Roche AG Solid forms
US11013698B2 (en) * 2016-03-15 2021-05-25 Oryzon Genomics S.A. Combinations of LSD1 inhibitors for the treatment of hematological malignancies
CN120661674A (zh) * 2016-03-15 2025-09-19 奥莱松基因组股份有限公司 用于治疗实体瘤的lsd1抑制剂的组合
SG11201710199PA (en) 2016-06-10 2018-05-30 Oryzon Genomics Sa Methods of treating multiple sclerosis
WO2019083971A1 (en) 2017-10-23 2019-05-02 Children's Medical Center Corporation METHODS OF TREATING CANCER USING LSD1 INHIBITORS IN COMBINATION WITH IMMUNOTHERAPY
SG11202003427XA (en) 2017-11-06 2020-05-28 Juno Therapeutics Inc Combination of a cell therapy and a gamma secretase inhibitor
US11597933B2 (en) 2017-11-29 2023-03-07 The Trustees Of Columbia University In The City Of New York Combination therapy of lymphoma
AU2019264231A1 (en) * 2018-05-04 2020-10-22 Oryzon Genomics, S.A. Stable pharmaceutical formulation
KR20210005714A (ko) * 2018-05-06 2021-01-14 아얄라 파마큐티컬즈 아이엔씨. 비스플루오로알킬-1,4-벤조디아제피논 화합물을 포함하는 조합 조성물 및 이의 사용 방법
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