SE7509702L - Farmaceutiskt verdefulla foreningar och sett att framstella desamma - Google Patents

Farmaceutiskt verdefulla foreningar och sett att framstella desamma

Info

Publication number
SE7509702L
SE7509702L SE7509702A SE7509702A SE7509702L SE 7509702 L SE7509702 L SE 7509702L SE 7509702 A SE7509702 A SE 7509702A SE 7509702 A SE7509702 A SE 7509702A SE 7509702 L SE7509702 L SE 7509702L
Authority
SE
Sweden
Prior art keywords
pharmaceutical
produce
way
same
associations
Prior art date
Application number
SE7509702A
Other languages
English (en)
Other versions
SE431548B (sv
Inventor
W J Gottstein
M A Kaplan
A P Granatek
Original Assignee
Bristol Myers Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bristol Myers Co filed Critical Bristol Myers Co
Publication of SE7509702L publication Critical patent/SE7509702L/sv
Publication of SE431548B publication Critical patent/SE431548B/sv

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D257/00—Heterocyclic compounds containing rings having four nitrogen atoms as the only ring hetero atoms
    • C07D257/02—Heterocyclic compounds containing rings having four nitrogen atoms as the only ring hetero atoms not condensed with other rings
    • C07D257/04—Five-membered rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C265/00—Derivatives of isocyanic acid
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
    • C07D333/02—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings
    • C07D333/04—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom
    • C07D333/06—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to the ring carbon atoms
    • C07D333/24—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Communicable Diseases (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Oncology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Cephalosporin Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
SE7509702A 1974-09-03 1975-09-01 Forfarande for framstellning av nya cefalosporinderivat SE431548B (sv)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US50299174A 1974-09-03 1974-09-03
US05/590,971 US4297489A (en) 1974-09-03 1975-06-27 7-α-Amino-substituted acylamino-3-(1-carboxymethyltetrazol-5-ylthiomethyl)-3-cephem-4-carboxylic acids

Publications (2)

Publication Number Publication Date
SE7509702L true SE7509702L (sv) 1976-03-04
SE431548B SE431548B (sv) 1984-02-13

Family

ID=27054342

Family Applications (3)

Application Number Title Priority Date Filing Date
SE7509702A SE431548B (sv) 1974-09-03 1975-09-01 Forfarande for framstellning av nya cefalosporinderivat
SE7907672A SE435279B (sv) 1974-09-03 1979-09-14 1-karboximetyl (respektive etyl) -5-merkapto-tetrazol till anvendning som mellanprodukt for framstellning av cefalosporinforeningar
SE8305539A SE453507B (sv) 1974-09-03 1983-10-07 7-amino-3-(1-karboxi-(legre alkyl)-tetrazol-5-yltiometyl)-3-cefem-4-karboxylsyror till anvendning som mellanprodukter for framstellning av motsvarande 7-acylamido-cefalosporiner

Family Applications After (2)

Application Number Title Priority Date Filing Date
SE7907672A SE435279B (sv) 1974-09-03 1979-09-14 1-karboximetyl (respektive etyl) -5-merkapto-tetrazol till anvendning som mellanprodukt for framstellning av cefalosporinforeningar
SE8305539A SE453507B (sv) 1974-09-03 1983-10-07 7-amino-3-(1-karboxi-(legre alkyl)-tetrazol-5-yltiometyl)-3-cefem-4-karboxylsyror till anvendning som mellanprodukter for framstellning av motsvarande 7-acylamido-cefalosporiner

Country Status (21)

Country Link
US (1) US4297489A (sv)
JP (1) JPS6150956B2 (sv)
AR (1) AR222771A1 (sv)
BG (1) BG27091A3 (sv)
CA (4) CA1135255A (sv)
CH (1) CH636882A5 (sv)
DD (2) DD123471A5 (sv)
DE (2) DE2538804C2 (sv)
DK (4) DK145262C (sv)
ES (2) ES440707A1 (sv)
FI (1) FI62841C (sv)
FR (1) FR2283686A1 (sv)
HU (1) HU169490B (sv)
IE (1) IE43123B1 (sv)
IL (1) IL48020A (sv)
LU (1) LU73306A1 (sv)
NL (1) NL161758C (sv)
NO (1) NO152509C (sv)
OA (1) OA05096A (sv)
SE (3) SE431548B (sv)
YU (5) YU213275A (sv)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4286089A (en) * 1974-12-27 1981-08-25 Smithkline Corporation 7-Acyl-3-(substituted tetrazolyl thiomethyl)cephalosporins
US4101656A (en) * 1976-07-12 1978-07-18 Smithkline Corporation 7β-Acylamino-3-(alkanesulfonamidoalkyl substituted tetrazolylthiomethyl) cephalosporins, antibacterial compositions containing them and methods of treating bacterial infections with them
US4278670A (en) * 1976-07-12 1981-07-14 Smithkline Corporation 7-Alpha-oxyiminoacylcephalosporins
DE2724092A1 (de) * 1977-05-27 1978-12-07 Smithkline Corp Cephalosporine, verfahren zu deren herstellung und diese verbindungen enthaltende arzneimittel
FR2387235A1 (fr) * 1978-01-23 1978-11-10 Fujisawa Pharmaceutical Co Procede de preparation de composes d'acide 3,7-disubstitue-3-cephem-4-carboxylique et nouveaux produits ainsi obtenus, ayant une forte activite antibacterienne
US4374994A (en) * 1979-07-05 1983-02-22 Bristol-Myers Company Process for preparation of 5-mercaptotetrazolyl-1-acetic acid
US4243803A (en) * 1979-07-05 1981-01-06 Bristol-Myers Company Production of 7-(2-aminomethylphenylacetamido)-3-(1-carboxymethyltetrazol-5-ylthiomethyl)-3-cephem-4-carboxylic acid
DE3070258D1 (en) * 1979-11-30 1985-04-11 Fujisawa Pharmaceutical Co Cephem compounds, processes for their preparation and pharmaceutical compositions containing them
JPS56158791A (en) * 1980-05-10 1981-12-07 Taisho Pharmaceut Co Ltd Cephalosporin compound
IL63767A0 (en) * 1980-09-17 1981-12-31 Lilly Co Eli Cephalosporin compounds
JPS57188594A (en) * 1981-05-15 1982-11-19 Eisai Co Ltd Preparation of 7-(2-amino-2-phenylacetamido)cephem derivative
US4448958A (en) * 1982-10-20 1984-05-15 Bristol-Myers Company Purification of ceforanide
US4749522A (en) * 1985-10-31 1988-06-07 Angio-Medical Corporation Supercritical fluid extraction of animal derived materials
DE3641822A1 (de) * 1986-12-06 1988-06-16 Goedecke Ag Verwendung von dihydrophenylaminosaeurederivaten und diese enthaltende arzneimittel zur immunmodulation und cytostase

Family Cites Families (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3819623A (en) * 1968-04-12 1974-06-25 Fujisawa Pharmaceutical Co 3,7-disubstituted cephalosporin compounds
DE1953861C2 (de) * 1969-10-25 1982-12-23 Fujisawa Pharmaceutical Co., Ltd., Osaka 7-Tetrazolylacetamido-3-thiomethyl-3-cephem-4- carbonsäuren
US3814755A (en) * 1972-08-30 1974-06-04 Bristol Myers Co 7-(omikron-aminomethylphenylacetamido)-3-(tetrazolo(4,5-b)pyridazin-6-ylthiomethyl)-3-cephem-4-carboxylic acid
GB1478055A (en) 1973-07-27 1977-06-29 Erba Carlo Spa Cephalosporin compounds
US4074929A (en) 1973-08-29 1978-02-21 Amp Incorporated Cable card edge connector
US4110338A (en) * 1973-10-31 1978-08-29 Fujisawa Pharmaceutical Co., Ltd. Product and preparation of 1H-tetrazole-5-thiol derivatives
US4205166A (en) * 1974-02-20 1980-05-27 Fujisawa Pharmaceutical Co., Ltd. 7-Substituted-3-aminoalkyl-, acylaminoalkyl-, or hydroxyalkyl-substituted heterocyclic thiomethyl-3-cephem-4-carboxylic acid derivatives and preparation thereof
US4092476A (en) * 1974-02-21 1978-05-30 Beecham Group Limited Phthalidyl esters of 7-[(α amino, 2 substituted acetamido)-3-(heterocyclic-thio methyl)]cephalosporins
US4068074A (en) * 1974-04-05 1978-01-10 Yamanouchi Pharmaceutical Co., Ltd. Cephalosporin derivatives having at the 3-position of the cephem ring a heterocyclic thiomethyl group with a carboxy or sulfo group and at the 7-position of the cephem ring an α-heterocylic acylaminophenyl-acetamide group
US4160086A (en) * 1974-04-27 1979-07-03 Beecham Group Limited 3-Heterocyclicthio-7-α-carboxy 2-aryl acetamido cephalosporanic acid
JPS612674B2 (sv) * 1974-06-20 1986-01-27 Meiji Seika Co
US4172196A (en) * 1974-09-03 1979-10-23 Bristol-Myers Company Certain 7-α-substituted-α-hydroxyacetamido-3-(1-carboxymethyltetrazol-5-yl-thiomethyl)-3-cephem-4-carboxylic acids
US4182863A (en) * 1974-09-03 1980-01-08 Bristol-Myers Company 7-Amino-3-(1-carboxymethyltetrazol-5-ylthiomethyl)-3-cephem-4-carboxylic acid
DK154939C (da) * 1974-12-19 1989-06-12 Takeda Chemical Industries Ltd Analogifremgangsmaade til fremstilling af thiazolylacetamido-cephemforbindelser eller farmaceutisk acceptable salte eller estere deraf
US4286089A (en) * 1974-12-27 1981-08-25 Smithkline Corporation 7-Acyl-3-(substituted tetrazolyl thiomethyl)cephalosporins
US4183925A (en) * 1975-03-27 1980-01-15 Pfizer Inc. 7-Aminophenylacetamido-Δ3 -cephem antibacterial agents and method of use
JPS525787A (en) * 1975-06-27 1977-01-17 Bristol Myers Co Antiibacterial agent
US4013648A (en) * 1975-07-23 1977-03-22 Bristol-Myers Company Δ2,3 -0-2-Isocephem-4-carboxylic acid and derivatives as antibacterial agents
US4220644A (en) * 1976-05-03 1980-09-02 Smithkline Corporation 7-Acylamino-3-(substituted tetrazolyl thiomethyl) cephalosporins
US4118563A (en) * 1977-11-25 1978-10-03 Bristol-Myers Company Production of 7-(2-aminomethylphenylacetamido-3-(1-carboxymethyltetrazol-5-ylthiomethyl)-3-cephem-4-carboxylic acid

Also Published As

Publication number Publication date
DK423383D0 (da) 1983-09-16
DK162388C (da) 1992-03-16
DK423383A (da) 1983-09-16
ES457998A1 (es) 1978-03-01
NO152509B (no) 1985-07-01
FI752434A (sv) 1976-03-04
SE431548B (sv) 1984-02-13
FR2283686B1 (sv) 1983-07-08
YU223181A (en) 1983-12-31
OA05096A (fr) 1981-01-31
SE7907672L (sv) 1979-09-14
NL161758C (nl) 1980-03-17
YU223281A (en) 1983-12-31
YU223081A (en) 1983-12-31
DK391075A (da) 1976-03-04
CA1135255A (en) 1982-11-09
FR2283686A1 (fr) 1976-04-02
CH636882A5 (de) 1983-06-30
DD123471A5 (sv) 1976-12-20
IL48020A (en) 1982-02-28
DK148796B (da) 1985-09-30
FI62841B (fi) 1982-11-30
BG27091A3 (sv) 1979-08-15
DK145262B (da) 1982-10-18
YU44669B (en) 1990-12-31
HU169490B (sv) 1976-12-28
CA1123840A (en) 1982-05-18
DE2538804C2 (de) 1986-10-16
DE2538804A1 (de) 1976-07-15
IE43123L (en) 1976-03-03
YU44833B (en) 1991-04-30
SE8305539D0 (sv) 1983-10-07
NO752983L (sv) 1976-03-04
DD130787A5 (de) 1978-05-03
LU73306A1 (sv) 1976-08-13
DK145262C (da) 1983-03-14
DK240582A (da) 1982-05-27
DK147483B (da) 1984-08-27
YU213275A (en) 1982-02-28
DK162388B (da) 1991-10-21
NL7510391A (nl) 1976-03-05
JPS6150956B2 (sv) 1986-11-06
DK147483C (da) 1985-03-25
CA1135254A (en) 1982-11-09
DE2560655C2 (sv) 1988-07-14
NO152509C (no) 1985-10-09
US4297489A (en) 1981-10-27
DK367279A (da) 1979-08-31
FI62841C (fi) 1983-03-10
ES440707A1 (es) 1977-07-01
JPS5154580A (sv) 1976-05-13
AR222771A1 (es) 1981-06-30
IE43123B1 (en) 1980-12-31
DK148796C (da) 1986-03-17
SE8305539L (sv) 1983-10-07
YU223381A (en) 1983-06-30
YU44964B (en) 1991-06-30
CA1135256A (en) 1982-11-09
SE453507B (sv) 1988-02-08
IL48020A0 (en) 1975-11-25
SE435279B (sv) 1984-09-17

Similar Documents

Publication Publication Date Title
SE7509702L (sv) Farmaceutiskt verdefulla foreningar och sett att framstella desamma
BE801090A (fr) Recuperation d'acides de solutions aqueuses
FR2437406A1 (fr) Derives d'acide quinoleinecarboxylique substitue et leur utilisation comme agents antibacteriens
FR2336126A1 (fr) Derives d'esters d'acide phenylacetique
AR205196A1 (es) Procedimiento de preparacion de derivados de acidos n n'-bis(triiodocarbamoil - amino - benzoil)-diamino-alcanoicos
BE812772A (fr) Derives de l'acide 2-anilino-nicotinique
BE835268A (fr) Derives de l'acide furannehydroxyamique
BE792179A (fr) Derives de l'acide citrique
ES411112A1 (es) Procedimiento de preparacion de nuevos derivados del 1'1- difenil-etileno.
BE802356A (fr) Derives de l'acide succinique
ES415633A2 (es) Procedimiento de preparacion de nuevos esteres aminoalcohi-lados de acidos anilino-2 nicotinicos.
BE792181A (fr) Derives de l'acide citrique
BE808591A (fr) Derives d'acide amidomethane-phosphonique
BE802719A (fr) Derives de l'acide 9-hydroxy-13-trans-prostenoique
FR2279754A1 (fr) Procede de preparation de derives de l'acide 7-aminocephalosporanique
BE827415A (fr) Derives de l'acide salicylique
BE828186A (fr) Derives de l'acide prostanoique
RO71431A (ro) Procedeu de preparare a derivatilor acidului pregnanic
NZ181804A (en) 7 -(d-2-amino-2-(alkyl sulphonylamino-phenyl)-acetamido)-3-cephem-4-carboxylic acids their salts and pharmaceutical compositions
BE812250A (fr) Procedes de preparation de derives d'acide alkyl inferieur-2 ou3-cephem-4-carboxylique
FR2287230A1 (fr) Derives de l'acide cephalosporanique
BE832098A (fr) Derives de l'acide prostanoique
BE788850A (fr) Derives d'acide benzoique
BE837766A (fr) Preparation de derives de l'acide 7-aminocephalosporanique
BE787457A (fr) Derives de l'acide chloro-2-ethanephosphonique

Legal Events

Date Code Title Description
NAL Patent in force

Ref document number: 7509702-2

Format of ref document f/p: F

NUG Patent has lapsed

Ref document number: 7509702-2

Format of ref document f/p: F