DK3028716T3 - Komplementhæmning til forbedret nerveregeneration - Google Patents

Komplementhæmning til forbedret nerveregeneration Download PDF

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Publication number
DK3028716T3
DK3028716T3 DK15187453.4T DK15187453T DK3028716T3 DK 3028716 T3 DK3028716 T3 DK 3028716T3 DK 15187453 T DK15187453 T DK 15187453T DK 3028716 T3 DK3028716 T3 DK 3028716T3
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Denmark
Prior art keywords
generation
complementary inhibition
nervous
improved nervous
improved
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DK15187453.4T
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English (en)
Inventor
Frank Baas
Valeria Ramaglia
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Regenesance B V
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    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/40Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against enzymes
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/185Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19Carboxylic acids, e.g. valproic acid
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/21Esters, e.g. nitroglycerine, selenocyanates
    • A61K31/215Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
    • A61K31/235Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids having an aromatic ring attached to a carboxyl group
    • A61K31/24Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids having an aromatic ring attached to a carboxyl group having an amino or nitro group
    • A61K31/245Amino benzoic acid types, e.g. procaine, novocaine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/70Carbohydrates; Sugars; Derivatives thereof
    • A61K31/715Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
    • A61K31/726Glycosaminoglycans, i.e. mucopolysaccharides
    • A61K31/727Heparin; Heparan
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/177Receptors; Cell surface antigens; Cell surface determinants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/02Drugs for disorders of the nervous system for peripheral neuropathies
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/28Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/11DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C12N15/113Non-coding nucleic acids modulating the expression of genes, e.g. antisense oligonucleotides; Antisense DNA or RNA; Triplex- forming oligonucleotides; Catalytic nucleic acids, e.g. ribozymes; Nucleic acids used in co-suppression or gene silencing
    • C12N15/1137Non-coding nucleic acids modulating the expression of genes, e.g. antisense oligonucleotides; Antisense DNA or RNA; Triplex- forming oligonucleotides; Catalytic nucleic acids, e.g. ribozymes; Nucleic acids used in co-suppression or gene silencing against enzymes
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/505Medicinal preparations containing antigens or antibodies comprising antibodies

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Epidemiology (AREA)
  • Biomedical Technology (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Zoology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Immunology (AREA)
  • Neurosurgery (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Neurology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Wood Science & Technology (AREA)
  • Dermatology (AREA)
  • Emergency Medicine (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Cell Biology (AREA)
  • Plant Pathology (AREA)
  • Physics & Mathematics (AREA)
  • Virology (AREA)
  • Microbiology (AREA)
  • Psychiatry (AREA)
  • Hospice & Palliative Care (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
DK15187453.4T 2006-10-10 2007-10-10 Komplementhæmning til forbedret nerveregeneration DK3028716T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US85027706P 2006-10-10 2006-10-10
EP13181901.3A EP2698166B1 (en) 2006-10-10 2007-10-10 Complement inhibition for improved nerve regeneration

Publications (1)

Publication Number Publication Date
DK3028716T3 true DK3028716T3 (da) 2020-11-23

Family

ID=38857887

Family Applications (2)

Application Number Title Priority Date Filing Date
DK15187453.4T DK3028716T3 (da) 2006-10-10 2007-10-10 Komplementhæmning til forbedret nerveregeneration
DK13181901.3T DK2698166T3 (da) 2006-10-10 2007-10-10 Komplementærhæmning for bedre nerveregeneration

Family Applications After (1)

Application Number Title Priority Date Filing Date
DK13181901.3T DK2698166T3 (da) 2006-10-10 2007-10-10 Komplementærhæmning for bedre nerveregeneration

Country Status (16)

Country Link
US (4) US8703136B2 (da)
EP (4) EP3804755A1 (da)
JP (2) JP2010505946A (da)
AU (1) AU2007307375B2 (da)
CA (3) CA3154415A1 (da)
CY (1) CY1123734T1 (da)
DK (2) DK3028716T3 (da)
ES (2) ES2831325T3 (da)
HK (2) HK1194688A1 (da)
HU (2) HUE026042T2 (da)
LT (1) LT3028716T (da)
NZ (1) NZ576195A (da)
PL (2) PL2698166T3 (da)
PT (2) PT3028716T (da)
SI (2) SI3028716T1 (da)
WO (1) WO2008044928A1 (da)

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WO2011105901A2 (en) 2010-02-23 2011-09-01 Academisch Ziekenhuis Bij De Universiteit Van Amsterdam Antagonists of complement component 9 (c9) and uses thereof
WO2011105900A2 (en) 2010-02-23 2011-09-01 Academisch Ziekenhuis Bij De Universiteit Van Amsterdam Antagonists of complement component 8-alpha (c8-alpha) and uses thereof
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CA2666466A1 (en) 2008-04-17
HUE052964T2 (hu) 2021-06-28
JP2013189470A (ja) 2013-09-26
EP2698166A2 (en) 2014-02-19
PL2698166T3 (pl) 2016-03-31
EP2073898A1 (en) 2009-07-01
CA2666466C (en) 2017-11-14
SI3028716T1 (sl) 2021-01-29
HUE026042T2 (en) 2016-05-30
HK1225620A1 (zh) 2017-09-15
AU2007307375B2 (en) 2013-11-28
US20180022824A1 (en) 2018-01-25
EP3028716A1 (en) 2016-06-08
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DK2698166T3 (da) 2015-12-21
US20140255395A1 (en) 2014-09-11
NZ576195A (en) 2012-04-27
EP3804755A1 (en) 2021-04-14
PL3028716T3 (pl) 2021-03-08
WO2008044928A1 (en) 2008-04-17
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HK1194688A1 (zh) 2014-10-24
ES2831325T3 (es) 2021-06-08
AU2007307375A1 (en) 2008-04-17
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SI2698166T1 (sl) 2016-02-29
EP2698166A3 (en) 2014-04-02
CA2980614A1 (en) 2008-04-17
EP2698166B1 (en) 2015-09-30
US20220227884A1 (en) 2022-07-21
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PT3028716T (pt) 2020-11-23

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