EA201101312A1 - Получение адипиновой кислоты - Google Patents

Получение адипиновой кислоты

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Publication number
EA201101312A1
EA201101312A1 EA201101312A EA201101312A EA201101312A1 EA 201101312 A1 EA201101312 A1 EA 201101312A1 EA 201101312 A EA201101312 A EA 201101312A EA 201101312 A EA201101312 A EA 201101312A EA 201101312 A1 EA201101312 A1 EA 201101312A1
Authority
EA
Eurasian Patent Office
Prior art keywords
acid
alpha
heterologous
obtaining
converting
Prior art date
Application number
EA201101312A
Other languages
English (en)
Inventor
Петронелла Катарина Раемакерс-Франкен
Мартин Шюрманн
Аксель Кристоф Трефцер
Стефан Мария Андре Де Вилдеман
Original Assignee
ДСМ АйПи АССЕТС Б.В.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by ДСМ АйПи АССЕТС Б.В. filed Critical ДСМ АйПи АССЕТС Б.В.
Publication of EA201101312A1 publication Critical patent/EA201101312A1/ru

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    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P7/00—Preparation of oxygen-containing organic compounds
    • C12P7/40—Preparation of oxygen-containing organic compounds containing a carboxyl group including Peroxycarboxylic acids
    • C12P7/44—Polycarboxylic acids
    • C12P7/50—Polycarboxylic acids having keto groups, e.g. 2-ketoglutaric acid
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/0004—Oxidoreductases (1.)
    • C12N9/0008—Oxidoreductases (1.) acting on the aldehyde or oxo group of donors (1.2)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/10—Transferases (2.)
    • C12N9/1025—Acyltransferases (2.3)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/88—Lyases (4.)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P13/00—Preparation of nitrogen-containing organic compounds
    • C12P13/005—Amino acids other than alpha- or beta amino acids, e.g. gamma amino acids
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P13/00—Preparation of nitrogen-containing organic compounds
    • C12P13/02—Amides, e.g. chloramphenicol or polyamides; Imides or polyimides; Urethanes, i.e. compounds comprising N-C=O structural element or polyurethanes
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P17/00—Preparation of heterocyclic carbon compounds with only O, N, S, Se or Te as ring hetero atoms
    • C12P17/10—Nitrogen as only ring hetero atom
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P7/00—Preparation of oxygen-containing organic compounds
    • C12P7/40—Preparation of oxygen-containing organic compounds containing a carboxyl group including Peroxycarboxylic acids
    • C12P7/44—Polycarboxylic acids

Abstract

Изобретение касается способа получения адипиновой кислоты, включающего превращение альфа-кетоглутаровой кислота (AKG) в альфа-кетоадипиновую кислоту (AKA), превращение альфа-кетоадипиновой кислоты в альфа-кетопимелиновую кислоту (AKP), превращение альфа-кетопимелиновой кислоты в 5-формилпентановую кислоту (5-FVA) и превращение 5-формилпентановой кислоты в адипиновую кислоту, причем по меньшей мере одно из этих превращений осуществляется с помощью гетерологичного биокатализатора. Изобретение также касается гетерологичных клеток, содержащих одну или несколько гетерологичных последовательностей нуклеиновой кислоты, кодирующих один или несколько гетерологичных ферментов, способных катализировать по меньшей мере одну стадию реакции в данном способе.
EA201101312A 2009-03-11 2010-03-11 Получение адипиновой кислоты EA201101312A1 (ru)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
EP09154840 2009-03-11
EP09170092 2009-09-11
EP09180441 2009-12-22
PCT/NL2010/050127 WO2010104391A2 (en) 2009-03-11 2010-03-11 Preparation of adipic acid

Publications (1)

Publication Number Publication Date
EA201101312A1 true EA201101312A1 (ru) 2012-03-30

Family

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Family Applications (2)

Application Number Title Priority Date Filing Date
EA201101312A EA201101312A1 (ru) 2009-03-11 2010-03-11 Получение адипиновой кислоты
EA201101311A EA201101311A1 (ru) 2009-03-11 2010-03-11 Получение альфа-кетопимелиновой кислоты

Family Applications After (1)

Application Number Title Priority Date Filing Date
EA201101311A EA201101311A1 (ru) 2009-03-11 2010-03-11 Получение альфа-кетопимелиновой кислоты

Country Status (9)

Country Link
US (2) US20120156737A1 (ru)
EP (2) EP2406385A2 (ru)
JP (2) JP2012520070A (ru)
CN (2) CN102348805A (ru)
AU (2) AU2010221863A1 (ru)
BR (2) BRPI1009192A2 (ru)
EA (2) EA201101312A1 (ru)
TW (1) TW201037078A (ru)
WO (2) WO2010104391A2 (ru)

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Also Published As

Publication number Publication date
WO2010104391A2 (en) 2010-09-16
WO2010104390A3 (en) 2011-04-21
CN102348805A (zh) 2012-02-08
TW201037078A (en) 2010-10-16
US20120028320A1 (en) 2012-02-02
EP2406385A2 (en) 2012-01-18
JP2012520069A (ja) 2012-09-06
AU2010221863A1 (en) 2011-10-06
EA201101311A1 (ru) 2012-04-30
US20120156737A1 (en) 2012-06-21
JP2012520070A (ja) 2012-09-06
CN102892893A (zh) 2013-01-23
BRPI1009197A2 (pt) 2015-09-15
EP2406384A2 (en) 2012-01-18
WO2010104391A3 (en) 2011-06-30
AU2010221862A1 (en) 2011-10-06
WO2010104390A2 (en) 2010-09-16
BRPI1009192A2 (pt) 2015-09-22

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