ATE60604T1 - 1h-indol-3-yl enthaltende 1,3-dimethyl-1-h-purine-2,6-dione. - Google Patents
1h-indol-3-yl enthaltende 1,3-dimethyl-1-h-purine-2,6-dione.Info
- Publication number
- ATE60604T1 ATE60604T1 AT85201484T AT85201484T ATE60604T1 AT E60604 T1 ATE60604 T1 AT E60604T1 AT 85201484 T AT85201484 T AT 85201484T AT 85201484 T AT85201484 T AT 85201484T AT E60604 T1 ATE60604 T1 AT E60604T1
- Authority
- AT
- Austria
- Prior art keywords
- indol
- purine
- dimethyl
- compounds
- dione
- Prior art date
Links
- -1 1H-INDOL-3-YL Chemical class 0.000 title 1
- 150000001875 compounds Chemical class 0.000 abstract 3
- 239000008194 pharmaceutical composition Substances 0.000 abstract 2
- 239000002253 acid Substances 0.000 abstract 1
- 239000004480 active ingredient Substances 0.000 abstract 1
- 230000002539 anti-aggressive effect Effects 0.000 abstract 1
- 230000002180 anti-stress Effects 0.000 abstract 1
- 239000002249 anxiolytic agent Substances 0.000 abstract 1
- 230000000949 anxiolytic effect Effects 0.000 abstract 1
- 230000000694 effects Effects 0.000 abstract 1
- 125000000814 indol-3-yl group Chemical group [H]C1=C([H])C([H])=C2N([H])C([H])=C([*])C2=C1[H] 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
- 230000001624 sedative effect Effects 0.000 abstract 1
- ZFXYFBGIUFBOJW-UHFFFAOYSA-N theophylline Chemical class O=C1N(C)C(=O)N(C)C2=C1NC=N2 ZFXYFBGIUFBOJW-UHFFFAOYSA-N 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D473/00—Heterocyclic compounds containing purine ring systems
- C07D473/02—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6
- C07D473/04—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6 two oxygen atoms
- C07D473/06—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6 two oxygen atoms with radicals containing only hydrogen and carbon atoms, attached in position 1 or 3
- C07D473/08—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6 two oxygen atoms with radicals containing only hydrogen and carbon atoms, attached in position 1 or 3 with methyl radicals in positions 1 and 3, e.g. theophylline
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/08—Drugs for disorders of the alimentary tract or the digestive system for nausea, cinetosis or vertigo; Antiemetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/20—Hypnotics; Sedatives
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Veterinary Medicine (AREA)
- Life Sciences & Earth Sciences (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Engineering & Computer Science (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Biomedical Technology (AREA)
- Neurosurgery (AREA)
- Neurology (AREA)
- Pain & Pain Management (AREA)
- Anesthesiology (AREA)
- Hospice & Palliative Care (AREA)
- Otolaryngology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Indole Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US06/656,561 US4548939A (en) | 1984-10-01 | 1984-10-01 | 1H-Indol-3-yl containing 1,3-dimethyl-1H-purine-2,6-diones |
| EP85201484A EP0177087B1 (de) | 1984-10-01 | 1985-09-18 | 1H-Indol-3-yl enthaltende 1,3-Dimethyl-1-H-purine-2,6-dione |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE60604T1 true ATE60604T1 (de) | 1991-02-15 |
Family
ID=24633577
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT85201484T ATE60604T1 (de) | 1984-10-01 | 1985-09-18 | 1h-indol-3-yl enthaltende 1,3-dimethyl-1-h-purine-2,6-dione. |
Country Status (17)
| Country | Link |
|---|---|
| US (1) | US4548939A (de) |
| EP (1) | EP0177087B1 (de) |
| JP (1) | JPH0653742B2 (de) |
| CN (1) | CN1011311B (de) |
| AT (1) | ATE60604T1 (de) |
| AU (1) | AU576386B2 (de) |
| CA (1) | CA1262348A (de) |
| DE (1) | DE3581577D1 (de) |
| DK (1) | DK163996C (de) |
| ES (1) | ES8609324A1 (de) |
| FI (1) | FI83220C (de) |
| GR (1) | GR852375B (de) |
| IE (1) | IE58747B1 (de) |
| NO (1) | NO162069C (de) |
| NZ (1) | NZ213498A (de) |
| PT (1) | PT81229B (de) |
| ZA (1) | ZA857553B (de) |
Families Citing this family (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CH648559A5 (de) * | 1981-07-20 | 1985-03-29 | Siegfried Ag | Theophyllinderivate und verfahren zu deren herstellung. |
| US4742057A (en) * | 1985-12-05 | 1988-05-03 | Fujisawa Pharmaceutical Co., Ltd. | Antiallergic thiazole compounds |
| AU611469B2 (en) * | 1987-08-13 | 1991-06-13 | Glaxo Group Limited | Indole derivatives |
| GB8719167D0 (en) * | 1987-08-13 | 1987-09-23 | Glaxo Group Ltd | Chemical compounds |
| DK733788A (da) * | 1988-01-14 | 1989-07-15 | Fujisawa Pharmaceutical Co | Indolylpiperidinderivater og fremgangsmaade til fremstilling deraf |
| GB8819024D0 (en) * | 1988-08-10 | 1988-09-14 | Glaxo Group Ltd | Chemical compounds |
| DE8817122U1 (de) * | 1988-12-22 | 1993-02-04 | Boehringer Ingelheim Kg, 55218 Ingelheim | Neue Xanthinderivate mit Adenosinantogenistischer Wirkung |
| DK292A (da) * | 1991-11-29 | 1992-01-02 | Tanisake Kk | Middel |
| DE4414113A1 (de) * | 1994-04-22 | 1995-10-26 | Merck Patent Gmbh | 3-Indolylpiperidine |
| WO2009002933A1 (en) * | 2007-06-22 | 2008-12-31 | Hydra Biosciences, Inc. | Methods and compositions for treating disorders |
| WO2010039289A2 (en) | 2008-05-14 | 2010-04-08 | Hydra Biosciences, Inc. | Compounds and compositions for treating chemical warfare agent-induced injuries |
| WO2009140517A1 (en) | 2008-05-14 | 2009-11-19 | Hydra Biosciences, Inc. | Compounds and compositions for treating chemical warfare agent-induced injuries |
Family Cites Families (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE2322470A1 (de) * | 1973-05-04 | 1974-11-21 | Boehringer Sohn Ingelheim | Neue indolyl-piperidino-(bzw. 1,2,5,6tetrahydro-pyridyl-)butyrophenone und verfahren zu ihrer herstellung |
| FR2334358A1 (fr) * | 1975-12-12 | 1977-07-08 | Sogeras | Nouveaux medicaments derives de l'indole |
| FR2362628A1 (fr) * | 1976-08-26 | 1978-03-24 | Roussel Uclaf | Nouveaux derives du piperidyl-indole et leurs sels, procede de preparation et application a titre de medicaments |
| EP0011399A1 (de) * | 1978-11-11 | 1980-05-28 | FISONS plc | N-Substituierte Theophylline, Verfahren zu ihrer Herstellung und diese enthaltende pharmazeutische Präparate |
| DE2922159A1 (de) * | 1979-05-31 | 1980-12-04 | Boehringer Mannheim Gmbh | Neue xanthin-derivate, verfahren zu ihrer herstellung und diese verbindungen enthaltende arzneimittel |
| US4342870A (en) * | 1980-03-28 | 1982-08-03 | Janssen Pharmaceutica N.V. | Novel 3-(1-piperidinylalkyl)-4H-pyrido[1,2-a]pyrimidin-4-one derivatives |
| US4426383A (en) * | 1980-09-04 | 1984-01-17 | Eisai Co., Ltd. | Theophylline and theobromine derivatives |
| US4359468A (en) * | 1981-02-25 | 1982-11-16 | Boehringer Ingelheim Ltd. | Antiallergic N-[4-(indolyl)-piperidino-alkyl]-benzimidazolones |
| US4443451A (en) * | 1981-07-15 | 1984-04-17 | Janssen Pharmaceutica N.V. | Bicyclic pyrimidin-5-one derivatives |
| CH648559A5 (de) * | 1981-07-20 | 1985-03-29 | Siegfried Ag | Theophyllinderivate und verfahren zu deren herstellung. |
-
1984
- 1984-10-01 US US06/656,561 patent/US4548939A/en not_active Expired - Fee Related
-
1985
- 1985-07-30 CN CN85105804A patent/CN1011311B/zh not_active Expired
- 1985-09-10 CA CA000490317A patent/CA1262348A/en not_active Expired
- 1985-09-16 NZ NZ213498A patent/NZ213498A/en unknown
- 1985-09-18 EP EP85201484A patent/EP0177087B1/de not_active Expired - Lifetime
- 1985-09-18 AT AT85201484T patent/ATE60604T1/de not_active IP Right Cessation
- 1985-09-18 DE DE8585201484T patent/DE3581577D1/de not_active Expired - Fee Related
- 1985-09-27 JP JP60212731A patent/JPH0653742B2/ja not_active Expired - Lifetime
- 1985-09-30 ES ES547447A patent/ES8609324A1/es not_active Expired
- 1985-09-30 DK DK444085A patent/DK163996C/da not_active IP Right Cessation
- 1985-09-30 GR GR852375A patent/GR852375B/el unknown
- 1985-09-30 FI FI853763A patent/FI83220C/fi not_active IP Right Cessation
- 1985-09-30 NO NO853856A patent/NO162069C/no unknown
- 1985-09-30 ZA ZA857553A patent/ZA857553B/xx unknown
- 1985-09-30 IE IE240385A patent/IE58747B1/en not_active IP Right Cessation
- 1985-09-30 AU AU48124/85A patent/AU576386B2/en not_active Ceased
- 1985-10-01 PT PT81229A patent/PT81229B/pt not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| FI853763A0 (fi) | 1985-09-30 |
| ES8609324A1 (es) | 1986-07-16 |
| US4548939A (en) | 1985-10-22 |
| AU576386B2 (en) | 1988-08-25 |
| FI83220B (fi) | 1991-02-28 |
| AU4812485A (en) | 1986-04-10 |
| DK163996B (da) | 1992-04-27 |
| NO853856L (no) | 1986-04-02 |
| GR852375B (de) | 1986-01-31 |
| CN85105804A (zh) | 1986-10-22 |
| NO162069C (no) | 1989-11-01 |
| EP0177087A3 (en) | 1986-06-11 |
| DE3581577D1 (de) | 1991-03-07 |
| NZ213498A (en) | 1988-04-29 |
| ES547447A0 (es) | 1986-07-16 |
| ZA857553B (en) | 1987-05-27 |
| JPH0653742B2 (ja) | 1994-07-20 |
| DK444085A (da) | 1986-04-02 |
| EP0177087B1 (de) | 1991-01-30 |
| CA1262348A (en) | 1989-10-17 |
| CN1011311B (zh) | 1991-01-23 |
| IE58747B1 (en) | 1993-11-03 |
| DK163996C (da) | 1992-09-21 |
| IE852403L (en) | 1986-04-01 |
| PT81229B (pt) | 1987-11-30 |
| DK444085D0 (da) | 1985-09-30 |
| NO162069B (no) | 1989-07-24 |
| FI853763L (fi) | 1986-04-02 |
| EP0177087A2 (de) | 1986-04-09 |
| FI83220C (fi) | 1991-06-10 |
| PT81229A (en) | 1985-11-01 |
| JPS6187681A (ja) | 1986-05-06 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| ES8603870A1 (es) | Un procedimiento para la preparacion de derivados de 2,2'-iminobisetanol. | |
| ES8602763A1 (es) | Un procedimiento para la preparacion de n-(heterociclilbiciclo)-4-piperidinaminas. | |
| ES8706668A1 (es) | Un procedimiento para la preparacion de derivados de piperidina. | |
| ES8601965A1 (es) | Un procedimiento para la preparacion de una nueva serie de derivados de (1-piperidinilalquil)pirimidinona | |
| PH25504A (en) | Novel substituted n-(1-alkyl-3-hydroxy-4-piperidinyl)benzamides pharmaceutical composition containing said compound, method of use thereof | |
| ATE60604T1 (de) | 1h-indol-3-yl enthaltende 1,3-dimethyl-1-h-purine-2,6-dione. | |
| EP0184258A3 (en) | Novel derivatives of hydroxy- or amino-substituted (piperidinylalkyl)quinazolines | |
| ATE48001T1 (de) | Cephemverbindungen, verfahren zu ihrer herstellung und ihre pharmazeutischen praeparate. | |
| HUT53664A (en) | Process for producing enzyme inhibiting amino acid derivatives and pharmaceutical compositions comprising such compounds as active ingredient | |
| GR852395B (de) | ||
| HK47592A (en) | Piperazine derivatives | |
| EP0321967A3 (en) | Compounds active on the cardiovascular system |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| UEP | Publication of translation of european patent specification | ||
| REN | Ceased due to non-payment of the annual fee |