DK3227675T3 - Activin-actrii-antagonister og anvendelser til behandling af myelodysplastisk syndrom - Google Patents

Activin-actrii-antagonister og anvendelser til behandling af myelodysplastisk syndrom Download PDF

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Publication number
DK3227675T3
DK3227675T3 DK15865213.1T DK15865213T DK3227675T3 DK 3227675 T3 DK3227675 T3 DK 3227675T3 DK 15865213 T DK15865213 T DK 15865213T DK 3227675 T3 DK3227675 T3 DK 3227675T3
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Prior art keywords
activin
treatment
myelodysplastic syndrome
actrii antagonists
actrii
Prior art date
Application number
DK15865213.1T
Other languages
English (en)
Inventor
Kenneth M Attie
Christopher Rovaldi
Abderrahmane Laadem
Original Assignee
Celgene Corp
Acceleron Pharma Inc
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Filing date
Publication date
Application filed by Celgene Corp, Acceleron Pharma Inc filed Critical Celgene Corp
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Publication of DK3227675T3 publication Critical patent/DK3227675T3/da

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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/177—Receptors; Cell surface antigens; Cell surface determinants
    • A61K38/179—Receptors; Cell surface antigens; Cell surface determinants for growth factors; for growth regulators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/02—Antineoplastic agents specific for leukemia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/06—Antianaemics
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
    • C07K14/71—Receptors; Cell surface antigens; Cell surface determinants for growth factors; for growth regulators
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/483—Physical analysis of biological material
    • G01N33/487—Physical analysis of biological material of liquid biological material
    • G01N33/49—Blood
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C07K2319/30—Non-immunoglobulin-derived peptide or protein having an immunoglobulin constant or Fc region, or a fragment thereof, attached thereto
DK15865213.1T 2014-12-03 2015-12-03 Activin-actrii-antagonister og anvendelser til behandling af myelodysplastisk syndrom DK3227675T3 (da)

Applications Claiming Priority (6)

Application Number Priority Date Filing Date Title
US201462086977P 2014-12-03 2014-12-03
US201462088478P 2014-12-05 2014-12-05
US201562153872P 2015-04-28 2015-04-28
US201562173782P 2015-06-10 2015-06-10
US201562218728P 2015-09-15 2015-09-15
PCT/US2015/063595 WO2016090077A1 (en) 2014-12-03 2015-12-03 Activin-actrii antagonists and uses for treating anemia

Publications (1)

Publication Number Publication Date
DK3227675T3 true DK3227675T3 (da) 2023-05-30

Family

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DK15865213.1T DK3227675T3 (da) 2014-12-03 2015-12-03 Activin-actrii-antagonister og anvendelser til behandling af myelodysplastisk syndrom

Country Status (24)

Country Link
US (1) US11471510B2 (da)
EP (2) EP4233889A3 (da)
JP (2) JP2018501307A (da)
KR (1) KR102556991B1 (da)
CN (2) CN114675039A (da)
AU (2) AU2015358469B2 (da)
BR (1) BR112017011722A2 (da)
CA (1) CA2969572A1 (da)
CY (1) CY1126033T1 (da)
DK (1) DK3227675T3 (da)
ES (1) ES2946160T3 (da)
FI (1) FI3227675T3 (da)
HK (2) HK1245397A1 (da)
HR (1) HRP20230504T1 (da)
HU (1) HUE062189T2 (da)
IL (1) IL252631B1 (da)
LT (1) LT3227675T (da)
MD (1) MD4801C1 (da)
PL (1) PL3227675T3 (da)
PT (1) PT3227675T (da)
RS (1) RS64214B1 (da)
SI (1) SI3227675T1 (da)
TW (2) TWI773117B (da)
WO (1) WO2016090077A1 (da)

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WO2019213016A1 (en) * 2018-04-30 2019-11-07 The Children's Hospital Of Philadelphia Methods of improving anemias by combining agents
JP2022509525A (ja) * 2018-10-31 2022-01-20 セルジーン コーポレイション 環状鉄芽球が見られる対象における非常に低リスク、低リスクまたは中程度のリスクの骨髄異形成症候群による貧血の、アクチビン－ａｃｔｒｉｉリガンドトラップを用いた治療
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