EA024042B1 - Способ снижения внутриглазного давления у людей - Google Patents
Способ снижения внутриглазного давления у людей Download PDFInfo
- Publication number
- EA024042B1 EA024042B1 EA201171339A EA201171339A EA024042B1 EA 024042 B1 EA024042 B1 EA 024042B1 EA 201171339 A EA201171339 A EA 201171339A EA 201171339 A EA201171339 A EA 201171339A EA 024042 B1 EA024042 B1 EA 024042B1
- Authority
- EA
- Eurasian Patent Office
- Prior art keywords
- compound
- iop
- eye
- hours
- treatment
- Prior art date
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- C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
- C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
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| PCT/US2010/033112 WO2010127210A1 (en) | 2009-05-01 | 2010-04-30 | Method of reducing intraocular pressure in humans |
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| EA201171339A1 EA201171339A1 (ru) | 2012-05-30 |
| EA024042B1 true EA024042B1 (ru) | 2016-08-31 |
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| EA201171339A EA024042B1 (ru) | 2009-05-01 | 2010-04-30 | Способ снижения внутриглазного давления у людей |
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Families Citing this family (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE102008062567A1 (de) | 2008-12-16 | 2010-06-17 | Bayer Schering Pharma Aktiengesellschaft | Dipeptoid-Prodrugs und ihre Verwendung |
| DE102009006602A1 (de) * | 2009-01-29 | 2010-08-05 | Bayer Schering Pharma Aktiengesellschaft | Alkylamino-substituierte Dicyanopyridine und deren Aminosäureester-Prodrugs |
| KR20120091049A (ko) * | 2009-10-26 | 2012-08-17 | 이노텍 파마슈티컬스 코포레이션 | 안과용 제제 및 이의 제조 방법 |
| JP2013516495A (ja) * | 2010-01-11 | 2013-05-13 | イノテック ファーマシューティカルズ コーポレイション | 眼圧を低下させる組合せ、キット、および方法 |
| CN102933220A (zh) * | 2010-03-19 | 2013-02-13 | 伊诺泰克制药公司 | 用于降低眼内压的腺苷a1激动剂与碳酸酐酶抑制剂的组合型组合物 |
| PT2555776T (pt) * | 2010-03-19 | 2017-02-01 | Inotek Pharmaceuticals Corp | Composições de combinação de agonistas de adenosina a1 e bloqueadores não selectivos dos receptores adrenérgicos beta para redução da pressão intra-ocular |
| JP2013523739A (ja) | 2010-03-26 | 2013-06-17 | イノテック ファーマシューティカルズ コーポレイション | Ｎ６−シクロペンチルアデノシン（ｃｐａ）、ｃｐａ誘導体またはそれらのプロドラッグを用いてヒトにおける眼内圧を低下させる方法 |
| DE102010030688A1 (de) | 2010-06-30 | 2012-01-05 | Bayer Schering Pharma Aktiengesellschaft | Substituierte Dicyanopyridine und ihre Verwendung |
| US20120058983A1 (en) * | 2010-09-02 | 2012-03-08 | Bayer Pharma Aktiengesellschaft | Adenosine A1 agonists for the treatment of glaucoma and ocular hypertension |
| SMT201700377T1 (it) * | 2012-01-26 | 2017-09-07 | Inotek Pharmaceuticals Corp | Polimorfi anidri di (2r,3s,4r,5r)-5-(6-(ciclopentilammino)-9h-purin-9-il)-3,4- diidrossitetraidrofuran-2-il)}metil nitrato e processi di sua preparazione |
| NZ630759A (en) | 2013-03-15 | 2017-07-28 | Inotek Pharmaceuticals Corp | Ophthalmic formulations comprising an a1 agonist |
| KR20170123605A (ko) * | 2014-12-03 | 2017-11-08 | 이노텍 파마슈티컬스 코포레이션 | 황반 변성의 예방, 완화 또는 치료 방법 |
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| WO2005117910A2 (en) * | 2004-05-26 | 2005-12-15 | Inotek Pharmaceuticals Corporation | Purine derivatives as adenosine a1 receptor agonists and methods of use thereof |
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| CN101010085B (zh) | 2004-05-26 | 2012-12-26 | 伊诺泰克制药公司 | 嘌呤衍生物作为腺苷a1受体激动剂及其用法 |
| BRPI0619261A2 (pt) * | 2005-11-30 | 2011-09-27 | Inotek Pharmaceuticals Corp | derivados de purina e métodos de uso desses |
| KR20120091049A (ko) * | 2009-10-26 | 2012-08-17 | 이노텍 파마슈티컬스 코포레이션 | 안과용 제제 및 이의 제조 방법 |
| JP2013516495A (ja) * | 2010-01-11 | 2013-05-13 | イノテック ファーマシューティカルズ コーポレイション | 眼圧を低下させる組合せ、キット、および方法 |
| CN102933220A (zh) * | 2010-03-19 | 2013-02-13 | 伊诺泰克制药公司 | 用于降低眼内压的腺苷a1激动剂与碳酸酐酶抑制剂的组合型组合物 |
| PT2555776T (pt) * | 2010-03-19 | 2017-02-01 | Inotek Pharmaceuticals Corp | Composições de combinação de agonistas de adenosina a1 e bloqueadores não selectivos dos receptores adrenérgicos beta para redução da pressão intra-ocular |
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| WO2005117910A2 (en) * | 2004-05-26 | 2005-12-15 | Inotek Pharmaceuticals Corporation | Purine derivatives as adenosine a1 receptor agonists and methods of use thereof |
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