SG175346A1 - Method of reducing intraocular pressure in humans - Google Patents
Method of reducing intraocular pressure in humans Download PDFInfo
- Publication number
- SG175346A1 SG175346A1 SG2011078151A SG2011078151A SG175346A1 SG 175346 A1 SG175346 A1 SG 175346A1 SG 2011078151 A SG2011078151 A SG 2011078151A SG 2011078151 A SG2011078151 A SG 2011078151A SG 175346 A1 SG175346 A1 SG 175346A1
- Authority
- SG
- Singapore
- Prior art keywords
- compound
- purin
- dihydroxytetrahydrofuran
- iop
- bicyclic
- Prior art date
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- A61K31/706—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom
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- A61K31/7076—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom containing condensed or non-condensed pyrimidines containing purines, e.g. adenosine, adenylic acid
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- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
- C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
- C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
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Landscapes
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| US17465509P | 2009-05-01 | 2009-05-01 | |
| US21999009P | 2009-06-24 | 2009-06-24 | |
| PCT/US2010/033112 WO2010127210A1 (en) | 2009-05-01 | 2010-04-30 | Method of reducing intraocular pressure in humans |
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| SG175346A1 true SG175346A1 (en) | 2011-11-28 |
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| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| SG2011078151A SG175346A1 (en) | 2009-05-01 | 2010-04-30 | Method of reducing intraocular pressure in humans |
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Families Citing this family (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE102008062567A1 (de) | 2008-12-16 | 2010-06-17 | Bayer Schering Pharma Aktiengesellschaft | Dipeptoid-Prodrugs und ihre Verwendung |
| DE102009006602A1 (de) * | 2009-01-29 | 2010-08-05 | Bayer Schering Pharma Aktiengesellschaft | Alkylamino-substituierte Dicyanopyridine und deren Aminosäureester-Prodrugs |
| CA2774704A1 (en) * | 2009-10-26 | 2011-05-05 | Inotek Pharmaceuticals Corporation | Ophthalmic formulation and method of manufacture thereof |
| EA025415B1 (ru) * | 2010-01-11 | 2016-12-30 | Инотек Фармасьютикалз Корпорейшн | Комбинация, набор и способ снижения внутриглазного давления |
| PT2555775T (pt) * | 2010-03-19 | 2017-02-01 | Inotek Pharmaceuticals Corp | Composições de combinação de agonistas de adenosina a1 e inibidores de anidrase carbónica para redução da pressão intra-ocular |
| LT2555776T (lt) * | 2010-03-19 | 2017-04-25 | Inotek Pharmaceuticals Corporation | Adenozino a1 agonistų ir neselektyvių beta adrenerginių receptorių blokatorių derinio kompozicijos, skirtos akispūdžio mažinimui |
| EP2569325A4 (en) | 2010-03-26 | 2013-10-09 | Inotek Pharmaceuticals Corp | METHOD FOR REDUCING INNER EYE PRESSURE IN HUMANS USING N6-CYCLOPENTYLADENOSINE (CPA), CPA DERIVATIVES OR PRODRUGS THEREOF |
| DE102010030688A1 (de) | 2010-06-30 | 2012-01-05 | Bayer Schering Pharma Aktiengesellschaft | Substituierte Dicyanopyridine und ihre Verwendung |
| US20120058983A1 (en) * | 2010-09-02 | 2012-03-08 | Bayer Pharma Aktiengesellschaft | Adenosine A1 agonists for the treatment of glaucoma and ocular hypertension |
| US9278991B2 (en) * | 2012-01-26 | 2016-03-08 | Inotek Pharmaceuticals Corporation | Anhydrous polymorphs of [(2R,3S,4R,5R)-5-(6-(cyclopentylamino)-9H-purin-9-yl)-3,4-dihydroxytetrahydrofuran-2-yl)} methyl nitrate and processes of preparation thereof |
| CA2903114A1 (en) | 2013-03-15 | 2014-09-25 | Inotek Pharmaceuticals Corporation | Ophthalmic formulations |
| EP3247715A1 (en) * | 2014-12-03 | 2017-11-29 | Inotek Pharmaceuticals Corporation | Methods of preventing, reducing or treating macular degeneration |
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| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101010085B (zh) | 2004-05-26 | 2012-12-26 | 伊诺泰克制药公司 | 嘌呤衍生物作为腺苷a1受体激动剂及其用法 |
| DE602005020286D1 (de) * | 2004-05-26 | 2010-05-12 | Inotek Pharmaceuticals Corp | Purinderivate als adenosin a 1 rezeptoragonisten und anwendungsverfahren dafür |
| AU2006320578B2 (en) * | 2005-11-30 | 2013-01-31 | Inotek Pharmaceuticals Corporation | Purine derivatives and methods of use thereof |
| CA2774704A1 (en) * | 2009-10-26 | 2011-05-05 | Inotek Pharmaceuticals Corporation | Ophthalmic formulation and method of manufacture thereof |
| EA025415B1 (ru) * | 2010-01-11 | 2016-12-30 | Инотек Фармасьютикалз Корпорейшн | Комбинация, набор и способ снижения внутриглазного давления |
| PT2555775T (pt) * | 2010-03-19 | 2017-02-01 | Inotek Pharmaceuticals Corp | Composições de combinação de agonistas de adenosina a1 e inibidores de anidrase carbónica para redução da pressão intra-ocular |
| LT2555776T (lt) * | 2010-03-19 | 2017-04-25 | Inotek Pharmaceuticals Corporation | Adenozino a1 agonistų ir neselektyvių beta adrenerginių receptorių blokatorių derinio kompozicijos, skirtos akispūdžio mažinimui |
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2010
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- 2010-04-30 EP EP10770402.5A patent/EP2424546B1/en active Active
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