YU26001A - Derivati ureidopiperidina kao selektivni antagonisti ljudskih nk3 receptora - Google Patents

Derivati ureidopiperidina kao selektivni antagonisti ljudskih nk3 receptora

Info

Publication number
YU26001A
YU26001A YU26001A YU26001A YU26001A YU 26001 A YU26001 A YU 26001A YU 26001 A YU26001 A YU 26001A YU 26001 A YU26001 A YU 26001A YU 26001 A YU26001 A YU 26001A
Authority
YU
Yugoslavia
Prior art keywords
receptor antagonists
ureidopiperidine
derivatives
selective human
selective
Prior art date
Application number
YU26001A
Other languages
English (en)
Inventor
Alain Aulombard
Xavier Edmonds-Alt
Vincenzo Proietto
Broeck Didier Van
Original Assignee
Sanofi-Synthelabo
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sanofi-Synthelabo filed Critical Sanofi-Synthelabo
Publication of YU26001A publication Critical patent/YU26001A/sh

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D211/36—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D211/60—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C07D211/62—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals attached in position 4
    • C07D211/64—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals attached in position 4 having an aryl radical as the second substituent in position 4
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/445—Non condensed piperidines, e.g. piperocaine
    • A61K31/451—Non condensed piperidines, e.g. piperocaine having a carbocyclic group directly attached to the heterocyclic ring, e.g. glutethimide, meperidine, loperamide, phencyclidine, piminodine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D211/36—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D211/56—Nitrogen atoms
    • C07D211/58—Nitrogen atoms attached in position 4
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Abstract

Pronalazak se odnosi na jedinjenje formule (I) u racemskom ili optički čistom obliku, postupke za njihovo dobijanje i farmaceutske preparate koji sadrže iste. Pomenuta jedinjenja su selektivni NK3 receptor antagonisti.[The invention concerns compounds of formula (I) in racemic or optically pure form, methods for obtaining them and pharmaceutical compositions containing same. Said compounds are selective NK3 receptor antagonists.
YU26001A 1998-10-09 1999-10-04 Derivati ureidopiperidina kao selektivni antagonisti ljudskih nk3 receptora YU26001A (sh)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR9812859A FR2784377B3 (fr) 1998-10-09 1998-10-09 Nouveaux composes derives d'ureidopiperidine, antagonistes selectifs des recepteurs nk3 humains, procede pour leur obtention et compositions pharmaceutiques les contenant

Publications (1)

Publication Number Publication Date
YU26001A true YU26001A (sh) 2003-04-30

Family

ID=9531536

Family Applications (1)

Application Number Title Priority Date Filing Date
YU26001A YU26001A (sh) 1998-10-09 1999-10-04 Derivati ureidopiperidina kao selektivni antagonisti ljudskih nk3 receptora

Country Status (25)

Country Link
US (1) US6465489B1 (sh)
EP (1) EP1119552A1 (sh)
JP (1) JP2002527423A (sh)
KR (1) KR20010085903A (sh)
CN (1) CN1133622C (sh)
AR (1) AR029148A1 (sh)
AU (1) AU751592B2 (sh)
BR (1) BR9914397A (sh)
CA (1) CA2346729A1 (sh)
CO (1) CO5180555A1 (sh)
DZ (1) DZ2905A1 (sh)
EA (1) EA003613B1 (sh)
EE (1) EE200100214A (sh)
FR (1) FR2784377B3 (sh)
HU (1) HUP0201709A3 (sh)
IL (1) IL142362A0 (sh)
IS (1) IS5897A (sh)
NO (1) NO20011779L (sh)
NZ (1) NZ510779A (sh)
PL (1) PL347910A1 (sh)
SK (1) SK4642001A3 (sh)
TR (1) TR200101030T2 (sh)
TW (1) TW539669B (sh)
WO (1) WO2000021931A1 (sh)
YU (1) YU26001A (sh)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6476050B2 (en) 2000-03-14 2002-11-05 Sepracor, Inc. 3-substituted piperidines comprising urea functionality, and methods of use thereof
US20060128752A1 (en) * 2002-07-03 2006-06-15 Giuseppe Alvaro Chemical compounds
US20110144081A1 (en) 2009-12-15 2011-06-16 Henner Knust Pyrrolidine derivatives
US9554659B2 (en) 2012-10-22 2017-01-31 Uwm Research Foundation, Inc. Infant sleep pod
WO2020101017A1 (ja) * 2018-11-15 2020-05-22 国立大学法人九州大学 Ｉｌ－３１介在性疾患の予防又は治療剤及び医薬組成物

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL99320A (en) 1990-09-05 1995-07-31 Sanofi Sa Arylalkylamines, their preparation and pharmaceutical preparations containing them
FR2676055B1 (fr) 1991-05-03 1993-09-03 Sanofi Elf Composes polycycliques amines et leurs enantiomeres, procede pour leur preparation et compositions pharmaceutiques les contenant.
FR2688219B1 (fr) * 1992-03-03 1994-07-08 Sanofi Elf Sels d'ammonium quaternaires de composes aromatiques amines, leur preparation et compositions pharmaceutiques les contenant.
FR2719311B1 (fr) * 1994-03-18 1998-06-26 Sanofi Sa Composés antagonistes sélectifs du récepteur NK3 humain et leur utilisation comme médicaments et outils de diagnostic.
FR2738819B1 (fr) 1995-09-14 1997-12-05 Sanofi Sa Nouveaux composes antagonistes selectifs du recepteur nk3 humain, procede pour leur obtention et compositions pharmaceutiques les contenant
AU4176997A (en) * 1996-09-16 1998-04-02 Warner-Lambert Company 3-alkyl-3-phenyl-piperidines

Also Published As

Publication number Publication date
TR200101030T2 (tr) 2001-08-21
US6465489B1 (en) 2002-10-15
CN1329594A (zh) 2002-01-02
EP1119552A1 (fr) 2001-08-01
EA003613B1 (ru) 2003-06-26
KR20010085903A (ko) 2001-09-07
NO20011779L (no) 2001-06-07
AU751592B2 (en) 2002-08-22
WO2000021931A1 (fr) 2000-04-20
IS5897A (is) 2001-03-16
HUP0201709A3 (en) 2003-03-28
AU5988799A (en) 2000-05-01
PL347910A1 (en) 2002-04-22
SK4642001A3 (en) 2001-09-11
CA2346729A1 (en) 2000-04-20
IL142362A0 (en) 2002-03-10
DZ2905A1 (fr) 2004-03-01
BR9914397A (pt) 2001-06-26
CN1133622C (zh) 2004-01-07
HUP0201709A2 (en) 2002-09-28
EE200100214A (et) 2002-08-15
CO5180555A1 (es) 2002-07-30
TW539669B (en) 2003-07-01
AR029148A1 (es) 2003-06-18
FR2784377B3 (fr) 2000-11-17
FR2784377A1 (fr) 2000-04-14
NZ510779A (en) 2003-07-25
NO20011779D0 (no) 2001-04-06
JP2002527423A (ja) 2002-08-27
EA200100299A1 (ru) 2001-10-22

Similar Documents

Publication Publication Date Title
IL140622A0 (en) Biphenyl sufonamide derivatives, pharmaceutical compositions containing the same and methods for the preparation thereof
HK1058934A1 (en) Cyclopentanoindoles, compositions containing such compounds and methods of treatment
NO20034230D0 (no) 1,2,3,4-tetrahydroisokinolin-derivater som urotensin II reseptor-antagonister
IL155806A0 (en) Novel benzazepines and related heterocyclic derivatives which are useful as orexin receptor antagonists
PT1274687E (pt) Derivados de 1,2,3,4-tetra-hidroisoquinolina
MY134559A (en) Lactam compound to inhibit beta-amyloid peptide release or synthesis
HUP0103913A3 (en) Novel form of irbesartan, methods for obtaining said form and pharmaceutical compositions containing same
HUP0103567A3 (en) 2-substituted-1-piperidyl benzimidazole compounds as orl1-receptor agonists, process for their preparation and pharmaceutical compositions containing the same
YU80902A (sh) Novi indolin-2-on derivati, njihovo dobijanje i farmaceuski oblici koji ih sadrže
CL2003001814A1 (es) Compuestos derivados de 1,3,8-triazaespiro[4,5]decan-4-ona jidroxialquil sustituidos, moduladores del receptor orl-1; compuestos intermediarios; composicion farmaceutica que contiene dichos compuestos; procedimiento de preparacion de la composicion f
HRP20020330B1 (sh)
IL143670A0 (en) Methods for the expression of active protein-immunoglobulin fusions, active protein-immunoglobulin fusions obtained thereby and pharmaceutical compositions containing the same
UA66865C2 (uk) Інденопіролокарбазоли, фармацевтична композиція, спосіб інгібування кіназної активності та спосіб лікування (варіанти)
ZA200201788B (en) Substituted 1,5-dihydropyrrol-2-on derivatives as NMDA receptor antagonists for the treatment of pain.
YU13301A (sh) Muskarinski agonisti i antagonisti
DE69229339T2 (de) Kristallines tiagabinehydrochlorid-monohydrat, seine herstellung und verwendung
SE9802937D0 (sv) Novel compounds
YU26001A (sh) Derivati ureidopiperidina kao selektivni antagonisti ljudskih nk3 receptora
NO20002408D0 (no) 5-HT1F antagonister
EP0778833A4 (en) ENDOTHELIN RECEPTOR ANTAGONISTS
SE9803107D0 (sv) Novel Compunds
TWI231815B (en) Glycopeptide derivatives and pharmaceutical compositions containing the same for use as antibacterial agents