DK391075A - 7-amino-3-cephem-4-carboxylsyrederivater og deres fremstilling - Google Patents
7-amino-3-cephem-4-carboxylsyrederivater og deres fremstillingInfo
- Publication number
- DK391075A DK391075A DK391075A DK391075A DK391075A DK 391075 A DK391075 A DK 391075A DK 391075 A DK391075 A DK 391075A DK 391075 A DK391075 A DK 391075A DK 391075 A DK391075 A DK 391075A
- Authority
- DK
- Denmark
- Prior art keywords
- cephem
- amino
- preparation
- carboxylic acid
- acid derivatives
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D257/00—Heterocyclic compounds containing rings having four nitrogen atoms as the only ring hetero atoms
- C07D257/02—Heterocyclic compounds containing rings having four nitrogen atoms as the only ring hetero atoms not condensed with other rings
- C07D257/04—Five-membered rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C265/00—Derivatives of isocyanic acid
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
- C07D333/02—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings
- C07D333/04—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom
- C07D333/06—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to the ring carbon atoms
- C07D333/24—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Communicable Diseases (AREA)
- Pharmacology & Pharmacy (AREA)
- Oncology (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Cephalosporin Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (4)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US50299174A | 1974-09-03 | 1974-09-03 | |
US50299174 | 1974-09-03 | ||
US05/590,971 US4297489A (en) | 1974-09-03 | 1975-06-27 | 7-α-Amino-substituted acylamino-3-(1-carboxymethyltetrazol-5-ylthiomethyl)-3-cephem-4-carboxylic acids |
US59097175 | 1975-06-27 |
Publications (3)
Publication Number | Publication Date |
---|---|
DK391075A true DK391075A (da) | 1976-03-04 |
DK145262B DK145262B (da) | 1982-10-18 |
DK145262C DK145262C (da) | 1983-03-14 |
Family
ID=27054342
Family Applications (4)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DK391075A DK145262C (da) | 1974-09-03 | 1975-08-29 | Analogifremgangsmaade til fremstilling af cephalosporansyrederivater og estere og salte deraf |
DK367279A DK147483C (da) | 1974-09-03 | 1979-08-31 | Analogifremgangsmaade til fremstilling af cephalosporansyrederivater eller estere og salte deraf |
DK240582A DK148796C (da) | 1974-09-03 | 1982-05-27 | Cephalosporansyrederivater til anvendelse som mellemprodukter ved fremstilling af andre cephalosporansyrederivater |
DK423383A DK162388C (da) | 1974-09-03 | 1983-09-16 | Thioler til anvendelse som mellemprodukter ved fremstilling af cephalosporansyrederivater |
Family Applications After (3)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DK367279A DK147483C (da) | 1974-09-03 | 1979-08-31 | Analogifremgangsmaade til fremstilling af cephalosporansyrederivater eller estere og salte deraf |
DK240582A DK148796C (da) | 1974-09-03 | 1982-05-27 | Cephalosporansyrederivater til anvendelse som mellemprodukter ved fremstilling af andre cephalosporansyrederivater |
DK423383A DK162388C (da) | 1974-09-03 | 1983-09-16 | Thioler til anvendelse som mellemprodukter ved fremstilling af cephalosporansyrederivater |
Country Status (21)
Country | Link |
---|---|
US (1) | US4297489A (da) |
JP (1) | JPS6150956B2 (da) |
AR (1) | AR222771A1 (da) |
BG (1) | BG27091A3 (da) |
CA (4) | CA1135255A (da) |
CH (1) | CH636882A5 (da) |
DD (2) | DD123471A5 (da) |
DE (2) | DE2538804C2 (da) |
DK (4) | DK145262C (da) |
ES (2) | ES440707A1 (da) |
FI (1) | FI62841C (da) |
FR (1) | FR2283686A1 (da) |
HU (1) | HU169490B (da) |
IE (1) | IE43123B1 (da) |
IL (1) | IL48020A (da) |
LU (1) | LU73306A1 (da) |
NL (1) | NL161758C (da) |
NO (1) | NO152509C (da) |
OA (1) | OA05096A (da) |
SE (3) | SE431548B (da) |
YU (5) | YU213275A (da) |
Families Citing this family (14)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4286089A (en) * | 1974-12-27 | 1981-08-25 | Smithkline Corporation | 7-Acyl-3-(substituted tetrazolyl thiomethyl)cephalosporins |
US4101656A (en) * | 1976-07-12 | 1978-07-18 | Smithkline Corporation | 7β-Acylamino-3-(alkanesulfonamidoalkyl substituted tetrazolylthiomethyl) cephalosporins, antibacterial compositions containing them and methods of treating bacterial infections with them |
US4278670A (en) * | 1976-07-12 | 1981-07-14 | Smithkline Corporation | 7-Alpha-oxyiminoacylcephalosporins |
DE2724092A1 (de) * | 1977-05-27 | 1978-12-07 | Smithkline Corp | Cephalosporine, verfahren zu deren herstellung und diese verbindungen enthaltende arzneimittel |
FR2387235A1 (fr) * | 1978-01-23 | 1978-11-10 | Fujisawa Pharmaceutical Co | Procede de preparation de composes d'acide 3,7-disubstitue-3-cephem-4-carboxylique et nouveaux produits ainsi obtenus, ayant une forte activite antibacterienne |
US4243803A (en) * | 1979-07-05 | 1981-01-06 | Bristol-Myers Company | Production of 7-(2-aminomethylphenylacetamido)-3-(1-carboxymethyltetrazol-5-ylthiomethyl)-3-cephem-4-carboxylic acid |
US4374994A (en) * | 1979-07-05 | 1983-02-22 | Bristol-Myers Company | Process for preparation of 5-mercaptotetrazolyl-1-acetic acid |
EP0029998B1 (en) * | 1979-11-30 | 1985-03-06 | Fujisawa Pharmaceutical Co., Ltd. | Cephem compounds, processes for their preparation and pharmaceutical compositions containing them |
JPS56158791A (en) * | 1980-05-10 | 1981-12-07 | Taisho Pharmaceut Co Ltd | Cephalosporin compound |
GR75083B (da) * | 1980-09-17 | 1984-07-13 | Lilly Co Eli | |
JPS57188594A (en) * | 1981-05-15 | 1982-11-19 | Eisai Co Ltd | Preparation of 7-(2-amino-2-phenylacetamido)cephem derivative |
US4448958A (en) * | 1982-10-20 | 1984-05-15 | Bristol-Myers Company | Purification of ceforanide |
US4749522A (en) * | 1985-10-31 | 1988-06-07 | Angio-Medical Corporation | Supercritical fluid extraction of animal derived materials |
DE3641822A1 (de) * | 1986-12-06 | 1988-06-16 | Goedecke Ag | Verwendung von dihydrophenylaminosaeurederivaten und diese enthaltende arzneimittel zur immunmodulation und cytostase |
Family Cites Families (20)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3819623A (en) * | 1968-04-12 | 1974-06-25 | Fujisawa Pharmaceutical Co | 3,7-disubstituted cephalosporin compounds |
DE1953861C2 (de) * | 1969-10-25 | 1982-12-23 | Fujisawa Pharmaceutical Co., Ltd., Osaka | 7-Tetrazolylacetamido-3-thiomethyl-3-cephem-4- carbonsäuren |
US3814755A (en) * | 1972-08-30 | 1974-06-04 | Bristol Myers Co | 7-(omikron-aminomethylphenylacetamido)-3-(tetrazolo(4,5-b)pyridazin-6-ylthiomethyl)-3-cephem-4-carboxylic acid |
GB1478055A (en) * | 1973-07-27 | 1977-06-29 | Erba Carlo Spa | Cephalosporin compounds |
US4074929A (en) | 1973-08-29 | 1978-02-21 | Amp Incorporated | Cable card edge connector |
NL7414119A (nl) * | 1973-10-31 | 1975-05-02 | Fujisawa Pharmaceutical Co | Werkwijze ter bereiding van 1h-tetrazool-5-thiol- derivaten en 1-gesubstitueerde 1h-tetrazool- -5-thiolen. |
US4205166A (en) * | 1974-02-20 | 1980-05-27 | Fujisawa Pharmaceutical Co., Ltd. | 7-Substituted-3-aminoalkyl-, acylaminoalkyl-, or hydroxyalkyl-substituted heterocyclic thiomethyl-3-cephem-4-carboxylic acid derivatives and preparation thereof |
US4107433A (en) * | 1974-02-21 | 1978-08-15 | Beecham Group Limited | Phthalidyl ester of 3-carbomoyloxy cephalosporin derivatives |
US4068074A (en) * | 1974-04-05 | 1978-01-10 | Yamanouchi Pharmaceutical Co., Ltd. | Cephalosporin derivatives having at the 3-position of the cephem ring a heterocyclic thiomethyl group with a carboxy or sulfo group and at the 7-position of the cephem ring an α-heterocylic acylaminophenyl-acetamide group |
US4160086A (en) * | 1974-04-27 | 1979-07-03 | Beecham Group Limited | 3-Heterocyclicthio-7-α-carboxy 2-aryl acetamido cephalosporanic acid |
JPS612674B2 (da) * | 1974-06-20 | 1986-01-27 | Meiji Seika Co | |
US4172196A (en) * | 1974-09-03 | 1979-10-23 | Bristol-Myers Company | Certain 7-α-substituted-α-hydroxyacetamido-3-(1-carboxymethyltetrazol-5-yl-thiomethyl)-3-cephem-4-carboxylic acids |
US4182863A (en) * | 1974-09-03 | 1980-01-08 | Bristol-Myers Company | 7-Amino-3-(1-carboxymethyltetrazol-5-ylthiomethyl)-3-cephem-4-carboxylic acid |
DK154939C (da) * | 1974-12-19 | 1989-06-12 | Takeda Chemical Industries Ltd | Analogifremgangsmaade til fremstilling af thiazolylacetamido-cephemforbindelser eller farmaceutisk acceptable salte eller estere deraf |
US4286089A (en) * | 1974-12-27 | 1981-08-25 | Smithkline Corporation | 7-Acyl-3-(substituted tetrazolyl thiomethyl)cephalosporins |
US4183925A (en) * | 1975-03-27 | 1980-01-15 | Pfizer Inc. | 7-Aminophenylacetamido-Δ3 -cephem antibacterial agents and method of use |
JPS525787A (en) * | 1975-06-27 | 1977-01-17 | Bristol Myers Co | Antiibacterial agent |
US4013648A (en) * | 1975-07-23 | 1977-03-22 | Bristol-Myers Company | Δ2,3 -0-2-Isocephem-4-carboxylic acid and derivatives as antibacterial agents |
US4220644A (en) * | 1976-05-03 | 1980-09-02 | Smithkline Corporation | 7-Acylamino-3-(substituted tetrazolyl thiomethyl) cephalosporins |
US4118563A (en) * | 1977-11-25 | 1978-10-03 | Bristol-Myers Company | Production of 7-(2-aminomethylphenylacetamido-3-(1-carboxymethyltetrazol-5-ylthiomethyl)-3-cephem-4-carboxylic acid |
-
1975
- 1975-06-27 US US05/590,971 patent/US4297489A/en not_active Expired - Lifetime
- 1975-08-21 YU YU02132/75A patent/YU213275A/xx unknown
- 1975-08-27 CA CA000234276A patent/CA1135255A/en not_active Expired
- 1975-08-29 FI FI752434A patent/FI62841C/fi not_active IP Right Cessation
- 1975-08-29 DK DK391075A patent/DK145262C/da not_active IP Right Cessation
- 1975-09-01 DE DE2538804A patent/DE2538804C2/de not_active Expired
- 1975-09-01 NO NO752983A patent/NO152509C/no unknown
- 1975-09-01 SE SE7509702A patent/SE431548B/xx not_active IP Right Cessation
- 1975-09-01 BG BG030902A patent/BG27091A3/xx unknown
- 1975-09-01 DE DE2560655A patent/DE2560655C2/de not_active Expired
- 1975-09-01 IL IL48020A patent/IL48020A/xx unknown
- 1975-09-02 LU LU73306A patent/LU73306A1/xx unknown
- 1975-09-02 FR FR7526936A patent/FR2283686A1/fr active Granted
- 1975-09-02 OA OA55597A patent/OA05096A/xx unknown
- 1975-09-02 HU HUBI521A patent/HU169490B/hu unknown
- 1975-09-03 AR AR260237A patent/AR222771A1/es active
- 1975-09-03 NL NL7510391.A patent/NL161758C/xx active
- 1975-09-03 JP JP50106106A patent/JPS6150956B2/ja not_active Expired
- 1975-09-03 DD DD188166A patent/DD123471A5/xx unknown
- 1975-09-03 DD DD7500196946A patent/DD130787A5/xx unknown
- 1975-09-03 IE IE1916/75A patent/IE43123B1/en unknown
- 1975-09-03 ES ES440707A patent/ES440707A1/es not_active Expired
-
1977
- 1977-04-20 ES ES457998A patent/ES457998A1/es not_active Expired
-
1979
- 1979-08-31 DK DK367279A patent/DK147483C/da active
- 1979-09-14 SE SE7907672A patent/SE435279B/sv not_active IP Right Cessation
-
1980
- 1980-12-02 CH CH890980A patent/CH636882A5/de not_active IP Right Cessation
-
1981
- 1981-03-12 CA CA372,810A patent/CA1123840A/en not_active Expired
- 1981-03-12 CA CA000372811A patent/CA1135254A/en not_active Expired
- 1981-08-24 CA CA000384513A patent/CA1135256A/en not_active Expired
- 1981-09-16 YU YU2232/81A patent/YU44669B/xx unknown
- 1981-09-16 YU YU02230/81A patent/YU223081A/xx unknown
- 1981-09-16 YU YU2233/81A patent/YU44833B/xx unknown
- 1981-09-16 YU YU2231/81A patent/YU44964B/xx unknown
-
1982
- 1982-05-27 DK DK240582A patent/DK148796C/da not_active IP Right Cessation
-
1983
- 1983-09-16 DK DK423383A patent/DK162388C/da active
- 1983-10-07 SE SE8305539A patent/SE453507B/sv not_active IP Right Cessation
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
PUP | Patent expired |