SMT201500295B - Procedimento per la riduzione della pressione intraoculare negli umani - Google Patents
Procedimento per la riduzione della pressione intraoculare negli umaniInfo
- Publication number
- SMT201500295B SMT201500295B SM201500295T SM201500295T SMT201500295B SM T201500295 B SMT201500295 B SM T201500295B SM 201500295 T SM201500295 T SM 201500295T SM 201500295 T SM201500295 T SM 201500295T SM T201500295 B SMT201500295 B SM T201500295B
- Authority
- SM
- San Marino
- Prior art keywords
- humans
- procedure
- intraocular pressure
- reducing intraocular
- reducing
- Prior art date
Links
- 230000004410 intraocular pressure Effects 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
- C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
- C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
- C07H19/16—Purine radicals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/7042—Compounds having saccharide radicals and heterocyclic rings
- A61K31/7052—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides
- A61K31/706—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom
- A61K31/7064—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom containing condensed or non-condensed pyrimidines
- A61K31/7076—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom containing condensed or non-condensed pyrimidines containing purines, e.g. adenosine, adenylic acid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/08—Solutions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
- A61P27/06—Antiglaucoma agents or miotics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2121/00—Preparations for use in therapy
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Epidemiology (AREA)
- Molecular Biology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Ophthalmology & Optometry (AREA)
- Biochemistry (AREA)
- Biotechnology (AREA)
- Genetics & Genomics (AREA)
- Nutrition Science (AREA)
- Physiology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Prostheses (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US17465509P | 2009-05-01 | 2009-05-01 | |
| US21999009P | 2009-06-24 | 2009-06-24 | |
| PCT/US2010/033112 WO2010127210A1 (en) | 2009-05-01 | 2010-04-30 | Method of reducing intraocular pressure in humans |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| SMT201500295B true SMT201500295B (it) | 2016-01-08 |
Family
ID=43030847
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| SM201500295T SMT201500295B (it) | 2009-05-01 | 2015-11-30 | Procedimento per la riduzione della pressione intraoculare negli umani |
Country Status (25)
| Country | Link |
|---|---|
| US (2) | US8470800B2 (enExample) |
| EP (1) | EP2424546B1 (enExample) |
| JP (1) | JP5778663B2 (enExample) |
| KR (1) | KR101757940B1 (enExample) |
| CN (1) | CN102413832B (enExample) |
| AU (1) | AU2010242943B2 (enExample) |
| BR (1) | BRPI1009971A2 (enExample) |
| CA (1) | CA2762064A1 (enExample) |
| CL (1) | CL2011002675A1 (enExample) |
| DK (1) | DK2424546T3 (enExample) |
| EA (1) | EA024042B1 (enExample) |
| ES (1) | ES2554684T3 (enExample) |
| HR (1) | HRP20151200T1 (enExample) |
| HU (1) | HUE028068T2 (enExample) |
| IL (1) | IL216081A (enExample) |
| MX (1) | MX2011011229A (enExample) |
| MY (1) | MY159244A (enExample) |
| NZ (1) | NZ596428A (enExample) |
| PL (1) | PL2424546T3 (enExample) |
| PT (1) | PT2424546E (enExample) |
| RS (1) | RS54378B1 (enExample) |
| SG (1) | SG175346A1 (enExample) |
| SI (1) | SI2424546T1 (enExample) |
| SM (1) | SMT201500295B (enExample) |
| WO (1) | WO2010127210A1 (enExample) |
Families Citing this family (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE102008062567A1 (de) | 2008-12-16 | 2010-06-17 | Bayer Schering Pharma Aktiengesellschaft | Dipeptoid-Prodrugs und ihre Verwendung |
| DE102009006602A1 (de) * | 2009-01-29 | 2010-08-05 | Bayer Schering Pharma Aktiengesellschaft | Alkylamino-substituierte Dicyanopyridine und deren Aminosäureester-Prodrugs |
| MX2012004225A (es) * | 2009-10-26 | 2012-06-08 | Inotek Pharmaceuticals Corp | Formulacion oftalmica y metodo de fabricacion de la misma. |
| AU2011203897B2 (en) * | 2010-01-11 | 2016-11-17 | Inotek Pharmaceuticals Corporation | Combination, kit and method of reducing intraocular pressure |
| ME02594B (me) | 2010-03-19 | 2017-06-20 | Inotek Pharmaceuticals Corp | Kombinovane kompozicje adenozinskih a1 agonista i ne-selektivnih beta- adrenergičnih receptor blokera za snižavanje intraokularnog pritiska |
| ES2613254T3 (es) * | 2010-03-19 | 2017-05-23 | Inotek Pharmaceuticals Corporation | Composiciones de combinación de agonistas de adenosina A1 e inhibidores de anhidrasa carbónica para reducir la presión intraocular |
| BR112012023749A2 (pt) | 2010-03-26 | 2016-08-23 | Inotek Pharmaceuticals Corp | método para reduzir a pressão intraocular em humanos utilizando n6-ciclopentiladenosina (cpa), derivados de cpa ou pró-fármacos desses |
| DE102010030688A1 (de) | 2010-06-30 | 2012-01-05 | Bayer Schering Pharma Aktiengesellschaft | Substituierte Dicyanopyridine und ihre Verwendung |
| US20120058983A1 (en) * | 2010-09-02 | 2012-03-08 | Bayer Pharma Aktiengesellschaft | Adenosine A1 agonists for the treatment of glaucoma and ocular hypertension |
| BR112014018413A8 (pt) * | 2012-01-26 | 2017-07-11 | Inotek Pharmaceuticals Corp | Polimorfos anidros de nitrato de metila [(2r,3s,4r,5r)-5-(6-(ciclopentilamino)-9h-purin-9-il)-3,4-diidroxitetraidrofuran-2-il)] e processos de preparação do mesmo |
| EA201591433A1 (ru) | 2013-03-15 | 2015-12-30 | Инотек Фармасьютикалс Корпорейшн | Офтальмологические составы |
| CA2967446A1 (en) * | 2014-12-03 | 2016-06-09 | Inotek Pharmaceuticals Corporation | Methods of preventing, reducing or treating macular degeneration |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103087133B (zh) * | 2004-05-26 | 2016-09-14 | 伊诺泰克制药公司 | 嘌呤衍生物作为腺苷a1受体激动剂及其用法 |
| CN101010085B (zh) | 2004-05-26 | 2012-12-26 | 伊诺泰克制药公司 | 嘌呤衍生物作为腺苷a1受体激动剂及其用法 |
| EP1962597A4 (en) * | 2005-11-30 | 2008-12-17 | Inotek Pharmaceuticals Corp | PURINE DERIVATIVES AND METHOD OF USE |
| MX2012004225A (es) * | 2009-10-26 | 2012-06-08 | Inotek Pharmaceuticals Corp | Formulacion oftalmica y metodo de fabricacion de la misma. |
| AU2011203897B2 (en) * | 2010-01-11 | 2016-11-17 | Inotek Pharmaceuticals Corporation | Combination, kit and method of reducing intraocular pressure |
| ME02594B (me) * | 2010-03-19 | 2017-06-20 | Inotek Pharmaceuticals Corp | Kombinovane kompozicje adenozinskih a1 agonista i ne-selektivnih beta- adrenergičnih receptor blokera za snižavanje intraokularnog pritiska |
| ES2613254T3 (es) * | 2010-03-19 | 2017-05-23 | Inotek Pharmaceuticals Corporation | Composiciones de combinación de agonistas de adenosina A1 e inhibidores de anhidrasa carbónica para reducir la presión intraocular |
-
2010
- 2010-04-30 HR HRP20151200TT patent/HRP20151200T1/hr unknown
- 2010-04-30 NZ NZ596428A patent/NZ596428A/en not_active IP Right Cessation
- 2010-04-30 MY MYPI2011004858A patent/MY159244A/en unknown
- 2010-04-30 PT PT107704025T patent/PT2424546E/pt unknown
- 2010-04-30 US US12/771,289 patent/US8470800B2/en not_active Expired - Fee Related
- 2010-04-30 DK DK10770402.5T patent/DK2424546T3/en active
- 2010-04-30 SI SI201031070T patent/SI2424546T1/sl unknown
- 2010-04-30 JP JP2012508764A patent/JP5778663B2/ja not_active Expired - Fee Related
- 2010-04-30 EA EA201171339A patent/EA024042B1/ru not_active IP Right Cessation
- 2010-04-30 MX MX2011011229A patent/MX2011011229A/es unknown
- 2010-04-30 AU AU2010242943A patent/AU2010242943B2/en not_active Ceased
- 2010-04-30 BR BRPI1009971A patent/BRPI1009971A2/pt not_active IP Right Cessation
- 2010-04-30 KR KR1020117025057A patent/KR101757940B1/ko not_active Expired - Fee Related
- 2010-04-30 SG SG2011078151A patent/SG175346A1/en unknown
- 2010-04-30 CN CN201080018539.XA patent/CN102413832B/zh not_active Expired - Fee Related
- 2010-04-30 EP EP10770402.5A patent/EP2424546B1/en active Active
- 2010-04-30 ES ES10770402.5T patent/ES2554684T3/es active Active
- 2010-04-30 WO PCT/US2010/033112 patent/WO2010127210A1/en not_active Ceased
- 2010-04-30 RS RS20150782A patent/RS54378B1/sr unknown
- 2010-04-30 PL PL10770402T patent/PL2424546T3/pl unknown
- 2010-04-30 CA CA2762064A patent/CA2762064A1/en not_active Abandoned
- 2010-04-30 HU HUE10770402A patent/HUE028068T2/en unknown
-
2011
- 2011-10-27 CL CL2011002675A patent/CL2011002675A1/es unknown
- 2011-11-01 IL IL216081A patent/IL216081A/en not_active IP Right Cessation
-
2013
- 2013-04-03 US US13/855,919 patent/US20130217643A1/en not_active Abandoned
-
2015
- 2015-11-30 SM SM201500295T patent/SMT201500295B/it unknown
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