DK2857404T3 - IMIDAZO [1,2-b] PYRIDAZINE DERIVATIVES AS KINase INHIBITORS - Google Patents

IMIDAZO [1,2-b] PYRIDAZINE DERIVATIVES AS KINase INHIBITORS Download PDF

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Publication number
DK2857404T3
DK2857404T3 DK13801320.6T DK13801320T DK2857404T3 DK 2857404 T3 DK2857404 T3 DK 2857404T3 DK 13801320 T DK13801320 T DK 13801320T DK 2857404 T3 DK2857404 T3 DK 2857404T3
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group
imidazo
phenyl
amino
compound
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DK13801320.6T
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Danish (da)
English (en)
Inventor
Yasuyuki Takeda
Kenji Yoshikawa
Yoshiko Kagoshima
Yuko Yamamoto
Ryoichi Tanaka
Yuichi Tominaga
Masaki Kiga
Yoshito Hamada
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Daiichi Sankyo Co Ltd
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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/02—Antineoplastic agents specific for leukemia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/50—Pyridazines; Hydrogenated pyridazines
    • A61K31/5025—Pyridazines; Hydrogenated pyridazines ortho- or peri-condensed with heterocyclic ring systems

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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Hematology (AREA)
  • Oncology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
DK13801320.6T 2012-06-04 2013-06-03 IMIDAZO [1,2-b] PYRIDAZINE DERIVATIVES AS KINase INHIBITORS DK2857404T3 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP2012127079 2012-06-04
PCT/JP2013/065328 WO2013183578A1 (ja) 2012-06-04 2013-06-03 キナーゼ阻害剤としてのイミダゾ[１，２－ｂ]ピリダジン誘導体

Publications (1)

Publication Number Publication Date
DK2857404T3 true DK2857404T3 (en) 2017-12-04

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ID=49711970

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DK13801320.6T DK2857404T3 (en) 2012-06-04 2013-06-03 IMIDAZO [1,2-b] PYRIDAZINE DERIVATIVES AS KINase INHIBITORS

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Country Link
US (2) US9187489B2 (Direct)
EP (1) EP2857404B1 (Direct)
JP (1) JP5814467B2 (Direct)
KR (1) KR101781255B1 (Direct)
CN (1) CN104520300B (Direct)
AU (1) AU2013272701B2 (Direct)
BR (1) BR112014029851B1 (Direct)
CA (1) CA2874819C (Direct)
CO (1) CO7160119A2 (Direct)
CY (1) CY1119607T1 (Direct)
DK (1) DK2857404T3 (Direct)
ES (1) ES2648228T3 (Direct)
HR (1) HRP20171724T1 (Direct)
HU (1) HUE037221T2 (Direct)
IL (1) IL236075A (Direct)
IN (1) IN2014MN02497A (Direct)
LT (1) LT2857404T (Direct)
MX (1) MX357021B (Direct)
MY (1) MY170326A (Direct)
NO (1) NO2857404T3 (Direct)
NZ (1) NZ702574A (Direct)
PH (1) PH12014502721A1 (Direct)
PL (1) PL2857404T3 (Direct)
PT (1) PT2857404T (Direct)
RS (1) RS56625B1 (Direct)
RU (1) RU2635917C2 (Direct)
SG (1) SG11201408052WA (Direct)
SI (1) SI2857404T1 (Direct)
SM (1) SMT201700539T1 (Direct)
TW (1) TWI585088B (Direct)
WO (1) WO2013183578A1 (Direct)
ZA (1) ZA201408843B (Direct)

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AU2013272701A1 (en) 2015-01-15
IL236075A (en) 2017-10-31
CO7160119A2 (es) 2015-01-15
TW201400486A (zh) 2014-01-01
PH12014502721B1 (en) 2015-02-02
HK1207374A1 (en) 2016-01-29
MY170326A (en) 2019-07-17
AU2013272701A2 (en) 2015-01-22
NZ702574A (en) 2016-07-29
CA2874819C (en) 2017-06-20
HUE037221T2 (hu) 2018-08-28
US20160046639A1 (en) 2016-02-18
IN2014MN02497A (Direct) 2015-07-17
CN104520300B (zh) 2016-12-21
EP2857404B1 (en) 2017-08-23
JPWO2013183578A1 (ja) 2016-01-28
US9751887B2 (en) 2017-09-05
RS56625B1 (sr) 2018-03-30
EP2857404A1 (en) 2015-04-08
US20150051190A1 (en) 2015-02-19
LT2857404T (lt) 2017-11-10
KR20150014942A (ko) 2015-02-09
ES2648228T3 (es) 2017-12-29
SI2857404T1 (sl) 2017-11-30
BR112014029851A2 (pt) 2017-06-27
ZA201408843B (en) 2016-01-27
RU2635917C2 (ru) 2017-11-17
RU2014153627A (ru) 2016-08-10
KR101781255B1 (ko) 2017-09-22
AU2013272701B2 (en) 2017-12-21
WO2013183578A1 (ja) 2013-12-12
MX2014014803A (es) 2015-02-12
SG11201408052WA (en) 2015-01-29
BR112014029851B1 (pt) 2023-01-03
PH12014502721A1 (en) 2015-02-02
SMT201700539T1 (it) 2018-01-11
EP2857404A4 (en) 2016-01-20
PL2857404T3 (pl) 2018-04-30
JP5814467B2 (ja) 2015-11-17
US9187489B2 (en) 2015-11-17
IL236075A0 (en) 2015-02-01
CY1119607T1 (el) 2018-04-04
PT2857404T (pt) 2017-11-23
MX357021B (es) 2018-06-25
CA2874819A1 (en) 2013-12-12
CN104520300A (zh) 2015-04-15
HRP20171724T1 (hr) 2018-01-12
TWI585088B (zh) 2017-06-01
NO2857404T3 (Direct) 2018-01-20

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