DK3140314T3 - Kaloriefrit sødestof - Google Patents

Kaloriefrit sødestof

Info

Publication number
DK3140314T3
DK3140314T3 DK15789509.5T DK15789509T DK3140314T3 DK 3140314 T3 DK3140314 T3 DK 3140314T3 DK 15789509 T DK15789509 T DK 15789509T DK 3140314 T3 DK3140314 T3 DK 3140314T3
Authority
DK
Denmark
Prior art keywords
caloric
free sweet
sweet
free
Prior art date
Application number
DK15789509.5T
Other languages
Danish (da)
English (en)
Inventor
Guohong Mao
Venkata Sai Prakash Chaturvedula
Xiaodan Yu
Original Assignee
Conagen Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Conagen Inc filed Critical Conagen Inc
Application granted granted Critical
Publication of DK3140314T3 publication Critical patent/DK3140314T3/da

Links

Classifications

    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23LFOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES, NOT OTHERWISE PROVIDED FOR; PREPARATION OR TREATMENT THEREOF
    • A23L27/00Spices; Flavouring agents or condiments; Artificial sweetening agents; Table salts; Dietetic salt substitutes; Preparation or treatment thereof
    • A23L27/30Artificial sweetening agents
    • A23L27/33Artificial sweetening agents containing sugars or derivatives
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07HSUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H15/00Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
    • C07H15/20Carbocyclic rings
    • C07H15/24Condensed ring systems having three or more rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07HSUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H15/00Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
    • C07H15/20Carbocyclic rings
    • C07H15/24Condensed ring systems having three or more rings
    • C07H15/256Polyterpene radicals
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/10Transferases (2.)
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/10Transferases (2.)
    • C12N9/1048Glycosyltransferases (2.4)
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/10Transferases (2.)
    • C12N9/1048Glycosyltransferases (2.4)
    • C12N9/1051Hexosyltransferases (2.4.1)
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/10Transferases (2.)
    • C12N9/1048Glycosyltransferases (2.4)
    • C12N9/1051Hexosyltransferases (2.4.1)
    • C12N9/1062Sucrose synthase (2.4.1.13)
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P19/00Preparation of compounds containing saccharide radicals
    • C12P19/44Preparation of O-glycosides, e.g. glucosides
    • C12P19/56Preparation of O-glycosides, e.g. glucosides having an oxygen atom of the saccharide radical directly bound to a condensed ring system having three or more carbocyclic rings, e.g. daunomycin, adriamycin
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12YENZYMES
    • C12Y204/00Glycosyltransferases (2.4)
    • C12Y204/01Hexosyltransferases (2.4.1)
    • C12Y204/01013Sucrose synthase (2.4.1.13)
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12YENZYMES
    • C12Y204/00Glycosyltransferases (2.4)
    • C12Y204/01Hexosyltransferases (2.4.1)
    • C12Y204/01017Glucuronosyltransferase (2.4.1.17)
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2319/00Fusion polypeptide

Landscapes

  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Biotechnology (AREA)
  • Molecular Biology (AREA)
  • General Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Biomedical Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Nutrition Science (AREA)
  • Food Science & Technology (AREA)
  • Polymers & Plastics (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Seasonings (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Saccharide Compounds (AREA)
DK15789509.5T 2014-05-05 2015-05-05 Kaloriefrit sødestof DK3140314T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US14/269,435 US9522929B2 (en) 2014-05-05 2014-05-05 Non-caloric sweetener
PCT/US2015/029163 WO2015171555A1 (en) 2014-05-05 2015-05-05 A non-caloric sweetener

Publications (1)

Publication Number Publication Date
DK3140314T3 true DK3140314T3 (da) 2019-10-21

Family

ID=54354822

Family Applications (1)

Application Number Title Priority Date Filing Date
DK15789509.5T DK3140314T3 (da) 2014-05-05 2015-05-05 Kaloriefrit sødestof

Country Status (16)

Country Link
US (9) US9522929B2 (cg-RX-API-DMAC7.html)
EP (3) EP4023660A1 (cg-RX-API-DMAC7.html)
JP (1) JP6641357B2 (cg-RX-API-DMAC7.html)
KR (1) KR102378988B1 (cg-RX-API-DMAC7.html)
CN (1) CN106536536B (cg-RX-API-DMAC7.html)
AR (1) AR100277A1 (cg-RX-API-DMAC7.html)
AU (1) AU2015256232B2 (cg-RX-API-DMAC7.html)
BR (1) BR112016025147B1 (cg-RX-API-DMAC7.html)
CA (1) CA2982075A1 (cg-RX-API-DMAC7.html)
DK (1) DK3140314T3 (cg-RX-API-DMAC7.html)
ES (1) ES2750373T3 (cg-RX-API-DMAC7.html)
HU (1) HUE045937T2 (cg-RX-API-DMAC7.html)
MX (1) MX367883B (cg-RX-API-DMAC7.html)
NZ (1) NZ725866A (cg-RX-API-DMAC7.html)
WO (1) WO2015171555A1 (cg-RX-API-DMAC7.html)
ZA (1) ZA201607592B (cg-RX-API-DMAC7.html)

Families Citing this family (34)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2016049315A1 (en) 2014-09-26 2016-03-31 Purecircle Usa Inc. Stevia composition, production method and uses
US9752174B2 (en) 2013-05-28 2017-09-05 Purecircle Sdn Bhd High-purity steviol glycosides
US9522929B2 (en) 2014-05-05 2016-12-20 Conagen Inc. Non-caloric sweetener
BR112017005656A2 (pt) 2014-09-19 2018-07-31 Purecircle Sdn Bhd glicosídeos de esteviol de alta pureza
DK3201351T3 (da) 2014-10-03 2021-02-22 Conagen Inc Kaloriefrie sødestoffer og fremgangsmåder til syntetisering
US10711024B2 (en) 2014-12-17 2020-07-14 Cargill, Incorporated Steviol glycoside compounds, compositions for oral ingestion or use, and method for enhancing steviol glycoside solubility
WO2016156616A1 (en) 2015-04-03 2016-10-06 Dsm Ip Assets B.V. Steviol glycosides
BR112017022019A2 (pt) 2015-04-14 2018-07-31 Conagen Inc. produção de adoçantes não calóricos por meio da utilização de catalisadores de células inteiras modificadas
US10494397B2 (en) * 2016-07-15 2019-12-03 Pepsico, Inc. Rebaudioside analogs
BR112019007504B1 (pt) 2016-10-14 2023-05-09 Conagen Inc Método de preparação de uma composição de glicosídeo de esteviol
MX2019004630A (es) * 2016-10-21 2019-07-15 Pepsico Inc Metodo para preparar rebaudiosido j usando el metodo enzimatico.
AU2016427130B2 (en) 2016-10-21 2022-08-18 Pepsico, Inc. Method for preparing rebaudioside N using enzymatic method
KR101997597B1 (ko) * 2016-11-17 2019-07-08 서울대학교산학협력단 변형 류코노스톡속 균주를 이용한 스테비오사이드 배당체의 합성 방법 및 이에 의하여 제조된 신규한 스테비오사이드 배당체
WO2018093196A1 (ko) * 2016-11-17 2018-05-24 서울대학교산학협력단 변형 류코노스톡속 균주를 이용한 스테비오사이드 배당체의 합성 방법 및 이에 의하여 제조된 신규한 스테비오사이드 배당체
CN110914445B (zh) 2017-02-03 2024-08-27 泰莱解决方案美国有限责任公司 工程化糖基转移酶和甜菊醇糖苷葡糖基化方法
AU2017402700A1 (en) * 2017-03-06 2019-10-17 Conagen Inc. Biosynthetic production of steviol glycoside rebaudioside D4 from rebaudioside E
AU2018294258A1 (en) 2017-06-30 2020-02-06 Conagen Inc. Hydrolysis of steviol glycosides by beta-glucosidase
CN109423486B (zh) * 2017-08-29 2022-02-25 中国科学院分子植物科学卓越创新中心 新型udp-糖基转移酶及其应用
CN107446874B (zh) * 2017-09-25 2020-07-28 四川盈嘉合生科技有限公司 重组大肠杆菌及其在合成莱鲍迪苷d中的用途
CN111868252B (zh) 2018-03-12 2025-06-03 科纳根公司 甜菊糖苷莱苞迪苷j和莱苞迪苷n的生物合成生产
WO2019100676A1 (zh) * 2018-05-25 2019-05-31 邦泰生物工程(深圳)有限公司 一种酶改质甜菊糖的制备方法和制备用酶及应用
JP7584401B2 (ja) 2018-07-30 2024-11-15 テイト アンド ライル ソリューションズ ユー・エス・エー エル・エル・シー 操作されたグリコシルトランスフェラーゼおよびステビオールグリコシドのグルコシル化方法
EP3781583A1 (en) * 2018-09-29 2021-02-24 Firmenich SA Terpene glycoside derivatives and uses thereof
WO2020097922A1 (zh) * 2018-11-16 2020-05-22 邦泰生物工程(深圳)有限公司 一种udp-葡萄糖基转移酶突变体、其应用及其制备莱鲍迪苷d的方法
CN113474464B (zh) * 2018-12-12 2025-06-10 科纳根公司 变体甜菊醇糖苷的生物合成生产
CN109750072B (zh) * 2019-01-31 2022-04-19 南京工业大学 一种酶法制备莱鲍迪苷e的方法
WO2020205685A1 (en) * 2019-03-29 2020-10-08 Conagen Inc. Biosynthetic production of udp-rhamnose
CN110878288B (zh) * 2019-12-09 2020-12-29 安徽农业大学 多肽、核酸及其在合成橙花叔醇糖苷上的应用
CN111378630A (zh) * 2020-04-09 2020-07-07 北京农学院 一种融合蛋白及其高效表达方法与应用
CN114045273B (zh) * 2021-11-15 2022-07-22 四川大学 糖基转移酶OsUGT91C1突变体及其应用
JP2025500510A (ja) * 2021-12-24 2025-01-09 サムヤン コーポレイション 糖転移酵素変異体、およびこれを利用したステビオール配糖体の製造方法
US12446605B2 (en) 2022-03-23 2025-10-21 Sweegen, Inc. Sweeteners
CN115433702A (zh) * 2022-08-23 2022-12-06 江南大学 一种利用糖基转移酶高效生物合成莱鲍迪苷d2的方法
CN117070487B (zh) * 2023-03-27 2024-12-24 浙江大学 茶树芦丁:尿苷二磷酸葡萄糖基转移酶基因及其应用

Family Cites Families (29)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH04149191A (ja) * 1990-10-09 1992-05-22 Nakano Vinegar Co Ltd ステビオサイド糖転移化合物及びその製造方法
WO2002010210A2 (en) 2001-08-28 2002-02-07 Bayer Cropscience Ag Polypeptides for identifying herbicidally active compounds
US20090183270A1 (en) 2002-10-02 2009-07-16 Adams Thomas R Transgenic plants with enhanced agronomic traits
US20080148432A1 (en) 2005-12-21 2008-06-19 Mark Scott Abad Transgenic plants with enhanced agronomic traits
US9107436B2 (en) 2011-02-17 2015-08-18 Purecircle Sdn Bhd Glucosylated steviol glycoside as a flavor modifier
MX2012002749A (es) 2009-09-04 2012-07-04 Redpoint Bio Corp Aumentadores de dulzura incluyendo rebaudiosido a o d.
US8524785B2 (en) 2009-09-04 2013-09-03 International Flavors And Fragrances Inc. Methods for using rebaudioside C as a flavor enhancer
AU2011213602B2 (en) * 2010-02-08 2016-06-23 The Coca-Cola Company Solubility enhanced terpene glycoside(s)
US9795156B2 (en) 2011-03-17 2017-10-24 E.P.C (Beijing) Plant Pharmaceutical Technology Co., Ltd Rebaudioside B and derivatives
SG10201606567TA (en) * 2011-08-08 2016-10-28 Evolva Sa Recombinant production of steviol glycosides
EP2793615A4 (en) 2011-12-20 2016-07-20 Cargill Inc MIXTURE WITH LOW MONATIN AND REBAUDIOSIDE A CONTENT
FR2984743B1 (fr) 2011-12-23 2014-08-22 Oreal Utilisation cosmetique du steviol, d'un derive glycoside du steviol, ou un de leurs isomeres pour stimuler, restaurer ou reguler le metabolisme des cellules de la peau et des semi-muqueuses.
FR2984742A1 (fr) 2011-12-23 2013-06-28 Oreal Utilisation de steviol, d'un derive glycoside du steviol, ou d'un de leurs isomeres, pour prevenir, reduire et/ou traiter une alteration du teint de la peau.
DK2806754T3 (en) 2012-01-23 2019-02-18 Dsm Ip Assets Bv Diterpene PREPARATION
CN102559528B (zh) * 2012-02-09 2013-08-21 南京工业大学 一种产甜叶菊糖基转移酶ugt76g1的基因工程菌及其应用
CN110358795B (zh) 2012-05-22 2024-12-03 谱赛科有限责任公司 高纯度的甜菊醇糖苷
US9752174B2 (en) 2013-05-28 2017-09-05 Purecircle Sdn Bhd High-purity steviol glycosides
CN107613571B (zh) 2012-07-18 2021-05-18 华为技术有限公司 一种数据连接管理的方法、装置及系统
CN103570723B (zh) 2012-07-27 2016-07-13 广西梧州制药(集团)股份有限公司 吡唑并嘧啶衍生物及其制备方法和在药物制备中的用途
CN102766667B (zh) * 2012-08-14 2014-06-11 成都南诺格生物科技有限责任公司 甜菊苷转化为莱鲍迪苷e的方法
CN105051195B (zh) * 2013-02-06 2019-09-06 埃沃尔瓦公司 用于提高莱鲍迪苷d和莱鲍迪苷m之产生的方法
KR101404728B1 (ko) 2013-02-28 2014-06-09 씨제이제일제당 (주) 스테비오사이드로부터 리바우디오사이드 a를 제조하는 방법
CN103397064B (zh) * 2013-08-14 2015-04-15 苏州汉酶生物技术有限公司 一种酶法制备瑞鲍迪甙m的方法
CN106103729B (zh) 2013-11-01 2020-07-07 科纳根公司 甜菊醇糖苷的重组制备
US9522929B2 (en) 2014-05-05 2016-12-20 Conagen Inc. Non-caloric sweetener
CN104232496B (zh) 2014-09-18 2017-06-06 广州康琳奈生物科技有限公司 一种重组毕赤酵母工程菌及其在合成莱鲍迪苷a中的应用
DK3201351T3 (da) 2014-10-03 2021-02-22 Conagen Inc Kaloriefrie sødestoffer og fremgangsmåder til syntetisering
BR112017022019A2 (pt) 2015-04-14 2018-07-31 Conagen Inc. produção de adoçantes não calóricos por meio da utilização de catalisadores de células inteiras modificadas
WO2017122227A1 (en) 2016-01-13 2017-07-20 Shri Amm Murugappa Chettiar Research Centre (Mcrc) Mrsa and vrsa resistant textile materials

Also Published As

Publication number Publication date
US20160208303A1 (en) 2016-07-21
BR112016025147A2 (pt) 2017-12-12
EP3140314A4 (en) 2017-10-18
KR20160147994A (ko) 2016-12-23
EP3140314A1 (en) 2017-03-15
US9765104B2 (en) 2017-09-19
US10597418B2 (en) 2020-03-24
EP4023660A1 (en) 2022-07-06
US9522929B2 (en) 2016-12-20
HUE045937T2 (hu) 2020-01-28
NZ725866A (en) 2022-11-25
US20180051049A1 (en) 2018-02-22
CA2982075A1 (en) 2015-11-12
US10941174B2 (en) 2021-03-09
AU2015256232A1 (en) 2016-11-24
EP3418288A1 (en) 2018-12-26
US20150315623A1 (en) 2015-11-05
US9527880B2 (en) 2016-12-27
US20160208225A1 (en) 2016-07-21
US10654881B2 (en) 2020-05-19
CN106536536A8 (zh) 2017-07-07
AU2015256232B2 (en) 2019-09-26
WO2015171555A1 (en) 2015-11-12
JP2017519812A (ja) 2017-07-20
BR112016025147B1 (pt) 2021-11-03
US20180009835A1 (en) 2018-01-11
US9988414B2 (en) 2018-06-05
KR102378988B1 (ko) 2022-03-28
EP3140314B1 (en) 2019-07-31
US20200361978A1 (en) 2020-11-19
ES2750373T3 (es) 2020-03-25
US20180037600A1 (en) 2018-02-08
CN106536536A (zh) 2017-03-22
CN106536536B (zh) 2019-12-06
ZA201607592B (en) 2019-02-27
AR100277A1 (es) 2016-09-21
US20180244709A1 (en) 2018-08-30
US10138263B2 (en) 2018-11-27
JP6641357B2 (ja) 2020-02-05
US10450339B2 (en) 2019-10-22
MX2016014506A (es) 2017-02-23
EP3418288B1 (en) 2022-01-19
MX367883B (es) 2019-09-10
US20160207954A1 (en) 2016-07-21

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