EA201291099A1 - Новые иммуномодуляторные и противовоспалительные соединения - Google Patents

Новые иммуномодуляторные и противовоспалительные соединения

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Publication number
EA201291099A1
EA201291099A1 EA201291099A EA201291099A EA201291099A1 EA 201291099 A1 EA201291099 A1 EA 201291099A1 EA 201291099 A EA201291099 A EA 201291099A EA 201291099 A EA201291099 A EA 201291099A EA 201291099 A1 EA201291099 A1 EA 201291099A1
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EA
Eurasian Patent Office
Prior art keywords
immunodulator
inflammatory
connections
new
methods
Prior art date
Application number
EA201291099A
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English (en)
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EA024702B1 (ru
EA024702B8 (ru
Inventor
Мейяппан Мутуппаланиаппан
Прашнант Кашинат Бхавар
Срикант Висванадха
Сваруп Кумар В.С. Ваккаланка
Гаятри Сваруп Мерикапуди
Original Assignee
Инкозен Терапьютикс Пвт. Лтд.
Ризен Фармасьютикалз С.А.
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Application filed by Инкозен Терапьютикс Пвт. Лтд., Ризен Фармасьютикалз С.А. filed Critical Инкозен Терапьютикс Пвт. Лтд.
Publication of EA201291099A1 publication Critical patent/EA201291099A1/ru
Publication of EA024702B1 publication Critical patent/EA024702B1/ru
Publication of EA024702B8 publication Critical patent/EA024702B8/ru

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    • C07C235/42—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms having carbon atoms of carboxamide groups bound to carbon atoms of six-membered aromatic rings and singly-bound oxygen atoms bound to the same carbon skeleton
    • C07C235/44—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms having carbon atoms of carboxamide groups bound to carbon atoms of six-membered aromatic rings and singly-bound oxygen atoms bound to the same carbon skeleton with carbon atoms of carboxamide groups and singly-bound oxygen atoms bound to carbon atoms of the same non-condensed six-membered aromatic ring
    • C07C235/56—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms having carbon atoms of carboxamide groups bound to carbon atoms of six-membered aromatic rings and singly-bound oxygen atoms bound to the same carbon skeleton with carbon atoms of carboxamide groups and singly-bound oxygen atoms bound to carbon atoms of the same non-condensed six-membered aromatic ring having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a six-membered aromatic ring
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    • A61K31/167—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide having the nitrogen of a carboxamide group directly attached to the aromatic ring, e.g. lidocaine, paracetamol
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Abstract

Изобретение представляет ингибиторы дигидрооротатдегидрогеназы формулы (I), способы их получения, содержащие их фармацевтические композиции и способы лечения, предупреждения и/или уменьшения интенсивности заболеваний или расстройств, где, как известно, ингибирование дигидрооротатдегидрогеназы дает благоприятный эффект.
EA201291099A 2010-05-06 2011-05-06 Новые иммуномодуляторные и противовоспалительные соединения EA024702B8 (ru)

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