EA014062B1 - Вирусные вакцины, полученные из клеток с низкими уровнями остаточной клеточной днк - Google Patents
Вирусные вакцины, полученные из клеток с низкими уровнями остаточной клеточной днк Download PDFInfo
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- EA014062B1 EA014062B1 EA200801221A EA200801221A EA014062B1 EA 014062 B1 EA014062 B1 EA 014062B1 EA 200801221 A EA200801221 A EA 200801221A EA 200801221 A EA200801221 A EA 200801221A EA 014062 B1 EA014062 B1 EA 014062B1
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Classifications
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- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
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- A61K39/145—Orthomyxoviridae, e.g. influenza virus
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- A61K2039/525—Virus
- A61K2039/5252—Virus inactivated (killed)
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2760/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses negative-sense
- C12N2760/00011—Details
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- C12N2760/16111—Influenzavirus A, i.e. influenza A virus
- C12N2760/16151—Methods of production or purification of viral material
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
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- C12N2760/00011—Details
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Landscapes
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- Peptides Or Proteins (AREA)
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- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
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| AU2007209019B2 (en) | 2006-01-27 | 2012-11-29 | Seqirus UK Limited | Influenza vaccines containing hemagglutinin and matrix proteins |
| CA3016948A1 (en) | 2006-09-11 | 2008-03-20 | Seqirus UK Limited | Making influenza virus vaccines without using eggs |
| PT2185191E (pt) * | 2007-06-27 | 2012-11-27 | Novartis Ag | Vacinas contra a gripe com baixo teor de aditivos |
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| EP3459563B1 (en) | 2008-03-18 | 2025-12-17 | Seqirus UK Limited | Improvements in preparation of influenza virus vaccine antigens |
| JP2012507272A (ja) * | 2008-11-05 | 2012-03-29 | グラクソスミスクライン バイオロジカルズ ソシエテ アノニム | 新規な方法 |
| USH2283H1 (en) | 2009-04-27 | 2013-09-03 | Novartis Ag | Vaccines for protecting against influenza |
| HRP20121048T1 (hr) | 2009-05-21 | 2013-02-28 | Novartis Ag | Reverzna genetika korištenjem ne-endogenih pol i promotora |
| WO2011012999A1 (en) | 2009-07-31 | 2011-02-03 | Novartis Ag | Reverse genetics systems |
| EP2485764A4 (en) | 2009-10-09 | 2014-01-29 | Childrens Medical Center | SELECTIVELY DISCONNECTED FULL CELL VACCINE |
| EA023811B1 (ru) | 2009-10-20 | 2016-07-29 | Новартис Аг | Способ получения вируса с использованием конструкции, кодирующей вирусную рнк |
| WO2011138229A1 (en) | 2010-05-03 | 2011-11-10 | Glaxosmithkline Biologicals S.A. | Novel method |
| JP6072677B2 (ja) | 2010-05-06 | 2017-02-01 | ノバルティス アーゲー | 微生物の不活化のための有機ペルオキシド化合物 |
| EP2571520B1 (en) | 2010-05-21 | 2018-04-04 | Seqirus UK Limited | Influenza virus reassortment method |
| DK2575872T3 (da) | 2010-06-01 | 2020-10-19 | Seqirus Uk Ltd | Koncentrering af influenzavaccineantigener uden frysetørring |
| BR112012030616A2 (pt) | 2010-06-01 | 2017-03-01 | Novartis Ag | concentração de antígenos de vacina com liofilização. |
| US8778653B2 (en) | 2010-08-12 | 2014-07-15 | Yisheng Biopharma Holdings Ltd. | Method for reducing DNA impurities in viral compositions |
| EP2605792B1 (en) | 2010-08-20 | 2014-12-10 | Novartis AG | Soluble needle arrays for delivery of influenza vaccines |
| EP2678452B1 (en) * | 2011-02-25 | 2016-02-24 | Novartis AG | Exogenous internal positive control for virus detection |
| KR102002103B1 (ko) | 2011-11-03 | 2019-07-19 | 센티넥스트 테라퓨틱스 에쓰디엔 비에이취디 | 인간 엔테로바이러스에 대한 백신 |
| GB2495341B (en) | 2011-11-11 | 2013-09-18 | Novartis Ag | Fermentation methods and their products |
| AU2013205478B9 (en) | 2012-03-02 | 2014-11-20 | Seqirus UK Limited | Influenza virus reassortment |
| EP2822585B1 (en) | 2012-03-06 | 2017-05-17 | Janssen Vaccines & Prevention B.V. | Improved vaccination against influenza |
| WO2013182498A1 (en) | 2012-06-04 | 2013-12-12 | Novartis Ag | Improved safety testing |
| EP2925356A2 (en) | 2012-12-03 | 2015-10-07 | Novartis AG | Reassortant influenza a viren |
| AU2014229255B2 (en) | 2013-03-13 | 2018-12-13 | Novartis Ag | Influenza B virus reassortment |
| BR112015028314A2 (pt) | 2013-05-10 | 2017-09-19 | Steinman Lawrence | Prevenção do risco de narcolepsia em vacinas para gripe |
| DE202013005130U1 (de) | 2013-06-05 | 2013-09-10 | Novartis Ag | Influenza Virus Reassortierung |
| DE202013005100U1 (de) | 2013-06-05 | 2013-08-26 | Novartis Ag | Influenza Virus Reassortierung |
| CA2914604A1 (en) | 2013-06-06 | 2014-12-11 | Novartis Ag | Influenza virus reassortment |
| US10080792B2 (en) | 2013-09-23 | 2018-09-25 | Engen Bio, Inc. | Influenza vaccine and therapy |
| CN104436157A (zh) | 2013-09-23 | 2015-03-25 | 恩金生物有限公司 | 流感疫苗和治疗 |
| CN104513317B (zh) * | 2013-09-30 | 2018-12-14 | 普莱柯生物工程股份有限公司 | 一种疫苗组合物及其制备方法和应用 |
| KR20160068972A (ko) * | 2013-11-15 | 2016-06-15 | 노파르티스 아게 | 잔여 세포 배양 불순물의 제거 |
| WO2015179979A1 (en) * | 2014-05-28 | 2015-12-03 | National Health Research Institutes | Viral particles as immunogens against enterovirus infection and production thereof |
| EP3313439A2 (en) | 2015-06-26 | 2018-05-02 | Seqirus UK Limited | Antigenically matched influenza vaccines |
| WO2017005880A1 (en) | 2015-07-07 | 2017-01-12 | Seqirus UK Limited | Influenza potency assays |
| EP3184119A1 (en) * | 2015-12-23 | 2017-06-28 | Themis Bioscience GmbH | Chromatography based purification strategies for measles scaffold based viruses |
| CA3080656A1 (en) | 2017-10-30 | 2019-05-09 | Baxalta GmbH | Environmentally compatible detergents for inactivation of lipid-enveloped viruses |
| CN109652384B (zh) * | 2019-02-21 | 2021-10-26 | 昆明理工大学 | 一种体外培养戊型肝炎病毒的方法 |
| CN114929270A (zh) * | 2019-11-07 | 2022-08-19 | 塞其里斯英国有限公司 | 用于生产具有减小的颗粒大小的病毒疫苗的组合物和方法 |
| AU2020389047A1 (en) | 2019-11-18 | 2022-06-02 | Seqirus Pty Ltd. | Method for producing reassortant influenza viruses |
| KR20230157397A (ko) * | 2021-03-30 | 2023-11-16 | 덴카 주식회사 | 인플루엔자 백신 |
| CN115354071A (zh) * | 2022-08-10 | 2022-11-18 | 上海药明生基医药科技有限公司 | 一种检测重组腺相关病毒宿主细胞dna残留的方法 |
| CN116407624B (zh) * | 2023-04-14 | 2024-04-09 | 吉林省农业科学院(中国农业科技东北创新中心) | 一种鸡传染性支气管炎细菌样颗粒疫苗的制备方法和应用 |
| TW202516000A (zh) * | 2023-07-25 | 2025-04-16 | 日商Ｋｍ生物醫藥股份有限公司 | 利用雞蛋培養法進行的去活化流感疫苗的製備方法 |
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