DK2766392T3 - Fremgangsmåde til oprensning af antistoffer - Google Patents
Fremgangsmåde til oprensning af antistoffer Download PDFInfo
- Publication number
- DK2766392T3 DK2766392T3 DK12783743.3T DK12783743T DK2766392T3 DK 2766392 T3 DK2766392 T3 DK 2766392T3 DK 12783743 T DK12783743 T DK 12783743T DK 2766392 T3 DK2766392 T3 DK 2766392T3
- Authority
- DK
- Denmark
- Prior art keywords
- procedure
- antibodies
- cleaning
- cleaning antibodies
- Prior art date
Links
- 238000004140 cleaning Methods 0.000 title 1
- 238000000034 method Methods 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/46—Hybrid immunoglobulins
- C07K16/468—Immunoglobulins having two or more different antigen binding sites, e.g. multifunctional antibodies
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/22—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against growth factors ; against growth regulators
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
- C07K1/14—Extraction; Separation; Purification
- C07K1/16—Extraction; Separation; Purification by chromatography
- C07K1/18—Ion-exchange chromatography
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
- C07K2317/24—Immunoglobulins specific features characterized by taxonomic origin containing regions, domains or residues from different species, e.g. chimeric, humanized or veneered
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/30—Immunoglobulins specific features characterized by aspects of specificity or valency
- C07K2317/31—Immunoglobulins specific features characterized by aspects of specificity or valency multispecific
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
- C07K2317/52—Constant or Fc region; Isotype
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
- C07K2317/52—Constant or Fc region; Isotype
- C07K2317/522—CH1 domain
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
- C07K2317/52—Constant or Fc region; Isotype
- C07K2317/524—CH2 domain
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
- C07K2317/52—Constant or Fc region; Isotype
- C07K2317/526—CH3 domain
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
- C07K2317/52—Constant or Fc region; Isotype
- C07K2317/53—Hinge
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
- C07K2317/72—Increased effector function due to an Fc-modification
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/90—Immunoglobulins specific features characterized by (pharmaco)kinetic aspects or by stability of the immunoglobulin
- C07K2317/94—Stability, e.g. half-life, pH, temperature or enzyme-resistance
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Immunology (AREA)
- Medicinal Chemistry (AREA)
- Biophysics (AREA)
- General Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Biochemistry (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Life Sciences & Earth Sciences (AREA)
- Peptides Or Proteins (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201161545498P | 2011-10-10 | 2011-10-10 | |
| US201261593846P | 2012-02-01 | 2012-02-01 | |
| US201261598686P | 2012-02-14 | 2012-02-14 | |
| US201213568028A | 2012-08-06 | 2012-08-06 | |
| PCT/US2012/059582 WO2013055809A1 (en) | 2011-10-10 | 2012-10-10 | A method for purifying antibodies |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DK2766392T3 true DK2766392T3 (da) | 2019-10-07 |
Family
ID=47146686
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK12783743.3T DK2766392T3 (da) | 2011-10-10 | 2012-10-10 | Fremgangsmåde til oprensning af antistoffer |
Country Status (6)
| Country | Link |
|---|---|
| EP (2) | EP2766392B1 (enExample) |
| JP (3) | JP6310394B2 (enExample) |
| AU (4) | AU2012323287B2 (enExample) |
| CA (2) | CA2851534C (enExample) |
| DK (1) | DK2766392T3 (enExample) |
| WO (1) | WO2013055809A1 (enExample) |
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| US12466897B2 (en) | 2011-10-10 | 2025-11-11 | Xencor, Inc. | Heterodimeric human IgG1 polypeptides with isoelectric point modifications |
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| US10131710B2 (en) | 2013-01-14 | 2018-11-20 | Xencor, Inc. | Optimized antibody variable regions |
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| IL263542B2 (en) | 2016-06-14 | 2024-10-01 | Xencor Inc | Bispecific antibodies inhibit immunological checkpoint |
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-
2012
- 2012-10-10 CA CA2851534A patent/CA2851534C/en active Active
- 2012-10-10 JP JP2014535821A patent/JP6310394B2/ja not_active Expired - Fee Related
- 2012-10-10 EP EP12783743.3A patent/EP2766392B1/en active Active
- 2012-10-10 DK DK12783743.3T patent/DK2766392T3/da active
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- 2012-10-10 WO PCT/US2012/059582 patent/WO2013055809A1/en not_active Ceased
- 2012-10-10 EP EP19186573.2A patent/EP3611187A1/en not_active Ceased
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2018
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2020
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| JP2015500002A (ja) | 2015-01-05 |
| AU2023270275A1 (en) | 2024-02-08 |
| CA2851534A1 (en) | 2013-04-18 |
| AU2018202978B2 (en) | 2020-04-23 |
| JP2018088938A (ja) | 2018-06-14 |
| JP6310394B2 (ja) | 2018-04-11 |
| CA2851534C (en) | 2023-02-14 |
| JP6667562B2 (ja) | 2020-03-18 |
| AU2012323287B2 (en) | 2018-02-01 |
| EP3611187A1 (en) | 2020-02-19 |
| WO2013055809A1 (en) | 2013-04-18 |
| AU2012323287A1 (en) | 2014-05-29 |
| JP7022162B2 (ja) | 2022-02-17 |
| EP2766392A1 (en) | 2014-08-20 |
| JP2020099337A (ja) | 2020-07-02 |
| EP2766392B1 (en) | 2019-07-17 |
| CA3182462A1 (en) | 2013-04-18 |
| AU2020207803A1 (en) | 2020-08-06 |
| AU2018202978A1 (en) | 2018-05-17 |
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