DK2722387T3 - Definitiv endoderm - Google Patents
Definitiv endoderm Download PDFInfo
- Publication number
- DK2722387T3 DK2722387T3 DK13186231.0T DK13186231T DK2722387T3 DK 2722387 T3 DK2722387 T3 DK 2722387T3 DK 13186231 T DK13186231 T DK 13186231T DK 2722387 T3 DK2722387 T3 DK 2722387T3
- Authority
- DK
- Denmark
- Prior art keywords
- endoderm
- definitely
- definitely endoderm
- Prior art date
Links
- 210000001900 endoderm Anatomy 0.000 title 1
Classifications
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/06—Animal cells or tissues; Human cells or tissues
- C12N5/0602—Vertebrate cells
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/06—Animal cells or tissues; Human cells or tissues
- C12N5/0602—Vertebrate cells
- C12N5/0603—Embryonic cells ; Embryoid bodies
- C12N5/0606—Pluripotent embryonic cells, e.g. embryonic stem cells [ES]
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- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/06—Animal cells or tissues; Human cells or tissues
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/06—Animal cells or tissues; Human cells or tissues
- C12N5/0602—Vertebrate cells
- C12N5/0603—Embryonic cells ; Embryoid bodies
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/06—Animal cells or tissues; Human cells or tissues
- C12N5/0602—Vertebrate cells
- C12N5/0679—Cells of the gastro-intestinal tract
- C12N5/068—Stem cells; Progenitors
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2501/00—Active agents used in cell culture processes, e.g. differentation
- C12N2501/10—Growth factors
- C12N2501/15—Transforming growth factor beta (TGF-β)
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2501/00—Active agents used in cell culture processes, e.g. differentation
- C12N2501/10—Growth factors
- C12N2501/155—Bone morphogenic proteins [BMP]; Osteogenins; Osteogenic factor; Bone inducing factor
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2501/00—Active agents used in cell culture processes, e.g. differentation
- C12N2501/10—Growth factors
- C12N2501/16—Activin; Inhibin; Mullerian inhibiting substance
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2501/00—Active agents used in cell culture processes, e.g. differentation
- C12N2501/40—Regulators of development
- C12N2501/415—Wnt; Frizzeled
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2502/00—Coculture with; Conditioned medium produced by
- C12N2502/13—Coculture with; Conditioned medium produced by connective tissue cells; generic mesenchyme cells, e.g. so-called "embryonic fibroblasts"
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2506/00—Differentiation of animal cells from one lineage to another; Differentiation of pluripotent cells
- C12N2506/02—Differentiation of animal cells from one lineage to another; Differentiation of pluripotent cells from embryonic cells
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Biomedical Technology (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Wood Science & Technology (AREA)
- Zoology (AREA)
- Biotechnology (AREA)
- Genetics & Genomics (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Microbiology (AREA)
- Biochemistry (AREA)
- General Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Developmental Biology & Embryology (AREA)
- Cell Biology (AREA)
- Reproductive Health (AREA)
- Gynecology & Obstetrics (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Gastroenterology & Hepatology (AREA)
- Analytical Chemistry (AREA)
- Biophysics (AREA)
- Physics & Mathematics (AREA)
- Immunology (AREA)
- Molecular Biology (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Peptides Or Proteins (AREA)
Applications Claiming Priority (4)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US53200403P | 2003-12-23 | 2003-12-23 | |
| US58656604P | 2004-07-09 | 2004-07-09 | |
| US58794204P | 2004-07-14 | 2004-07-14 | |
| EP04815710.1A EP1709159B1 (en) | 2003-12-23 | 2004-12-23 | Definitive endoderm |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DK2722387T3 true DK2722387T3 (da) | 2020-01-20 |
Family
ID=34743694
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK13186231.0T DK2722387T3 (da) | 2003-12-23 | 2004-12-23 | Definitiv endoderm |
| DK04815710.1T DK1709159T3 (da) | 2003-12-23 | 2004-12-23 | Definitiv endoderm |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK04815710.1T DK1709159T3 (da) | 2003-12-23 | 2004-12-23 | Definitiv endoderm |
Country Status (15)
| Country | Link |
|---|---|
| US (8) | US7704738B2 (enExample) |
| EP (2) | EP2722387B1 (enExample) |
| JP (7) | JP4819697B2 (enExample) |
| KR (1) | KR101221302B1 (enExample) |
| CN (2) | CN103898045B (enExample) |
| AU (2) | AU2004309421B2 (enExample) |
| CA (2) | CA2807342C (enExample) |
| DK (2) | DK2722387T3 (enExample) |
| EA (1) | EA200601231A1 (enExample) |
| HK (3) | HK1197082A1 (enExample) |
| IL (1) | IL176336A (enExample) |
| MX (2) | MX2009009225A (enExample) |
| NZ (1) | NZ547920A (enExample) |
| SG (1) | SG149061A1 (enExample) |
| WO (1) | WO2005063971A2 (enExample) |
Families Citing this family (150)
| Publication number | Priority date | Publication date | Assignee | Title |
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| US7432104B2 (en) * | 2001-08-06 | 2008-10-07 | Bresgen Inc. | Methods for the culture of human embryonic stem cells on human feeder cells |
| KR101008868B1 (ko) * | 2001-12-07 | 2011-01-17 | 제론 코포레이션 | 인간 배아 줄기세포 유래의 섬세포 |
| US20060003446A1 (en) | 2002-05-17 | 2006-01-05 | Gordon Keller | Mesoderm and definitive endoderm cell populations |
| EP2361966A1 (en) | 2002-05-17 | 2011-08-31 | Mount Sinai School of Medicine of New York University | Mesoderm and definitive endoderm cell populations |
| US7541185B2 (en) | 2003-12-23 | 2009-06-02 | Cythera, Inc. | Methods for identifying factors for differentiating definitive endoderm |
| US8647873B2 (en) | 2004-04-27 | 2014-02-11 | Viacyte, Inc. | PDX1 expressing endoderm |
| US7985585B2 (en) | 2004-07-09 | 2011-07-26 | Viacyte, Inc. | Preprimitive streak and mesendoderm cells |
| CN103898045B (zh) | 2003-12-23 | 2019-02-01 | 维亚希特公司 | 定形内胚层 |
| WO2007059007A2 (en) * | 2005-11-14 | 2007-05-24 | Cythera, Inc. | Markers of definitive endoderm |
| US20050266554A1 (en) * | 2004-04-27 | 2005-12-01 | D Amour Kevin A | PDX1 expressing endoderm |
| US7625753B2 (en) | 2003-12-23 | 2009-12-01 | Cythera, Inc. | Expansion of definitive endoderm cells |
| EP2377922B1 (en) * | 2004-04-27 | 2020-04-08 | Viacyte, Inc. | PDX1 expressing endoderm |
| US20090010900A1 (en) * | 2004-07-07 | 2009-01-08 | The University Of North Carlolina At Chapel Hill | Embryonic Stem Cell Derivatives, and Methods of Making and Using the Same |
| CA2573354C (en) * | 2004-07-09 | 2015-02-24 | Cythera, Inc. | Preprimitive streak and mesendoderm cells |
| US8187878B2 (en) * | 2004-08-13 | 2012-05-29 | University Of Georgia Research Foundation, Inc. | Methods for increasing definitive endoderm differentiation of pluripotent human embryonic stem cells with PI-3 kinase inhibitors |
| WO2006040763A2 (en) * | 2004-10-12 | 2006-04-20 | Technion Research & Development Foundation Ltd. | Isolated primate embryonic cells and methods of generating and using same |
| US8017395B2 (en) | 2004-12-17 | 2011-09-13 | Lifescan, Inc. | Seeding cells on porous supports |
| DK1838843T3 (da) * | 2004-12-23 | 2019-08-26 | Viacyte Inc | Ekspansion af definitive endodermceller |
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- 2004-12-23 EP EP13186231.0A patent/EP2722387B1/en not_active Expired - Lifetime
- 2004-12-23 EP EP04815710.1A patent/EP1709159B1/en not_active Expired - Lifetime
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2006
- 2006-06-15 IL IL176336A patent/IL176336A/en active IP Right Grant
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2009
- 2009-03-30 US US12/414,482 patent/US8623645B2/en active Active
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2010
- 2010-02-22 US US12/710,300 patent/US20100151568A1/en not_active Abandoned
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2011
- 2011-04-06 AU AU2011201552A patent/AU2011201552B2/en not_active Expired
- 2011-08-01 JP JP2011168363A patent/JP5669688B2/ja not_active Expired - Lifetime
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2013
- 2013-11-05 US US14/072,642 patent/US20140134727A1/en not_active Abandoned
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2014
- 2014-09-12 JP JP2014186172A patent/JP6356021B2/ja not_active Expired - Lifetime
- 2014-10-21 HK HK14110480.0A patent/HK1197082A1/en unknown
- 2014-12-31 HK HK14113097.9A patent/HK1199740A1/xx unknown
- 2014-12-31 HK HK14113099.7A patent/HK1199741A1/xx unknown
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2015
- 2015-06-01 JP JP2015111659A patent/JP2015163081A/ja active Pending
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2016
- 2016-11-30 JP JP2016232292A patent/JP6574158B2/ja not_active Expired - Lifetime
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2017
- 2017-02-13 US US15/431,634 patent/US10421942B2/en not_active Expired - Lifetime
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2018
- 2018-07-09 JP JP2018130280A patent/JP2018171071A/ja active Pending
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2019
- 2019-08-13 US US16/539,966 patent/US20190376028A1/en not_active Abandoned
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2020
- 2020-02-27 JP JP2020032178A patent/JP7045407B2/ja not_active Expired - Lifetime
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2021
- 2021-11-05 US US17/519,823 patent/US20220056405A1/en not_active Abandoned
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