DK2788491T3 - RIBOSOMAL PROMOTERS FROM B. SUBTILIS FOR PROTEIN PRODUCTION IN MICRO-ORGANISMS - Google Patents
RIBOSOMAL PROMOTERS FROM B. SUBTILIS FOR PROTEIN PRODUCTION IN MICRO-ORGANISMS Download PDFInfo
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- DK2788491T3 DK2788491T3 DK12806777.4T DK12806777T DK2788491T3 DK 2788491 T3 DK2788491 T3 DK 2788491T3 DK 12806777 T DK12806777 T DK 12806777T DK 2788491 T3 DK2788491 T3 DK 2788491T3
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Classifications
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/14—Hydrolases (3)
- C12N9/48—Hydrolases (3) acting on peptide bonds (3.4)
- C12N9/50—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25)
- C12N9/52—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from bacteria or Archaea
- C12N9/54—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from bacteria or Archaea bacteria being Bacillus
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/74—Vectors or expression systems specially adapted for prokaryotic hosts other than E. coli, e.g. Lactobacillus, Micromonospora
- C12N15/75—Vectors or expression systems specially adapted for prokaryotic hosts other than E. coli, e.g. Lactobacillus, Micromonospora for Bacillus
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Y—ENZYMES
- C12Y304/00—Hydrolases acting on peptide bonds, i.e. peptidases (3.4)
- C12Y304/21—Serine endopeptidases (3.4.21)
- C12Y304/21062—Subtilisin (3.4.21.62)
Landscapes
- Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Chemical & Material Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Organic Chemistry (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Biomedical Technology (AREA)
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- Biotechnology (AREA)
- Biochemistry (AREA)
- Microbiology (AREA)
- Molecular Biology (AREA)
- General Health & Medical Sciences (AREA)
- Biophysics (AREA)
- Plant Pathology (AREA)
- Physics & Mathematics (AREA)
- Medicinal Chemistry (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Enzymes And Modification Thereof (AREA)
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| US201161569202P | 2011-12-09 | 2011-12-09 | |
| US201161577491P | 2011-12-19 | 2011-12-19 | |
| PCT/US2012/068285 WO2013086219A1 (en) | 2011-12-09 | 2012-12-06 | Ribosomal promotors from b. subtilis for protein production in microorganisms |
Publications (1)
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| DK2788491T3 true DK2788491T3 (en) | 2019-04-01 |
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| EP (1) | EP2788491B1 (enExample) |
| JP (1) | JP6378089B2 (enExample) |
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| DK (1) | DK2788491T3 (enExample) |
| WO (1) | WO2013086219A1 (enExample) |
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| EP3259358B1 (en) * | 2015-02-19 | 2024-06-19 | Danisco US Inc. | Enhanced protein expression |
| WO2017075195A1 (en) | 2015-10-30 | 2017-05-04 | Danisco Us Inc | Enhanced protein expression and methods thereof |
| MX391716B (es) * | 2015-12-14 | 2025-03-21 | Basf Se | Promotor de catalasa modificado bidireccional de bacilo. |
| DK3380496T3 (da) | 2015-12-23 | 2020-08-24 | Danisco Us Inc | Forbedret proteinproduktion og fremgangsmåder hertil |
| EP3419991B1 (en) * | 2016-03-04 | 2022-10-26 | Danisco US Inc. | Engineered ribosomal promoters for protein production in microorganisms |
| CA3027745A1 (en) | 2016-06-17 | 2017-12-21 | Danisco Us Inc. | Protease variants and uses thereof |
| WO2018118917A1 (en) | 2016-12-21 | 2018-06-28 | Danisco Us Inc. | Protease variants and uses thereof |
| CN110312794B (zh) | 2016-12-21 | 2024-04-12 | 丹尼斯科美国公司 | 吉氏芽孢杆菌进化枝丝氨酸蛋白酶 |
| RU2771261C2 (ru) | 2016-12-21 | 2022-04-29 | ДюПон НЬЮТРИШН БАЙОСАЙЕНСИЗ АпС | Способы применения термостабильных сериновых протеаз |
| US20190367932A1 (en) | 2017-01-23 | 2019-12-05 | Danisco Us Inc. | Methods and compositions for obtaining natural comptence in bacillus host cells |
| US11866713B2 (en) | 2017-02-24 | 2024-01-09 | Danisco Us Inc. | Compositions and methods for increased protein production in bacillus licheniformis |
| CN110621777A (zh) | 2017-03-15 | 2019-12-27 | 杜邦营养生物科学有限公司 | 胰蛋白酶样丝氨酸蛋白酶及其用途 |
| BR112019018983A2 (pt) | 2017-03-15 | 2020-04-14 | Dupont Nutrition Biosci Aps | métodos de uso de uma serina protease archaeal |
| WO2018169750A1 (en) | 2017-03-15 | 2018-09-20 | Danisco Us Inc | Trypsin-like serine proteases and uses thereof |
| KR102533803B1 (ko) | 2017-04-07 | 2023-05-18 | 듀폰 뉴트리션 바이오사이언시즈 에이피에스 | p-니트로벤질에스터라제 부활성의 부재 하에 β-갈락토시다제 및 락타제를 생산하는 바실러스 숙주 세포 |
| KR20200047668A (ko) | 2017-09-13 | 2020-05-07 | 다니스코 유에스 인크. | 바실러스에서 증가된 단백질 생산을 위한 변형된 5'-비번역 영역(utr) 서열 |
| WO2019108599A1 (en) | 2017-11-29 | 2019-06-06 | Danisco Us Inc | Subtilisin variants having improved stability |
| DK3735478T5 (da) | 2018-01-03 | 2024-08-26 | Danisco Us Inc | Mutante og genmodificerede bacillus-celler og fremgangsmåder dertil til forøget proteinproduktion |
| CN110004166A (zh) * | 2018-01-05 | 2019-07-12 | 中国科学院天津工业生物技术研究所 | 高效表达分泌β-甘露聚糖酶的重组枯草芽孢杆菌菌株及其获得方法 |
| CN108441489B (zh) * | 2018-04-09 | 2023-04-14 | 潍坊康地恩生物科技有限公司 | 一种蛋白生产方法及高产碱性蛋白酶的枯草芽孢杆菌 |
| EP3810767A1 (en) | 2018-06-19 | 2021-04-28 | Danisco US Inc. | Subtilisin variants |
| EP3799601A1 (en) | 2018-06-19 | 2021-04-07 | Danisco US Inc. | Subtilisin variants |
| US20210277374A1 (en) | 2018-07-06 | 2021-09-09 | Dupont Nutrition Biosciences Aps | Xylanase-containing feed additives for cereal-based animal feed |
| KR20210096629A (ko) | 2018-11-28 | 2021-08-05 | 다니스코 유에스 인크. | 바실러스 세포에서의 향상된 단백질 생산을 위한 신규 프로모터 서열 및 이의 방법 |
| MX2021012158A (es) | 2019-04-05 | 2022-01-06 | Danisco Us Inc | Métodos para la integración de una secuencia de adn donante en el genoma de bacillus usando constructos de adn recombinante lineal y composiciones de los mismos. |
| MX2021012157A (es) | 2019-04-05 | 2022-01-06 | Danisco Us Inc | Métodos para la integración de polinucleótidos en el genoma de bacillus usando constructos de adn recombinante circular dual y composiciones de los mismos. |
| CN111944808B (zh) * | 2019-05-16 | 2025-04-29 | 武汉合生科技有限公司 | 核糖体rna启动子在强启动表达非rna基因中的用途 |
| CA3155372A1 (en) | 2019-10-28 | 2021-05-06 | Sharief Barends | Microbial host cells for the production of heterologous cyanuric acid hydrolases and biuret hydrolases |
| JP2023502967A (ja) | 2019-11-19 | 2023-01-26 | ダニスコ・ユーエス・インク | バチルス（Ｂａｃｉｌｌｕｓ）のゲノムを改変するための、選択マーカーを使用しない方法及びその組成物 |
| IL322673A (en) * | 2019-12-31 | 2025-10-01 | Air Protein Inc | High-protein food compositions |
| WO2021146411A1 (en) | 2020-01-15 | 2021-07-22 | Danisco Us Inc | Compositions and methods for enhanced protein production in bacillus licheniformis |
| AU2023272468A1 (en) | 2022-05-14 | 2024-11-14 | Novonesis Plant Biosolutions A/S | Compositions and methods for preventing, treating, supressing and/or eliminating phytopathogenic infestations and infections |
| CN120129752A (zh) * | 2022-09-02 | 2025-06-10 | 丹尼斯科美国公司 | 增强革兰氏阳性细胞中的蛋白质生产的新型启动子和5′-非翻译区突变 |
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| WO2010123754A1 (en) | 2009-04-24 | 2010-10-28 | Danisco Us Inc. | Proteases with modified pro regions |
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| EP2459714A1 (en) | 2009-07-31 | 2012-06-06 | Danisco US Inc. | Proteases with modified pre-pro regions |
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- 2012-12-06 CN CN201280059922.9A patent/CN104053780A/zh active Pending
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- 2012-12-06 WO PCT/US2012/068285 patent/WO2013086219A1/en not_active Ceased
- 2012-12-06 EP EP12806777.4A patent/EP2788491B1/en active Active
Also Published As
| Publication number | Publication date |
|---|---|
| JP2015500032A (ja) | 2015-01-05 |
| CN104053780A (zh) | 2014-09-17 |
| EP2788491A1 (en) | 2014-10-15 |
| WO2013086219A1 (en) | 2013-06-13 |
| US20140329309A1 (en) | 2014-11-06 |
| EP2788491B1 (en) | 2019-01-23 |
| JP6378089B2 (ja) | 2018-08-22 |
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