DK1833978T3 - Tripeptid- og tetrapeptidthioethere - Google Patents

Tripeptid- og tetrapeptidthioethere

Info

Publication number
DK1833978T3
DK1833978T3 DK06717426T DK06717426T DK1833978T3 DK 1833978 T3 DK1833978 T3 DK 1833978T3 DK 06717426 T DK06717426 T DK 06717426T DK 06717426 T DK06717426 T DK 06717426T DK 1833978 T3 DK1833978 T3 DK 1833978T3
Authority
DK
Denmark
Prior art keywords
tripeptide
tetrapeptide
thioethers
tetrapeptide thioethers
Prior art date
Application number
DK06717426T
Other languages
Danish (da)
English (en)
Inventor
Natalia Aurrecoechea
Andrew B Kelson
Robert W Macsata
Louise Robinson
Anthony J Sanchez
Nicholas M Santiago
Steven R Schow
Reyna J Simon
Original Assignee
Telik Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Telik Inc filed Critical Telik Inc
Application granted granted Critical
Publication of DK1833978T3 publication Critical patent/DK1833978T3/da

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K5/00Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/08Tripeptides
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K5/00Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/02Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link
    • C07K5/0215Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link containing natural amino acids, forming a peptide bond via their side chain functional group, e.g. epsilon-Lys, gamma-Glu
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/04Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/06Tripeptides
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Biophysics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Immunology (AREA)
  • Epidemiology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
DK06717426T 2005-01-06 2006-01-04 Tripeptid- og tetrapeptidthioethere DK1833978T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US64193205P 2005-01-06 2005-01-06
PCT/US2006/000219 WO2006074249A1 (en) 2005-01-06 2006-01-04 Tripeptide and tetrapeptide thioethers

Publications (1)

Publication Number Publication Date
DK1833978T3 true DK1833978T3 (da) 2009-02-09

Family

ID=36123437

Family Applications (2)

Application Number Title Priority Date Filing Date
DK06717426T DK1833978T3 (da) 2005-01-06 2006-01-04 Tripeptid- og tetrapeptidthioethere
DK06717699T DK1833842T3 (da) 2005-01-06 2006-01-05 Tripeptid- og tetrapeptidsulfoner

Family Applications After (1)

Application Number Title Priority Date Filing Date
DK06717699T DK1833842T3 (da) 2005-01-06 2006-01-05 Tripeptid- og tetrapeptidsulfoner

Country Status (24)

Country Link
US (2) US7129215B2 (enExample)
EP (2) EP1833978B1 (enExample)
JP (2) JP4903716B2 (enExample)
KR (2) KR101244609B1 (enExample)
CN (2) CN101090977B (enExample)
AR (2) AR051890A1 (enExample)
AT (2) ATE410520T1 (enExample)
AU (2) AU2006204022B2 (enExample)
BR (2) BRPI0606520A2 (enExample)
CA (2) CA2587284C (enExample)
DE (2) DE602006003064D1 (enExample)
DK (2) DK1833978T3 (enExample)
EA (2) EA200701398A1 (enExample)
ES (2) ES2314890T3 (enExample)
HR (2) HRP20090128T3 (enExample)
IL (2) IL182836A (enExample)
MX (2) MX2007008255A (enExample)
NZ (2) NZ555362A (enExample)
PL (2) PL1833978T3 (enExample)
PT (2) PT1833978E (enExample)
SI (2) SI1833978T1 (enExample)
TW (2) TWI317738B (enExample)
WO (2) WO2006074249A1 (enExample)
ZA (2) ZA200704487B (enExample)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8198247B2 (en) 2004-12-21 2012-06-12 Telik, Inc. Process for and intermediates in the preparation of canfosfamide and its salts
ATE410520T1 (de) * 2005-01-06 2008-10-15 Telik Inc Tripeptid- und tetrapeptid-thioether
US20070154963A1 (en) * 2005-12-30 2007-07-05 Danying Cai Method to determine whether a compound is a cellular GSTpi inhibitor
US20090221703A1 (en) 2006-07-09 2009-09-03 Chongxi Yu High penetration composition and uses thereof
US20090238763A1 (en) 2006-07-09 2009-09-24 Chongxi Yu High penetration compositions and uses thereof
AU2016213759B2 (en) * 2006-11-08 2018-03-29 Chongxi Yu Transdermal delivery systems of peptides and related compounds
EP2091914A4 (en) 2006-11-08 2010-12-29 Chongxi Yu TRANSDERMAL ADMINISTRATION SYSTEMS FOR PEPTIDES AND RELATED CONNECTIONS
CA2691446C (en) 2007-06-04 2021-07-06 Techfields Inc Pro-drugs of nsaias with very high skin and membranes penetration rates and their new medicinal uses
KR20200022525A (ko) 2008-12-04 2020-03-03 충시 위 고투과력을 가진 조성물 및 이의 적용
DE102008060888A1 (de) 2008-12-09 2010-06-10 Evonik Stockhausen Gmbh Verfahren zur Herstellung von Acrolein umfassend die Aufarbeitung einer Rohglycerin-Phase
BRPI1011439B8 (pt) 2009-05-08 2021-05-25 Yu Chongxi composição de alta penetração, composição farmacêutica, sistemas de aplicação terapêutico transdérmico e uso da referida composição
CA2797458A1 (en) * 2010-06-07 2011-12-15 Telik, Inc. Tablet formulation of ezatiostat
US8841476B2 (en) 2010-06-07 2014-09-23 Telik, Inc. Preparation of crystalline ezatiostat hydrochloride ansolvate form D
US20130035389A1 (en) * 2011-08-05 2013-02-07 Telik, Inc. Methods for treating myelodysplastic syndrome with ezatiostat
JP5970439B2 (ja) * 2013-09-20 2016-08-17 チョンシー ユー ペプチド及び関連化合物の経皮送達システム
CN106146616A (zh) * 2015-04-03 2016-11-23 浙江海正药业股份有限公司 环肽类化合物及其制备和用途

Family Cites Families (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5599903A (en) * 1992-04-03 1997-02-04 Terrapin Technologies, Inc. Glutathione analogs and paralog panels comprising glutathione mimics
US5556942A (en) * 1991-04-29 1996-09-17 Terrapin Technologies, Inc. Glutathione S-transferase-activated compounds
US5786336A (en) * 1991-04-29 1998-07-28 Terrapin Technologies, Inc. Target-selective protocols based on mimics
US5767086A (en) * 1992-04-03 1998-06-16 Terrapin Technologies, Inc. Bone marrow stimulation by certain glutathione analogs
US5955432A (en) * 1992-04-03 1999-09-21 Terrapin Technologies, Inc. Metabolic effects of certain glutathione analogs
CA2105492C (en) * 1993-09-03 2000-02-01 Lawrence M. Kauvar Glutathione analogs and paralog panels comprising glutathione mimics
US5908919A (en) * 1993-10-01 1999-06-01 Terrapin Technologies Urethane mediated, GST specific molecular release systems
WO1996040205A1 (en) 1995-06-07 1996-12-19 Terrapin Technologies, Inc. Metabolic effects of certain glutathione analogs
AU4124697A (en) * 1996-09-02 1998-03-26 Manchester Metropolitan University, The S-blocked glutathiones
TW576838B (en) * 1998-04-16 2004-02-21 Teijin Ltd Glutathione derivatives and application form thereof
HK1043310B (zh) * 1999-01-27 2005-10-07 泰立克公司 含有谷胱甘肽类似物的治疗用组合物
US7029695B2 (en) * 2001-07-10 2006-04-18 Telik, Inc. Therapeutic compositions containing glutathione analogs
TWI323662B (en) * 2002-11-15 2010-04-21 Telik Inc Combination cancer therapy with a gst-activated anticancer compound and another anticancer therapy
ATE410520T1 (de) 2005-01-06 2008-10-15 Telik Inc Tripeptid- und tetrapeptid-thioether

Also Published As

Publication number Publication date
HRP20090128T3 (hr) 2009-04-30
JP4903717B2 (ja) 2012-03-28
JP2008526859A (ja) 2008-07-24
KR101244609B1 (ko) 2013-03-25
WO2006074249A1 (en) 2006-07-13
PL1833842T3 (pl) 2009-04-30
JP2008526880A (ja) 2008-07-24
CA2587310C (en) 2013-11-12
TW200635949A (en) 2006-10-16
DK1833842T3 (da) 2009-02-09
EP1833842A1 (en) 2007-09-19
US7129215B2 (en) 2006-10-31
WO2006074409A1 (en) 2006-07-13
AR051889A1 (es) 2007-02-14
PL1833978T3 (pl) 2009-04-30
KR20070091611A (ko) 2007-09-11
ATE410520T1 (de) 2008-10-15
IL183107A (en) 2010-11-30
DE602006003063D1 (de) 2008-11-20
EA200701399A1 (ru) 2008-02-28
EP1833842B1 (en) 2008-10-08
CN101090977B (zh) 2013-04-10
HRP20090134T3 (hr) 2009-04-30
HK1106796A1 (en) 2008-03-20
EA200701398A1 (ru) 2007-12-28
AU2006204022A1 (en) 2006-07-13
CA2587284C (en) 2014-03-25
AR051890A1 (es) 2007-02-14
ZA200704487B (en) 2008-09-25
CN101080418A (zh) 2007-11-28
AU2006204022B2 (en) 2011-01-20
EP1833978A1 (en) 2007-09-19
MX2007008254A (es) 2007-09-11
BRPI0606520A2 (pt) 2009-06-30
SI1833978T1 (sl) 2009-04-30
ATE410440T1 (de) 2008-10-15
TWI317739B (en) 2009-12-01
TW200635948A (en) 2006-10-16
ES2314890T3 (es) 2009-03-16
BRPI0606396A2 (pt) 2009-06-23
PT1833842E (pt) 2008-12-11
US20060160749A1 (en) 2006-07-20
MX2007008255A (es) 2007-09-11
NZ555362A (en) 2009-05-31
IL182836A0 (en) 2007-08-19
US7192918B2 (en) 2007-03-20
CA2587310A1 (en) 2006-07-13
US20060148719A1 (en) 2006-07-06
AU2006203901B2 (en) 2011-06-02
NZ555361A (en) 2009-05-31
KR20070104391A (ko) 2007-10-25
AU2006203901A1 (en) 2006-07-13
HK1106778A1 (en) 2008-03-20
IL183107A0 (en) 2007-09-20
ES2314891T3 (es) 2009-03-16
CN101090977A (zh) 2007-12-19
CA2587284A1 (en) 2006-07-13
SI1833842T1 (sl) 2009-04-30
JP4903716B2 (ja) 2012-03-28
WO2006074409A9 (en) 2006-12-14
EP1833978B1 (en) 2008-10-08
IL182836A (en) 2010-11-30
TWI317738B (en) 2009-12-01
DE602006003064D1 (en) 2008-11-20
ZA200704488B (en) 2008-09-25
PT1833978E (pt) 2008-12-02

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