EA201600478A1 - Новые индазолкарбоксамиды, способы их получения, содержащие их фармацевтические препараты и их применение для изготовления лекарственных средств - Google Patents

Новые индазолкарбоксамиды, способы их получения, содержащие их фармацевтические препараты и их применение для изготовления лекарственных средств

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Publication number
EA201600478A1
EA201600478A1 EA201600478A EA201600478A EA201600478A1 EA 201600478 A1 EA201600478 A1 EA 201600478A1 EA 201600478 A EA201600478 A EA 201600478A EA 201600478 A EA201600478 A EA 201600478A EA 201600478 A1 EA201600478 A1 EA 201600478A1
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EA
Eurasian Patent Office
Prior art keywords
production
medicines
new
methods
indazolkarboxamides
Prior art date
Application number
EA201600478A
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English (en)
Other versions
EA032621B1 (ru
Inventor
Ульрих Боте
Хольгер Зибенайхер
Никоул Шмидт
Андреа Ротгери
Ульф Бёмер
Свен Ринг
Хорст Ирльбахер
Юдит Гюнтер
Хольгер Штойбер
Мартин Ланге
Мартина Шефер
Original Assignee
Байер Фарма Акциенгезельшафт
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Publication of EA201600478A1 publication Critical patent/EA201600478A1/ru
Publication of EA032621B1 publication Critical patent/EA032621B1/ru

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    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/4427—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
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    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
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  • Plural Heterocyclic Compounds (AREA)
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Abstract

Настоящая заявка относится к новым 6-замещенным индазолам, содержащим карбоксамидную боковую цепь, к способам их получения, к их применению отдельно или в комбинации для лечения и/или профилактики заболеваний и к их применению для изготовления лекарственных средств для лечения и/или профилактики заболеваний, в частности для лечения и/или профилактики эндометриоза, лимфом, дегенерации желтого пятна, ХОЗЛ и псориаза.
EA201600478A 2013-12-19 2014-12-16 Индазолкарбоксамиды, способы их получения, содержащие их фармацевтические препараты и их применение для изготовления лекарственных средств EA032621B1 (ru)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP13198463 2013-12-19
EP14189216 2014-10-16
PCT/EP2014/077877 WO2015091426A1 (de) 2013-12-19 2014-12-16 Neue indazolcarboxamide, verfahren zu ihrer herstellung, pharmazeutische präparate die diese enthalten, sowie deren verwendung zur herstellung von arzneimitteln

Publications (2)

Publication Number Publication Date
EA201600478A1 true EA201600478A1 (ru) 2016-11-30
EA032621B1 EA032621B1 (ru) 2019-06-28

Family

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EA201600478A EA032621B1 (ru) 2013-12-19 2014-12-16 Индазолкарбоксамиды, способы их получения, содержащие их фармацевтические препараты и их применение для изготовления лекарственных средств

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US (1) US9951086B2 (ru)
EP (1) EP3083586B1 (ru)
JP (1) JP6530406B2 (ru)
KR (1) KR20160094381A (ru)
CN (1) CN106170486B (ru)
AP (1) AP2016009273A0 (ru)
AU (1) AU2014364744B2 (ru)
BR (1) BR112016013632B1 (ru)
CA (1) CA2934137C (ru)
CL (1) CL2016001579A1 (ru)
CR (1) CR20160278A (ru)
CU (1) CU20160087A7 (ru)
CY (1) CY1120437T1 (ru)
DK (1) DK3083586T3 (ru)
DO (1) DOP2016000150A (ru)
EA (1) EA032621B1 (ru)
ES (1) ES2677996T3 (ru)
HR (1) HRP20181107T1 (ru)
HU (1) HUE038367T2 (ru)
IL (1) IL246032B (ru)
JO (1) JO3460B1 (ru)
LT (1) LT3083586T (ru)
MX (1) MX368413B (ru)
PE (1) PE20160900A1 (ru)
PH (1) PH12016501188A1 (ru)
PL (1) PL3083586T3 (ru)
PT (1) PT3083586T (ru)
RS (1) RS57423B1 (ru)
SG (1) SG11201604685RA (ru)
SI (1) SI3083586T1 (ru)
TW (1) TWI667233B (ru)
UA (1) UA117392C2 (ru)
UY (1) UY35907A (ru)
WO (1) WO2015091426A1 (ru)

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JP2017505337A (ja) 2014-01-10 2017-02-16 アウリジーン ディスカバリー テクノロジーズ リミテッド Ｉｒａｋ４阻害剤としてのインダゾール化合物
KR102392684B1 (ko) 2014-01-13 2022-04-29 오리진 디스커버리 테크놀로지스 리미티드 Irak4 억제제로서의 바이시클릭 헤테로시클릴 유도체
JO3705B1 (ar) 2014-11-26 2021-01-31 Bayer Pharma AG إندازولات مستبدلة جديدة، عمليات لتحضيرها، مستحضرات دوائية تحتوي عليها واستخدامها في إنتاج أدوية
EP3195865A1 (de) 2016-01-25 2017-07-26 Bayer Pharma Aktiengesellschaft Kombinationen von irak4 inhibitoren und btk inhibitoren
EP3288558B1 (en) 2015-04-30 2022-05-11 Bayer Pharma Aktiengesellschaft Combinations of inhibitors of irak4 with inhibitors of btk
WO2017023941A1 (en) * 2015-08-04 2017-02-09 Rigel Pharmaceuticals, Inc. Benzazole compounds and methods for making and using the compounds
WO2017108744A1 (de) * 2015-12-22 2017-06-29 Bayer Pharma Aktiengesellschaft Neue substituierte indazole, verfahren zu ihrer herstellung, pharmazeutische präparate die diese enthalten, sowie deren verwendung zur herstellung von arzneimitteln
CA3016364A1 (en) * 2016-03-03 2017-09-08 Bayer Pharma Aktiengesellschaft New 2-substituted indazoles, methods for producing same, pharmaceutical preparations that contain same, and use of same to produce drugs
EP3219329A1 (en) * 2016-03-17 2017-09-20 Bayer Pharma Aktiengesellschaft Combinations of copanlisib
SI3448846T1 (sl) * 2016-04-29 2021-09-30 Bayer Pharma Aktiengesellschaft Sinteza indazolov
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