NO853856L - Fremgangsm¨te for fremstilling av 1h-indol-3-yl-inneholden de 1,3-dimetyl-1h-purin-2,6-dioner. - Google Patents

Fremgangsm¨te for fremstilling av 1h-indol-3-yl-inneholden de 1,3-dimetyl-1h-purin-2,6-dioner.

Info

Publication number
NO853856L
NO853856L NO853856A NO853856A NO853856L NO 853856 L NO853856 L NO 853856L NO 853856 A NO853856 A NO 853856A NO 853856 A NO853856 A NO 853856A NO 853856 L NO853856 L NO 853856L
Authority
NO
Norway
Prior art keywords
indol
dimethyl
purin
dione
procedure
Prior art date
Application number
NO853856A
Other languages
English (en)
Other versions
NO162069C (no
NO162069B (no
Inventor
Ludo Edmond Josephine Kennis
Jan Vandenberk
Jozef Martin Boey
Original Assignee
Janssen Pharmaceutica Nv
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Janssen Pharmaceutica Nv filed Critical Janssen Pharmaceutica Nv
Publication of NO853856L publication Critical patent/NO853856L/no
Publication of NO162069B publication Critical patent/NO162069B/no
Publication of NO162069C publication Critical patent/NO162069C/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D473/00—Heterocyclic compounds containing purine ring systems
    • C07D473/02—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6
    • C07D473/04—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6 two oxygen atoms
    • C07D473/06—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6 two oxygen atoms with radicals containing only hydrogen and carbon atoms, attached in position 1 or 3
    • C07D473/08—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6 two oxygen atoms with radicals containing only hydrogen and carbon atoms, attached in position 1 or 3 with methyl radicals in positions 1 and 3, e.g. theophylline
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/08—Drugs for disorders of the alimentary tract or the digestive system for nausea, cinetosis or vertigo; Antiemetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/20—Hypnotics; Sedatives

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Anesthesiology (AREA)
  • Pain & Pain Management (AREA)
  • Hospice & Palliative Care (AREA)
  • Otolaryngology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Indole Compounds (AREA)
NO853856A 1984-10-01 1985-09-30 Analogifremgangsmaate for fremstilling av 1h-indol-3-yl inneholdende 1,3-di-metyl-1h-purin-2,6-dioner. NO162069C (no)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US06/656,561 US4548939A (en) 1984-10-01 1984-10-01 1H-Indol-3-yl containing 1,3-dimethyl-1H-purine-2,6-diones

Publications (3)

Publication Number Publication Date
NO853856L true NO853856L (no) 1986-04-02
NO162069B NO162069B (no) 1989-07-24
NO162069C NO162069C (no) 1989-11-01

Family

ID=24633577

Family Applications (1)

Application Number Title Priority Date Filing Date
NO853856A NO162069C (no) 1984-10-01 1985-09-30 Analogifremgangsmaate for fremstilling av 1h-indol-3-yl inneholdende 1,3-di-metyl-1h-purin-2,6-dioner.

Country Status (17)

Country Link
US (1) US4548939A (no)
EP (1) EP0177087B1 (no)
JP (1) JPH0653742B2 (no)
CN (1) CN1011311B (no)
AT (1) ATE60604T1 (no)
AU (1) AU576386B2 (no)
CA (1) CA1262348A (no)
DE (1) DE3581577D1 (no)
DK (1) DK163996C (no)
ES (1) ES8609324A1 (no)
FI (1) FI83220C (no)
GR (1) GR852375B (no)
IE (1) IE58747B1 (no)
NO (1) NO162069C (no)
NZ (1) NZ213498A (no)
PT (1) PT81229B (no)
ZA (1) ZA857553B (no)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CH648559A5 (de) * 1981-07-20 1985-03-29 Siegfried Ag Theophyllinderivate und verfahren zu deren herstellung.
US4742057A (en) * 1985-12-05 1988-05-03 Fujisawa Pharmaceutical Co., Ltd. Antiallergic thiazole compounds
US4997841A (en) * 1987-08-13 1991-03-05 Glaxo Group Limited Indole derivatives
GB8719167D0 (en) * 1987-08-13 1987-09-23 Glaxo Group Ltd Chemical compounds
DK733788A (da) * 1988-01-14 1989-07-15 Fujisawa Pharmaceutical Co Indolylpiperidinderivater og fremgangsmaade til fremstilling deraf
GB8819024D0 (en) * 1988-08-10 1988-09-14 Glaxo Group Ltd Chemical compounds
DE3843117A1 (de) * 1988-12-22 1990-06-28 Boehringer Ingelheim Kg Neue xanthinderivate mit adenosin-antagonistischer wirkung
DK292A (da) * 1991-11-29 1992-01-02 Tanisake Kk Middel
DE4414113A1 (de) * 1994-04-22 1995-10-26 Merck Patent Gmbh 3-Indolylpiperidine
EP3663295A1 (en) * 2007-06-22 2020-06-10 Eli Lilly And Co. 2,6-dioxo,-2,3-dihydro-1h-purine compounds useful for treating disorders related to the activity of the trpa1 channel
WO2009140517A1 (en) 2008-05-14 2009-11-19 Hydra Biosciences, Inc. Compounds and compositions for treating chemical warfare agent-induced injuries
US8318728B2 (en) 2008-05-14 2012-11-27 Hydra Biosciences, Inc. Compounds and compositions for treating chemical warfare agent-induced injuries

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2322470A1 (de) * 1973-05-04 1974-11-21 Boehringer Sohn Ingelheim Neue indolyl-piperidino-(bzw. 1,2,5,6tetrahydro-pyridyl-)butyrophenone und verfahren zu ihrer herstellung
FR2334358A1 (fr) * 1975-12-12 1977-07-08 Sogeras Nouveaux medicaments derives de l'indole
FR2362628A1 (fr) * 1976-08-26 1978-03-24 Roussel Uclaf Nouveaux derives du piperidyl-indole et leurs sels, procede de preparation et application a titre de medicaments
EP0011399A1 (en) * 1978-11-11 1980-05-28 FISONS plc N-substituted theophyllines, processes for their preparation and pharmaceutical compositions containing them
DE2922159A1 (de) * 1979-05-31 1980-12-04 Boehringer Mannheim Gmbh Neue xanthin-derivate, verfahren zu ihrer herstellung und diese verbindungen enthaltende arzneimittel
US4342870A (en) * 1980-03-28 1982-08-03 Janssen Pharmaceutica N.V. Novel 3-(1-piperidinylalkyl)-4H-pyrido[1,2-a]pyrimidin-4-one derivatives
US4426383A (en) * 1980-09-04 1984-01-17 Eisai Co., Ltd. Theophylline and theobromine derivatives
US4359468A (en) * 1981-02-25 1982-11-16 Boehringer Ingelheim Ltd. Antiallergic N-[4-(indolyl)-piperidino-alkyl]-benzimidazolones
US4443451A (en) * 1981-07-15 1984-04-17 Janssen Pharmaceutica N.V. Bicyclic pyrimidin-5-one derivatives
CH648559A5 (de) * 1981-07-20 1985-03-29 Siegfried Ag Theophyllinderivate und verfahren zu deren herstellung.

Also Published As

Publication number Publication date
EP0177087A3 (en) 1986-06-11
JPS6187681A (ja) 1986-05-06
CN85105804A (zh) 1986-10-22
DK444085A (da) 1986-04-02
DE3581577D1 (de) 1991-03-07
ATE60604T1 (de) 1991-02-15
IE852403L (en) 1986-04-01
PT81229B (pt) 1987-11-30
FI853763L (fi) 1986-04-02
JPH0653742B2 (ja) 1994-07-20
AU576386B2 (en) 1988-08-25
ZA857553B (en) 1987-05-27
DK163996C (da) 1992-09-21
DK444085D0 (da) 1985-09-30
GR852375B (no) 1986-01-31
ES8609324A1 (es) 1986-07-16
PT81229A (en) 1985-11-01
FI853763A0 (fi) 1985-09-30
NO162069C (no) 1989-11-01
NZ213498A (en) 1988-04-29
FI83220C (fi) 1991-06-10
EP0177087B1 (en) 1991-01-30
DK163996B (da) 1992-04-27
FI83220B (fi) 1991-02-28
EP0177087A2 (en) 1986-04-09
AU4812485A (en) 1986-04-10
CA1262348A (en) 1989-10-17
US4548939A (en) 1985-10-22
NO162069B (no) 1989-07-24
IE58747B1 (en) 1993-11-03
CN1011311B (zh) 1991-01-23
ES547447A0 (es) 1986-07-16

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