ATE516043T1 - Verwendung von c1-inhibitor zur prävention von ischämischen reperfusionsschäden - Google Patents
Verwendung von c1-inhibitor zur prävention von ischämischen reperfusionsschädenInfo
- Publication number
- ATE516043T1 ATE516043T1 AT06824316T AT06824316T ATE516043T1 AT E516043 T1 ATE516043 T1 AT E516043T1 AT 06824316 T AT06824316 T AT 06824316T AT 06824316 T AT06824316 T AT 06824316T AT E516043 T1 ATE516043 T1 AT E516043T1
- Authority
- AT
- Austria
- Prior art keywords
- inhibitor
- reperfusion injury
- prevention
- ischemic reperfusion
- reperfusion
- Prior art date
Links
- 239000003112 inhibitor Substances 0.000 title abstract 3
- 230000000302 ischemic effect Effects 0.000 title abstract 3
- 206010063837 Reperfusion injury Diseases 0.000 title abstract 2
- 230000002265 prevention Effects 0.000 title 1
- 230000010410 reperfusion Effects 0.000 abstract 2
- 208000028867 ischemia Diseases 0.000 abstract 1
- 230000000069 prophylactic effect Effects 0.000 abstract 1
- 230000001225 therapeutic effect Effects 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/55—Protease inhibitors
- A61K38/57—Protease inhibitors from animals; from humans
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/12—Drugs for disorders of the urinary system of the kidneys
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P41/00—Drugs used in surgical methods, e.g. surgery adjuvants for preventing adhesion or for vitreum substitution
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- General Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Epidemiology (AREA)
- Immunology (AREA)
- Zoology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Gastroenterology & Hepatology (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Urology & Nephrology (AREA)
- Hematology (AREA)
- Neurosurgery (AREA)
- Neurology (AREA)
- Biomedical Technology (AREA)
- Vascular Medicine (AREA)
- Diabetes (AREA)
- Surgery (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Peptides Or Proteins (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP05112630 | 2005-12-21 | ||
| US76094406P | 2006-01-23 | 2006-01-23 | |
| PCT/NL2006/050321 WO2007073186A2 (en) | 2005-12-21 | 2006-12-19 | Use of c1 inhibitor for the prevention of ischemia-reperfusion injury |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE516043T1 true ATE516043T1 (de) | 2011-07-15 |
Family
ID=38016640
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT06824316T ATE516043T1 (de) | 2005-12-21 | 2006-12-19 | Verwendung von c1-inhibitor zur prävention von ischämischen reperfusionsschäden |
Country Status (15)
| Country | Link |
|---|---|
| US (3) | US8071532B2 (de) |
| EP (2) | EP2380587B1 (de) |
| JP (2) | JP5394748B2 (de) |
| KR (1) | KR101508668B1 (de) |
| AT (1) | ATE516043T1 (de) |
| AU (1) | AU2006327989B2 (de) |
| CA (1) | CA2632400C (de) |
| CY (2) | CY1112452T1 (de) |
| DK (1) | DK2380587T3 (de) |
| HR (2) | HRP20110622T1 (de) |
| IL (2) | IL192180A (de) |
| NZ (1) | NZ568749A (de) |
| PL (2) | PL2380587T3 (de) |
| SI (1) | SI2380587T1 (de) |
| WO (1) | WO2007073186A2 (de) |
Families Citing this family (35)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA2502539A1 (en) * | 2002-10-17 | 2004-04-29 | Pharming Intellectual Property B.V. | Protein modification |
| SI2380587T1 (en) | 2005-12-21 | 2018-03-30 | Pharming Intellectual Property B.V. | Use of a C1 inhibitor to prevent ischemic reperfusion injury |
| NZ576195A (en) * | 2006-10-10 | 2012-04-27 | Az Univ Amsterdam | Complement inhibition for improved nerve regeneration |
| JP5423266B2 (ja) * | 2009-09-14 | 2014-02-19 | 富士電機株式会社 | デジタル制御スイッチング電源装置 |
| ES2646191T3 (es) * | 2011-03-09 | 2017-12-12 | Csl Behring Gmbh | Inhibidores de Factor XII para la administración con procedimientos médicos que comprenden contacto con superficies artificiales |
| EP2497489A1 (de) * | 2011-03-09 | 2012-09-12 | CSL Behring GmbH | Faktor XII-Hemmer zur Behandlung von schleichender Ischämie und Ischämie in anderen Organen |
| ES2714999T3 (es) | 2011-09-24 | 2019-05-31 | Csl Behring Gmbh | Terapia de combinación que usa inmunoglobulina e inhibidor de C1 |
| US10531655B2 (en) | 2011-12-02 | 2020-01-14 | The Regents Of The University Of California | Reperfusion protection solution and uses thereof |
| US9452203B2 (en) | 2011-12-22 | 2016-09-27 | Csl Behring Gmbh | Use of C1-inhibitor for the treatment of secondary edema of the central nervous system |
| WO2014008242A1 (en) * | 2012-07-03 | 2014-01-09 | The Trustees Of Columbia University In The City Of New York | The use of interleukin-11 to protect against ischemia and reperfusion injury |
| CN104870475B (zh) | 2012-10-25 | 2019-11-08 | 美国比奥维拉迪维股份有限公司 | 抗补体C1s抗体和其用途 |
| CA2889197A1 (en) | 2012-11-02 | 2014-05-08 | True North Therapeutics, Inc. | Anti-complement c1s antibodies and uses thereof |
| US10441631B2 (en) | 2013-02-28 | 2019-10-15 | Csl Behring Gmbh | Therapeutic agent for amniotic fluid embolism |
| JP6636334B2 (ja) * | 2013-03-08 | 2020-01-29 | ツェー・エス・エル・ベーリング・ゲー・エム・ベー・ハー | 遠隔虚血再灌流傷害の治療および予防 |
| SMT201700415T1 (it) | 2013-03-15 | 2017-11-15 | Shire Viropharma Inc | Composizioni di c1-inh per l’uso nella prevenzione e nel trattamento dell’angioedema ereditario (hae) |
| US20160166660A1 (en) * | 2013-06-28 | 2016-06-16 | Csl Behring Gmbh | Combination therapy using a factor xii inhibitor and a c-1 inhibitor |
| EP3708226A1 (de) * | 2014-11-03 | 2020-09-16 | Thrombolytic Science, LLC | Verfahren und zusammensetzungen zur sicheren und wirksamen thrombolyse |
| PT3280440T (pt) | 2015-04-06 | 2023-02-14 | Bioverativ Usa Inc | Anticorpos anti-c1s humanizados e métodos de utilização destes |
| WO2016196070A1 (en) | 2015-06-03 | 2016-12-08 | Children's Hospital Medical Center | Compositions and methods for treating neonatal biliary atresia |
| JP7189767B2 (ja) * | 2015-11-19 | 2022-12-14 | 武田薬品工業株式会社 | 組換えヒトｃ１エステラーゼインヒビター及びその使用 |
| EP3493832A1 (de) | 2016-08-05 | 2019-06-12 | CSL Behring GmbH | Pharmazeutische formulierungen von c1-esterasehemmer |
| US20190183991A1 (en) | 2016-08-23 | 2019-06-20 | Csl Behring Gmbh | Method of preventing acute attacks of hereditary angioedema associated with c1 esterase inhibitor deficiency |
| CN116554320A (zh) | 2016-10-12 | 2023-08-08 | 美国比奥维拉迪维股份有限公司 | 抗C1s抗体及其使用方法 |
| WO2018232305A1 (en) | 2017-06-16 | 2018-12-20 | Thrombolytic Science, Llc | Methods and compositions for thrombolysis |
| CA3075686A1 (en) | 2017-09-15 | 2019-03-21 | Cedars-Sinai Medical Center | Methods for improving organ function in organ transplant patients |
| WO2019166572A1 (en) | 2018-02-28 | 2019-09-06 | Pharming Intellectual Property B.V. | Pharmaceutical system for transdermal administration of a c1 -esterase inhibitor |
| KR20210005549A (ko) | 2018-02-28 | 2021-01-14 | 파밍 인텔렉츄얼 프라퍼티 비.브이. | 전자간증의 치료 및 예방 |
| CA3115393A1 (en) | 2018-10-17 | 2020-04-23 | Csl Behring Gmbh | Process for purifying c1-inh |
| AU2020299425A1 (en) | 2019-07-04 | 2022-03-03 | Csl Behring Gmbh | Process for purifying C1-INH |
| KR102191500B1 (ko) | 2020-03-30 | 2020-12-15 | 국립낙동강생물자원관 | 초석잠 추출물을 포함하는 기억력 및 인지기능 개선, 허혈 재관류 손상 예방 및 개선용 조성물 |
| EP3895726A1 (de) * | 2020-04-17 | 2021-10-20 | Pharming Intellectual Property BV | Verwendung von c1-esterase-inhibitoren zur behandlung von akuter atemnot im zusammenhang mit virusinfektionen |
| KR102217607B1 (ko) | 2020-06-01 | 2021-02-18 | 국립낙동강생물자원관 | 석창포 추출물을 포함하는 기억력 및 인지기능 개선, 허혈 재관류 손상 예방 및 개선용 조성물 |
| KR102191452B1 (ko) | 2020-06-30 | 2020-12-15 | 주식회사 에이치비헬스케어 | 곶감 추출물을 포함하는 기억력 및 인지기능 개선, 허혈 재관류 손상 예방 및 개선용 조성물 |
| CN116568327A (zh) | 2020-11-20 | 2023-08-08 | 德国杰特贝林生物制品有限公司 | 治疗抗体介导的排斥反应的方法 |
| US20240342258A1 (en) | 2021-07-09 | 2024-10-17 | Pharming Intellectual Property B.V. | Using c1 esterase inhibitor to treat viral infection-related symptoms |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2000070043A1 (en) | 1999-05-14 | 2000-11-23 | Steffen Thiel | Recombinant human mannan-binding lectin |
| DE122011000002I1 (de) * | 2000-01-31 | 2011-05-05 | Pharming Intellectual Pty Bv | Humaner c1 inhibitor hergestellt in der milch transgener säugetiere |
| US7067713B2 (en) | 2000-01-31 | 2006-06-27 | Pharming Intellectual Property B.V. | C1 Inhibitor produced in the milk of transgenic non-human mammals |
| JP2004100982A (ja) * | 2002-09-05 | 2004-04-02 | Denso Corp | 熱交換器 |
| CA2502539A1 (en) | 2002-10-17 | 2004-04-29 | Pharming Intellectual Property B.V. | Protein modification |
| DK1626736T3 (da) * | 2003-05-16 | 2020-09-28 | Pharming Intellectual Property B V | C1-inhibitor med kort halveringstid til midlertidig behandling |
| SI2380587T1 (en) | 2005-12-21 | 2018-03-30 | Pharming Intellectual Property B.V. | Use of a C1 inhibitor to prevent ischemic reperfusion injury |
-
2006
- 2006-12-19 SI SI200632219T patent/SI2380587T1/en unknown
- 2006-12-19 NZ NZ568749A patent/NZ568749A/en unknown
- 2006-12-19 AT AT06824316T patent/ATE516043T1/de active
- 2006-12-19 AU AU2006327989A patent/AU2006327989B2/en active Active
- 2006-12-19 US US12/158,987 patent/US8071532B2/en active Active
- 2006-12-19 EP EP11172880.4A patent/EP2380587B1/de active Active
- 2006-12-19 CA CA2632400A patent/CA2632400C/en active Active
- 2006-12-19 DK DK11172880.4T patent/DK2380587T3/en active
- 2006-12-19 EP EP06824316A patent/EP1965831B1/de active Active
- 2006-12-19 JP JP2008547134A patent/JP5394748B2/ja not_active Expired - Fee Related
- 2006-12-19 WO PCT/NL2006/050321 patent/WO2007073186A2/en not_active Ceased
- 2006-12-19 HR HR20110622T patent/HRP20110622T1/hr unknown
- 2006-12-19 PL PL11172880T patent/PL2380587T3/pl unknown
- 2006-12-19 PL PL06824316T patent/PL1965831T3/pl unknown
- 2006-12-19 KR KR1020087017880A patent/KR101508668B1/ko active Active
-
2008
- 2008-06-15 IL IL192180A patent/IL192180A/en active IP Right Grant
-
2011
- 2011-10-05 CY CY20111100950T patent/CY1112452T1/el unknown
- 2011-10-11 US US13/271,107 patent/US8415288B2/en active Active
-
2013
- 2013-02-04 JP JP2013019186A patent/JP2013126992A/ja active Pending
- 2013-02-25 US US13/776,529 patent/US9211318B2/en active Active
- 2013-10-17 IL IL228954A patent/IL228954A/en active IP Right Grant
-
2017
- 2017-11-13 HR HRP20171738TT patent/HRP20171738T1/hr unknown
-
2018
- 2018-01-10 CY CY20181100029T patent/CY1119818T1/el unknown
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| UEP | Publication of translation of european patent specification |
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