DK2424546T3 - PROCESS FOR REDUCING intraocular pressure IN PEOPLE - Google Patents
PROCESS FOR REDUCING intraocular pressure IN PEOPLE Download PDFInfo
- Publication number
- DK2424546T3 DK2424546T3 DK10770402.5T DK10770402T DK2424546T3 DK 2424546 T3 DK2424546 T3 DK 2424546T3 DK 10770402 T DK10770402 T DK 10770402T DK 2424546 T3 DK2424546 T3 DK 2424546T3
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- DK
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- Prior art keywords
- compound
- iop
- use according
- glaucoma
- eye
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Classifications
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- A61K31/7042—Compounds having saccharide radicals and heterocyclic rings
- A61K31/7052—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides
- A61K31/706—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom
- A61K31/7064—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom containing condensed or non-condensed pyrimidines
- A61K31/7076—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom containing condensed or non-condensed pyrimidines containing purines, e.g. adenosine, adenylic acid
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
- C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
- C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
- C07H19/16—Purine radicals
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- A—HUMAN NECESSITIES
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
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- A61P27/00—Drugs for disorders of the senses
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- A—HUMAN NECESSITIES
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
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Landscapes
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Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US17465509P | 2009-05-01 | 2009-05-01 | |
| US21999009P | 2009-06-24 | 2009-06-24 | |
| PCT/US2010/033112 WO2010127210A1 (en) | 2009-05-01 | 2010-04-30 | Method of reducing intraocular pressure in humans |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DK2424546T3 true DK2424546T3 (en) | 2015-12-14 |
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Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK10770402.5T DK2424546T3 (en) | 2009-05-01 | 2010-04-30 | PROCESS FOR REDUCING intraocular pressure IN PEOPLE |
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| HR (1) | HRP20151200T1 (enExample) |
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Families Citing this family (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE102008062567A1 (de) | 2008-12-16 | 2010-06-17 | Bayer Schering Pharma Aktiengesellschaft | Dipeptoid-Prodrugs und ihre Verwendung |
| DE102009006602A1 (de) * | 2009-01-29 | 2010-08-05 | Bayer Schering Pharma Aktiengesellschaft | Alkylamino-substituierte Dicyanopyridine und deren Aminosäureester-Prodrugs |
| MX2012004225A (es) * | 2009-10-26 | 2012-06-08 | Inotek Pharmaceuticals Corp | Formulacion oftalmica y metodo de fabricacion de la misma. |
| AU2011203897B2 (en) * | 2010-01-11 | 2016-11-17 | Inotek Pharmaceuticals Corporation | Combination, kit and method of reducing intraocular pressure |
| ME02594B (me) | 2010-03-19 | 2017-06-20 | Inotek Pharmaceuticals Corp | Kombinovane kompozicje adenozinskih a1 agonista i ne-selektivnih beta- adrenergičnih receptor blokera za snižavanje intraokularnog pritiska |
| ES2613254T3 (es) * | 2010-03-19 | 2017-05-23 | Inotek Pharmaceuticals Corporation | Composiciones de combinación de agonistas de adenosina A1 e inhibidores de anhidrasa carbónica para reducir la presión intraocular |
| BR112012023749A2 (pt) | 2010-03-26 | 2016-08-23 | Inotek Pharmaceuticals Corp | método para reduzir a pressão intraocular em humanos utilizando n6-ciclopentiladenosina (cpa), derivados de cpa ou pró-fármacos desses |
| DE102010030688A1 (de) | 2010-06-30 | 2012-01-05 | Bayer Schering Pharma Aktiengesellschaft | Substituierte Dicyanopyridine und ihre Verwendung |
| US20120058983A1 (en) * | 2010-09-02 | 2012-03-08 | Bayer Pharma Aktiengesellschaft | Adenosine A1 agonists for the treatment of glaucoma and ocular hypertension |
| BR112014018413A8 (pt) * | 2012-01-26 | 2017-07-11 | Inotek Pharmaceuticals Corp | Polimorfos anidros de nitrato de metila [(2r,3s,4r,5r)-5-(6-(ciclopentilamino)-9h-purin-9-il)-3,4-diidroxitetraidrofuran-2-il)] e processos de preparação do mesmo |
| EA201591433A1 (ru) | 2013-03-15 | 2015-12-30 | Инотек Фармасьютикалс Корпорейшн | Офтальмологические составы |
| CA2967446A1 (en) * | 2014-12-03 | 2016-06-09 | Inotek Pharmaceuticals Corporation | Methods of preventing, reducing or treating macular degeneration |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103087133B (zh) * | 2004-05-26 | 2016-09-14 | 伊诺泰克制药公司 | 嘌呤衍生物作为腺苷a1受体激动剂及其用法 |
| CN101010085B (zh) | 2004-05-26 | 2012-12-26 | 伊诺泰克制药公司 | 嘌呤衍生物作为腺苷a1受体激动剂及其用法 |
| EP1962597A4 (en) * | 2005-11-30 | 2008-12-17 | Inotek Pharmaceuticals Corp | PURINE DERIVATIVES AND METHOD OF USE |
| MX2012004225A (es) * | 2009-10-26 | 2012-06-08 | Inotek Pharmaceuticals Corp | Formulacion oftalmica y metodo de fabricacion de la misma. |
| AU2011203897B2 (en) * | 2010-01-11 | 2016-11-17 | Inotek Pharmaceuticals Corporation | Combination, kit and method of reducing intraocular pressure |
| ME02594B (me) * | 2010-03-19 | 2017-06-20 | Inotek Pharmaceuticals Corp | Kombinovane kompozicje adenozinskih a1 agonista i ne-selektivnih beta- adrenergičnih receptor blokera za snižavanje intraokularnog pritiska |
| ES2613254T3 (es) * | 2010-03-19 | 2017-05-23 | Inotek Pharmaceuticals Corporation | Composiciones de combinación de agonistas de adenosina A1 e inhibidores de anhidrasa carbónica para reducir la presión intraocular |
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2010
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2013
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