DK2814514T3 - Histidyl tRNA synthetases for the treatment of autoimmune and inflammatory diseases - Google Patents

Histidyl tRNA synthetases for the treatment of autoimmune and inflammatory diseases Download PDF

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Publication number
DK2814514T3
DK2814514T3 DK13749967.9T DK13749967T DK2814514T3 DK 2814514 T3 DK2814514 T3 DK 2814514T3 DK 13749967 T DK13749967 T DK 13749967T DK 2814514 T3 DK2814514 T3 DK 2814514T3
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hrs
present disclosure
hrs polypeptide
polypeptide
disease
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DK13749967.9T
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Danish (da)
English (en)
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Ching Fun Lau
Wing-Sze Lo
Kyle P Chiang
Elisabeth Gardiner
Jeffrey Greve
Melissa Ashlock
John D Mendlein
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Atyr Pharma Inc
Pangu Biopharma Ltd
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Publication of DK2814514T3 publication Critical patent/DK2814514T3/en

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    • C12N9/00Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/93Ligases (6)
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61K38/43Enzymes; Proenzymes; Derivatives thereof
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    • C12Y601/00Ligases forming carbon-oxygen bonds (6.1)
    • C12Y601/01Ligases forming aminoacyl-tRNA and related compounds (6.1.1)
    • C12Y601/01021Histidine-tRNA ligase (6.1.1.21)
    • GPHYSICS
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    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
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    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61K48/005Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy characterised by an aspect of the 'active' part of the composition delivered, i.e. the nucleic acid delivered
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    • C12Q2600/00Oligonucleotides characterized by their use
    • C12Q2600/158Expression markers
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    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/90Enzymes; Proenzymes
    • G01N2333/9015Ligases (6)
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00Detection or diagnosis of diseases
    • G01N2800/52Predicting or monitoring the response to treatment, e.g. for selection of therapy based on assay results in personalised medicine; Prognosis
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02ATECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

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DK13749967.9T 2012-02-16 2013-02-15 Histidyl tRNA synthetases for the treatment of autoimmune and inflammatory diseases DK2814514T3 (en)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US201261599802P 2012-02-16 2012-02-16
US201261655358P 2012-06-04 2012-06-04
US201261725414P 2012-11-12 2012-11-12
PCT/US2013/026494 WO2013123432A2 (en) 2012-02-16 2013-02-15 Histidyl-trna synthetases for treating autoimmune and inflammatory diseases

Publications (1)

Publication Number Publication Date
DK2814514T3 true DK2814514T3 (en) 2017-12-18

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DK13749967.9T DK2814514T3 (en) 2012-02-16 2013-02-15 Histidyl tRNA synthetases for the treatment of autoimmune and inflammatory diseases

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US (3) US8835387B2 (en:Method)
EP (2) EP3311847A1 (en:Method)
JP (2) JP6170077B2 (en:Method)
KR (1) KR20140123571A (en:Method)
CN (1) CN104334196B (en:Method)
AU (2) AU2013221317B2 (en:Method)
CA (1) CA2864300A1 (en:Method)
DK (1) DK2814514T3 (en:Method)
ES (1) ES2652136T3 (en:Method)
IN (1) IN2014MN01642A (en:Method)
MX (1) MX356107B (en:Method)
NZ (1) NZ628126A (en:Method)
RU (1) RU2659423C2 (en:Method)
WO (1) WO2013123432A2 (en:Method)

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