EA199900046A2 - Таблетки мезилата тровафлоксацина - Google Patents

Таблетки мезилата тровафлоксацина

Info

Publication number
EA199900046A2
EA199900046A2 EA199900046A EA199900046A EA199900046A2 EA 199900046 A2 EA199900046 A2 EA 199900046A2 EA 199900046 A EA199900046 A EA 199900046A EA 199900046 A EA199900046 A EA 199900046A EA 199900046 A2 EA199900046 A2 EA 199900046A2
Authority
EA
Eurasian Patent Office
Prior art keywords
variants
composition
trovafloxacin mesylate
compositions
diluent
Prior art date
Application number
EA199900046A
Other languages
English (en)
Other versions
EA199900046A3 (ru
EA003247B1 (ru
Inventor
Элтон Дейл Джонсон
Кристофер Майкл Синко
Original Assignee
Пфайзер Продактс Инк.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Пфайзер Продактс Инк. filed Critical Пфайзер Продактс Инк.
Publication of EA199900046A2 publication Critical patent/EA199900046A2/ru
Publication of EA199900046A3 publication Critical patent/EA199900046A3/ru
Publication of EA003247B1 publication Critical patent/EA003247B1/ru

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
    • A61K9/2806—Coating materials
    • A61K9/2833—Organic macromolecular compounds
    • A61K9/286—Polysaccharides, e.g. gums; Cyclodextrin
    • A61K9/2866—Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/4353—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems
    • A61K31/4375—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems the heterocyclic ring system containing a six-membered ring having nitrogen as a ring heteroatom, e.g. quinolizines, naphthyridines, berberine, vincamine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2022—Organic macromolecular compounds
    • A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
    • A61K9/2054—Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

Abstract

Композиции, особенно в форме таблеток, содержащие форму Полиморф II мезилата тровафлоксацина, смазывающее вещество и микрокристаллическую целлюлозу (МЦ) в качестве разбавителя. Такие композиции с использованием МЦ в качестве разбавителя показывают хорошие свойства стабильности при хранении и растворения.
EA199900046A 1998-01-21 1999-01-21 Композиция, содержащая мезилат тровафлоксацина (варианты) EA003247B1 (ru)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US7201398P 1998-01-21 1998-01-21

Publications (3)

Publication Number Publication Date
EA199900046A2 true EA199900046A2 (ru) 1999-08-26
EA199900046A3 EA199900046A3 (ru) 1999-12-29
EA003247B1 EA003247B1 (ru) 2003-02-27

Family

ID=22105016

Family Applications (1)

Application Number Title Priority Date Filing Date
EA199900046A EA003247B1 (ru) 1998-01-21 1999-01-21 Композиция, содержащая мезилат тровафлоксацина (варианты)

Country Status (34)

Country Link
US (1) US6187341B1 (ru)
EP (1) EP0930068A3 (ru)
JP (1) JPH11269072A (ru)
KR (1) KR100314977B1 (ru)
CN (1) CN1227743A (ru)
AP (1) AP1094A (ru)
AR (1) AR012780A1 (ru)
AU (1) AU758381B2 (ru)
BG (1) BG103106A (ru)
BR (1) BR9900116A (ru)
CA (1) CA2259698C (ru)
CO (1) CO4810225A1 (ru)
DZ (1) DZ2712A1 (ru)
EA (1) EA003247B1 (ru)
GT (1) GT199900004A (ru)
HR (1) HRP990023A2 (ru)
HU (1) HUP9900154A3 (ru)
ID (1) ID23735A (ru)
IL (1) IL128051A0 (ru)
IS (1) IS4947A (ru)
MA (1) MA24747A1 (ru)
NO (1) NO990243L (ru)
NZ (1) NZ333838A (ru)
OA (1) OA10958A (ru)
PA (1) PA8466701A1 (ru)
PE (1) PE20000169A1 (ru)
PL (1) PL330981A1 (ru)
SG (1) SG70666A1 (ru)
SK (1) SK4299A3 (ru)
TN (1) TNSN99007A1 (ru)
TR (1) TR199900089A3 (ru)
TW (1) TW518224B (ru)
YU (1) YU2399A (ru)
ZA (1) ZA99393B (ru)

Families Citing this family (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CZ292069B6 (cs) * 1998-11-10 2003-07-16 Bayer Aktiengesellschaft Farmaceutický přípravek zahrnující moxifloxacin, způsob výroby a použití tohoto přípravku
KR20020032611A (ko) * 1999-09-20 2002-05-03 스톤 스티븐 에프. 약물의 다형성 전환을 경감시키기 위한 공정
AR025976A1 (es) * 1999-10-08 2002-12-26 Affinium Pharm Inc Inhibidores de fab i.
FR2808441B1 (fr) * 2000-05-04 2004-06-18 Oreal Utilisation de fibres dans une composition de soin ou de maquillage pour matifier la peau
DE10031043A1 (de) * 2000-06-26 2002-02-14 Bayer Ag Retardzubereitungen von Chinolonantibiotika und Verfahren zu ihrer Herstellung
DE60230934D1 (de) * 2001-04-06 2009-03-05 Affinium Pharm Inc Fab-i-inhibitoren
EP1396263A1 (en) 2002-08-09 2004-03-10 Warner-Lambert Company Film coating for tablets and caplets
DK1575951T3 (da) 2002-12-06 2014-09-15 Debiopharm Int Sa Heterocykliske forbindelser, fremgangsmåder til fremstilling deraf og deres anvendelse i terapi
CN100415284C (zh) * 2002-12-30 2008-09-03 毛友昌 六味木香片的制备方法
JP4880448B2 (ja) 2003-03-17 2012-02-22 アフィナム ファーマシューティカルズ，インコーポレーテッド 複数の抗生物質を含む組成物、及びそれを用いる方法
ES2297067T3 (es) * 2003-03-19 2008-05-01 The Jordanian Pharmaceutical Manufacturing Co. Ltd. Composiciones farmaceuticas no higroscopicas que contienen acidos quinolinacarboxilicos de hidratados.
US8906413B2 (en) * 2003-05-12 2014-12-09 Supernus Pharmaceuticals, Inc. Drug formulations having reduced abuse potential
CA2531637A1 (en) * 2003-07-23 2005-02-03 L. Perrigo Company Cellulosic fiber containing composition
CA2568914C (en) 2004-06-04 2013-09-24 Affinium Pharmaceuticals, Inc. Therapeutic agents, and methods of making and using the same
EP1809259B1 (en) * 2004-10-15 2014-12-03 Supernus Pharmaceuticals, Inc. Less abusable pharmaceutical preparations
KR20080075027A (ko) * 2005-12-05 2008-08-13 아피늄 파마슈티컬스, 인크. Ｆａｂｉ 억제제 및 항박테리아제로서의헤테로시클릴아크릴아미드 화합물
JP5468899B2 (ja) 2006-07-20 2014-04-09 アフィニウム ファーマシューティカルズ， インク． Ｆａｂｉインヒビターとしてのアクリルアミド誘導体
US8263613B2 (en) * 2007-02-16 2012-09-11 Affinium Pharmaceuticals, Inc. Salts, prodrugs and polymorphs of fab I inhibitors
EP2861608B8 (en) 2012-06-19 2019-06-19 Debiopharm International SA Prodrug derivatives of (e)-n-methyl-n-((3-methylbenzofuran-2-yl)methyl)-3-(7-oxo-5,6,7,8-tetrahydro-1,8-naphthyridin-3-yl)acrylamide
JP6998881B2 (ja) 2016-02-26 2022-02-10 デビオファーム・インターナショナル・エス・アー 糖尿病性足感染症の処置のための医薬

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5286754A (en) 1986-01-21 1994-02-15 Bayer Aktiengesellschaft Pharmaceutical formulations of ciprofloxacin
DE3601566A1 (de) * 1986-01-21 1987-07-23 Bayer Ag Pharmazeutische zubereitungen von ciprofloxacin
US4957554A (en) 1989-08-16 1990-09-18 Minnesota Mining And Manufacturing Company Dimensionally-controlled ceramics
DE4120646A1 (de) 1991-06-22 1992-12-24 Bayer Ag 7-isoindolinyl-chinolon- und naphthyridoncarbonsaeure-derivate
PL325170A1 (en) * 1995-08-29 1998-07-06 Pfizer Bipolar forms of throwaflocacin

Also Published As

Publication number Publication date
KR19990068014A (ko) 1999-08-25
EP0930068A2 (en) 1999-07-21
CA2259698C (en) 2003-04-15
YU2399A (sh) 2002-06-19
NO990243L (no) 1999-07-22
CO4810225A1 (es) 1999-06-30
BR9900116A (pt) 2000-05-02
TR199900089A2 (xx) 1999-10-21
CN1227743A (zh) 1999-09-08
CA2259698A1 (en) 1999-07-21
IL128051A0 (en) 1999-11-30
IS4947A (is) 1999-07-22
HRP990023A2 (en) 1999-08-31
PL330981A1 (en) 1999-08-02
EP0930068A3 (en) 1999-12-22
TW518224B (en) 2003-01-21
ID23735A (id) 2000-05-11
BG103106A (en) 1999-08-31
AR012780A1 (es) 2000-11-08
DZ2712A1 (fr) 2003-09-01
TNSN99007A1 (fr) 2005-11-10
EA199900046A3 (ru) 1999-12-29
HUP9900154A3 (en) 2000-12-28
OA10958A (en) 2001-10-31
PE20000169A1 (es) 2000-03-10
MA24747A1 (fr) 1999-10-01
SG70666A1 (en) 2000-02-22
NO990243D0 (no) 1999-01-20
TR199900089A3 (tr) 1999-10-21
GT199900004A (es) 2000-07-08
PA8466701A1 (es) 2000-09-29
HUP9900154A2 (hu) 1999-09-28
AP9901443A0 (en) 1999-03-31
AU1217399A (en) 1999-08-12
AU758381B2 (en) 2003-03-20
NZ333838A (en) 2000-03-27
AP1094A (en) 2002-08-19
HU9900154D0 (en) 1999-03-29
ZA99393B (en) 2000-07-21
SK4299A3 (en) 2000-06-12
KR100314977B1 (ko) 2001-11-24
JPH11269072A (ja) 1999-10-05
EA003247B1 (ru) 2003-02-27
US6187341B1 (en) 2001-02-13

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Legal Events

Date Code Title Description
MM4A Lapse of a eurasian patent due to non-payment of renewal fees within the time limit in the following designated state(s)

Designated state(s): AM AZ BY KZ KG MD TJ TM RU