ES2171465T3 - Inhibidor de la esterasa de c1 para reducir lesiones de miocardio durante un infarto de miocardio agudo. - Google Patents
Inhibidor de la esterasa de c1 para reducir lesiones de miocardio durante un infarto de miocardio agudo.Info
- Publication number
- ES2171465T3 ES2171465T3 ES94929047T ES94929047T ES2171465T3 ES 2171465 T3 ES2171465 T3 ES 2171465T3 ES 94929047 T ES94929047 T ES 94929047T ES 94929047 T ES94929047 T ES 94929047T ES 2171465 T3 ES2171465 T3 ES 2171465T3
- Authority
- ES
- Spain
- Prior art keywords
- esterase inhibitor
- miocard
- pct
- myocardial infarction
- acute myocardial
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/55—Protease inhibitors
- A61K38/57—Protease inhibitors from animals; from humans
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/08—Vasodilators for multiple indications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Public Health (AREA)
- Engineering & Computer Science (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Immunology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Cardiology (AREA)
- Epidemiology (AREA)
- Zoology (AREA)
- Heart & Thoracic Surgery (AREA)
- Gastroenterology & Hepatology (AREA)
- Urology & Nephrology (AREA)
- Pain & Pain Management (AREA)
- Rheumatology (AREA)
- Vascular Medicine (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Electrotherapy Devices (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
UN METODO DE TRATAMIENTO TERAPEUTICO O PROFILACTICO DE LA INFARTACION MIOCARDICA AGUDA, QUE CONSISTE EN ADMINISTRAR UN INHIBIDOR DE LA ESTERASA C1 EXOGENO, POR SI SOLO O COMBINADO CON OTROS FARMACOS, A UN PACIENTE CON INFARTACION MIOCARDICA AGUDO O A UN PACIENTE CON RIESGO DE PADECER UN INFARTO DE MIOCARDIO AGUDO. EL TRATAMIENTO INHIBE LA REACCION INFLAMATORIA, Y DE MANERA MAS ESPECIFICA LA ACTIVACION DEL SISTEMA COMPLEMENTO, QUE TIENE LUGAR DURANTE UNA INFARTACION MIOCARDICA AGUDO. EL INHIBIDOR DE LA ESTERASA C1 PUEDE INCLUIR UN INHIBIDOR DE LA ESTERASA C1 PURIFICADO A PARTIR DE UN PLASMA O DE OTROS MATERIALES BIOLOGICOS, O UN INHIBIDOR DE LA ESTERASA C1 RECOMBINANTE, O ESTRUCTURAS RECOMBINANTES DE OTROS INHIBIDORES QUE POSEEN UNA ESPECIFICIDAD SIMILAR A LA DEL INHIBIDOR DE LA ESTERASA C1.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
EP93202572 | 1993-09-01 |
Publications (1)
Publication Number | Publication Date |
---|---|
ES2171465T3 true ES2171465T3 (es) | 2002-09-16 |
Family
ID=8214075
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES94929047T Expired - Lifetime ES2171465T3 (es) | 1993-09-01 | 1994-08-31 | Inhibidor de la esterasa de c1 para reducir lesiones de miocardio durante un infarto de miocardio agudo. |
Country Status (10)
Country | Link |
---|---|
US (1) | US6090777A (es) |
EP (1) | EP0716611B1 (es) |
JP (2) | JP4077030B2 (es) |
AT (1) | ATE212859T1 (es) |
AU (1) | AU678064B2 (es) |
DE (1) | DE69429816T2 (es) |
DK (1) | DK0716611T3 (es) |
ES (1) | ES2171465T3 (es) |
PT (1) | PT716611E (es) |
WO (1) | WO1995006479A1 (es) |
Families Citing this family (16)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE19829014A1 (de) * | 1998-06-30 | 2000-01-05 | Centeon Pharma Gmbh | Modifizierter C1-Esterase-Inhibitor zur Blockierung der Infektiosität von HIV |
US7008645B2 (en) * | 1998-07-14 | 2006-03-07 | Yissum Research Development Company Of The Hebrew University Of Jerusalem | Method of inhibiting restenosis using bisphosphonates |
CA2426115A1 (en) * | 2003-04-18 | 2004-10-18 | Victor Gurewich | Methods, devices, and compositions for lysis of occlusive blood clots while sparing wound sealing clots |
US10517883B2 (en) * | 2003-06-27 | 2019-12-31 | Zuli Holdings Ltd. | Method of treating acute myocardial infarction |
US20060051407A1 (en) * | 2003-06-27 | 2006-03-09 | Yoram Richter | Method of treating ischemia-reperfusion injury |
US20070196367A1 (en) * | 2006-02-22 | 2007-08-23 | Valentin Dinu | Methods of preventing and treating Alzheimer's disease, age related macular degeneration and other diseases involving extra-cellular debris through the inhibition of the complement system |
US20090010916A1 (en) * | 2006-06-22 | 2009-01-08 | Victor Gurewich | C-1 Inhibitor prevents non-specific plasminogen activation by a prourokinase mutant without impeding fibrin-specific fibrinolysis |
US8703136B2 (en) | 2006-10-10 | 2014-04-22 | Regenesance B.V. | Complement inhibition for improved nerve regeneration |
CA2889170C (en) | 2012-10-25 | 2021-09-07 | True North Therapeutics, Inc. | Anti-complement c1s antibodies and uses thereof |
RS63212B1 (sr) | 2012-11-02 | 2022-06-30 | Bioverativ Usa Inc | Antikomplementna c1s antitela i njihove primene |
ES2609070T3 (es) * | 2013-02-28 | 2017-04-18 | Csl Behring Gmbh | Agente terapéutico para el embolismo de líquido amniótico |
KR102403299B1 (ko) * | 2013-03-08 | 2022-06-03 | 체에스엘 베링 게엠베하 | 원격 허혈-재관류 손상의 치료 및 예방 |
US9993427B2 (en) | 2013-03-14 | 2018-06-12 | Biorest Ltd. | Liposome formulation and manufacture |
EP2968434B1 (en) * | 2013-03-15 | 2017-06-28 | Shire Viropharma Incorporated | C1-inh compositions for use in the prevention and treatment of hereditary angioedema (hae). |
KR20160026905A (ko) * | 2013-06-28 | 2016-03-09 | 체에스엘 베링 게엠베하 | 인자 xii 억제제 및 c1-억제제를 이용한 병용 치료요법 |
EP4212175A1 (en) | 2015-04-06 | 2023-07-19 | Bioverativ USA Inc. | Humanized anti-c1s antibodies and methods of use thereof |
Family Cites Families (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE3228502A1 (de) * | 1982-07-30 | 1984-02-02 | Behringwerke Ag, 3550 Marburg | Verfahren zur herstellung des c1-inaktivators und seine verwendung |
FR2601034B1 (fr) * | 1986-07-03 | 1989-11-17 | Pasteur Institut | Inhibiteur de l'activite de la c1-esterase plasmatique (c1-inhibiteur) et d'autres enzymes proteolytiques du groupe des proteases a serine, son procede de preparation, acides nucleiques codant pour cet inhibiteur, methodes de detection d'affections correlees aux defauts dudit inhibiteur a l'aide d'anticorps ou de sondes nucleotidiques et medicaments contenant ledit inhibiteur de synthese |
EP0497833A1 (en) * | 1989-10-27 | 1992-08-12 | Stichting Centraal Laboratorium van de Bloedtransfusiedienst van het Nederlandse Rode Kruis | C1 inhibitor muteins and uses thereof |
WO1992022320A1 (en) * | 1991-06-14 | 1992-12-23 | Genentech, Inc. | C1 inhibitor variants and treating inflammatory response with c1 inhibitor |
-
1994
- 1994-08-31 DK DK94929047T patent/DK0716611T3/da active
- 1994-08-31 ES ES94929047T patent/ES2171465T3/es not_active Expired - Lifetime
- 1994-08-31 JP JP50804995A patent/JP4077030B2/ja not_active Expired - Lifetime
- 1994-08-31 AT AT94929047T patent/ATE212859T1/de active
- 1994-08-31 AU AU78239/94A patent/AU678064B2/en not_active Expired
- 1994-08-31 US US08/604,933 patent/US6090777A/en not_active Expired - Lifetime
- 1994-08-31 WO PCT/NL1994/000208 patent/WO1995006479A1/en active IP Right Grant
- 1994-08-31 DE DE69429816T patent/DE69429816T2/de not_active Expired - Lifetime
- 1994-08-31 EP EP94929047A patent/EP0716611B1/en not_active Expired - Lifetime
- 1994-08-31 PT PT94929047T patent/PT716611E/pt unknown
-
2007
- 2007-11-21 JP JP2007301371A patent/JP2008056705A/ja active Pending
Also Published As
Publication number | Publication date |
---|---|
DK0716611T3 (da) | 2002-05-21 |
JP2008056705A (ja) | 2008-03-13 |
AU7823994A (en) | 1995-03-22 |
WO1995006479A1 (en) | 1995-03-09 |
US6090777A (en) | 2000-07-18 |
ATE212859T1 (de) | 2002-02-15 |
AU678064B2 (en) | 1997-05-15 |
PT716611E (pt) | 2002-06-28 |
EP0716611B1 (en) | 2002-02-06 |
DE69429816T2 (de) | 2002-09-19 |
EP0716611A1 (en) | 1996-06-19 |
DE69429816D1 (de) | 2002-03-21 |
JPH09501946A (ja) | 1997-02-25 |
JP4077030B2 (ja) | 2008-04-16 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
FG2A | Definitive protection |
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