DK2442835T3 - Blodstillende svamp - Google Patents
Blodstillende svamp Download PDFInfo
- Publication number
- DK2442835T3 DK2442835T3 DK10737484T DK10737484T DK2442835T3 DK 2442835 T3 DK2442835 T3 DK 2442835T3 DK 10737484 T DK10737484 T DK 10737484T DK 10737484 T DK10737484 T DK 10737484T DK 2442835 T3 DK2442835 T3 DK 2442835T3
- Authority
- DK
- Denmark
- Prior art keywords
- sponge
- blood
- particles
- matrix
- fluid
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L15/00—Chemical aspects of, or use of materials for, bandages, dressings or absorbent pads
- A61L15/16—Bandages, dressings or absorbent pads for physiological fluids such as urine or blood, e.g. sanitary towels, tampons
- A61L15/42—Use of materials characterised by their function or physical properties
- A61L15/425—Porous materials, e.g. foams or sponges
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L15/00—Chemical aspects of, or use of materials for, bandages, dressings or absorbent pads
- A61L15/16—Bandages, dressings or absorbent pads for physiological fluids such as urine or blood, e.g. sanitary towels, tampons
- A61L15/22—Bandages, dressings or absorbent pads for physiological fluids such as urine or blood, e.g. sanitary towels, tampons containing macromolecular materials
- A61L15/26—Macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds; Derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L15/00—Chemical aspects of, or use of materials for, bandages, dressings or absorbent pads
- A61L15/16—Bandages, dressings or absorbent pads for physiological fluids such as urine or blood, e.g. sanitary towels, tampons
- A61L15/22—Bandages, dressings or absorbent pads for physiological fluids such as urine or blood, e.g. sanitary towels, tampons containing macromolecular materials
- A61L15/32—Proteins, polypeptides; Degradation products or derivatives thereof, e.g. albumin, collagen, fibrin, gelatin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L15/00—Chemical aspects of, or use of materials for, bandages, dressings or absorbent pads
- A61L15/16—Bandages, dressings or absorbent pads for physiological fluids such as urine or blood, e.g. sanitary towels, tampons
- A61L15/22—Bandages, dressings or absorbent pads for physiological fluids such as urine or blood, e.g. sanitary towels, tampons containing macromolecular materials
- A61L15/32—Proteins, polypeptides; Degradation products or derivatives thereof, e.g. albumin, collagen, fibrin, gelatin
- A61L15/325—Collagen
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L15/00—Chemical aspects of, or use of materials for, bandages, dressings or absorbent pads
- A61L15/16—Bandages, dressings or absorbent pads for physiological fluids such as urine or blood, e.g. sanitary towels, tampons
- A61L15/42—Use of materials characterised by their function or physical properties
- A61L15/44—Medicaments
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L15/00—Chemical aspects of, or use of materials for, bandages, dressings or absorbent pads
- A61L15/16—Bandages, dressings or absorbent pads for physiological fluids such as urine or blood, e.g. sanitary towels, tampons
- A61L15/42—Use of materials characterised by their function or physical properties
- A61L15/58—Adhesives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L15/00—Chemical aspects of, or use of materials for, bandages, dressings or absorbent pads
- A61L15/16—Bandages, dressings or absorbent pads for physiological fluids such as urine or blood, e.g. sanitary towels, tampons
- A61L15/42—Use of materials characterised by their function or physical properties
- A61L15/64—Use of materials characterised by their function or physical properties specially adapted to be resorbable inside the body
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L26/00—Chemical aspects of, or use of materials for, wound dressings or bandages in liquid, gel or powder form
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
- A61L2300/40—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices characterised by a specific therapeutic activity or mode of action
- A61L2300/418—Agents promoting blood coagulation, blood-clotting agents, embolising agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L2400/00—Materials characterised by their function or physical properties
- A61L2400/04—Materials for stopping bleeding
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Materials Engineering (AREA)
- Epidemiology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Hematology (AREA)
- Dispersion Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Materials For Medical Uses (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Claims (15)
1. Blodstillende porøs svamp omfattende en matrix af et fibrøst biomateriale samt partikler af et fluidabsorberende partikelformigt materiale, idet partiklerne er fordelt eller indlejret eller indesluttet i matrixens fibrøse biomateriale, idet det partikelformige materiale er en blodstillende tværbunden polymer, og idet svampen endvidere omfatter et klæbelag, idet klæbelaget omfatter en første tværbindelig komponent og en anden tværbindelig komponent, der tværbinder sig med den første tværbindelige komponent under egnede reaktionsbetingelser, idet den første og/eller den anden tværbindelige komponent omfatter PEG eller et derivat deraf.
2. Svamp ifølge krav 1, hvori det fibrøse biomateriale omfatter kollagen.
3. Svamp ifølge krav 1, hvori det partikelformige materiale omfatte gelatine, fibrin, kollagen eller en vilkårlig blanding deraf.
4. Svamp ifølge krav 1, som endvidere omfatter thrombin eller et thrombinforstadium.
5. Svamp ifølge krav 1, hvori klæbelaget omfatter en bioresorberbar polymer.
6. Svamp ifølge krav 1, hvori klæbelaget omfatter succinimidyl- eller maleimidyl- og thiol- eller aminogrupper.
7. Svamp ifølge krav 1, hvori mindst én side af svampen er diskontinuerligt belagt med klæbelaget.
8. Svamp ifølge krav 1, som er frysetørret eller lufttørret.
9. Svamp ifølge krav 1, som omfatter et støttelag med større trækstyrke end matrixmaterialet.
10. Svamp ifølge krav 9, hvori støttelaget omfatter en bioresorberbar polymer.
11. Svamp ifølge krav 9, hvori støttelaget har en større tæthed en matrixmaterialet.
12. Fremgangsmåde til fremstilling af en blodstillende porøs svamp ifølge et hvilket som helst af kravene 1 til 11, omfattende tilvejebringelse af et fluid af et fibrøst biomateriale og suspenderede partikler af et fluidabsorberende partikelformigt materiale, hvori det partikelformige materiale er en blodstillende tværbunden polymer, og tørring af fluidet med de suspenderede partikler, hvorved der opnås en tørret blodstillende porøs svamp, som omfatter en matrix af et fibrøst biomateriale og partikler af et fluidabsorberende partikelformigt materiale, idet partiklerne er fordelt i eller indlejret i eller indesluttet i matrixens fibrøse biomateriale, og idet et klæbelag er fastgjort til den tørrede blodstillende svamp, idet klæbelaget omfatter en første tværbindelig komponent og en anden tværbindelig komponent, der tværbinder sig med den første tværbindelige komponent under egnede reaktionsbetingelser, idet den første og/eller den anden tværbindelige komponent omfatter PEG eller et derivat deraf.
13. Blodstillende porøs svamp ifølge et hvilket som helst af kravene 1 til 11, som kan opnås ved en fremgangsmåde ifølge krav 12.
14. Blodstillende porøs svamp ifølge et hvilket som helst af kravene 1 til 11 og 13 til anvendelse ved behandling af en læsion.
15. Svamp ifølge krav 14, hvor læsionen omfatter et sår, en blødning, beskadiget væv og/eller blødende væv.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US18757609P | 2009-06-16 | 2009-06-16 | |
PCT/EP2010/003623 WO2010145817A2 (en) | 2009-06-16 | 2010-06-16 | Hemostatic sponge |
Publications (1)
Publication Number | Publication Date |
---|---|
DK2442835T3 true DK2442835T3 (da) | 2015-03-16 |
Family
ID=42731904
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DK10737484T DK2442835T3 (da) | 2009-06-16 | 2010-06-16 | Blodstillende svamp |
Country Status (17)
Country | Link |
---|---|
US (3) | US9162006B2 (da) |
EP (1) | EP2442835B1 (da) |
JP (1) | JP5719355B2 (da) |
KR (1) | KR101699992B1 (da) |
CN (1) | CN102802683B (da) |
AU (1) | AU2010262058B2 (da) |
BR (1) | BRPI1015979A8 (da) |
CA (1) | CA2765117C (da) |
CO (1) | CO6430437A2 (da) |
DK (1) | DK2442835T3 (da) |
ES (1) | ES2532428T3 (da) |
HR (1) | HRP20150255T1 (da) |
IL (1) | IL216671A (da) |
MX (1) | MX2011013795A (da) |
PL (1) | PL2442835T3 (da) |
PT (1) | PT2442835E (da) |
WO (1) | WO2010145817A2 (da) |
Families Citing this family (68)
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AU2010262058B2 (en) | 2013-08-29 |
AU2010262058A1 (en) | 2011-12-22 |
JP5719355B2 (ja) | 2015-05-20 |
BRPI1015979B1 (pt) | 2018-05-22 |
EP2442835B1 (en) | 2014-12-10 |
IL216671A0 (en) | 2012-02-29 |
CO6430437A2 (es) | 2012-04-30 |
KR20120034078A (ko) | 2012-04-09 |
WO2010145817A3 (en) | 2011-02-17 |
BRPI1015979A2 (pt) | 2016-04-19 |
CN102802683A (zh) | 2012-11-28 |
US20150132362A1 (en) | 2015-05-14 |
US20190374673A1 (en) | 2019-12-12 |
PL2442835T3 (pl) | 2015-07-31 |
CA2765117A1 (en) | 2010-12-23 |
MX2011013795A (es) | 2012-04-30 |
US9162006B2 (en) | 2015-10-20 |
CA2765117C (en) | 2017-07-11 |
CN102802683B (zh) | 2015-11-25 |
JP2012529943A (ja) | 2012-11-29 |
US20100318048A1 (en) | 2010-12-16 |
HRP20150255T1 (hr) | 2015-05-08 |
BRPI1015979A8 (pt) | 2018-06-19 |
PT2442835E (pt) | 2015-03-23 |
KR101699992B1 (ko) | 2017-01-26 |
IL216671A (en) | 2015-06-30 |
WO2010145817A2 (en) | 2010-12-23 |
EP2442835A2 (en) | 2012-04-25 |
ES2532428T3 (es) | 2015-03-26 |
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