DK373487D0 - N-fosfonylmetoxyalkylpyrimidiner og -puriner samt farmaceutisk praeparat indeholdende saadanne forbindelser - Google Patents

N-fosfonylmetoxyalkylpyrimidiner og -puriner samt farmaceutisk praeparat indeholdende saadanne forbindelser

Info

Publication number
DK373487D0
DK373487D0 DK373487A DK373487A DK373487D0 DK 373487 D0 DK373487 D0 DK 373487D0 DK 373487 A DK373487 A DK 373487A DK 373487 A DK373487 A DK 373487A DK 373487 D0 DK373487 D0 DK 373487D0
Authority
DK
Denmark
Prior art keywords
compounds
phosphonylmetoxyalkyl
purines
pyrimidines
pharmaceutical preparation
Prior art date
Application number
DK373487A
Other languages
English (en)
Other versions
DK170646B1 (da
DK373487A (da
Inventor
Erik Declercq
Antonin Holy
Ivan Rosenberg
Original Assignee
Stichting Rega V Z W
Ceskoslovenska Akademie Ved
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Stichting Rega V Z W, Ceskoslovenska Akademie Ved filed Critical Stichting Rega V Z W
Publication of DK373487D0 publication Critical patent/DK373487D0/da
Publication of DK373487A publication Critical patent/DK373487A/da
Application granted granted Critical
Publication of DK170646B1 publication Critical patent/DK170646B1/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02—Phosphorus compounds
    • C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02—Phosphorus compounds
    • C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
    • C07F9/6561—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom containing systems of two or more relevant hetero rings condensed among themselves or condensed with a common carbocyclic ring or ring system, with or without other non-condensed hetero rings
    • C07F9/65616—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom containing systems of two or more relevant hetero rings condensed among themselves or condensed with a common carbocyclic ring or ring system, with or without other non-condensed hetero rings containing the ring system having three or more than three double bonds between ring members or between ring members and non-ring members, e.g. purine or analogs
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02—Phosphorus compounds
    • C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
    • C07F9/645—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having two nitrogen atoms as the only ring hetero atoms
    • C07F9/6509—Six-membered rings
    • C07F9/6512—Six-membered rings having the nitrogen atoms in positions 1 and 3

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Virology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Communicable Diseases (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Oncology (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Transition And Organic Metals Composition Catalysts For Addition Polymerization (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
DK373487A 1986-07-18 1987-07-17 N-fosfonylmetoxyalkylderivater af pyrimidinbaser og purinbaser, fremgangsmåder til fremstilling heraf, samt lægemiddelpræparat med antiviral virkning indeholdende et sådant derivat DK170646B1 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
CS865469A CS264222B1 (en) 1986-07-18 1986-07-18 N-phosphonylmethoxyalkylderivatives of bases of pytimidine and purine and method of use them
CS546986 1986-07-18

Publications (3)

Publication Number Publication Date
DK373487D0 true DK373487D0 (da) 1987-07-17
DK373487A DK373487A (da) 1988-01-19
DK170646B1 DK170646B1 (da) 1995-11-20

Family

ID=5399635

Family Applications (1)

Application Number Title Priority Date Filing Date
DK373487A DK170646B1 (da) 1986-07-18 1987-07-17 N-fosfonylmetoxyalkylderivater af pyrimidinbaser og purinbaser, fremgangsmåder til fremstilling heraf, samt lægemiddelpræparat med antiviral virkning indeholdende et sådant derivat

Country Status (21)

Country Link
US (3) US5142051A (da)
EP (1) EP0253412B1 (da)
JP (1) JPH0822866B2 (da)
KR (1) KR950004179B1 (da)
AT (1) ATE57932T1 (da)
AU (1) AU600002B2 (da)
CA (1) CA1340856C (da)
CS (1) CS264222B1 (da)
DE (2) DE19775085I2 (da)
DK (1) DK170646B1 (da)
EG (1) EG18273A (da)
ES (1) ES2036194T3 (da)
FI (1) FI86856C (da)
GR (1) GR3002534T3 (da)
IE (1) IE60117B1 (da)
IL (1) IL83235A (da)
LU (1) LU90155I2 (da)
NL (1) NL970036I2 (da)
NZ (1) NZ221100A (da)
PT (1) PT85354B (da)
ZA (1) ZA875283B (da)

Families Citing this family (83)

* Cited by examiner, † Cited by third party
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CS264222B1 (en) * 1986-07-18 1989-06-13 Holy Antonin N-phosphonylmethoxyalkylderivatives of bases of pytimidine and purine and method of use them
US5650510A (en) * 1986-11-18 1997-07-22 Institute Of Organic Chemistry And Biochemistry Of The Academy Of Sciences Of The Czech Republic Antiviral phosphonomethoxyalkylene purine and pyrimidine derivatives
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JPH0217199A (ja) * 1988-07-05 1990-01-22 Japan Tobacco Inc ２’−デオキシ−β−アデノシンの製造方法
US5688778A (en) * 1989-05-15 1997-11-18 Institute Of Organic Chemistry And Biochemistry Of The Academy Of Sciences Of The Czech Republic Nucleoside analogs
US5302585A (en) * 1990-04-20 1994-04-12 Institute Of Organic Chemistry And Biochemistry Of The Academy Of Sciences Of The Czech Republic Use of chiral 2-(phosphonomethoxy)propyl guanines as antiviral agents
ATE124050T1 (de) * 1990-04-20 1995-07-15 Acad Of Science Czech Republic Chirale 2-(phosphonomethoxy)propyl-guanine als antivirale agentien.
SK280313B6 (sk) * 1990-04-24 1999-11-08 �Stav Organick� Chemie A Biochemie Av �R N-(3-fluór-2-fosfonylmetoxypropyl)deriváty purínov
CS276072B6 (en) * 1990-08-06 1992-03-18 Ustav Organicke Chemie A Bioch (2R)-2-/DI(2-PROPYL)PHOSPHONYLMETHOXY/-3-p-TOLUENESULFONYLOXY -1- TRIMETHYLACETOXYPROPANE AND PROCESS FOR PREPARING THEREOF
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Also Published As

Publication number Publication date
NL970036I1 (nl) 1997-12-01
ZA875283B (en) 1988-03-30
CS264222B1 (en) 1989-06-13
DK170646B1 (da) 1995-11-20
FI873165A0 (fi) 1987-07-17
CS546986A1 (en) 1988-08-16
KR880001688A (ko) 1988-04-26
DE19775085I2 (de) 2004-01-15
US5641763A (en) 1997-06-24
FI86856B (fi) 1992-07-15
IE871944L (en) 1988-01-18
NZ221100A (en) 1991-09-25
IL83235A0 (en) 1987-12-31
US5142051A (en) 1992-08-25
PT85354A (en) 1987-08-01
US5869467A (en) 1999-02-09
EG18273A (en) 1992-12-30
DK373487A (da) 1988-01-19
ES2036194T3 (es) 1993-05-16
FI873165A (fi) 1988-01-19
AU7575987A (en) 1988-01-21
EP0253412A3 (en) 1989-04-26
IE60117B1 (en) 1994-06-01
CA1340856C (en) 1999-12-21
AU600002B2 (en) 1990-08-02
GR3002534T3 (en) 1993-01-25
EP0253412A2 (en) 1988-01-20
JPS6345289A (ja) 1988-02-26
JPH0822866B2 (ja) 1996-03-06
IL83235A (en) 1992-11-15
DE3765864D1 (de) 1990-12-06
ATE57932T1 (de) 1990-11-15
NL970036I2 (nl) 1998-03-02
PT85354B (pt) 1990-04-30
EP0253412B1 (en) 1990-10-31
FI86856C (fi) 1992-10-26
KR950004179B1 (en) 1995-04-27
LU90155I2 (fr) 1997-12-22

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