DK268779A - Fremgangsmaade til fremstilling af phenethanolaminer - Google Patents

Fremgangsmaade til fremstilling af phenethanolaminer

Info

Publication number
DK268779A
DK268779A DK268779A DK268779A DK268779A DK 268779 A DK268779 A DK 268779A DK 268779 A DK268779 A DK 268779A DK 268779 A DK268779 A DK 268779A DK 268779 A DK268779 A DK 268779A
Authority
DK
Denmark
Prior art keywords
phenethanolamines
procedure
preparation
Prior art date
Application number
DK268779A
Other languages
Danish (da)
English (en)
Inventor
J Mills
K K Schmiegel
W S Shaw
Original Assignee
Lilly Co Eli
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Lilly Co Eli filed Critical Lilly Co Eli
Publication of DK268779A publication Critical patent/DK268779A/da

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C253/00Preparation of carboxylic acid nitriles
    • C07C253/06Preparation of carboxylic acid nitriles from N-formylated amino compounds
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C255/00Carboxylic acid nitriles
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/04Anorexiants; Antiobesity agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/06Antihyperlipidemics
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C229/00Compounds containing amino and carboxyl groups bound to the same carbon skeleton
    • C07C229/38Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino groups bound to acyclic carbon atoms and carboxyl groups bound to carbon atoms of six-membered aromatic rings of the same carbon skeleton
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C243/00Compounds containing chains of nitrogen atoms singly-bound to each other, e.g. hydrazines, triazanes
    • C07C243/24Hydrazines having nitrogen atoms of hydrazine groups acylated by carboxylic acids
    • C07C243/38Hydrazines having nitrogen atoms of hydrazine groups acylated by carboxylic acids with acylating carboxyl groups bound to carbon atoms of six-membered aromatic rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C29/00Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom not belonging to a six-membered aromatic ring
    • C07C29/132Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom not belonging to a six-membered aromatic ring by reduction of an oxygen containing functional group
    • C07C29/136Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom not belonging to a six-membered aromatic ring by reduction of an oxygen containing functional group of >C=O containing groups, e.g. —COOH
    • C07C29/147Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom not belonging to a six-membered aromatic ring by reduction of an oxygen containing functional group of >C=O containing groups, e.g. —COOH of carboxylic acids or derivatives thereof
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C51/00Preparation of carboxylic acids or their salts, halides or anhydrides
    • C07C51/42Separation; Purification; Stabilisation; Use of additives
    • C07C51/487Separation; Purification; Stabilisation; Use of additives by treatment giving rise to chemical modification
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D303/00Compounds containing three-membered rings having one oxygen atom as the only ring hetero atom
    • C07D303/02Compounds containing oxirane rings
    • C07D303/04Compounds containing oxirane rings containing only hydrogen and carbon atoms in addition to the ring oxygen atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Health & Medical Sciences (AREA)
  • Hematology (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Diabetes (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Obesity (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Child & Adolescent Psychology (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Fodder In General (AREA)
  • Dairy Products (AREA)
DK268779A 1978-07-03 1979-06-26 Fremgangsmaade til fremstilling af phenethanolaminer DK268779A (da)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US92167078A 1978-07-03 1978-07-03

Publications (1)

Publication Number Publication Date
DK268779A true DK268779A (da) 1980-01-04

Family

ID=25445792

Family Applications (2)

Application Number Title Priority Date Filing Date
DK268779A DK268779A (da) 1978-07-03 1979-06-26 Fremgangsmaade til fremstilling af phenethanolaminer
DK268679A DK160936C (da) 1978-07-03 1979-06-26 Analogifremgangsmaade til fremstilling af optisk aktive phenethanolaminer

Family Applications After (1)

Application Number Title Priority Date Filing Date
DK268679A DK160936C (da) 1978-07-03 1979-06-26 Analogifremgangsmaade til fremstilling af optisk aktive phenethanolaminer

Country Status (31)

Country Link
EP (3) EP0048037A1 (de)
JP (2) JPS559096A (de)
KR (1) KR880002310B1 (de)
AR (4) AR225744A1 (de)
AT (2) AT372937B (de)
AU (2) AU523720B2 (de)
BE (2) BE877393A (de)
BG (4) BG31645A3 (de)
CA (2) CA1145767A (de)
CH (2) CH643529A5 (de)
CS (4) CS208664B2 (de)
DD (2) DD144762A5 (de)
DE (2) DE2964091D1 (de)
DK (2) DK268779A (de)
EG (1) EG14238A (de)
ES (4) ES482155A1 (de)
FI (2) FI792081A (de)
FR (3) FR2430411A1 (de)
GB (3) GB2028799B (de)
GR (2) GR72940B (de)
HU (2) HU179172B (de)
IE (2) IE48586B1 (de)
IL (2) IL57671A (de)
LU (2) LU81458A1 (de)
NZ (2) NZ190861A (de)
PH (2) PH15275A (de)
PL (4) PL121297B1 (de)
PT (2) PT69843A (de)
RO (4) RO83051B (de)
SU (4) SU965350A3 (de)
ZA (2) ZA793297B (de)

Families Citing this family (36)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2965655D1 (en) * 1978-06-28 1983-07-21 Beecham Group Plc Secondary amines, their preparation, pharmaceutical compositions containing them and their use
EP0028105B1 (de) * 1979-10-25 1983-01-19 Beecham Group Plc Sekundäre Amine, ihre Herstellung und Verwendung in pharmazeutischen Zusammensetzungen
ATE14222T1 (de) * 1979-11-15 1985-07-15 Beecham Group Plc Sekundaere aethanolamine, ihre herstellung und ihre verwendung in pharmazeutischen zusammensetzungen.
DE3161165D1 (en) * 1980-05-08 1983-11-17 Beecham Group Plc Arylethanolamine derivatives, their preparation and use in pharmaceutical compositions
EP0066351B1 (de) * 1981-03-06 1985-06-26 Beecham Group Plc Aryläthanolamin-Derivate, ihre Herstellung und Verwendung in pharmazeutischen Zusammensetzungen
EP0061907B1 (de) * 1981-03-31 1984-08-01 Beecham Group Plc Sekundäre Amine, solche enthaltende pharmazeutische Zusammensetzungen und ihre Verwendung sowie ihre Herstellung
EP0070133B1 (de) * 1981-07-11 1986-05-14 Beecham Group Plc Sekundäre Phenylethanolamine, Verfahren zu ihrer Herstellung und ihre pharmazeutische Verwendung
EP0089154A3 (de) * 1982-03-12 1984-08-08 Beecham Group Plc Ethanolamin-Derivate, ihre Herstellung und Verwendung in pharmazeutischen Zusammensetzungen
CA1219865A (en) * 1982-05-14 1987-03-31 Leo Alig Aziridine phenethanolamine derivatives
CA1258454A (en) * 1982-08-10 1989-08-15 Leo Alig Phenethanolamines
JPS5980640A (ja) * 1982-09-27 1984-05-10 イーライ・リリー・アンド・カンパニー 2−ヒドロキシ−2−フエニルエチルアミン類の製造方法
EP0117647B1 (de) * 1983-01-31 1988-08-17 Eli Lilly And Company Phenethanolamine
CA1262729A (en) * 1983-10-19 1989-11-07 Leo Alig Phenoxypropanolamines
US5166218A (en) * 1983-10-19 1992-11-24 Hoffmann-La Roche Inc. Phenoxypropanolamines and pharmaceutical compositions thereof
US4602044A (en) * 1983-12-19 1986-07-22 Eli Lilly And Company β-phenethanolamine antiobesity agents
HU191313B (en) * 1984-01-12 1987-02-27 Eli Lilly And Co,Us Process for preparing compounds with inotropic activity
GB8505284D0 (en) * 1985-03-01 1985-04-03 Beecham Group Plc Growth promoters
PT82120B (en) * 1985-03-01 1988-06-16 Beecham Group Plc Process for preparing veterinary formulations containing ethanolamine derivatives
IT1204416B (it) * 1986-06-27 1989-03-01 Midy Spa Medicamenti a base di analoghi di feniletanolammine per il trattamento di disturbi gastro-intestinali ed uterini
JP2837408B2 (ja) * 1987-05-30 1998-12-16 鐘紡株式会社 アクリル系繊維の処理方法
US5135955A (en) * 1988-04-25 1992-08-04 Eli Lilly And Company Propanamine derivatives
FI892341A (fi) * 1988-06-10 1989-12-11 Hoffmann La Roche Propanolaminderivat.
CA2023954C (en) * 1989-10-17 1999-05-04 Hiroyuki Nohira Process for the optical resolution of 2-(3-benzoyl) phenylpropionic acid
US6011068A (en) * 1991-08-23 2000-01-04 Nps Pharmaceuticals, Inc. Calcium receptor-active molecules
US5688938A (en) * 1991-08-23 1997-11-18 The Brigham & Women's Hospital, Inc. Calcium receptor-active molecules
JP2728564B2 (ja) * 1991-08-23 1998-03-18 エヌピーエス・ファーマシウティカルズ・インコーポレイテッド カルシウム受容体活性化分子
US6001884A (en) * 1991-08-23 1999-12-14 Nps Pharmaceuticals, Inc. Calcium receptor-active molecules
US5763569A (en) * 1991-08-23 1998-06-09 The Brigham And Women's Hospital, Inc Calcium receptor-active molecules
US6031003A (en) * 1991-08-23 2000-02-29 Nps Pharmaceuticals, Inc. Calcium receptor-active molecules
US6313146B1 (en) 1991-08-23 2001-11-06 Nps Pharmaceuticals, Inc. Calcium receptor-active molecules
US5858684A (en) * 1991-08-23 1999-01-12 The Brigham And Women's Hospital, Inc. Method of screening calcium receptor-active molecules
US5321036A (en) * 1993-02-10 1994-06-14 Bristol-Myers Squibb Company Thiazole and oxazole-based β3 adrenergic receptor agonists
US5962314A (en) * 1993-02-23 1999-10-05 Nps Pharmaceuticals, Inc. Calcium receptor-active molecules
ATE287390T1 (de) 1994-10-21 2005-02-15 Nps Pharma Inc Kalzium-rezeptor aktive verbindungen
ATE430123T1 (de) 1996-05-01 2009-05-15 Nps Pharma Inc Inorganische am ionen-rezeptor aktive verbindungen
US7321065B2 (en) * 2003-04-18 2008-01-22 The Regents Of The University Of California Thyronamine derivatives and analogs and methods of use thereof

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NL56308C (de) * 1941-03-15
GB1200886A (en) * 1966-09-23 1970-08-05 Allen & Hanburys Ltd Phenylaminoethanol derivatives
GB1301134A (en) 1970-07-18 1972-12-29 Pfizer Ltd SUBSTITUTED 1-PHENYL-2-ALLYLAMINO-ALKANOLS, 1-PHENYL-2-ALLYLAMINO-ALKANES AND alpha-AMINOALKYLPHENYL KETONES
BE788850A (fr) * 1972-09-15 1973-03-15 Hoffmann La Roche Derives d'acide benzoique
US4000192A (en) * 1973-05-07 1976-12-28 Allen & Hanburys Limited Pharmacologically active compounds
IE39247B1 (en) * 1973-05-07 1978-08-30 Allen & Hanburys Ltd Substituted benzamides
NZ190854A (en) * 1978-06-28 1984-10-19 Beecham Group Ltd 2-hydroxy-2-phenyl ethylamine derivatives;pharmaceutical compositions
DK269079A (da) * 1978-07-03 1980-02-01 Lilly Co Eli Fremgangsmaade til fremstilling af phenethanolaminer

Also Published As

Publication number Publication date
EP0007204B1 (de) 1982-11-24
GB2028802A (en) 1980-03-12
ES482156A1 (es) 1980-08-16
FR2430411B1 (de) 1983-08-19
PL117551B1 (en) 1981-08-31
ZA793297B (en) 1981-02-25
IE48586B1 (en) 1985-03-20
RO77732A (ro) 1981-11-24
CS209815B2 (en) 1981-12-31
PL117997B1 (en) 1981-09-30
SU957761A3 (ru) 1982-09-07
BG31646A3 (en) 1982-02-15
FR2430410A1 (fr) 1980-02-01
RO83052A (ro) 1984-02-21
GB2028802B (en) 1983-03-30
DD144761A5 (de) 1980-11-05
AU4848979A (en) 1980-01-10
BE877393A (fr) 1980-01-02
IL57672A (en) 1983-03-31
ES490215A0 (es) 1981-04-16
PL121297B1 (en) 1982-04-30
EP0006766B1 (de) 1983-01-26
GB2101582B (en) 1983-06-08
CA1142954A (en) 1983-03-15
FR2430410B1 (fr) 1986-03-21
AU523720B2 (en) 1982-08-12
PL117996B1 (en) 1981-09-30
KR830001187A (ko) 1983-04-29
EG14238A (en) 1983-12-31
PH14522A (en) 1981-08-26
HU179171B (en) 1982-08-28
NZ190861A (en) 1981-12-15
IL57671A (en) 1982-11-30
PT69843A (en) 1979-07-01
ES8104189A1 (es) 1981-04-16
DK268679A (da) 1980-01-04
IE791227L (en) 1980-01-03
FR2430411A1 (fr) 1980-02-01
IE791228L (en) 1980-01-03
ES490214A0 (es) 1981-04-16
AR225744A1 (es) 1982-04-30
DE2964091D1 (en) 1982-12-30
RO83051A (ro) 1984-02-21
AU523721B2 (en) 1982-08-12
CS208662B2 (en) 1981-09-15
JPS559096A (en) 1980-01-22
SU965350A3 (ru) 1982-10-07
BG31647A3 (en) 1982-02-15
PL216811A1 (de) 1980-08-25
ZA793296B (en) 1981-02-25
CA1145767A (en) 1983-05-03
LU81458A1 (fr) 1979-10-30
CH642618A5 (fr) 1984-04-30
BE877394A (fr) 1980-01-02
BG31375A3 (en) 1981-12-15
JPS559097A (en) 1980-01-22
GB2028799A (en) 1980-03-12
RO83051B (ro) 1984-02-28
GR72940B (de) 1984-01-16
FR2450806A1 (fr) 1980-10-03
DE2964604D1 (en) 1983-03-03
IL57671A0 (en) 1979-10-31
ATA463579A (de) 1983-04-15
CS208663B2 (en) 1981-09-15
EP0048037A1 (de) 1982-03-24
FR2450806B1 (fr) 1985-07-12
PL216814A1 (de) 1980-03-24
FI792082A (fi) 1980-01-04
GR74524B (de) 1984-06-29
SU1007554A3 (ru) 1983-03-23
PT69839A (en) 1979-07-01
LU81457A1 (fr) 1979-10-30
JPS6254095B2 (de) 1987-11-13
RO83052B (ro) 1984-02-28
FI792081A (fi) 1980-01-04
ES8104190A1 (es) 1981-04-16
PH15275A (en) 1982-11-02
EP0006766A1 (de) 1980-01-09
NZ190863A (en) 1982-05-25
CS208664B2 (en) 1981-09-15
DK160936B (da) 1991-05-06
HU179172B (en) 1982-08-28
RO77728A (ro) 1981-11-24
CH643529A5 (fr) 1984-06-15
ATA463679A (de) 1981-10-15
GB2101582A (en) 1983-01-19
IE48769B1 (en) 1985-05-15
AR227165A1 (es) 1982-09-30
AT367025B (de) 1982-05-25
DD144762A5 (de) 1980-11-05
AU4848779A (en) 1980-01-10
EP0007204A1 (de) 1980-01-23
AR229080A1 (es) 1983-06-15
IL57672A0 (en) 1979-10-31
KR880002310B1 (ko) 1988-10-22
BG31645A3 (en) 1982-02-15
SU849997A3 (ru) 1981-07-23
GB2028799B (en) 1982-09-08
AR231434A1 (es) 1984-11-30
DK160936C (da) 1991-10-21
AT372937B (de) 1983-11-25
ES482155A1 (es) 1980-08-16

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