MXPA03001610A - Derivados de acido oxazolil-arilpropionico y su uso como agonistas de los receptores activados por proliferadores de peroxisomas. - Google Patents
Derivados de acido oxazolil-arilpropionico y su uso como agonistas de los receptores activados por proliferadores de peroxisomas.Info
- Publication number
- MXPA03001610A MXPA03001610A MXPA03001610A MXPA03001610A MXPA03001610A MX PA03001610 A MXPA03001610 A MX PA03001610A MX PA03001610 A MXPA03001610 A MX PA03001610A MX PA03001610 A MXPA03001610 A MX PA03001610A MX PA03001610 A MXPA03001610 A MX PA03001610A
- Authority
- MX
- Mexico
- Prior art keywords
- oxazolyl
- acid derivatives
- ppar agonists
- arylpropionic acid
- compounds
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D263/00—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings
- C07D263/02—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings
- C07D263/30—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D263/32—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/06—Antihyperlipidemics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
- C07D413/10—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a carbon chain containing aromatic rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
- C07D413/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing three or more hetero rings
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US22745600P | 2000-08-23 | 2000-08-23 | |
| PCT/US2001/022617 WO2002016332A1 (en) | 2000-08-23 | 2001-08-23 | Oxazolyl-arylpropionic acid derivatives and their use as ppar agonists |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| MXPA03001610A true MXPA03001610A (es) | 2003-09-10 |
Family
ID=22853183
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| MXPA03001610A MXPA03001610A (es) | 2000-08-23 | 2001-08-23 | Derivados de acido oxazolil-arilpropionico y su uso como agonistas de los receptores activados por proliferadores de peroxisomas. |
Country Status (10)
| Country | Link |
|---|---|
| US (1) | US7176224B2 (es) |
| EP (1) | EP1313717B1 (es) |
| JP (1) | JP2004506722A (es) |
| AT (1) | ATE375985T1 (es) |
| AU (1) | AU2001284660A1 (es) |
| CA (1) | CA2418134A1 (es) |
| DE (1) | DE60131001T2 (es) |
| ES (1) | ES2295200T3 (es) |
| MX (1) | MXPA03001610A (es) |
| WO (1) | WO2002016332A1 (es) |
Families Citing this family (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2004506721A (ja) | 2000-08-23 | 2004-03-04 | イーライ・リリー・アンド・カンパニー | オキサゾリル−アリールプロピオン酸誘導体およびそのｐｐａｒアゴニストとしての使用 |
| AU2001284658A1 (en) * | 2000-08-23 | 2002-03-13 | Eli Lilly And Company | Oxazolyl-aryloxyacetic acid derivatives and their use as ppar agonists |
| IL159002A0 (en) * | 2001-06-07 | 2004-05-12 | Lilly Co Eli | Modulators of peroxisome proliferator activated receptors (ppar) |
| NZ529351A (en) * | 2001-06-07 | 2006-01-27 | Lilly Co Eli | Modulators of peroxisome proliferator activated receptors |
| MXPA04003398A (es) * | 2001-10-12 | 2004-11-22 | Nippon Chemiphar Co | Activador para el receptor o activado con el proliferador de peroxisoma. |
| US20050080115A1 (en) * | 2002-10-28 | 2005-04-14 | Lone Jeppesen | Novel compounds, their preparation and use |
| PL210871B1 (pl) | 2002-11-08 | 2012-03-30 | Hoffmann La Roche | Pochodne oksazolu, sposób ich wytwarzania, środki farmaceutyczne i zastosowanie pochodnych oksazolu |
| US7192970B2 (en) * | 2002-11-26 | 2007-03-20 | Chipscreen Biosciences, Ltd. | Noncyclic 1,3-dicarbonyl compounds as dual PPAR agonists with potent antihyperglycemic and antihyperlipidemic activity |
| WO2004073606A2 (en) | 2003-02-14 | 2004-09-02 | Eli Lilly And Company | Sulfonamide derivatives as ppar modulators |
| DE102004060227B3 (de) * | 2004-12-15 | 2006-07-20 | Sanofi-Aventis Deutschland Gmbh | Verfahren zur Herstellung von Oxazolen durch Kondensation von aromatischen Aldehyden mit α-Ketoximen zu N-Oxiden und nachfolgende Reaktion mit aktivierten Säurederivaten |
| EP1911738A4 (en) * | 2005-07-29 | 2009-12-16 | Takeda Pharmaceutical | PHENOXYALKANSÄUREVERBINDUNG |
| TWI464164B (zh) * | 2009-08-05 | 2014-12-11 | Daiichi Sankyo Co Ltd | 醯胺衍生物 |
| CN103249726B (zh) * | 2010-10-14 | 2015-01-07 | 第一三共株式会社 | 酰基苯衍生物 |
Family Cites Families (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5089514A (en) | 1990-06-14 | 1992-02-18 | Pfizer Inc. | 3-coxazolyl [phenyl, chromanyl or benzofuranyl]-2-hydroxypropionic acid derivatives and analogs as hypoglycemic agents |
| US5232945A (en) | 1992-07-20 | 1993-08-03 | Pfizer Inc. | 3-aryl-2-hydroxypropionic acid derivatives and analogs as antihypertensives |
| US5902726A (en) | 1994-12-23 | 1999-05-11 | Glaxo Wellcome Inc. | Activators of the nuclear orphan receptor peroxisome proliferator-activated receptor gamma |
| ES2202582T3 (es) | 1996-02-02 | 2004-04-01 | MERCK & CO., INC. | Agentes antidiabeticos. |
| GB9604242D0 (en) | 1996-02-28 | 1996-05-01 | Glaxo Wellcome Inc | Chemical compounds |
| WO1998007699A1 (fr) | 1996-08-19 | 1998-02-26 | Japan Tobacco Inc. | Derives d'acide propionique et applications de ces derives |
| ATE451346T1 (de) * | 1998-03-10 | 2009-12-15 | Ono Pharmaceutical Co | Carbonsäurederivate und medikamente die diese als aktiven wirkstoff enthalten |
| PT1206457E (pt) | 1999-08-27 | 2004-03-31 | Lilly Co Eli | Derivados de diaril-oxa(tia)zol e seu uso como moduladores dos ppars |
| JP4316787B2 (ja) | 2000-01-11 | 2009-08-19 | 壽製薬株式会社 | エーテル又はアミド誘導体、その製法並びにそれを含有する糖尿病治療剤、 |
| JP2004506721A (ja) * | 2000-08-23 | 2004-03-04 | イーライ・リリー・アンド・カンパニー | オキサゾリル−アリールプロピオン酸誘導体およびそのｐｐａｒアゴニストとしての使用 |
| AU2001284658A1 (en) | 2000-08-23 | 2002-03-13 | Eli Lilly And Company | Oxazolyl-aryloxyacetic acid derivatives and their use as ppar agonists |
-
2001
- 2001-08-23 WO PCT/US2001/022617 patent/WO2002016332A1/en active IP Right Grant
- 2001-08-23 EP EP01963734A patent/EP1313717B1/en not_active Expired - Lifetime
- 2001-08-23 AU AU2001284660A patent/AU2001284660A1/en not_active Abandoned
- 2001-08-23 MX MXPA03001610A patent/MXPA03001610A/es active IP Right Grant
- 2001-08-23 US US10/343,187 patent/US7176224B2/en not_active Expired - Fee Related
- 2001-08-23 JP JP2002521433A patent/JP2004506722A/ja not_active Withdrawn
- 2001-08-23 CA CA002418134A patent/CA2418134A1/en not_active Abandoned
- 2001-08-23 DE DE60131001T patent/DE60131001T2/de not_active Expired - Lifetime
- 2001-08-23 ES ES01963734T patent/ES2295200T3/es not_active Expired - Lifetime
- 2001-08-23 AT AT01963734T patent/ATE375985T1/de not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| AU2001284660A1 (en) | 2002-03-04 |
| EP1313717A1 (en) | 2003-05-28 |
| WO2002016332A1 (en) | 2002-02-28 |
| EP1313717B1 (en) | 2007-10-17 |
| JP2004506722A (ja) | 2004-03-04 |
| ES2295200T3 (es) | 2008-04-16 |
| DE60131001D1 (de) | 2007-11-29 |
| ATE375985T1 (de) | 2007-11-15 |
| CA2418134A1 (en) | 2002-02-28 |
| US20040138277A1 (en) | 2004-07-15 |
| US7176224B2 (en) | 2007-02-13 |
| DE60131001T2 (de) | 2008-07-17 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FG | Grant or registration |